Abstract:
PURPOSE:To assess the urodynamic findings in patients with Parkinson disease (PD) with overactive bladder symptoms. METHODS:We performed a retrospective chart review of all PD patients who were seen in an outpatient clinic for lower urinary tract symptoms (LUTS) between 2010 and 2017 in a single-institution. Only patients who complained of overactive bladder (OAB) symptoms and underwent a video-urodynamic study for these symptoms were included. We excluded patients with neurological disorders other than PD and patients with voiding LUTS but without OAB symptoms. RESULTS:We included 42 patients (29 men, 13 women, 74.5±8.1 years old). Seven patients (16.7%) had a postvoid residual (PVR) bladder volume >100 mL and only one reported incomplete bladder emptying. Detrusor overactivity (DO) was found in all 42 patients (100%) and was terminal in 19 (45.2%) and phasic in 22 patients (52.4%). Eighteen patients had detrusor underactivity (DU) (42.3%). Later age of PD diagnosis was the only parameter associated with DU (P=0.02). Patients with bladder outlet obstruction (BOO) were younger than patients without BOO (70.1 years vs. 76.5 years, P=0.004), had later first sensation of bladder filling (173.5 mL vs. 120.3 mL, P=0.02) and first involuntary detrusor contraction (226.4 mL vs. 130.4 mL, P=0.009). CONCLUSION:DO is almost universal in all patients with PD complaining of OAB symptoms (97.1%). However, a significant percentage of patients also had BOO (36.8%), DU (47%), and increased PVR (16.7%) indicating that neurogenic DO may not be the only cause of OAB symptoms in PD patients.
journal_name
Int Neurourol Jjournal_title
International neurourology journalauthors
Vurture G,Peyronnet B,Palma JA,Sussman RD,Malacarne DR,Feigin A,Palmerola R,Rosenblum N,Frucht S,Kaufmann H,Nitti VW,Brucker BMdoi
10.5213/inj.1938086.043subject
Has Abstractpub_date
2019-09-01 00:00:00pages
211-218issue
3eissn
2093-4777issn
2093-6931pii
inj.1938086.043journal_volume
23pub_type
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journal_title:International neurourology journal
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更新日期:2019-12-01 00:00:00
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journal_title:International neurourology journal
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journal_title:International neurourology journal
pub_type: 杂志文章
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更新日期:2015-06-01 00:00:00
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journal_title:International neurourology journal
pub_type: 杂志文章
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更新日期:2010-12-01 00:00:00
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journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2014.18.3.133
更新日期:2014-09-01 00:00:00
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journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2040318.159
更新日期:2020-09-01 00:00:00
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journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2010.14.4.267
更新日期:2010-12-01 00:00:00
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journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2013.17.2.67
更新日期:2013-06-01 00:00:00
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journal_title:International neurourology journal
pub_type: 杂志文章
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更新日期:2018-06-01 00:00:00
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journal_title:International neurourology journal
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更新日期:2021-01-04 00:00:00
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journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2011.15.2.97
更新日期:2011-06-01 00:00:00
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journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2014.18.4.221
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pub_type: 杂志文章,已发布勘误
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更新日期:2011-09-01 00:00:00
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journal_title:International neurourology journal
pub_type: 杂志文章,评审
doi:10.5213/inj.1632752.376
更新日期:2016-11-01 00:00:00
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journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2013.17.1.34
更新日期:2013-03-01 00:00:00
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pub_type: 杂志文章
doi:10.5213/inj.1836152.076
更新日期:2018-07-01 00:00:00
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journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2015.19.3.178
更新日期:2015-09-01 00:00:00
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journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2010.14.3.133
更新日期:2010-10-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2012-03-01 00:00:00
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更新日期:2015-12-01 00:00:00
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journal_title:International neurourology journal
pub_type: 杂志文章
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更新日期:2018-12-01 00:00:00
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journal_title:International neurourology journal
pub_type: 已发布勘误
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更新日期:2016-12-01 00:00:00
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journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2011.15.1.4
更新日期:2011-03-01 00:00:00
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journal_title:International neurourology journal
pub_type: 杂志文章
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更新日期:2012-06-01 00:00:00
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更新日期:2016-09-01 00:00:00
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journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2011.15.3.120
更新日期:2011-09-01 00:00:00