Urodynamic Mechanisms Underlying Overactive Bladder Symptoms in Patients With Parkinson Disease.

Abstract:

PURPOSE:To assess the urodynamic findings in patients with Parkinson disease (PD) with overactive bladder symptoms. METHODS:We performed a retrospective chart review of all PD patients who were seen in an outpatient clinic for lower urinary tract symptoms (LUTS) between 2010 and 2017 in a single-institution. Only patients who complained of overactive bladder (OAB) symptoms and underwent a video-urodynamic study for these symptoms were included. We excluded patients with neurological disorders other than PD and patients with voiding LUTS but without OAB symptoms. RESULTS:We included 42 patients (29 men, 13 women, 74.5±8.1 years old). Seven patients (16.7%) had a postvoid residual (PVR) bladder volume >100 mL and only one reported incomplete bladder emptying. Detrusor overactivity (DO) was found in all 42 patients (100%) and was terminal in 19 (45.2%) and phasic in 22 patients (52.4%). Eighteen patients had detrusor underactivity (DU) (42.3%). Later age of PD diagnosis was the only parameter associated with DU (P=0.02). Patients with bladder outlet obstruction (BOO) were younger than patients without BOO (70.1 years vs. 76.5 years, P=0.004), had later first sensation of bladder filling (173.5 mL vs. 120.3 mL, P=0.02) and first involuntary detrusor contraction (226.4 mL vs. 130.4 mL, P=0.009). CONCLUSION:DO is almost universal in all patients with PD complaining of OAB symptoms (97.1%). However, a significant percentage of patients also had BOO (36.8%), DU (47%), and increased PVR (16.7%) indicating that neurogenic DO may not be the only cause of OAB symptoms in PD patients.

journal_name

Int Neurourol J

authors

Vurture G,Peyronnet B,Palma JA,Sussman RD,Malacarne DR,Feigin A,Palmerola R,Rosenblum N,Frucht S,Kaufmann H,Nitti VW,Brucker BM

doi

10.5213/inj.1938086.043

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

211-218

issue

3

eissn

2093-4777

issn

2093-6931

pii

inj.1938086.043

journal_volume

23

pub_type

杂志文章
  • Development of Decision Support Formulas for the Prediction of Bladder Outlet Obstruction and Prostatic Surgery in Patients With Lower Urinary Tract Symptom/Benign Prostatic Hyperplasia: Part I, Development of the Formula and its Internal Validation.

    abstract:PURPOSE:As the elderly population increases, a growing number of patients have lower urinary tract symptom (LUTS)/benign prostatic hyperplasia (BPH). The aim of this study was to develop decision support formulas and nomograms for the prediction of bladder outlet obstruction (BOO) and for BOO-related surgical decision-...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1734852.426

    authors: Choo MS,Yoo C,Cho SY,Jeong SJ,Jeong CW,Ku JH,Oh SJ

    更新日期:2017-04-01 00:00:00

  • Mechanisms and prospects of ischemic tolerance induced by cerebral preconditioning.

    abstract::In the brain, brief episodes of ischemia induce tolerance against a subsequent severe episode of ischemia. This phenomenon of endogenous neuroprotection is known as preconditioning-induced ischemic tolerance. The purpose of this review is to summarize the current state of knowledge about mechanisms and potential appli...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2010.14.4.203

    authors: Bhuiyan MI,Kim YJ

    更新日期:2010-12-01 00:00:00

  • Translation and Linguistic Validation of the Korean Version of the Treatment Satisfaction Visual Analogue Scale and the Overactive Bladder Satisfaction With Treatment Questionnaire.

    abstract:PURPOSE:This study reports the development of the Korean Version of the Treatment Satisfaction Visual Analogue Scale (TS-VAS) and the Overactive Bladder Satisfaction with Treatment Questionnaire (OAB-SAT-q) based on the original versions, with subsequent linguistic validation by Korean patients with overactive bladder ...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1734992.496

    authors: Lee HN,Chae JY,Lee HS,Choo MS,Park MG,Lee SY,Oh SJ,Cho SY

    更新日期:2017-12-01 00:00:00

  • Erratum: Increased Expression of Herpes Virus-Encoded hsv1-miR-H18 and hsv2-miR-H9-5p in Cancer-Containing Prostate Tissue Compared to That in Benign Prostate Hyperplasia Tissue.

    abstract::[This corrects the article on p. 122 in vol. 20, PMID: 27377944.]. ...

    journal_title:International neurourology journal

    pub_type: 已发布勘误

    doi:10.5213/inj.1620err.002

    authors: Yun SJ,Jeong P,Kang HW,Shinn HK,Kim YH,Yan C,Choi YK,Kim D,Ryu DH,Ha YS,Kim TH,Kwon TG,Kim JM,Suh SH,Kim SK,Kim SY,Kim ST,Kim WT,Lee OJ,Moon SK,Kim NH,Kim IY,Kim J,Cha HJ,Choi YH,Cha EJ,Kim WJ

    更新日期:2016-12-01 00:00:00

  • Clean Intermittent Self-Catheterization as a Treatment Modality for Urinary Retention: Perceptions of Urologists.

    abstract:PURPOSE:Clean intermittent self-catheterization (CISC) is now considered the gold standard for the management of urinary retention. In the literature, several articles on patients' perspectives on CISC and adherence to this technique have been published. No studies have yet explored the points of view of professional c...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1734824.412

    authors: Weynants L,Hervé F,Decalf V,Kumps C,Pieters R,Troyer B,Everaert K

    更新日期:2017-09-01 00:00:00

  • Long-term Outcomes of Augmentation Cystoplasty in a Pediatric Population With Refractory Bladder Dysfunction: A 12-Year Follow-up Experience at Single Center.

    abstract:PURPOSE:Augmentation cystoplasty (AC) is a surgical procedure used in adults and children with refractory bladder dysfunction, including a small bladder capacity and inadequate bladder compliance, and in whom conservative and medical treatment has failed. This study was aimed to determine the long-term outcomes of AC i...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1836174.087

    authors: Mehmood S,Alhazmi H,Al-Shayie M,Althobity A,Alshammari A,Altaweel WM,Almathami A,Vallasciani S

    更新日期:2018-12-01 00:00:00

  • Treatment of Anterior Vaginal Wall Prolapse Using Transvaginal Anterior Mesh With Apical Fixation: A Prospective Multicenter Study With up to 2 Years of Follow-up.

    abstract:PURPOSE:To evaluate the safety and efficacy of a surgical polypropylene mesh for correction of anterior vaginal prolapse, with or without apical defects, by providing simultaneous reinforcement at the anterior and apical aspects of the vagina with a single-incision approach. METHODS:This was a prospective, multicenter...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1836036.018

    authors: Palma PCR,Monteiro MVC,Ledesma MA,Altuna S,Sardi JJL,Riccetto CLZ

    更新日期:2018-09-01 00:00:00

  • Efficacy of an Alpha-Blocker for the Treatment of Nonneurogenic Voiding Dysfunction in Women: An 8-Week, Randomized, Double-Blind, Placebo-Controlled Trial.

    abstract:PURPOSE:To evaluate the efficacy of an alpha-1 adrenergic receptor (α1-AR) blocker for the treatment of female voiding dysfunction (FVD) through a pressure-flow study. METHODS:This was a randomized, double-blind, placebo-controlled trial. Women aged ≥18 years with voiding symptoms, as defined by an American Urological...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1834904.452

    authors: Lee YS,Lee KS,Choo MS,Kim JC,Lee JG,Seo JT,Lee JZ,Lee JY,Oh SJ,Na YG

    更新日期:2018-03-01 00:00:00

  • Correlation Between Testosterone-Replacement Treatment and Lower Urinary Tract Symptoms.

    abstract::Lower urinary tract symptoms (LUTS) are a cluster of voiding symptoms, such as weak stream, hesitancy, intermittency, urinary frequency, urgency, and nocturia. LUTS are frequent in elderly men and it considered the ultimate clinical symptoms of benign prostatic hyperplasia. With aging, male hypogonadism is increased w...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2040234.117

    authors: Lee MH,Shin YS,Kam SC

    更新日期:2021-01-19 00:00:00

  • Effect of Nerve-Sparing Radical Prostatectomy on Urinary Continence in Patients With Preoperative Erectile Dysfunction.

    abstract:PURPOSE:We aimed to assess whether nerve-sparing radical prostatectomy (nsRP) is associated with improved recovery of urinary continence compared to non-nerve-sparing radical prostatectomy (nnsRP) in patients with localized prostate cancer and preoperative erectile dysfunction. METHODS:A total of 360 patients with org...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1630428.214

    authors: Park YH,Kwon OS,Hong SH,Kim SW,Hwang TK,Lee JY

    更新日期:2016-03-01 00:00:00

  • Knowledge and Practice Behaviors Regarding Urinary Incontinence Among Korean Healthcare Providers in Long-term Care Hospitals.

    abstract:PURPOSE:The purpose of this study was to assess the current management status of patients with urological issues and to examine the level of knowledge and practice behaviors regarding urinary incontinence (UI) among Korean healthcare providers in long-term care hospitals. METHODS:This study used a cross-sectional desc...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2015.19.4.259

    authors: Jang Y,Kwon BE,Kim HS,Lee YJ,Lee S,Kim SJ,Jeong CW,Kim KH

    更新日期:2015-12-01 00:00:00

  • Aerobic exercise affects myostatin expression in aged rat skeletal muscles: a possibility of antiaging effects of aerobic exercise related with pelvic floor muscle and urethral rhabdosphincter.

    abstract:PURPOSE:Aging-induced loss of muscle mass and subsequent reduction of strength is a fundamental cause of frailty, functional decline, and disability. And this may lead to muscular dysfunction, voiding dysfunction, or urinary incontinence due to pelvic muscle weakness induced by aging. Physical exercise has been recomme...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2014.18.2.77

    authors: Ko IG,Jeong JW,Kim YH,Jee YS,Kim SE,Kim SH,Jin JJ,Kim CJ,Chung KJ

    更新日期:2014-06-01 00:00:00

  • Uroplakins in the lower urinary tract.

    abstract::The apical surface of mammalian urinary epithelium is covered by numerous scallop-shaped membrane plaques. This plaque consists of four different uroplakins (UPs) and integral membrane proteins. UPs, which are a member of the tetraspanin superfamily, are assembled into plaques that act as an exceptional barrier to wat...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2011.15.1.4

    authors: Lee G

    更新日期:2011-03-01 00:00:00

  • Socioeconomic costs of overactive bladder and stress urinary incontinence in Korea.

    abstract:PURPOSE:We quantified and described the economic burden of overactive bladder and stress urinary incontinence in Korea. We calculated direct costs by identifying public and private data sources that contain population-based data on resource utilization by patients with stress urinary incontinence and overactive bladder...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2012.16.1.23

    authors: Sung W,You H,Yoon TY,Lee SJ

    更新日期:2012-03-01 00:00:00

  • The Efficacy of Continuous Positive Airway Pressure Therapy on Nocturia in Patients With Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis.

    abstract:PURPOSE:To assess the efficacy of the continuous positive airway pressure (CPAP) on nocturia in patients with obstructive sleep apnea (OSA). METHODS:A literature review was performed to identify all published clinical trials of CPAP for the treatment of nocturia. The search included the following databases: MEDLINE, E...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2015.19.3.178

    authors: Wang T,Huang W,Zong H,Zhang Y

    更新日期:2015-09-01 00:00:00

  • Bicycle riding: impact on lower urinary tract symptoms and erectile function in healthy men.

    abstract:PURPOSE:Recently, reports in the mass media have implicated that bicycle riding increases the risk of erectile dysfunction and prostatic diseases. So, we evaluate the impact of bicycle riding on erectile function and lower urinary tract symptoms (LUTS) in healthy general men. METHODS:From 26 June 2010 to 20 July 2010,...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2011.15.2.97

    authors: Baek S,Lee SY,Kim JM,Shin E,Kam S,Jung HC

    更新日期:2011-06-01 00:00:00

  • Obesity as a Risk Factor for Prostatic Enlargement: A Retrospective Cohort Study in Korea.

    abstract:PURPOSE:We aimed to evaluate obesity, a risk factor of metabolic syndrome, and its association with prostatic enlargement in a retrospective cohort in Korea. METHODS:Baseline data were obtained from the Korean Genome and Epidemiology Study on Atherosclerosis Risk of Rural Areas in the Korean General Population (KoGES-...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1632584.292

    authors: Jung JH,Ahn SV,Song JM,Chang SJ,Kim KJ,Kwon SW,Park SY,Koh SB

    更新日期:2016-12-01 00:00:00

  • Innovative Distribution Priorities for the Medical Devices Industry in the Fourth Industrial Revolution.

    abstract:PURPOSE:This study aimed to set priorities for improving the medical device distribution structure and to suggest an innovative improvement plan for the distribution structure using the analytic hierarchy process (AHP) method, focusing on stakeholders in the medical device industry. METHODS:This study conducted a surv...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1836152.076

    authors: Lee M,Yoon Y,Ryu GH,Bok HS,Yoon K,Park S,Lee KS

    更新日期:2018-07-01 00:00:00

  • Clinical Factors Associated With the Feeling of Incomplete Bladder Emptying in Women With Little Postvoided Residue.

    abstract:PURPOSE:To investigate the clinical factors associated with the feeling of incomplete bladder emptying in female patients with lower urinary tract symptoms (LUTS). METHODS:Records were obtained from a prospectively maintained database for 353 female patients without a history of treatment for LUTS. Patients with comor...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1938256.128

    authors: Lee KS,Koo KC

    更新日期:2020-06-01 00:00:00

  • Computer-Assisted Lead Placement for Peripheral Nerve Evaluation Test in a Candidate for Sacral Neuromodulation.

    abstract::Our aim was to report the first case of computer-assisted lead placement (CALP) for a peripheral nerve evaluation (PNE) test in a 55-year-old woman affected by chronic pelvic pain, who was a candidate for sacral neuromodulation (SNM). The first PNE test failed due to nonoptimal lead placement. We utilized a surgical n...

    journal_title:International neurourology journal

    pub_type:

    doi:10.5213/inj.2040096.048

    authors: Sampogna G,Montanari E,Spinelli M

    更新日期:2020-12-01 00:00:00

  • On the Site and Mechanism of Action of β3-Adrenoceptor Agonists in the Bladder.

    abstract::The clinical success of mirabegron as the first β3-adrenoceptor (AR) agonist for treatment of the overactive bladder (OAB) syndrome, has resulted in substantial interest in its site and mechanism of action. Even if the adrenergic innervation of the bladder and urethra has been well studied, the location(s) of β3-ARs i...

    journal_title:International neurourology journal

    pub_type: 杂志文章,评审

    doi:10.5213/inj.1734850.425

    authors: Andersson KE

    更新日期:2017-03-24 00:00:00

  • Neuroprotective Effects of Bone Marrow Stromal Cell Transplantation in Combination With Treadmill Exercise Following Traumatic Brain Injury.

    abstract:PURPOSE:Traumatic brain injury (TBI) causes cognitive impairments, motor deficits, and neuropsychiatric/behavioral deficits problems. Transplantation of bone marrow stromal cells (BMSCs) facilitates functional recovery from brain insults. Treadmill exercise increases neurogenesis and inhibits apoptosis. In this study, ...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1632616.308

    authors: Shin MS,Park HK,Kim TW,Ji ES,Lee JM,Choi HS,Kim MY,Kim YP

    更新日期:2016-05-01 00:00:00

  • 4-aminopyridine improves lower urinary tract symptoms in a patient with benign prostatic hyperplasia and downbeat nystagmus syndrome.

    abstract::Aminopyridines are potassium channel blockers that increase the excitability of nerve cells and axons; therefore, they are widely used to treat different neurological disorders. Here we present a patient with idiopathic downbeat nystagmus and lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia who ...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2014.18.4.221

    authors: Strupp M,Feil K,Bardins S,Waidelich R

    更新日期:2014-12-01 00:00:00

  • Effects of Acute Sacral Neuromodulation at Different Pulse Widths on Bladder Overactivity in Pigs.

    abstract:PURPOSE:Sacral nerve stimulation has been used to treat overactive bladder. This study evaluated the effects of stimulation using different pulse widths on the inhibition of bladder overactivity by sacral nerve stimulation (SNM) in pigs. METHODS:Implant-driven stimulators were used to stimulate the S3 spinal nerve in ...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1938042.021

    authors: Cong H,Liao L,Wang Y,Zhao L,Wang Z,Fu G,Chen G

    更新日期:2019-06-01 00:00:00

  • Role of Transcutaneous Electrical Nerve Stimulation in Treating Children With Overactive Bladder From Pooled Analysis of 8 Randomized Controlled Trials.

    abstract:PURPOSE:Transcutaneous electrical neural stimulation (TENS), as a non-invasive modality, has been clinically used as an alternative treatment for children with overactive bladder (OAB). We conducted a pooled analysis to explore the effect of TENS on OAB. METHODS:The Preferred Reporting Items for Systematic Reviews and...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1938232.116

    authors: Cui H,Yao Y,Xu Z,Gao Z,Wu J,Zhou Z,Cui Y

    更新日期:2020-03-01 00:00:00

  • Electroanatomical Mapping of the Urinary Bladder.

    abstract::A noncontact mapping system (EnSite) was used for electroanatomical mapping of the bladder simultaneously with pressure flow study in three women with lower urinary tract symptoms. We selected the periods of obvious detrusor activity. Data were processed to remove baseline drift, and an envelope of electrovesicography...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1630504.252

    authors: Farag F,Koens M,Tijssen M,Jong Sd,Fabius T,Tromp J,Breda Hv,Smeets J,Feitz W,Heesakkers J

    更新日期:2016-06-01 00:00:00

  • Quality of life of women with urinary incontinence: a systematic literature review.

    abstract:PURPOSE:The purpose of this study was to review studies that have examined the quality of life of women with urinary incontinence. MATERIALS AND METHODS:A review was conducted that used the databases PubMED, Proquest, CINAHL, and Sciencedirect. Articles were included that were published in English between 2005 and 201...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2010.14.3.133

    authors: Kwon BE,Kim GY,Son YJ,Roh YS,You MA

    更新日期:2010-10-01 00:00:00

  • Past, Present, and Future in the Study of Neural Control of the Lower Urinary Tract.

    abstract::The neurological coordination of the lower urinary tract can be analyzed from the perspective of motor neurons or sensory neurons. First, sensory nerves with receptors in the bladder and urethra transmits stimuli to the cerebral cortex through the periaqueductal gray (PAG) of the midbrain. Upon the recognition of stim...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.2040318.159

    authors: Kim JW,Kim SJ,Park JM,Na YG,Kim KH

    更新日期:2020-09-01 00:00:00

  • Overview of the Epidemiology of Lower Urinary Tract Dysfunction in South Korea.

    abstract::This review assessed the epidemiology of voiding dysfunctions in South Korea. Comprehensive understanding of this epidemiology is crucial because the senior population and the social burden are increasing because of voiding dysfunctions is growing. We searched the medical records using several terms related to voiding...

    journal_title:International neurourology journal

    pub_type: 杂志文章,评审

    doi:10.5213/inj.1630502.251

    authors: Choi H,Bae JH

    更新日期:2016-06-01 00:00:00

  • Neurologic Mechanisms Underlying Voiding Dysfunction due to Prostatitis in a Rat Model of Nonbacterial Prostatic Inflammation.

    abstract:PURPOSE:The neurological molecular mechanisms underlying the voiding dysfunction associated with nonbacterial chronic prostatitis/chronic pelvic pain syndrome remain poorly understood. In this study, we assessed whether prostate inflammation activated bladder afferent neurons, leading to bladder dysfunction, and sought...

    journal_title:International neurourology journal

    pub_type: 杂志文章

    doi:10.5213/inj.1836124.062

    authors: Park JS,Jin MH,Hong CH

    更新日期:2018-06-01 00:00:00