Abstract：
PURPOSE:We aimed to assess whether nerve-sparing radical prostatectomy (nsRP) is associated with improved recovery of urinary continence compared to non-nerve-sparing radical prostatectomy (nnsRP) in patients with localized prostate cancer and preoperative erectile dysfunction. METHODS:A total of 360 patients with organ-confined prostate cancer and an International Index of Erectile Function score of less than 17 were treated with nsRP or nnsRP in Seoul St. Mary's Hospital. Patients who received neoadjuvant or adjuvant androgen deprivation therapy or had a history of prostate-related surgery were excluded. Recovery of urinary continence was assessed at 0, 1, 3, 6, and 12 months. Postoperative recovery of continence was defined as zero pad usage. The association between nerve-sparing status and urinary continence was assessed by using univariate and multivariate Cox regression analyses after controlling for known predictive factors. RESULTS:Urinary continence recovered in 279 patients (77.5%) within the mean follow-up period of 22.5 months (range, 6-123 months). Recovery of urinary continence was reported in 74.6% and 86.4% of patients after nnsRP and nsRP, respectively, at 12 months (P=0.022). All groups had comparable perioperative criteria and had no significant preoperative morbidities. Age, American Society of Anesthesiologists score, and nerve-sparing status were significantly associated with recovery of urinary continence on univariate analysis. On multivariate analysis, age (hazard ratio [HR], 1.254; 95% confidence interval [CI], 1.002-1.478; P=0.026) and nerve-sparing status (HR, 0.713; 95% CI, 0.548-0.929; P=0.012) were independently associated with recovery of urinary continence. CONCLUSIONS:nsRP, as compared to nnsRP, improves recovery rates of urinary incontinence and decreases surgical morbidity without compromising pathologic outcomes.
journal_name
Int Neurourol Jjournal_title
International neurourology journalauthors
Park YH,Kwon OS,Hong SH,Kim SW,Hwang TK,Lee JYdoi
10.5213/inj.1630428.214subject
Has Abstractpub_date
2016-03-01 00:00:00pages
69-74issue
1eissn
2093-4777issn
2093-6931pii
inj-1630428-214journal_volume
20pub_type
杂志文章abstract：PURPOSE:The neurological molecular mechanisms underlying the voiding dysfunction associated with nonbacterial chronic prostatitis/chronic pelvic pain syndrome remain poorly understood. In this study, we assessed whether prostate inflammation activated bladder afferent neurons, leading to bladder dysfunction, and sought...
journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.1836124.062
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abstract：PURPOSE:Sacral nerve stimulation has been used to treat overactive bladder. This study evaluated the effects of stimulation using different pulse widths on the inhibition of bladder overactivity by sacral nerve stimulation (SNM) in pigs. METHODS:Implant-driven stimulators were used to stimulate the S3 spinal nerve in ...
journal_title：International neurourology journal
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doi：10.5213/inj.1938042.021
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abstract：:Lower urinary tract symptoms (LUTS) are a cluster of voiding symptoms, such as weak stream, hesitancy, intermittency, urinary frequency, urgency, and nocturia. LUTS are frequent in elderly men and it considered the ultimate clinical symptoms of benign prostatic hyperplasia. With aging, male hypogonadism is increased w...
journal_title：International neurourology journal
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doi：10.5213/inj.2040234.117
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journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.1834904.452
更新日期：2018-03-01 00:00:00
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journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.2014.18.2.77
更新日期：2014-06-01 00:00:00
abstract：:A noncontact mapping system (EnSite) was used for electroanatomical mapping of the bladder simultaneously with pressure flow study in three women with lower urinary tract symptoms. We selected the periods of obvious detrusor activity. Data were processed to remove baseline drift, and an envelope of electrovesicography...
journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.1630504.252
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abstract：:Parkinson disease (PD) is the second most prevalent neurodegenerative disorder after Alzheimer disease. The loss of specific brain area, the substantia nigra pars compacta is known as a major etiology, however it is not fully understood how this neurodegeneration is initiated and what precisely causes this disease. As...
journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.1836216.108
更新日期：2018-10-01 00:00:00
abstract：:Aminopyridines are potassium channel blockers that increase the excitability of nerve cells and axons; therefore, they are widely used to treat different neurological disorders. Here we present a patient with idiopathic downbeat nystagmus and lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia who ...
journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.2014.18.4.221
更新日期：2014-12-01 00:00:00
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journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.1938056.028
更新日期：2019-03-01 00:00:00
abstract：PURPOSE:To evaluate disease insight, personal distress, and healthcare-seeking behavior of women with urinary incontinence (UI) to improve women's health in Korea. METHODS:In October 2012, 500 Korean women residing around Seoul, Incheon, and Gyeonggi-do were selected by random sampling for a population-based cross-sec...
journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.2015.19.1.39
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journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.2010.14.4.267
更新日期：2010-12-01 00:00:00
abstract：PURPOSE:Transcutaneous electrical neural stimulation (TENS), as a non-invasive modality, has been clinically used as an alternative treatment for children with overactive bladder (OAB). We conducted a pooled analysis to explore the effect of TENS on OAB. METHODS:The Preferred Reporting Items for Systematic Reviews and...
journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.1938232.116
更新日期：2020-03-01 00:00:00
abstract：:Our aim was to report the first case of computer-assisted lead placement (CALP) for a peripheral nerve evaluation (PNE) test in a 55-year-old woman affected by chronic pelvic pain, who was a candidate for sacral neuromodulation (SNM). The first PNE test failed due to nonoptimal lead placement. We utilized a surgical n...
journal_title：International neurourology journal
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doi：10.5213/inj.2040096.048
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:We aimed to evaluate obesity, a risk factor of metabolic syndrome, and its association with prostatic enlargement in a retrospective cohort in Korea. METHODS:Baseline data were obtained from the Korean Genome and Epidemiology Study on Atherosclerosis Risk of Rural Areas in the Korean General Population (KoGES-...
journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.1632584.292
更新日期：2016-12-01 00:00:00
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journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.1732686.343
更新日期：2017-06-01 00:00:00
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journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.2015.19.3.178
更新日期：2015-09-01 00:00:00
abstract：PURPOSE:Benign prostatic hyperplasia is often accompanied by age-related comorbidity, such as erectile dysfunction (ED). Recent data suggest an association between ED and lower urinary tract symptoms (LUTS), and increasing evidence indicates that the clinical use of phosphodiesterase type 5 (PDE5) inhibitors provides r...
journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.2010.14.1.7
更新日期：2010-04-01 00:00:00
abstract：PURPOSE:In this study, we compared the treatment outcomes for an α-blocker between 2 groups of men, one with high sympathetic activity (HSA) and another with low sympathetic activity (LSA) or normal sympathetic activity. METHODS:A total of 159 men (≥50 years of age) with lower urinary tract symptoms resulting from ben...
journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.2015.19.2.107
更新日期：2015-06-01 00:00:00
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journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.2011.15.2.97
更新日期：2011-06-01 00:00:00
abstract：:In the brain, brief episodes of ischemia induce tolerance against a subsequent severe episode of ischemia. This phenomenon of endogenous neuroprotection is known as preconditioning-induced ischemic tolerance. The purpose of this review is to summarize the current state of knowledge about mechanisms and potential appli...
journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.2010.14.4.203
更新日期：2010-12-01 00:00:00
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journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.2040318.159
更新日期：2020-09-01 00:00:00
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journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.1938110.055
更新日期：2019-12-01 00:00:00
abstract：:The clinical success of mirabegron as the first β3-adrenoceptor (AR) agonist for treatment of the overactive bladder (OAB) syndrome, has resulted in substantial interest in its site and mechanism of action. Even if the adrenergic innervation of the bladder and urethra has been well studied, the location(s) of β3-ARs i...
journal_title：International neurourology journal
pub_type： 杂志文章,评审
doi：10.5213/inj.1734850.425
更新日期：2017-03-24 00:00:00
abstract：PURPOSE:The purpose of this study was to assess the current management status of patients with urological issues and to examine the level of knowledge and practice behaviors regarding urinary incontinence (UI) among Korean healthcare providers in long-term care hospitals. METHODS:This study used a cross-sectional desc...
journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.2015.19.4.259
更新日期：2015-12-01 00:00:00
abstract：PURPOSE:As the elderly population increases, a growing number of patients have lower urinary tract symptom (LUTS)/benign prostatic hyperplasia (BPH). The aim of this study was to develop decision support formulas and nomograms for the prediction of bladder outlet obstruction (BOO) and for BOO-related surgical decision-...
journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.1734852.426
更新日期：2017-04-01 00:00:00
abstract：PURPOSE:Lower urinary tract dysfunction is the most common complication after radical pelvic surgery. The aims of this study were to assess the effect of radical hysterectomy (RH) on the storage function of the lower urinary tract and to evaluate the impact of radiation therapy (RT) on postoperative urodynamic paramete...
journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.2012.16.2.91
更新日期：2012-06-01 00:00:00
abstract：:[This corrects the article on p. 122 in vol. 20, PMID: 27377944.]. ...
journal_title：International neurourology journal
pub_type： 已发布勘误
doi：10.5213/inj.1620err.002
更新日期：2016-12-01 00:00:00
abstract：PURPOSE:To evaluate the safety and efficacy of a surgical polypropylene mesh for correction of anterior vaginal prolapse, with or without apical defects, by providing simultaneous reinforcement at the anterior and apical aspects of the vagina with a single-incision approach. METHODS:This was a prospective, multicenter...
journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.1836036.018
更新日期：2018-09-01 00:00:00
abstract：PURPOSE:We investigated bladder function, with a special focus on nonvoiding contractions (NVCs), in awake rats with chronic chemical cystitis and bladder outlet obstruction (BOO) by use of simultaneous registrations of intravesical and intraabdominal pressures. In addition, we tested the effects of tolterodine on the ...
journal_title：International neurourology journal
pub_type： 杂志文章
doi：10.5213/inj.2011.15.3.120
更新日期：2011-09-01 00:00:00
abstract：:This review assessed the epidemiology of voiding dysfunctions in South Korea. Comprehensive understanding of this epidemiology is crucial because the senior population and the social burden are increasing because of voiding dysfunctions is growing. We searched the medical records using several terms related to voiding...
journal_title：International neurourology journal
pub_type： 杂志文章,评审
doi：10.5213/inj.1630502.251
更新日期：2016-06-01 00:00:00
