Abstract:
:Bladder cancer is one of the most common cancers worldwide, with a high rate of recurrence and poor outcomes as a result of relapse. Bladder cancer patients require lifelong invasive monitoring and treatment, making bladder cancer one of the most expensive malignancies. Lines of evidence increasingly point to distinct genetic and epigenetic alteration patterns in bladder cancer, even between the different stages and grades of disease. In addition, genetic and epigenetic alterations have been demonstrated to play important roles during bladder tumorigenesis. This review will focus on bladder cancer-associated genomic and epigenomic alterations, which are common in bladder cancer and provide potential diagnostic markers and therapeutic targets for bladder cancer treatment.
journal_name
Int Neurourol Jjournal_title
International neurourology journalauthors
Li HT,Duymich CE,Weisenberger DJ,Liang Gdoi
10.5213/inj.1632752.376subject
Has Abstractpub_date
2016-11-01 00:00:00pages
S84-94issue
Suppl 2eissn
2093-4777issn
2093-6931pii
inj-1632752-376journal_volume
20pub_type
杂志文章,评审abstract:PURPOSE:Augmentation cystoplasty (AC) is a surgical procedure used in adults and children with refractory bladder dysfunction, including a small bladder capacity and inadequate bladder compliance, and in whom conservative and medical treatment has failed. This study was aimed to determine the long-term outcomes of AC i...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1836174.087
更新日期:2018-12-01 00:00:00
abstract:PURPOSE:This study reports the development of the Korean Version of the Treatment Satisfaction Visual Analogue Scale (TS-VAS) and the Overactive Bladder Satisfaction with Treatment Questionnaire (OAB-SAT-q) based on the original versions, with subsequent linguistic validation by Korean patients with overactive bladder ...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1734992.496
更新日期:2017-12-01 00:00:00
abstract:PURPOSE:Lower urinary tract dysfunction is the most common complication after radical pelvic surgery. The aims of this study were to assess the effect of radical hysterectomy (RH) on the storage function of the lower urinary tract and to evaluate the impact of radiation therapy (RT) on postoperative urodynamic paramete...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2012.16.2.91
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:To review the clinical outcomes of patients with voiding dysfunction who have detrusor overactivity with impaired contractility (DOIC) diagnosed with urodynamic studies. METHODS:Urodynamic reports from 2005 to 2009 were reviewed, and 54 male patients had findings consistent with DOIC. Patients with acontractil...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2014.18.3.133
更新日期:2014-09-01 00:00:00
abstract::Lower urinary tract symptoms (LUTS) are a cluster of voiding symptoms, such as weak stream, hesitancy, intermittency, urinary frequency, urgency, and nocturia. LUTS are frequent in elderly men and it considered the ultimate clinical symptoms of benign prostatic hyperplasia. With aging, male hypogonadism is increased w...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2040234.117
更新日期:2021-01-19 00:00:00
abstract:PURPOSE:To evaluate the efficacy of an alpha-1 adrenergic receptor (α1-AR) blocker for the treatment of female voiding dysfunction (FVD) through a pressure-flow study. METHODS:This was a randomized, double-blind, placebo-controlled trial. Women aged ≥18 years with voiding symptoms, as defined by an American Urological...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1834904.452
更新日期:2018-03-01 00:00:00
abstract::Parkinson disease (PD) is the second most prevalent neurodegenerative disorder after Alzheimer disease. The loss of specific brain area, the substantia nigra pars compacta is known as a major etiology, however it is not fully understood how this neurodegeneration is initiated and what precisely causes this disease. As...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1836216.108
更新日期:2018-10-01 00:00:00
abstract:PURPOSE:To evaluate the effects of botulinum toxin on urodynamic parameters and quality of life in patients with neurogenic detrusor overactivity. METHODS:Thirty four adult patients with spinal cord injury and detrusor overactivity were selected. The patients received 300 units of botulinum toxin type A. The endpoints...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2012.16.3.139
更新日期:2012-09-01 00:00:00
abstract::This review assessed the epidemiology of voiding dysfunctions in South Korea. Comprehensive understanding of this epidemiology is crucial because the senior population and the social burden are increasing because of voiding dysfunctions is growing. We searched the medical records using several terms related to voiding...
journal_title:International neurourology journal
pub_type: 杂志文章,评审
doi:10.5213/inj.1630502.251
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:Aging-induced loss of muscle mass and subsequent reduction of strength is a fundamental cause of frailty, functional decline, and disability. And this may lead to muscular dysfunction, voiding dysfunction, or urinary incontinence due to pelvic muscle weakness induced by aging. Physical exercise has been recomme...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2014.18.2.77
更新日期:2014-06-01 00:00:00
abstract:PURPOSE:To assess the efficacy of the continuous positive airway pressure (CPAP) on nocturia in patients with obstructive sleep apnea (OSA). METHODS:A literature review was performed to identify all published clinical trials of CPAP for the treatment of nocturia. The search included the following databases: MEDLINE, E...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2015.19.3.178
更新日期:2015-09-01 00:00:00
abstract:PURPOSE:Maintaining urinary continence at stress requires a competent urethral sphincter and good suburethral support. Sphincter competence is estimated by measuring the maximal urethral closure pressure at rest. We aimed to study the value of a new urodynamic measure, the urethral closure pressure at stress (s-UCP), i...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1732686.343
更新日期:2017-06-01 00:00:00
abstract:PURPOSE:The purpose of this study was to assess the current management status of patients with urological issues and to examine the level of knowledge and practice behaviors regarding urinary incontinence (UI) among Korean healthcare providers in long-term care hospitals. METHODS:This study used a cross-sectional desc...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2015.19.4.259
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:Hypoxia-mediated neurotoxicity contributes to various neurodegenerative disorders, including Alzheimer disease. Neuregulin-1 (NRG1) plays an important role in the development and plasticity of the brain. The aim of the present study was to investigate the neuroprotective effect and the regulating hypoxic induci...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1938190.095
更新日期:2019-11-01 00:00:00
abstract:PURPOSE:To assess the urodynamic findings in patients with Parkinson disease (PD) with overactive bladder symptoms. METHODS:We performed a retrospective chart review of all PD patients who were seen in an outpatient clinic for lower urinary tract symptoms (LUTS) between 2010 and 2017 in a single-institution. Only pati...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1938086.043
更新日期:2019-09-01 00:00:00
abstract:PURPOSE:In this study, we compared the treatment outcomes for an α-blocker between 2 groups of men, one with high sympathetic activity (HSA) and another with low sympathetic activity (LSA) or normal sympathetic activity. METHODS:A total of 159 men (≥50 years of age) with lower urinary tract symptoms resulting from ben...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2015.19.2.107
更新日期:2015-06-01 00:00:00
abstract::The apical surface of mammalian urinary epithelium is covered by numerous scallop-shaped membrane plaques. This plaque consists of four different uroplakins (UPs) and integral membrane proteins. UPs, which are a member of the tetraspanin superfamily, are assembled into plaques that act as an exceptional barrier to wat...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2011.15.1.4
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:The neurological molecular mechanisms underlying the voiding dysfunction associated with nonbacterial chronic prostatitis/chronic pelvic pain syndrome remain poorly understood. In this study, we assessed whether prostate inflammation activated bladder afferent neurons, leading to bladder dysfunction, and sought...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1836124.062
更新日期:2018-06-01 00:00:00
abstract::The neurological coordination of the lower urinary tract can be analyzed from the perspective of motor neurons or sensory neurons. First, sensory nerves with receptors in the bladder and urethra transmits stimuli to the cerebral cortex through the periaqueductal gray (PAG) of the midbrain. Upon the recognition of stim...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2040318.159
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:Ketamine may decrease core-to-peripheral redistribution of heat through direct central sympathetic stimulation and inhibition of norepinephrine uptake into postganglionic sympathetic nerve endings. The purpose of this study was to evaluate the efficacy of epidural ketamine in preventing shivering during transur...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2010.14.2.105
更新日期:2010-08-01 00:00:00
abstract:PURPOSE:This study aimed to set priorities for improving the medical device distribution structure and to suggest an innovative improvement plan for the distribution structure using the analytic hierarchy process (AHP) method, focusing on stakeholders in the medical device industry. METHODS:This study conducted a surv...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1836152.076
更新日期:2018-07-01 00:00:00
abstract:PURPOSE:To evaluate whether hydrodistention with fulguration of Hunner lesions (HD/FUL) plus maintenance dimethyl sulfoxide (DMSO) therapy prolongs the recurrence-free time in patients with Hunner type interstitial cystitis (IC). METHODS:The study enrolled patients with Hunner type IC who required repeat HD/FUL due to...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1938110.055
更新日期:2019-12-01 00:00:00
abstract:PURPOSE:Transcutaneous electrical neural stimulation (TENS), as a non-invasive modality, has been clinically used as an alternative treatment for children with overactive bladder (OAB). We conducted a pooled analysis to explore the effect of TENS on OAB. METHODS:The Preferred Reporting Items for Systematic Reviews and...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1938232.116
更新日期:2020-03-01 00:00:00
abstract:PURPOSE:We aimed to assess whether nerve-sparing radical prostatectomy (nsRP) is associated with improved recovery of urinary continence compared to non-nerve-sparing radical prostatectomy (nnsRP) in patients with localized prostate cancer and preoperative erectile dysfunction. METHODS:A total of 360 patients with org...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.1630428.214
更新日期:2016-03-01 00:00:00
abstract::[This corrects the article on p. 122 in vol. 20, PMID: 27377944.]. ...
journal_title:International neurourology journal
pub_type: 已发布勘误
doi:10.5213/inj.1620err.002
更新日期:2016-12-01 00:00:00
abstract::[This corrects the article on p. 164 in vol. 14, PMID: 21179334.]. ...
journal_title:International neurourology journal
pub_type: 杂志文章,已发布勘误
doi:10.5213/inj.2011.15.3.181
更新日期:2011-09-01 00:00:00
abstract::In the brain, brief episodes of ischemia induce tolerance against a subsequent severe episode of ischemia. This phenomenon of endogenous neuroprotection is known as preconditioning-induced ischemic tolerance. The purpose of this review is to summarize the current state of knowledge about mechanisms and potential appli...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2010.14.4.203
更新日期:2010-12-01 00:00:00
abstract:PURPOSE:Bladder wall thickness has been reported to be associated with overactive bladder (OAB) in women. Diabetic women have an increased risk for OAB syndrome and may have an increased risk for bladder wall thickness. METHODS:A total of 235 female patients aged 40 to 75 years were categorized into four groups. The f...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2013.17.2.67
更新日期:2013-06-01 00:00:00
abstract::Our aim was to report the first case of computer-assisted lead placement (CALP) for a peripheral nerve evaluation (PNE) test in a 55-year-old woman affected by chronic pelvic pain, who was a candidate for sacral neuromodulation (SNM). The first PNE test failed due to nonoptimal lead placement. We utilized a surgical n...
journal_title:International neurourology journal
pub_type:
doi:10.5213/inj.2040096.048
更新日期:2020-12-01 00:00:00
abstract:PURPOSE:We studied the influence of preoperative bladder outlet obstruction (BOO) on postoperative continence rates and patient satisfaction after the midurethral sling procedure. METHODS:A total of 159 women who underwent the midurethral sling procedure were evaluated. Using the Blaivas-Groutz nomogram, we assigned t...
journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2010.14.4.267
更新日期:2010-12-01 00:00:00