Abstract:
PURPOSE:Augmentation cystoplasty (AC) is a surgical procedure used in adults and children with refractory bladder dysfunction, including a small bladder capacity and inadequate bladder compliance, and in whom conservative and medical treatment has failed. This study was aimed to determine the long-term outcomes of AC in children. METHODS:A retrospective analysis was conducted of 42 patients (31 males; mean age, 14.2±6.2 years) who underwent AC for neurogenic and nonneurogenic bladder dysfunction, with a median 12.0±1.5 years of follow-up. All patients underwent AC using the ileum with or without continent reconstruction. Pre-AC, concurrent, and post-AC procedures and complications were analyzed. Patients who underwent ureterocystoplasty, were lost to follow-up, or had less than 10 years of follow-up were excluded. The primary outcomes were the complication and continence rates, the post-AC linear rate of height and weight gain, and renal function. The Student t-test was used to evaluate between-group differences and the paired t-test was used to evaluate longitudinal changes in measured variables. RESULTS:Renal function was stable or improved in 32 of 42 patients (76.2%), with a post-AC continence rate of 88.1%. Thirty patients (71.4%) required 72 procedures post-AC. There was no statistically significant difference in the mean percentile of height (P=0. 212) or weight (P=0.142) of patients in the pre- and post-AC periods. No cases of bladder perforation or malignancy were detected. CONCLUSION:We consider AC to be a safe and effective procedure that does not negatively affect future physical growth, while achieving a good rate of stable renal function. Patients need long-term follow-up to address long-term complications.
journal_name
Int Neurourol Jjournal_title
International neurourology journalauthors
Mehmood S,Alhazmi H,Al-Shayie M,Althobity A,Alshammari A,Altaweel WM,Almathami A,Vallasciani Sdoi
10.5213/inj.1836174.087subject
Has Abstractpub_date
2018-12-01 00:00:00pages
287-294issue
4eissn
2093-4777issn
2093-6931pii
inj.1836174.087journal_volume
22pub_type
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pub_type: 杂志文章
doi:10.5213/inj.2015.19.3.178
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journal_title:International neurourology journal
pub_type: 已发布勘误
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pub_type: 杂志文章
doi:10.5213/inj.1632616.308
更新日期:2016-05-01 00:00:00
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doi:10.5213/inj.1630428.214
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journal_title:International neurourology journal
pub_type: 杂志文章
doi:10.5213/inj.2010.14.4.267
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pub_type: 杂志文章
doi:10.5213/inj.1734852.426
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pub_type: 杂志文章
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journal_title:International neurourology journal
pub_type: 杂志文章
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更新日期:2018-03-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2016-12-01 00:00:00
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journal_title:International neurourology journal
pub_type: 杂志文章,评审
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更新日期:2016-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-06-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2017-03-24 00:00:00