Abstract:
:Primary malignant lymphomas of the salivary glands are rare, accounting for 2-5% of salivary gland tumors and 5% of extranodal lymphomas, frequently seen in the parotid gland. There are single case reports mentioned in the literature. Clinical presentation is not characteristic and the disease is often overlooked with delay in diagnosis and treatment. We are reporting a case of bilateral parotid gland lymphoma in a 55-year-old male, presented with bilateral enlarged parotids. Magnetic resonance imaging (MRI) showed bilateral enlarged parotid glands with multiple well-defined intraparotid lesions. Fine Needle Aspiration Cytology (FNAC) of both showed mixed population of lymphoid cells with large monocytoid cells with scant cytoplasm, anisonucleosis with prominent nucleoli, and numerous mitoses suggestive of non-Hodgkin's lymphoma (NHL). Histopathology showed sheets of large lymphoma cells destructing the salivary acini and infiltrating the periparotid fat. Immunohistochemistry (IHC) showed diffuse CD20 positivity, B-cell lymphoma 6 protein (Bcl-6) was focally positive and negative for cluster of differentiation (CD) 3, CD5, CD10, and Multiple myeloma oncogene-1 (MUM1) which led to the diagnosis of NHL-Diffuse large B cell type.
journal_name
J Cytoljournal_title
Journal of cytologyauthors
Andola SK,Masgal MM,Reddy RMdoi
10.4103/0970-9371.190441subject
Has Abstractpub_date
2016-10-01 00:00:00pages
226-228issue
4eissn
0970-9371issn
0974-5165pii
JCytol-33-226journal_volume
33pub_type
abstract::Intravascular papillary endothelial hyperplasia (IVPEH) is an unusual form of intravascular endothelial proliferation. Fine needle aspiration (FNA) diagnosis of IVPEH is quite challenging and only rare reports of the cytopathological features of this entity have been published. We report a case of a 55-year-old female...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.107512
更新日期:2013-01-01 00:00:00
abstract::Hepatoblastoma (HBL) is a rare primary malignant liver tumor affecting mainly pediatric patients in the age group 6 months to 3 years. Presentation of HBL in the neonatal period is rare. HBL can be diagnosed on cytology along with subtyping. Estimation of serum alpha-fetoprotein (AFP) is essential as a tumor marker. F...
journal_title:Journal of cytology
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doi:10.4103/0970-9371.103945
更新日期:2012-10-01 00:00:00
abstract:Background:Cervical cancer is one of the most frequent malignancies in women. Micronucleus (MN) testing has gained popularity as a biomarker in early diagnosis of many types of cancer. Aims:This study aims to investigate the role of MN testing on early detection of cervical cancer and the effect of boron exposure on c...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_185_17
更新日期:2019-04-01 00:00:00
abstract::Castleman's disease (CD), also called giant lymph nodal hyperplasia, is a lymphoproliferative disorder secondary to lymphoid follicle hyperplasia and marked capillary proliferation with endothelial hyperplasia. It presents as enlarged lymph nodes in the mediastinum, neck, groin, axilla and other sites. On clinical exa...
journal_title:Journal of cytology
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doi:10.4103/0970-9371.73306
更新日期:2010-10-01 00:00:00
abstract::Rosai-Dorfman disease, that is, sinus histiocytosis with massive lymphadenopathy is a benign systemic proliferative disorder of histiocytes. The typical clinical presentation of the disease includes bilateral painless massive lymphadenopathy, fever and polyclonal hypergammaglobulinemia. Extranodal involvement is prese...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.83473
更新日期:2011-07-01 00:00:00
abstract::Xanthogranulomatous reaction can occur in any organ but the most common sites are kidney and gallbladder. Xanthogranulomatous appendicitis (XA) is a rare clinical entity. There are a few case reports of XA diagnosed on histopathology but none on cytology. Here we report a case of a 47-year-old lady who presented with ...
journal_title:Journal of cytology
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doi:10.4103/0970-9371.197619
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:Human immunodeficiency virus (HIV) infection has become a global pandemic. Persistent generalized lymphadenopathy (PGL) is very common manifestation of HIV infection. Moreover, different opportunistic infections such as tuberculosis (TB) and malignancies may present with lymphadenopathy. Mycobacterium aviu...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.182518
更新日期:2016-04-01 00:00:00
abstract:Background:Human papilloma virus (HPV) infection is the major etiologic agent of cervical carcinoma. The aim of this study was to determine the prevalence of HPV infection and genotype distribution in cervical swabs from 2,234 Turkish and 357 Albanian women with similar lifestyles from two different countries. Materia...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_162_17
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Cancer of the cervix has been considered as one of the preventable cancers. This study is the first published research addressing the screening of cancer of the cervix in the eastern region of Saudi Arabia. AIM:This study aims to detect the prevalence of abnormal epithelial changes and its types in the east...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.86343
更新日期:2011-10-01 00:00:00
abstract::Histoplasmosis is a mycotic infection caused by dimorphic fungus, Histoplasma capsulatum. The organisms are usually found within the cells (macrophages). This organism mostly affects lungs in immunocompetent individuals and disseminated forms are seen in immunocompromised cases. Here, we describe a case of disseminate...
journal_title:Journal of cytology
pub_type:
doi:10.4103/JOC.JOC_74_16
更新日期:2017-07-01 00:00:00
abstract:Introduction:The mortality due to uterine cervical cancer has been gradually increasing in women under 40 years of age (U40) in Japan. We investigated the effect of high-risk human papillomavirus (HR-HPV) on U40 subjects without any overt cytological abnormalities. Materials and Methods:We retrospectively examined the...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_148_17
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Fine needle aspiration cytology (FNAC) of oral and maxillofacial region has not been widely utilized for diagnosis due to diversity of lesion types, heterogeneity of cell populations and difficulties in reaching and aspirating these lesions. AIM:Our aim was to demonstrate the effectiveness of this cheap and...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.83461
更新日期:2011-07-01 00:00:00
abstract::Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) is a rare benign disease of unknown etiology presenting with massive lymphadenopathy. These cases can often be misdiagnosed as lymphoma. Hence, it is important to distinguish Rosai-Dorfman disease from lymphoma and other causes of histiocytosis b...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.55229
更新日期:2009-04-01 00:00:00
abstract::Gaucher's disease is the most common lysosomal storage disorder gene defect, which leads to deficiency or decreased activity of glucocerebrosidase, followed by accumulation of glucosylceramide. There is autosomal recessive transmission leading to varied clinical manifestations. This disease has three main types: Type ...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.59399
更新日期:2009-07-01 00:00:00
abstract::Primary lymphoma of the parotid gland is relatively rare and constitutes about 4-5% of extranodal lymphomas. The majority of them is non-Hodgkin lymphoma (NHL) and is B cell in nature. We report a case of primary diffuse large B-cell lymphoma (DLBCL) of the parotid gland in an elderly male. The case was diagnosed on f...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.182539
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:The role of DNA ploidy in genomic instability of cancer cells and prognosis has been described in a number of studies. The role of the centrosome in cell cycle has also been reported. AIM:In this study, we aimed to investigate the correlation between the centrosome and DNA ploidy in breast cancer in a searc...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.97150
更新日期:2012-04-01 00:00:00
abstract::Papillary thyroid carcinoma (PTC) is the most common malignant neoplasm of the thyroid. On fine-needle aspiration (FNA) cytology smears of conventional PTC, the background usually shows scanty, bubble gum-like colloid. But the macrofollicular variant and papillary microcarcinoma reveals abundant thin colloid in the ba...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.171252
更新日期:2015-10-01 00:00:00
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journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_135_18
更新日期:2019-04-01 00:00:00
abstract:AIM:To evaluate and compare the cytograding of breast cancers using Robinson's and Mouriquand's grading methods. MATERIALS AND METHODS:A 5-year retrospective (from Oct 2000 to Sept 2005) and 1-year prospective study (from Oct 2005 to Oct 2006). A total of 110 fine-needle aspiration cytology (FNAC) cases of breast canc...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.70738
更新日期:2010-04-01 00:00:00
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journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_94_17
更新日期:2018-01-01 00:00:00
abstract:Context:Intraoperative pathological assessment provides valuable information in a patient's diagnosis and management. Touch imprint/crush cytology is simple, rapid, and cost-effective. Also, imprint smears give excellent cytomorphology. Aims:To assess the utility and feasibility of intraoperative cytology technique as...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_94_19
更新日期:2020-07-01 00:00:00
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journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.93210
更新日期:2012-01-01 00:00:00
abstract::A case of lymphoepithelial carcinoma (LEC) occurring in right submandibular gland of a 13-year-old Indian male is presented, wherein the lesion unveiled itself only after multiple fine needle aspiration (FNA) procedures. This unusual neoplasm has high frequency of occurrence in Eskimos and a predilection for the parot...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.101185
更新日期:2012-07-01 00:00:00
abstract:BACKGROUND:Urine excreted by the body has a variable composition in different physiological and pathological conditions. The cells that come from the renal pelvis, ureters, bladder, and urethra are carried by the urine, and therefore, they can be observed in fresh samples and in smears with Giemsa and Papanicolaou stai...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.130666
更新日期:2014-01-01 00:00:00
abstract::Collagenous spherulosis is a rare entity usually seen in association with benign breast lesions. It is often picked up incidentally with a reported incidence of about 0.2% in cytological material. There are very few reports describing cytomorphological features of collagenous spherulosis. To the best of our knowledge ...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.138683
更新日期:2014-04-01 00:00:00
abstract::[This corrects the article on p. 153 in vol. 32, PMID: 26729974.]. ...
journal_title:Journal of cytology
pub_type: 已发布勘误
doi:10.4103/0970-9371.175533
更新日期:2016-01-01 00:00:00
abstract::There is only one report on cytological findings of oncocytic variant of chromophobe renal cell carcinoma (RCC). In this article, we report a new case with focus on cytological, and ultrastructural findings. A 60-year-old Japanese man was found to have a right renal tumor on medical checkup. In imprint cytological mat...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.168846
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Liquid-based cytology (LBC) preparation is a way to improve and refine the fine-needle aspiration (FNA) samples. There are a few studies comparing LBC with conventional smear (CS). AIM:The present study was undertaken to evaluate the utility of manual LBC (MLBC) and CS preparations in various FNA samples. ...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.190446
更新日期:2016-10-01 00:00:00
abstract:INTRODUCTION:Cervical intraepithelial neoplasia and cervical cancer remain important health problems. Cervical cytology by Papanicolaou (Pap) smears is an effective means of screening for cervical premalignant and malignant conditions. AIM:The aim of this study was to assess the prevalence of cervical dysplasia in pre...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.126659
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Image-guided fine-needle aspiration cytology (FNAC) serves as first-line diagnostic modalities for the assessment of mural thickening of the gallbladder (GB). AIM:The main objective of the present study was to correlate the diagnostic accuracy of preoperative image-guided FNAC of the thickened GB wall based...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.171231
更新日期:2015-10-01 00:00:00