Abstract:
BACKGROUND:Liquid-based cytology (LBC) preparation is a way to improve and refine the fine-needle aspiration (FNA) samples. There are a few studies comparing LBC with conventional smear (CS). AIM:The present study was undertaken to evaluate the utility of manual LBC (MLBC) and CS preparations in various FNA samples. MATERIALS AND METHODS:In this cross-sectional study, a total of 100 FNA samples from various anatomical sites were evaluated using MLBC and CS preparations. Cellularity, blood, informative background, monolayers, cell architecture, cytoplasmic, and nuclear preservation were compared with MLBC and CS preparations by Wilcoxon signed rank test. P < 0.05 is considered statistically significant. RESULTS:MLBC preparations were superior to CS preparations in view of absence of blood and debris (P = 0.001), presence of monolayers (P < 0.001), and preservation of cytoplasmic (P = 0.001) and nuclear details (P = 0.001). However, no statistically significant differences were found between MLBC and CS preparations with regard to cellularity (P = 0.157), informative background (P = 0.083), and architecture (P = 0.739). CONCLUSION:MLBC preparations in FNAC are a safe, easy, and less time-consuming procedure, and it may have promising diagnostic value in the evaluation of FNA samples from various anatomical sites. However, the use of both MLBC and CS preparations is recommended to achieve optimal diagnostic yield.
journal_name
J Cytoljournal_title
Journal of cytologyauthors
Arul Pdoi
10.4103/0970-9371.190446subject
Has Abstractpub_date
2016-10-01 00:00:00pages
177-181issue
4eissn
0970-9371issn
0974-5165pii
JCytol-33-177journal_volume
33pub_type
杂志文章abstract::The incidence of primary papillary carcinoma arising in thyroglossal cyst is rare and occurs in <1% of thyroglossal cysts. Even rarer is its diagnosis by pre-operative fine needle aspiration cytology (FNAC). Only 15 such cases diagnosed by FNAC have been previously reported in the literature. In this article, cytomorp...
journal_title:Journal of cytology
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doi:10.4103/0970-9371.66697
更新日期:2010-01-01 00:00:00
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journal_title:Journal of cytology
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doi:10.4103/0970-9371.107528
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journal_title:Journal of cytology
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journal_title:Journal of cytology
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更新日期:2012-10-01 00:00:00
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journal_title:Journal of cytology
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journal_title:Journal of cytology
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更新日期:2018-10-01 00:00:00
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更新日期:2012-01-01 00:00:00
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journal_title:Journal of cytology
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更新日期:2019-01-01 00:00:00
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journal_title:Journal of cytology
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更新日期:2014-10-01 00:00:00
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journal_title:Journal of cytology
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更新日期:2017-01-01 00:00:00
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journal_title:Journal of cytology
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更新日期:2011-04-01 00:00:00
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journal_title:Journal of cytology
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更新日期:2014-07-01 00:00:00
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更新日期:2010-04-01 00:00:00
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journal_title:Journal of cytology
pub_type:
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更新日期:2011-07-01 00:00:00
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journal_title:Journal of cytology
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doi:10.4103/0970-9371.107512
更新日期:2013-01-01 00:00:00
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journal_title:Journal of cytology
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pub_type:
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pub_type: 杂志文章
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更新日期:2019-04-01 00:00:00