Pleural effusion: Role of pleural fluid cytology, adenosine deaminase level, and pleural biopsy in diagnosis.

Abstract:

OBJECTIVE:The present study is designed to evaluate the role of pleural fluid analysis in diagnosing pleural diseases and to study the advantages and disadvantages of thoracocentasis and pleural biopsy. MATERIALS AND METHODS:We prospectively included 66 consecutive indoor patients over a duration of 1 year. Pleural fluid was collected and cytological smears were made from the fluid. Plural biopsy was done in the same patient by Cope needle. Adequate pleural biopsy tissue yielding specific diagnosis was obtained in 47 (71.2%) cases. RESULTS:Tuberculosis was the commonest nonneoplastic lesion followed by chronic nonspecific pleuritis comprising 60% and 33.3% of the nonneoplastic cases respectively and tuberculosis was predominantly diagnosed in the younger age group. Majority (70.8%) of malignancy cases were in the age group of >50-70. Adenocarcinoma was found to be the commonest (66.7%) malignant neoplasm in the pleurae followed by small-cell carcinoma (20.8%). CONCLUSION:Pleural biopsy is a useful and minimally invasive procedure. It is more sensitive and specific than pleural fluid smears.

journal_name

J Cytol

journal_title

Journal of cytology

authors

Biswas B,Sharma SK,Negi RS,Gupta N,Jaswal VM,Niranjan N

doi

10.4103/0970-9371.188062

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

159-162

issue

3

eissn

0970-9371

issn

0974-5165

pii

JCytol-33-159

journal_volume

33

pub_type

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