Abstract：
BACKGROUND:The cytological examinations of serous effusions have been well-accepted, and a positive diagnosis is often considered as a definitive diagnosis. It helps in staging, prognosis and management of the patients in malignancies and also gives information about various inflammatory and non-inflammatory lesions. Diagnostic problems arise in everyday practice to differentiate reactive atypical mesothelial cells and malignant cells by the routine conventional smear (CS) method. AIMS:To compare the morphological features of the CS method with those of the cell block (CB) method and also to assess the utility and sensitivity of the CB method in the cytodiagnosis of pleural effusions. MATERIALS AND METHODS:The study was conducted in the cytology section of the Department of Pathology. Sixty pleural fluid samples were subjected to diagnostic evaluation for over a period of 20 months. Along with the conventional smears, cell blocks were prepared by using 10% alcohol-formalin as a fixative agent. Statistical analysis with the 'z test' was performed to identify the cellularity, using the CS and CB methods. Mc. Naemer's χ(2)test was used to identify the additional yield for malignancy by the CB method. RESULTS:Cellularity and additional yield for malignancy was 15% more by the CB method. CONCLUSIONS:The CB method provides high cellularity, better architectural patterns, morphological features and an additional yield of malignant cells, and thereby, increases the sensitivity of the cytodiagnosis when compared with the CS method.
journal_name
J Cytoljournal_title
Journal of cytologyauthors
Shivakumarswamy U,Arakeri SU,Karigowdar MH,Yelikar Bdoi
10.4103/0970-9371.93210subject
Has Abstractpub_date
2012-01-01 00:00:00pages
11-5issue
1eissn
0970-9371issn
0974-5165pii
JCytol-29-11journal_volume
29pub_type
杂志文章abstract：:Primary splenic angiosarcoma is a rare malignant vascular neoplasm of mesenchymal origin. The tumor is highly aggressive and has a high metastatic potential. It is usually diagnosed on histopathological examination of splenectomy specimen. Only few cases of angiosarcoma diagnosed by fine-needle aspiration (FNA) cytolo...
journal_title：Journal of cytology
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doi：10.4103/JOC.JOC_148_16
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abstract：:Synovial sarcomas are rare tumors accounting for approximately 5-10% of soft tissue sarcomas. They occur predominantly in the extremities, followed by head and neck. Primary pulmonary sarcomas are very rare and comprise only 0.5% of all primary lung malignancies. The diagnosis is established only after sarcomas like p...
journal_title：Journal of cytology
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abstract：BACKGROUND:Fine needle aspiration cytology (FNAC) of oral and maxillofacial region has not been widely utilized for diagnosis due to diversity of lesion types, heterogeneity of cell populations and difficulties in reaching and aspirating these lesions. AIM:Our aim was to demonstrate the effectiveness of this cheap and...
journal_title：Journal of cytology
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journal_title：Journal of cytology
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doi：10.4103/0970-9371.182518
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journal_title：Journal of cytology
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doi：10.4103/0970-9371.107512
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:The role of DNA ploidy in genomic instability of cancer cells and prognosis has been described in a number of studies. The role of the centrosome in cell cycle has also been reported. AIM:In this study, we aimed to investigate the correlation between the centrosome and DNA ploidy in breast cancer in a searc...
journal_title：Journal of cytology
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journal_title：Journal of cytology
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journal_title：Journal of cytology
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更新日期：2014-04-01 00:00:00
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journal_title：Journal of cytology
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journal_title：Journal of cytology
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journal_title：Journal of cytology
pub_type： 杂志文章
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journal_title：Journal of cytology
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更新日期：2010-10-01 00:00:00
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journal_title：Journal of cytology
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journal_title：Journal of cytology
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journal_title：Journal of cytology
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更新日期：2011-01-01 00:00:00
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journal_title：Journal of cytology
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更新日期：2015-10-01 00:00:00
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journal_title：Journal of cytology
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journal_title：Journal of cytology
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更新日期：2011-10-01 00:00:00
abstract：Background:Cervical cancer is one of the most frequent malignancies in women. Micronucleus (MN) testing has gained popularity as a biomarker in early diagnosis of many types of cancer. Aims:This study aims to investigate the role of MN testing on early detection of cervical cancer and the effect of boron exposure on c...
journal_title：Journal of cytology
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journal_title：Journal of cytology
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journal_title：Journal of cytology
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journal_title：Journal of cytology
pub_type：
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更新日期：2011-07-01 00:00:00
abstract：:[This corrects the article on p. 153 in vol. 32, PMID: 26729974.]. ...
journal_title：Journal of cytology
pub_type： 已发布勘误
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journal_title：Journal of cytology
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更新日期：2014-07-01 00:00:00
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journal_title：Journal of cytology
pub_type： 杂志文章
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journal_title：Journal of cytology
pub_type：
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journal_title：Journal of cytology
pub_type：
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更新日期：2012-07-01 00:00:00
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journal_title：Journal of cytology
pub_type： 杂志文章
doi：10.4103/0970-9371.80745
更新日期：2011-04-01 00:00:00
