Abstract:
:A case of lymphoepithelial carcinoma (LEC) occurring in right submandibular gland of a 13-year-old Indian male is presented, wherein the lesion unveiled itself only after multiple fine needle aspiration (FNA) procedures. This unusual neoplasm has high frequency of occurrence in Eskimos and a predilection for the parotid gland. The aspirates obtained were highly cellular comprising tight clusters of atypical epithelial cells with admixture of lymphocytes. Histopathological examination of the resected submandibular gland and lymph node chain was consistent with the diagnosis of LEC. Immunohistochemistry (IHC) revealed cytokeratin (CK)-positive and S-100-negative tumor cells lying admixed with CD45-positive lymphoid cells. A detailed otorhinolaryngological examination with inclusion of multiple biopsies was found negative for any primary tumor. Although histopathological features of this entity are well established, only a handful of case reports describing cytological features of this entity are present in medical literature. We conclude that the cytomorphological features of LEC are sufficiently distinctive to at least, suggest a possibility of this lesion.
journal_name
J Cytoljournal_title
Journal of cytologyauthors
Amit S,Agarwal A,Khan Ldoi
10.4103/0970-9371.101185subject
Has Abstractpub_date
2012-07-01 00:00:00pages
216-8issue
3eissn
0970-9371issn
0974-5165pii
JCytol-29-216journal_volume
29pub_type
abstract::Chondroid syringoma is a rare benign adnexal tumor of sweat glands with microscopic resemblance to the salivary gland pleomorphic adenoma. Cytology is rarely utilized for preoperative assessment of these slow-growing, small, nodular lesions. Definitive cytological diagnosis is also quite difficult, and majority of the...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.145659
更新日期:2014-07-01 00:00:00
abstract::Histoplasmosis is a mycotic infection caused by dimorphic fungus, Histoplasma capsulatum. The organisms are usually found within the cells (macrophages). This organism mostly affects lungs in immunocompetent individuals and disseminated forms are seen in immunocompromised cases. Here, we describe a case of disseminate...
journal_title:Journal of cytology
pub_type:
doi:10.4103/JOC.JOC_74_16
更新日期:2017-07-01 00:00:00
abstract::There is only one report on cytological findings of oncocytic variant of chromophobe renal cell carcinoma (RCC). In this article, we report a new case with focus on cytological, and ultrastructural findings. A 60-year-old Japanese man was found to have a right renal tumor on medical checkup. In imprint cytological mat...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.168846
更新日期:2015-07-01 00:00:00
abstract::Lung cancer (LC) is the leading cause of cancer-related mortality. Unfortunately, most patients of LC present at the advanced stage of the disease with a poor prognosis and 1-year survival of less than 20%. At the advanced stage of the disease, surgical resection cannot be possible, hence small biopsy or cytology spec...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_135_18
更新日期:2019-04-01 00:00:00
abstract:Introduction:The mortality due to uterine cervical cancer has been gradually increasing in women under 40 years of age (U40) in Japan. We investigated the effect of high-risk human papillomavirus (HR-HPV) on U40 subjects without any overt cytological abnormalities. Materials and Methods:We retrospectively examined the...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_148_17
更新日期:2019-07-01 00:00:00
abstract:Background:Micronucleus (MN) is an extranuclear body within the cell formed due to failure of incorporation of whole chromosomes or their fragments during cell division. MN scoring can be done to identify malignant effusions. Aims:This study aimed to score micronuclei to distinguish malignant effusion from benign effu...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_42_19
更新日期:2020-01-01 00:00:00
abstract::Xanthogranulomatous reaction can occur in any organ but the most common sites are kidney and gallbladder. Xanthogranulomatous appendicitis (XA) is a rare clinical entity. There are a few case reports of XA diagnosed on histopathology but none on cytology. Here we report a case of a 47-year-old lady who presented with ...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.197619
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Oral lichen planus (OLP) is one of the potentially malignant disorders (PMDs) with a malignancy rate of 0.2-2%. Aneuploidy is considered to be one of the important markers for malignant transformation and DNA-image cytometry (DIC) has been successfully employed in oral mucosal PMDs and also in tumors of the ...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.145629
更新日期:2014-07-01 00:00:00
abstract::Papillary thyroid carcinoma (PTC) is the most common malignant neoplasm of the thyroid. On fine-needle aspiration (FNA) cytology smears of conventional PTC, the background usually shows scanty, bubble gum-like colloid. But the macrofollicular variant and papillary microcarcinoma reveals abundant thin colloid in the ba...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.171252
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:The role of DNA ploidy in genomic instability of cancer cells and prognosis has been described in a number of studies. The role of the centrosome in cell cycle has also been reported. AIM:In this study, we aimed to investigate the correlation between the centrosome and DNA ploidy in breast cancer in a searc...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.97150
更新日期:2012-04-01 00:00:00
abstract::Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) is a rare benign disease of unknown etiology presenting with massive lymphadenopathy. These cases can often be misdiagnosed as lymphoma. Hence, it is important to distinguish Rosai-Dorfman disease from lymphoma and other causes of histiocytosis b...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.55229
更新日期:2009-04-01 00:00:00
abstract::Herpes simplex virus (HSV) is a rare cause of breast infection. Few cases of maternal-infant transmission of the virus during breastfeeding resulting in nipple lesions have been documented. Only three cases have been reported in nonlactating women. We report an additional case of HSV mastitis in a 36-year-old nonlacta...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.62185
更新日期:2009-10-01 00:00:00
abstract:Background:Skin adnexal neoplasms are relatively rare and thus uncommonly encountered in routine pathology practice. Aims:The present study was conducted with the aim to diagnose various skin adnexal tumors on fine-needle aspiration cytology (FNAC) followed by confirmation on histopathology and immunohistochemistry of...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_63_17
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:The cytological examinations of serous effusions have been well-accepted, and a positive diagnosis is often considered as a definitive diagnosis. It helps in staging, prognosis and management of the patients in malignancies and also gives information about various inflammatory and non-inflammatory lesions. D...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.93210
更新日期:2012-01-01 00:00:00
abstract::The incidence of primary papillary carcinoma arising in thyroglossal cyst is rare and occurs in <1% of thyroglossal cysts. Even rarer is its diagnosis by pre-operative fine needle aspiration cytology (FNAC). Only 15 such cases diagnosed by FNAC have been previously reported in the literature. In this article, cytomorp...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.66697
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Liquid-based cytology (LBC) preparation is a way to improve and refine the fine-needle aspiration (FNA) samples. There are a few studies comparing LBC with conventional smear (CS). AIM:The present study was undertaken to evaluate the utility of manual LBC (MLBC) and CS preparations in various FNA samples. ...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.190446
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Image-guided fine-needle aspiration cytology (FNAC) serves as first-line diagnostic modalities for the assessment of mural thickening of the gallbladder (GB). AIM:The main objective of the present study was to correlate the diagnostic accuracy of preoperative image-guided FNAC of the thickened GB wall based...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.171231
更新日期:2015-10-01 00:00:00
abstract::Rosai-Dorfman disease, that is, sinus histiocytosis with massive lymphadenopathy is a benign systemic proliferative disorder of histiocytes. The typical clinical presentation of the disease includes bilateral painless massive lymphadenopathy, fever and polyclonal hypergammaglobulinemia. Extranodal involvement is prese...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.83473
更新日期:2011-07-01 00:00:00
abstract::Prostatic adenocarcinoma (PA) is a common visceral malignancy of elderly men. Cutaneous metastasis of PA is rare. The incidence is <1%. A 55-year-old man presented with urinary symptoms and multiple cutaneous nodules around suprapubic region, inner aspect of both thighs and scrotum. Fine-needle aspiration cytology (FN...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.160568
更新日期:2015-04-01 00:00:00
abstract:Context:Intraoperative pathological assessment provides valuable information in a patient's diagnosis and management. Touch imprint/crush cytology is simple, rapid, and cost-effective. Also, imprint smears give excellent cytomorphology. Aims:To assess the utility and feasibility of intraoperative cytology technique as...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_94_19
更新日期:2020-07-01 00:00:00
abstract:Aims:Tzanck smear is an old but useful test for diagnosis of cutaneous dermatoses. The aim of this study was to highlight the potential usefulness and diagnostic pitfalls of Tzanck smear for diagnosis of cutaneous dermatoses and infections. Materials and Methods:This hospital based cross-sectional study was carried ou...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_88_16
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:It has been shown that cigarette smoking as well as diabetes mellitus can produce cytomorphometric alterations in oral epithelial cells with the significant increase in the nuclear area (NA) and significant decrease in the cytoplasmic/nuclear ratio in comparison to healthy control. However, the synergistic e...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.112653
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:Fine needle aspiration cytology (FNAC) of oral and maxillofacial region has not been widely utilized for diagnosis due to diversity of lesion types, heterogeneity of cell populations and difficulties in reaching and aspirating these lesions. AIM:Our aim was to demonstrate the effectiveness of this cheap and...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.83461
更新日期:2011-07-01 00:00:00
abstract::Adult-type granulosa cell tumors (AGCT) account for 1-2% of all ovarian tumors and 95% of granulosa cell tumors. In AGCT, at the time of peritoneal washing, tumor cells are rarely seen to exfoliate and FIGO stage is raised from IA/IB or IIA/IIB to stage IC or IIC despite the absence of a gross intraepithelial tumor. P...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.107528
更新日期:2013-01-01 00:00:00
abstract::Synovial sarcomas are rare tumors accounting for approximately 5-10% of soft tissue sarcomas. They occur predominantly in the extremities, followed by head and neck. Primary pulmonary sarcomas are very rare and comprise only 0.5% of all primary lung malignancies. The diagnosis is established only after sarcomas like p...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.155240
更新日期:2015-01-01 00:00:00
abstract:Background:Human papilloma virus (HPV) infection is the major etiologic agent of cervical carcinoma. The aim of this study was to determine the prevalence of HPV infection and genotype distribution in cervical swabs from 2,234 Turkish and 357 Albanian women with similar lifestyles from two different countries. Materia...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_162_17
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Micronuclei in exfoliated oral epithelial cells have been shown in some studies to correlate with severity of this genotoxic damage. This severity can be measured in terms of grading of the lesions. AIM:To correlate frequency of micronuclei (MN) in oral exfoliated cells in clinically diagnosed cases of oral...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.76941
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Urine excreted by the body has a variable composition in different physiological and pathological conditions. The cells that come from the renal pelvis, ureters, bladder, and urethra are carried by the urine, and therefore, they can be observed in fresh samples and in smears with Giemsa and Papanicolaou stai...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.130666
更新日期:2014-01-01 00:00:00
abstract:AIM:To evaluate and compare the cytograding of breast cancers using Robinson's and Mouriquand's grading methods. MATERIALS AND METHODS:A 5-year retrospective (from Oct 2000 to Sept 2005) and 1-year prospective study (from Oct 2005 to Oct 2006). A total of 110 fine-needle aspiration cytology (FNAC) cases of breast canc...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.70738
更新日期:2010-04-01 00:00:00
abstract::Extra-abdominal desmoid tumors are known as aggressive fibromatosis (AFM). Synchronous and metachronous multicentric aggressive fibromatosis are rare lesions and pose dilemma in diagnosis and management. A rare and interesting case of recurrent multicentric, synchronous AFM is presented which to the best of our knowle...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.93227
更新日期:2012-01-01 00:00:00