Abstract:
Background:Micronucleus (MN) is an extranuclear body within the cell formed due to failure of incorporation of whole chromosomes or their fragments during cell division. MN scoring can be done to identify malignant effusions. Aims:This study aimed to score micronuclei to distinguish malignant effusion from benign effusions and to correlate MN score with type of malignant effusion. Methods and Materials:A retrospective study was conducted on 30 malignant and 30 benign effusions. The number of micronucleated cells per 1,000 cells was counted in effusion smears stained with Papanicolaou stain under oil immersion (1,000×). Results:The mean MN score in malignant effusions was 3.77 with standard deviation (SD) of 2.13. The mean MN score in benign effusions was 0.50 with SD of 0.57. The difference in MN score between malignant and benign effusions is statistically significant (P < 0.001). A cut-off MN score of 6.5 was seen to distinguish malignant and benign effusions with 100% specificity and 100% sensitivity in this study. Conclusions:MN score is higher in malignant effusions when compared with benign effusions. This can be used to differentiate malignant effusions from benign effusions in low resource setting.
journal_name
J Cytoljournal_title
Journal of cytologyauthors
Jayakumar D,Kasturi KKdoi
10.4103/JOC.JOC_42_19subject
Has Abstractpub_date
2020-01-01 00:00:00pages
58-61issue
1eissn
0970-9371issn
0974-5165pii
JCytol-37-58journal_volume
37pub_type
杂志文章abstract::Papillary thyroid carcinoma (PTC) is the most common malignant neoplasm of the thyroid. On fine-needle aspiration (FNA) cytology smears of conventional PTC, the background usually shows scanty, bubble gum-like colloid. But the macrofollicular variant and papillary microcarcinoma reveals abundant thin colloid in the ba...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.171252
更新日期:2015-10-01 00:00:00
abstract::There is only one report on cytological findings of oncocytic variant of chromophobe renal cell carcinoma (RCC). In this article, we report a new case with focus on cytological, and ultrastructural findings. A 60-year-old Japanese man was found to have a right renal tumor on medical checkup. In imprint cytological mat...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.168846
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:It is now known that the disease process of diabetes has effects on various tissues of the body. The following study was done to analyze the effects of diabetes on oral tissues. AIMS:To study the morphology and cytomorphometry of the cells obtained in cytologic smears from the buccal mucosa of diabetic pati...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.73291
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:Liquid-based cytology (LBC) preparation is a way to improve and refine the fine-needle aspiration (FNA) samples. There are a few studies comparing LBC with conventional smear (CS). AIM:The present study was undertaken to evaluate the utility of manual LBC (MLBC) and CS preparations in various FNA samples. ...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.190446
更新日期:2016-10-01 00:00:00
abstract:AIM:Surgical pathology service is generally unavailable in most developing countries and comes with challenges. Cytopathology is a reliable, inexpensive adjunct to surgical histopathology. We present a retrospective review of the various cytopathology cases received at the department. MATERIALS AND METHODS:A retrospec...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.197593
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:The cytological examinations of serous effusions have been well-accepted, and a positive diagnosis is often considered as a definitive diagnosis. It helps in staging, prognosis and management of the patients in malignancies and also gives information about various inflammatory and non-inflammatory lesions. D...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.93210
更新日期:2012-01-01 00:00:00
abstract:Background:Skin adnexal neoplasms are relatively rare and thus uncommonly encountered in routine pathology practice. Aims:The present study was conducted with the aim to diagnose various skin adnexal tumors on fine-needle aspiration cytology (FNAC) followed by confirmation on histopathology and immunohistochemistry of...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_63_17
更新日期:2018-10-01 00:00:00
abstract::Intravascular papillary endothelial hyperplasia (IVPEH) is an unusual form of intravascular endothelial proliferation. Fine needle aspiration (FNA) diagnosis of IVPEH is quite challenging and only rare reports of the cytopathological features of this entity have been published. We report a case of a 55-year-old female...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.107512
更新日期:2013-01-01 00:00:00
abstract::Adult-type granulosa cell tumors (AGCT) account for 1-2% of all ovarian tumors and 95% of granulosa cell tumors. In AGCT, at the time of peritoneal washing, tumor cells are rarely seen to exfoliate and FIGO stage is raised from IA/IB or IIA/IIB to stage IC or IIC despite the absence of a gross intraepithelial tumor. P...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.107528
更新日期:2013-01-01 00:00:00
abstract::Extra-abdominal desmoid tumors are known as aggressive fibromatosis (AFM). Synchronous and metachronous multicentric aggressive fibromatosis are rare lesions and pose dilemma in diagnosis and management. A rare and interesting case of recurrent multicentric, synchronous AFM is presented which to the best of our knowle...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.93227
更新日期:2012-01-01 00:00:00
abstract::In this paper, we have described fine needle aspiration cytology (FNAC) of a rare case of dermal cylindroma. A 40-year-old female presented with a lateral mid-cervical swelling fixed to the skin. FNAC smears showed multiple clusters of small, round to oval cells with hyperchromatic nuclei, inconspicuous nucleoli and s...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.151137
更新日期:2014-10-01 00:00:00
abstract::Xanthogranulomatous reaction can occur in any organ but the most common sites are kidney and gallbladder. Xanthogranulomatous appendicitis (XA) is a rare clinical entity. There are a few case reports of XA diagnosed on histopathology but none on cytology. Here we report a case of a 47-year-old lady who presented with ...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.197619
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Micronuclei in exfoliated oral epithelial cells have been shown in some studies to correlate with severity of this genotoxic damage. This severity can be measured in terms of grading of the lesions. AIM:To correlate frequency of micronuclei (MN) in oral exfoliated cells in clinically diagnosed cases of oral...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.76941
更新日期:2011-01-01 00:00:00
abstract:AIM:To evaluate and compare the cytograding of breast cancers using Robinson's and Mouriquand's grading methods. MATERIALS AND METHODS:A 5-year retrospective (from Oct 2000 to Sept 2005) and 1-year prospective study (from Oct 2005 to Oct 2006). A total of 110 fine-needle aspiration cytology (FNAC) cases of breast canc...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.70738
更新日期:2010-04-01 00:00:00
abstract::Primary (spontaneous) umbilical endometriosis is very rare with an estimated incidence of 0.5-1% of all patients with endometrial ectopia. Endometriosis is a common gynecological condition, the pelvis being the most common site of the disease. Extrapelvic site is less common and even more difficult to diagnose due to ...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.86355
更新日期:2011-10-01 00:00:00
abstract::Salivary gland cytopathology is a diagnostically challenging area with overlapping cytomorphological features between benign, malignant, and metastatic tumors. We report the case of 45-year-old male who presented with two swellings in right retroauricular and infraauricular region along with a palpable single right ce...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.203576
更新日期:2017-04-01 00:00:00
abstract::Hepatoblastoma (HBL) is a rare primary malignant liver tumor affecting mainly pediatric patients in the age group 6 months to 3 years. Presentation of HBL in the neonatal period is rare. HBL can be diagnosed on cytology along with subtyping. Estimation of serum alpha-fetoprotein (AFP) is essential as a tumor marker. F...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.103945
更新日期:2012-10-01 00:00:00
abstract:Aims:Tzanck smear is an old but useful test for diagnosis of cutaneous dermatoses. The aim of this study was to highlight the potential usefulness and diagnostic pitfalls of Tzanck smear for diagnosis of cutaneous dermatoses and infections. Materials and Methods:This hospital based cross-sectional study was carried ou...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_88_16
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Cancer of the cervix has been considered as one of the preventable cancers. This study is the first published research addressing the screening of cancer of the cervix in the eastern region of Saudi Arabia. AIM:This study aims to detect the prevalence of abnormal epithelial changes and its types in the east...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.86343
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:The use of oral exfoliative cytology as a diagnostic aid accentuates the need for establishing an accurate baseline, thereby enabling the comparison of abnormal oral tissue with established baseline. AIMS AND OBJECTIVE:To detect any changes in the nuclear area (NA), cytoplasmic area (CA), and nuclear:cytopl...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.80745
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Neuropathology centers are expected to offer a prompt and accurate intraoperative diagnosis regarding tumor/lesion type and grade on fresh unfixed tissue. Level of diagnostic accuracy according to type and grade and also, the experience at a new center has not been reported before. AIMS:The aim of this stud...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.117677
更新日期:2013-07-01 00:00:00
abstract:Context:Fine needle aspiration (FNA) plays a crucial role in the evaluation of patients with thyroid lesions. The Bethesda system for reporting thyroid cytopathology (TBSRTC) was designed with a mission to standardize the process of diagnosis and management of thyroid lesions by FNA cytology (FNAC). Aim:We aim to see ...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_64_18
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:It has been shown that cigarette smoking as well as diabetes mellitus can produce cytomorphometric alterations in oral epithelial cells with the significant increase in the nuclear area (NA) and significant decrease in the cytoplasmic/nuclear ratio in comparison to healthy control. However, the synergistic e...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.112653
更新日期:2013-04-01 00:00:00
abstract::Chondroid syringoma is a rare benign adnexal tumor of sweat glands with microscopic resemblance to the salivary gland pleomorphic adenoma. Cytology is rarely utilized for preoperative assessment of these slow-growing, small, nodular lesions. Definitive cytological diagnosis is also quite difficult, and majority of the...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.145659
更新日期:2014-07-01 00:00:00
abstract::Tuberculosis of cervix is a rare disease. Tuberculosis usually affects women of childbearing age, indicating hormone dependence of infection. The patient presents with menstrual irregularities, infertility or vaginal discharge. Cervical lesions presents as papillary/vegetative growth or ulceration mimicking cervical c...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.93242
更新日期:2012-01-01 00:00:00
abstract::Rosai-Dorfman disease, that is, sinus histiocytosis with massive lymphadenopathy is a benign systemic proliferative disorder of histiocytes. The typical clinical presentation of the disease includes bilateral painless massive lymphadenopathy, fever and polyclonal hypergammaglobulinemia. Extranodal involvement is prese...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.83473
更新日期:2011-07-01 00:00:00
abstract::Malignant mesothelioma of pleura is a locally aggressive rare neoplasm of mesothelial cells, which produces distant metastasis in advanced stages of its course. It is exceptional for patients to present with metastasis prior to the detection of primary tumor in the pleura. Here, we report a case of malignant mesotheli...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.216123
更新日期:2017-10-01 00:00:00
abstract::Collagenous spherulosis is a rare entity usually seen in association with benign breast lesions. It is often picked up incidentally with a reported incidence of about 0.2% in cytological material. There are very few reports describing cytomorphological features of collagenous spherulosis. To the best of our knowledge ...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.138683
更新日期:2014-04-01 00:00:00
abstract::Gaucher's disease is the most common lysosomal storage disorder gene defect, which leads to deficiency or decreased activity of glucocerebrosidase, followed by accumulation of glucosylceramide. There is autosomal recessive transmission leading to varied clinical manifestations. This disease has three main types: Type ...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.59399
更新日期:2009-07-01 00:00:00
abstract::Prostatic adenocarcinoma (PA) is a common visceral malignancy of elderly men. Cutaneous metastasis of PA is rare. The incidence is <1%. A 55-year-old man presented with urinary symptoms and multiple cutaneous nodules around suprapubic region, inner aspect of both thighs and scrotum. Fine-needle aspiration cytology (FN...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.160568
更新日期:2015-04-01 00:00:00