Abstract:
:Gaucher's disease is the most common lysosomal storage disorder gene defect, which leads to deficiency or decreased activity of glucocerebrosidase, followed by accumulation of glucosylceramide. There is autosomal recessive transmission leading to varied clinical manifestations. This disease has three main types: Type I - nonneuronopathic; type II - acute neuronopathic; and type III - chronic neuronopathic. The nonneuronopathic type has the highest prevalence and also the greatest variability. The authors here report two cases of Gaucher's disease with uncommon presentations in early childhood, highlighting the importance of early diagnosis of the disease, as now-a-days enzyme replacement therapy may arrest further progress of disease.
journal_name
J Cytoljournal_title
Journal of cytologyauthors
Gupta SS,Mondal P,Basu N,Mallick MGdoi
10.4103/0970-9371.59399subject
Has Abstractpub_date
2009-07-01 00:00:00pages
117-9issue
3eissn
0970-9371issn
0974-5165pii
JCytol-26-117journal_volume
26pub_type
abstract:BACKGROUND:Neuropathology centers are expected to offer a prompt and accurate intraoperative diagnosis regarding tumor/lesion type and grade on fresh unfixed tissue. Level of diagnostic accuracy according to type and grade and also, the experience at a new center has not been reported before. AIMS:The aim of this stud...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.117677
更新日期:2013-07-01 00:00:00
abstract::Chondroid syringoma is a rare benign adnexal tumor of sweat glands with microscopic resemblance to the salivary gland pleomorphic adenoma. Cytology is rarely utilized for preoperative assessment of these slow-growing, small, nodular lesions. Definitive cytological diagnosis is also quite difficult, and majority of the...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.145659
更新日期:2014-07-01 00:00:00
abstract:AIM:To evaluate and compare the cytograding of breast cancers using Robinson's and Mouriquand's grading methods. MATERIALS AND METHODS:A 5-year retrospective (from Oct 2000 to Sept 2005) and 1-year prospective study (from Oct 2005 to Oct 2006). A total of 110 fine-needle aspiration cytology (FNAC) cases of breast canc...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.70738
更新日期:2010-04-01 00:00:00
abstract::Extra-abdominal desmoid tumors are known as aggressive fibromatosis (AFM). Synchronous and metachronous multicentric aggressive fibromatosis are rare lesions and pose dilemma in diagnosis and management. A rare and interesting case of recurrent multicentric, synchronous AFM is presented which to the best of our knowle...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.93227
更新日期:2012-01-01 00:00:00
abstract::Salivary gland cytopathology is a diagnostically challenging area with overlapping cytomorphological features between benign, malignant, and metastatic tumors. We report the case of 45-year-old male who presented with two swellings in right retroauricular and infraauricular region along with a palpable single right ce...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.203576
更新日期:2017-04-01 00:00:00
abstract::Tissue diagnosis of small round cell tumors relies heavily on immunohistochemical staining. Two of the small round cell tumors, namely neuroblastoma and primitive neuroectodermal tumor, have considerable morphologic overlap. Many studies suggest that CD99 positivity virtually excludes the diagnosis of neuroblastoma. W...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.97162
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:The cytological examinations of serous effusions have been well-accepted, and a positive diagnosis is often considered as a definitive diagnosis. It helps in staging, prognosis and management of the patients in malignancies and also gives information about various inflammatory and non-inflammatory lesions. D...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.93210
更新日期:2012-01-01 00:00:00
abstract::In this paper, we have described fine needle aspiration cytology (FNAC) of a rare case of dermal cylindroma. A 40-year-old female presented with a lateral mid-cervical swelling fixed to the skin. FNAC smears showed multiple clusters of small, round to oval cells with hyperchromatic nuclei, inconspicuous nucleoli and s...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.151137
更新日期:2014-10-01 00:00:00
abstract::Collagenous spherulosis is a rare entity usually seen in association with benign breast lesions. It is often picked up incidentally with a reported incidence of about 0.2% in cytological material. There are very few reports describing cytomorphological features of collagenous spherulosis. To the best of our knowledge ...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.138683
更新日期:2014-04-01 00:00:00
abstract:Background:Skin adnexal neoplasms are relatively rare and thus uncommonly encountered in routine pathology practice. Aims:The present study was conducted with the aim to diagnose various skin adnexal tumors on fine-needle aspiration cytology (FNAC) followed by confirmation on histopathology and immunohistochemistry of...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_63_17
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Urine excreted by the body has a variable composition in different physiological and pathological conditions. The cells that come from the renal pelvis, ureters, bladder, and urethra are carried by the urine, and therefore, they can be observed in fresh samples and in smears with Giemsa and Papanicolaou stai...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.130666
更新日期:2014-01-01 00:00:00
abstract:Aims:Tzanck smear is an old but useful test for diagnosis of cutaneous dermatoses. The aim of this study was to highlight the potential usefulness and diagnostic pitfalls of Tzanck smear for diagnosis of cutaneous dermatoses and infections. Materials and Methods:This hospital based cross-sectional study was carried ou...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_88_16
更新日期:2017-10-01 00:00:00
abstract::Histoplasmosis is a mycotic infection caused by dimorphic fungus, Histoplasma capsulatum. The organisms are usually found within the cells (macrophages). This organism mostly affects lungs in immunocompetent individuals and disseminated forms are seen in immunocompromised cases. Here, we describe a case of disseminate...
journal_title:Journal of cytology
pub_type:
doi:10.4103/JOC.JOC_74_16
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVE:The present study is designed to evaluate the role of pleural fluid analysis in diagnosing pleural diseases and to study the advantages and disadvantages of thoracocentasis and pleural biopsy. MATERIALS AND METHODS:We prospectively included 66 consecutive indoor patients over a duration of 1 year. Pleural fl...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.188062
更新日期:2016-07-01 00:00:00
abstract::Fibromatosis colli is a peculiar, benign fibrous growth of the sternocleidomastoid that usually appears during the first few weeks of life and is often associated with muscular torticollis. Fibromatosis colli (FC) is seen in children born after difficult, prolonged labor, assisted delivery, and breech deliveries. Clin...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.54869
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Oral lichen planus (OLP) is one of the potentially malignant disorders (PMDs) with a malignancy rate of 0.2-2%. Aneuploidy is considered to be one of the important markers for malignant transformation and DNA-image cytometry (DIC) has been successfully employed in oral mucosal PMDs and also in tumors of the ...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.145629
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:Liquid-based cytology (LBC) preparation is a way to improve and refine the fine-needle aspiration (FNA) samples. There are a few studies comparing LBC with conventional smear (CS). AIM:The present study was undertaken to evaluate the utility of manual LBC (MLBC) and CS preparations in various FNA samples. ...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.190446
更新日期:2016-10-01 00:00:00
abstract::Malignant mesothelioma of pleura is a locally aggressive rare neoplasm of mesothelial cells, which produces distant metastasis in advanced stages of its course. It is exceptional for patients to present with metastasis prior to the detection of primary tumor in the pleura. Here, we report a case of malignant mesotheli...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.216123
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:The role of DNA ploidy in genomic instability of cancer cells and prognosis has been described in a number of studies. The role of the centrosome in cell cycle has also been reported. AIM:In this study, we aimed to investigate the correlation between the centrosome and DNA ploidy in breast cancer in a searc...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.97150
更新日期:2012-04-01 00:00:00
abstract:AIM:Surgical pathology service is generally unavailable in most developing countries and comes with challenges. Cytopathology is a reliable, inexpensive adjunct to surgical histopathology. We present a retrospective review of the various cytopathology cases received at the department. MATERIALS AND METHODS:A retrospec...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.197593
更新日期:2017-01-01 00:00:00
abstract::Primary lymphoma of the parotid gland is relatively rare and constitutes about 4-5% of extranodal lymphomas. The majority of them is non-Hodgkin lymphoma (NHL) and is B cell in nature. We report a case of primary diffuse large B-cell lymphoma (DLBCL) of the parotid gland in an elderly male. The case was diagnosed on f...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.182539
更新日期:2016-04-01 00:00:00
abstract::Preoperative pathologic diagnosis of pelvic tumors is mandatory for proper management of patients like neoadjuvant chemotherapy and interval debulking. Currently there are many minimally invasive methods available which include fine-needle aspiration cytology (FNAC) and trucut biopsy, mostly complimentary to each othe...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_63_18
更新日期:2018-07-01 00:00:00
abstract::Herpes simplex virus (HSV) is a rare cause of breast infection. Few cases of maternal-infant transmission of the virus during breastfeeding resulting in nipple lesions have been documented. Only three cases have been reported in nonlactating women. We report an additional case of HSV mastitis in a 36-year-old nonlacta...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.62185
更新日期:2009-10-01 00:00:00
abstract::Prostatic adenocarcinoma (PA) is a common visceral malignancy of elderly men. Cutaneous metastasis of PA is rare. The incidence is <1%. A 55-year-old man presented with urinary symptoms and multiple cutaneous nodules around suprapubic region, inner aspect of both thighs and scrotum. Fine-needle aspiration cytology (FN...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.160568
更新日期:2015-04-01 00:00:00
abstract:Context:Fine needle aspiration (FNA) plays a crucial role in the evaluation of patients with thyroid lesions. The Bethesda system for reporting thyroid cytopathology (TBSRTC) was designed with a mission to standardize the process of diagnosis and management of thyroid lesions by FNA cytology (FNAC). Aim:We aim to see ...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_64_18
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:It has been shown that cigarette smoking as well as diabetes mellitus can produce cytomorphometric alterations in oral epithelial cells with the significant increase in the nuclear area (NA) and significant decrease in the cytoplasmic/nuclear ratio in comparison to healthy control. However, the synergistic e...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.112653
更新日期:2013-04-01 00:00:00
abstract:Background:Micronucleus (MN) is an extranuclear body within the cell formed due to failure of incorporation of whole chromosomes or their fragments during cell division. MN scoring can be done to identify malignant effusions. Aims:This study aimed to score micronuclei to distinguish malignant effusion from benign effu...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_42_19
更新日期:2020-01-01 00:00:00
abstract:Context:Intraoperative pathological assessment provides valuable information in a patient's diagnosis and management. Touch imprint/crush cytology is simple, rapid, and cost-effective. Also, imprint smears give excellent cytomorphology. Aims:To assess the utility and feasibility of intraoperative cytology technique as...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_94_19
更新日期:2020-07-01 00:00:00
abstract::The incidence of primary papillary carcinoma arising in thyroglossal cyst is rare and occurs in <1% of thyroglossal cysts. Even rarer is its diagnosis by pre-operative fine needle aspiration cytology (FNAC). Only 15 such cases diagnosed by FNAC have been previously reported in the literature. In this article, cytomorp...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.66697
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:The use of oral exfoliative cytology as a diagnostic aid accentuates the need for establishing an accurate baseline, thereby enabling the comparison of abnormal oral tissue with established baseline. AIMS AND OBJECTIVE:To detect any changes in the nuclear area (NA), cytoplasmic area (CA), and nuclear:cytopl...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.80745
更新日期:2011-04-01 00:00:00