Abstract:
Aims:Tzanck smear is an old but useful test for diagnosis of cutaneous dermatoses. The aim of this study was to highlight the potential usefulness and diagnostic pitfalls of Tzanck smear for diagnosis of cutaneous dermatoses and infections. Materials and Methods:This hospital based cross-sectional study was carried out on all Tzanck smears received for a period of twenty months (January 2014-August 2015). The smears were assessed to establish the utility of Tzanck smears in corroborating or excluding a diagnosis of immunobullous lesion or herpetic infection. Cases with discrepant diagnosis on histopathology were reviewed to identify additional cytomorphological features. Results:A total of 57 Tzanck smears were performed during the study period. Out of the 18 clinically suspected cases of immunobullous disorders, Tzanck smear findings corroborated the clinical diagnosis in 7/18 cases, one case was diagnosed as cutaneous candidiasis, and diagnosis of immunobullous lesions could be excluded in 5/18 cases. Out of the 19 suspected cases of herpetic infections, viral cytopathic effect was observed in 8/19 cases. Besides immunobullous lesions and herpetic infections, acantholytic cells were also observed in spongiotic dermatitis and genodermatosis. Dyskeratotic keratinocytes seen in vacuolar interface dermatitis were not easily distinguishable from acantholytic cells on Tzanck smear. Conclusions:Tzanck smear test is an inexpensive and useful diagnostic tool for certain skin diseases. It can aid in establishing a rapid clinical diagnosis and can serve as a useful adjunct to routine histological examination. We recommend the use of Tzanck smear as a first-line investigation for vesiculobullous, erosive, and pustular lesions.
journal_name
J Cytoljournal_title
Journal of cytologyauthors
Panwar H,Joshi D,Goel G,Asati D,Majumdar K,Kapoor Ndoi
10.4103/JOC.JOC_88_16subject
Has Abstractpub_date
2017-10-01 00:00:00pages
179-182issue
4eissn
0970-9371issn
0974-5165pii
JCytol-34-179journal_volume
34pub_type
杂志文章abstract::Primary lymphoma of the parotid gland is relatively rare and constitutes about 4-5% of extranodal lymphomas. The majority of them is non-Hodgkin lymphoma (NHL) and is B cell in nature. We report a case of primary diffuse large B-cell lymphoma (DLBCL) of the parotid gland in an elderly male. The case was diagnosed on f...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.182539
更新日期:2016-04-01 00:00:00
abstract::Extra-abdominal desmoid tumors are known as aggressive fibromatosis (AFM). Synchronous and metachronous multicentric aggressive fibromatosis are rare lesions and pose dilemma in diagnosis and management. A rare and interesting case of recurrent multicentric, synchronous AFM is presented which to the best of our knowle...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.93227
更新日期:2012-01-01 00:00:00
abstract::Castleman's disease (CD), also called giant lymph nodal hyperplasia, is a lymphoproliferative disorder secondary to lymphoid follicle hyperplasia and marked capillary proliferation with endothelial hyperplasia. It presents as enlarged lymph nodes in the mediastinum, neck, groin, axilla and other sites. On clinical exa...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.73306
更新日期:2010-10-01 00:00:00
abstract::Prostatic adenocarcinoma (PA) is a common visceral malignancy of elderly men. Cutaneous metastasis of PA is rare. The incidence is <1%. A 55-year-old man presented with urinary symptoms and multiple cutaneous nodules around suprapubic region, inner aspect of both thighs and scrotum. Fine-needle aspiration cytology (FN...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.160568
更新日期:2015-04-01 00:00:00
abstract::Tissue diagnosis of small round cell tumors relies heavily on immunohistochemical staining. Two of the small round cell tumors, namely neuroblastoma and primitive neuroectodermal tumor, have considerable morphologic overlap. Many studies suggest that CD99 positivity virtually excludes the diagnosis of neuroblastoma. W...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.97162
更新日期:2012-04-01 00:00:00
abstract::Chondroid syringoma is a rare benign adnexal tumor of sweat glands with microscopic resemblance to the salivary gland pleomorphic adenoma. Cytology is rarely utilized for preoperative assessment of these slow-growing, small, nodular lesions. Definitive cytological diagnosis is also quite difficult, and majority of the...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.145659
更新日期:2014-07-01 00:00:00
abstract::Xanthogranulomatous reaction can occur in any organ but the most common sites are kidney and gallbladder. Xanthogranulomatous appendicitis (XA) is a rare clinical entity. There are a few case reports of XA diagnosed on histopathology but none on cytology. Here we report a case of a 47-year-old lady who presented with ...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.197619
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Cancer of the cervix has been considered as one of the preventable cancers. This study is the first published research addressing the screening of cancer of the cervix in the eastern region of Saudi Arabia. AIM:This study aims to detect the prevalence of abnormal epithelial changes and its types in the east...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.86343
更新日期:2011-10-01 00:00:00
abstract::Histoplasmosis is a mycotic infection caused by dimorphic fungus, Histoplasma capsulatum. The organisms are usually found within the cells (macrophages). This organism mostly affects lungs in immunocompetent individuals and disseminated forms are seen in immunocompromised cases. Here, we describe a case of disseminate...
journal_title:Journal of cytology
pub_type:
doi:10.4103/JOC.JOC_74_16
更新日期:2017-07-01 00:00:00
abstract:Background:Conventional Papanicolaou (Pap) stain has undergone many modifications; of these, ultrafast Pap stain is the most popular as it shortens the turnaround time of reporting. Application of modified ultrafast Pap (MUFP) stain in the evaluation of fine needle aspiration (FNA) samples and body fluids are scanty. ...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_94_17
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Image-guided fine-needle aspiration cytology (FNAC) serves as first-line diagnostic modalities for the assessment of mural thickening of the gallbladder (GB). AIM:The main objective of the present study was to correlate the diagnostic accuracy of preoperative image-guided FNAC of the thickened GB wall based...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.171231
更新日期:2015-10-01 00:00:00
abstract::Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) is a rare benign disease of unknown etiology presenting with massive lymphadenopathy. These cases can often be misdiagnosed as lymphoma. Hence, it is important to distinguish Rosai-Dorfman disease from lymphoma and other causes of histiocytosis b...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.55229
更新日期:2009-04-01 00:00:00
abstract::[This corrects the article on p. 153 in vol. 32, PMID: 26729974.]. ...
journal_title:Journal of cytology
pub_type: 已发布勘误
doi:10.4103/0970-9371.175533
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:The cytological examinations of serous effusions have been well-accepted, and a positive diagnosis is often considered as a definitive diagnosis. It helps in staging, prognosis and management of the patients in malignancies and also gives information about various inflammatory and non-inflammatory lesions. D...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.93210
更新日期:2012-01-01 00:00:00
abstract:Background:Skin adnexal neoplasms are relatively rare and thus uncommonly encountered in routine pathology practice. Aims:The present study was conducted with the aim to diagnose various skin adnexal tumors on fine-needle aspiration cytology (FNAC) followed by confirmation on histopathology and immunohistochemistry of...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_63_17
更新日期:2018-10-01 00:00:00
abstract::Preoperative pathologic diagnosis of pelvic tumors is mandatory for proper management of patients like neoadjuvant chemotherapy and interval debulking. Currently there are many minimally invasive methods available which include fine-needle aspiration cytology (FNAC) and trucut biopsy, mostly complimentary to each othe...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_63_18
更新日期:2018-07-01 00:00:00
abstract::Gaucher's disease is the most common lysosomal storage disorder gene defect, which leads to deficiency or decreased activity of glucocerebrosidase, followed by accumulation of glucosylceramide. There is autosomal recessive transmission leading to varied clinical manifestations. This disease has three main types: Type ...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.59399
更新日期:2009-07-01 00:00:00
abstract:AIM:Surgical pathology service is generally unavailable in most developing countries and comes with challenges. Cytopathology is a reliable, inexpensive adjunct to surgical histopathology. We present a retrospective review of the various cytopathology cases received at the department. MATERIALS AND METHODS:A retrospec...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.197593
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:The role of DNA ploidy in genomic instability of cancer cells and prognosis has been described in a number of studies. The role of the centrosome in cell cycle has also been reported. AIM:In this study, we aimed to investigate the correlation between the centrosome and DNA ploidy in breast cancer in a searc...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.97150
更新日期:2012-04-01 00:00:00
abstract::Adult-type granulosa cell tumors (AGCT) account for 1-2% of all ovarian tumors and 95% of granulosa cell tumors. In AGCT, at the time of peritoneal washing, tumor cells are rarely seen to exfoliate and FIGO stage is raised from IA/IB or IIA/IIB to stage IC or IIC despite the absence of a gross intraepithelial tumor. P...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.107528
更新日期:2013-01-01 00:00:00
abstract::Primary (spontaneous) umbilical endometriosis is very rare with an estimated incidence of 0.5-1% of all patients with endometrial ectopia. Endometriosis is a common gynecological condition, the pelvis being the most common site of the disease. Extrapelvic site is less common and even more difficult to diagnose due to ...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.86355
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Liquid-based cytology (LBC) preparation is a way to improve and refine the fine-needle aspiration (FNA) samples. There are a few studies comparing LBC with conventional smear (CS). AIM:The present study was undertaken to evaluate the utility of manual LBC (MLBC) and CS preparations in various FNA samples. ...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.190446
更新日期:2016-10-01 00:00:00
abstract::Papillary thyroid carcinoma (PTC) is the most common malignant neoplasm of the thyroid. On fine-needle aspiration (FNA) cytology smears of conventional PTC, the background usually shows scanty, bubble gum-like colloid. But the macrofollicular variant and papillary microcarcinoma reveals abundant thin colloid in the ba...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.171252
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:The use of oral exfoliative cytology as a diagnostic aid accentuates the need for establishing an accurate baseline, thereby enabling the comparison of abnormal oral tissue with established baseline. AIMS AND OBJECTIVE:To detect any changes in the nuclear area (NA), cytoplasmic area (CA), and nuclear:cytopl...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.80745
更新日期:2011-04-01 00:00:00
abstract:Background:Human papilloma virus (HPV) infection is the major etiologic agent of cervical carcinoma. The aim of this study was to determine the prevalence of HPV infection and genotype distribution in cervical swabs from 2,234 Turkish and 357 Albanian women with similar lifestyles from two different countries. Materia...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_162_17
更新日期:2018-10-01 00:00:00
abstract:Context:Fine needle aspiration (FNA) plays a crucial role in the evaluation of patients with thyroid lesions. The Bethesda system for reporting thyroid cytopathology (TBSRTC) was designed with a mission to standardize the process of diagnosis and management of thyroid lesions by FNA cytology (FNAC). Aim:We aim to see ...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/JOC.JOC_64_18
更新日期:2019-01-01 00:00:00
abstract::A case of lymphoepithelial carcinoma (LEC) occurring in right submandibular gland of a 13-year-old Indian male is presented, wherein the lesion unveiled itself only after multiple fine needle aspiration (FNA) procedures. This unusual neoplasm has high frequency of occurrence in Eskimos and a predilection for the parot...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.101185
更新日期:2012-07-01 00:00:00
abstract:AIM:To evaluate and compare the cytograding of breast cancers using Robinson's and Mouriquand's grading methods. MATERIALS AND METHODS:A 5-year retrospective (from Oct 2000 to Sept 2005) and 1-year prospective study (from Oct 2005 to Oct 2006). A total of 110 fine-needle aspiration cytology (FNAC) cases of breast canc...
journal_title:Journal of cytology
pub_type: 杂志文章
doi:10.4103/0970-9371.70738
更新日期:2010-04-01 00:00:00
abstract::Primary malignant lymphomas of the salivary glands are rare, accounting for 2-5% of salivary gland tumors and 5% of extranodal lymphomas, frequently seen in the parotid gland. There are single case reports mentioned in the literature. Clinical presentation is not characteristic and the disease is often overlooked with...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.190441
更新日期:2016-10-01 00:00:00
abstract::There is only one report on cytological findings of oncocytic variant of chromophobe renal cell carcinoma (RCC). In this article, we report a new case with focus on cytological, and ultrastructural findings. A 60-year-old Japanese man was found to have a right renal tumor on medical checkup. In imprint cytological mat...
journal_title:Journal of cytology
pub_type:
doi:10.4103/0970-9371.168846
更新日期:2015-07-01 00:00:00