Abstract：
:Collagenous spherulosis is a rare entity usually seen in association with benign breast lesions. It is often picked up incidentally with a reported incidence of about 0.2% in cytological material. There are very few reports describing cytomorphological features of collagenous spherulosis. To the best of our knowledge this is the only case reported from the middle-east region. The presence of hyaline spherules surrounded by a single layer of benign myoepithelial cells is the hallmark of collagenous spherulosis on FNA. However, due to close cytological resemblance, it can be misdiagnosed as adenoid cystic carcinoma of the breast. A 40-year-old woman presented with a history of a painless lump in the infraareolar region of left breast for a year. Fine needle aspiration was performed. The smears showed scanty cellularity comprising of cohesive clusters and a few branching fragments of benign ductal epithelial cells closely intermingled with many spherical, acellular homogenous hyaline globules. Few bare bipolar nuclei were noted in the background. A diagnosis of collagenous spherulosis associated with benign proliferative breast disease was made. Cytopathologists need to be aware of this entity in order to differentiate it from adenoid cystic carcinoma of the breast which requires radical treatment.
journal_name
J Cytoljournal_title
Journal of cytologyauthors
Gokhale UA,Nanda A,Pillai GRdoi
10.4103/0970-9371.138683subject
Has Abstractpub_date
2014-04-01 00:00:00pages
99-101issue
2eissn
0970-9371issn
0974-5165pii
JCytol-31-99journal_volume
31pub_type
abstract：:Salivary gland small cell carcinoma (SGSmCC) is extremely rare, accounting for less than 1% of salivary gland tumors. A 42-year-old female patient came to the outpatient clinic due to a mass localized in the left submandibular space and that had been growing since 3-4 months. The fine needle aspiration cytology (FNAC)...
journal_title：Journal of cytology
pub_type：
doi：10.4103/0970-9371.175509
更新日期：2016-01-01 00:00:00
abstract：:Primary (spontaneous) umbilical endometriosis is very rare with an estimated incidence of 0.5-1% of all patients with endometrial ectopia. Endometriosis is a common gynecological condition, the pelvis being the most common site of the disease. Extrapelvic site is less common and even more difficult to diagnose due to ...
journal_title：Journal of cytology
pub_type：
doi：10.4103/0970-9371.86355
更新日期：2011-10-01 00:00:00
abstract：BACKGROUND:Fine needle aspiration cytology (FNAC) of oral and maxillofacial region has not been widely utilized for diagnosis due to diversity of lesion types, heterogeneity of cell populations and difficulties in reaching and aspirating these lesions. AIM:Our aim was to demonstrate the effectiveness of this cheap and...
journal_title：Journal of cytology
pub_type： 杂志文章
doi：10.4103/0970-9371.83461
更新日期：2011-07-01 00:00:00
abstract：Background:Cervical cancer is one of the most frequent malignancies in women. Micronucleus (MN) testing has gained popularity as a biomarker in early diagnosis of many types of cancer. Aims:This study aims to investigate the role of MN testing on early detection of cervical cancer and the effect of boron exposure on c...
journal_title：Journal of cytology
pub_type： 杂志文章
doi：10.4103/JOC.JOC_185_17
更新日期：2019-04-01 00:00:00
abstract：Introduction:The mortality due to uterine cervical cancer has been gradually increasing in women under 40 years of age (U40) in Japan. We investigated the effect of high-risk human papillomavirus (HR-HPV) on U40 subjects without any overt cytological abnormalities. Materials and Methods:We retrospectively examined the...
journal_title：Journal of cytology
pub_type： 杂志文章
doi：10.4103/JOC.JOC_148_17
更新日期：2019-07-01 00:00:00
abstract：:Castleman's disease (CD), also called giant lymph nodal hyperplasia, is a lymphoproliferative disorder secondary to lymphoid follicle hyperplasia and marked capillary proliferation with endothelial hyperplasia. It presents as enlarged lymph nodes in the mediastinum, neck, groin, axilla and other sites. On clinical exa...
journal_title：Journal of cytology
pub_type：
doi：10.4103/0970-9371.73306
更新日期：2010-10-01 00:00:00
abstract：:Primary splenic angiosarcoma is a rare malignant vascular neoplasm of mesenchymal origin. The tumor is highly aggressive and has a high metastatic potential. It is usually diagnosed on histopathological examination of splenectomy specimen. Only few cases of angiosarcoma diagnosed by fine-needle aspiration (FNA) cytolo...
journal_title：Journal of cytology
pub_type：
doi：10.4103/JOC.JOC_148_16
更新日期：2018-04-01 00:00:00
abstract：:Rosai-Dorfman disease, that is, sinus histiocytosis with massive lymphadenopathy is a benign systemic proliferative disorder of histiocytes. The typical clinical presentation of the disease includes bilateral painless massive lymphadenopathy, fever and polyclonal hypergammaglobulinemia. Extranodal involvement is prese...
journal_title：Journal of cytology
pub_type：
doi：10.4103/0970-9371.83473
更新日期：2011-07-01 00:00:00
abstract：BACKGROUND:Image-guided fine-needle aspiration cytology (FNAC) serves as first-line diagnostic modalities for the assessment of mural thickening of the gallbladder (GB). AIM:The main objective of the present study was to correlate the diagnostic accuracy of preoperative image-guided FNAC of the thickened GB wall based...
journal_title：Journal of cytology
pub_type： 杂志文章
doi：10.4103/0970-9371.171231
更新日期：2015-10-01 00:00:00
abstract：:Malignant mesothelioma of pleura is a locally aggressive rare neoplasm of mesothelial cells, which produces distant metastasis in advanced stages of its course. It is exceptional for patients to present with metastasis prior to the detection of primary tumor in the pleura. Here, we report a case of malignant mesotheli...
journal_title：Journal of cytology
pub_type：
doi：10.4103/0970-9371.216123
更新日期：2017-10-01 00:00:00
abstract：:Chondroid syringoma is a rare benign adnexal tumor of sweat glands with microscopic resemblance to the salivary gland pleomorphic adenoma. Cytology is rarely utilized for preoperative assessment of these slow-growing, small, nodular lesions. Definitive cytological diagnosis is also quite difficult, and majority of the...
journal_title：Journal of cytology
pub_type：
doi：10.4103/0970-9371.145659
更新日期：2014-07-01 00:00:00
abstract：BACKGROUND:The role of DNA ploidy in genomic instability of cancer cells and prognosis has been described in a number of studies. The role of the centrosome in cell cycle has also been reported. AIM:In this study, we aimed to investigate the correlation between the centrosome and DNA ploidy in breast cancer in a searc...
journal_title：Journal of cytology
pub_type： 杂志文章
doi：10.4103/0970-9371.97150
更新日期：2012-04-01 00:00:00
abstract：BACKGROUND:It is now known that the disease process of diabetes has effects on various tissues of the body. The following study was done to analyze the effects of diabetes on oral tissues. AIMS:To study the morphology and cytomorphometry of the cells obtained in cytologic smears from the buccal mucosa of diabetic pati...
journal_title：Journal of cytology
pub_type： 杂志文章
doi：10.4103/0970-9371.73291
更新日期：2010-10-01 00:00:00
abstract：:Tuberculosis of cervix is a rare disease. Tuberculosis usually affects women of childbearing age, indicating hormone dependence of infection. The patient presents with menstrual irregularities, infertility or vaginal discharge. Cervical lesions presents as papillary/vegetative growth or ulceration mimicking cervical c...
journal_title：Journal of cytology
pub_type：
doi：10.4103/0970-9371.93242
更新日期：2012-01-01 00:00:00
abstract：:Primary malignant lymphomas of the salivary glands are rare, accounting for 2-5% of salivary gland tumors and 5% of extranodal lymphomas, frequently seen in the parotid gland. There are single case reports mentioned in the literature. Clinical presentation is not characteristic and the disease is often overlooked with...
journal_title：Journal of cytology
pub_type：
doi：10.4103/0970-9371.190441
更新日期：2016-10-01 00:00:00
abstract：INTRODUCTION:Human immunodeficiency virus (HIV) infection has become a global pandemic. Persistent generalized lymphadenopathy (PGL) is very common manifestation of HIV infection. Moreover, different opportunistic infections such as tuberculosis (TB) and malignancies may present with lymphadenopathy. Mycobacterium aviu...
journal_title：Journal of cytology
pub_type： 杂志文章
doi：10.4103/0970-9371.182518
更新日期：2016-04-01 00:00:00
abstract：:Tissue diagnosis of small round cell tumors relies heavily on immunohistochemical staining. Two of the small round cell tumors, namely neuroblastoma and primitive neuroectodermal tumor, have considerable morphologic overlap. Many studies suggest that CD99 positivity virtually excludes the diagnosis of neuroblastoma. W...
journal_title：Journal of cytology
pub_type：
doi：10.4103/0970-9371.97162
更新日期：2012-04-01 00:00:00
abstract：Context:Intraoperative pathological assessment provides valuable information in a patient's diagnosis and management. Touch imprint/crush cytology is simple, rapid, and cost-effective. Also, imprint smears give excellent cytomorphology. Aims:To assess the utility and feasibility of intraoperative cytology technique as...
journal_title：Journal of cytology
pub_type： 杂志文章
doi：10.4103/JOC.JOC_94_19
更新日期：2020-07-01 00:00:00
abstract：:Xanthogranulomatous reaction can occur in any organ but the most common sites are kidney and gallbladder. Xanthogranulomatous appendicitis (XA) is a rare clinical entity. There are a few case reports of XA diagnosed on histopathology but none on cytology. Here we report a case of a 47-year-old lady who presented with ...
journal_title：Journal of cytology
pub_type：
doi：10.4103/0970-9371.197619
更新日期：2017-01-01 00:00:00
abstract：:Synovial sarcomas are rare tumors accounting for approximately 5-10% of soft tissue sarcomas. They occur predominantly in the extremities, followed by head and neck. Primary pulmonary sarcomas are very rare and comprise only 0.5% of all primary lung malignancies. The diagnosis is established only after sarcomas like p...
journal_title：Journal of cytology
pub_type：
doi：10.4103/0970-9371.155240
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:Oral lichen planus (OLP) is one of the potentially malignant disorders (PMDs) with a malignancy rate of 0.2-2%. Aneuploidy is considered to be one of the important markers for malignant transformation and DNA-image cytometry (DIC) has been successfully employed in oral mucosal PMDs and also in tumors of the ...
journal_title：Journal of cytology
pub_type： 杂志文章
doi：10.4103/0970-9371.145629
更新日期：2014-07-01 00:00:00
abstract：BACKGROUND:It has been shown that cigarette smoking as well as diabetes mellitus can produce cytomorphometric alterations in oral epithelial cells with the significant increase in the nuclear area (NA) and significant decrease in the cytoplasmic/nuclear ratio in comparison to healthy control. However, the synergistic e...
journal_title：Journal of cytology
pub_type： 杂志文章
doi：10.4103/0970-9371.112653
更新日期：2013-04-01 00:00:00
abstract：:Fibromatosis colli is a peculiar, benign fibrous growth of the sternocleidomastoid that usually appears during the first few weeks of life and is often associated with muscular torticollis. Fibromatosis colli (FC) is seen in children born after difficult, prolonged labor, assisted delivery, and breech deliveries. Clin...
journal_title：Journal of cytology
pub_type：
doi：10.4103/0970-9371.54869
更新日期：2009-01-01 00:00:00
abstract：:Lung cancer (LC) is the leading cause of cancer-related mortality. Unfortunately, most patients of LC present at the advanced stage of the disease with a poor prognosis and 1-year survival of less than 20%. At the advanced stage of the disease, surgical resection cannot be possible, hence small biopsy or cytology spec...
journal_title：Journal of cytology
pub_type： 杂志文章
doi：10.4103/JOC.JOC_135_18
更新日期：2019-04-01 00:00:00
abstract：:[This corrects the article on p. 153 in vol. 32, PMID: 26729974.]. ...
journal_title：Journal of cytology
pub_type： 已发布勘误
doi：10.4103/0970-9371.175533
更新日期：2016-01-01 00:00:00
abstract：:Primary lymphoma of the parotid gland is relatively rare and constitutes about 4-5% of extranodal lymphomas. The majority of them is non-Hodgkin lymphoma (NHL) and is B cell in nature. We report a case of primary diffuse large B-cell lymphoma (DLBCL) of the parotid gland in an elderly male. The case was diagnosed on f...
journal_title：Journal of cytology
pub_type：
doi：10.4103/0970-9371.182539
更新日期：2016-04-01 00:00:00
abstract：:Histoplasmosis is a mycotic infection caused by dimorphic fungus, Histoplasma capsulatum. The organisms are usually found within the cells (macrophages). This organism mostly affects lungs in immunocompetent individuals and disseminated forms are seen in immunocompromised cases. Here, we describe a case of disseminate...
journal_title：Journal of cytology
pub_type：
doi：10.4103/JOC.JOC_74_16
更新日期：2017-07-01 00:00:00
abstract：INTRODUCTION:Cervical intraepithelial neoplasia and cervical cancer remain important health problems. Cervical cytology by Papanicolaou (Pap) smears is an effective means of screening for cervical premalignant and malignant conditions. AIM:The aim of this study was to assess the prevalence of cervical dysplasia in pre...
journal_title：Journal of cytology
pub_type： 杂志文章
doi：10.4103/0970-9371.126659
更新日期：2013-10-01 00:00:00
abstract：:A case of lymphoepithelial carcinoma (LEC) occurring in right submandibular gland of a 13-year-old Indian male is presented, wherein the lesion unveiled itself only after multiple fine needle aspiration (FNA) procedures. This unusual neoplasm has high frequency of occurrence in Eskimos and a predilection for the parot...
journal_title：Journal of cytology
pub_type：
doi：10.4103/0970-9371.101185
更新日期：2012-07-01 00:00:00
abstract：Background:Human papilloma virus (HPV) infection is the major etiologic agent of cervical carcinoma. The aim of this study was to determine the prevalence of HPV infection and genotype distribution in cervical swabs from 2,234 Turkish and 357 Albanian women with similar lifestyles from two different countries. Materia...
journal_title：Journal of cytology
pub_type： 杂志文章
doi：10.4103/JOC.JOC_162_17
更新日期：2018-10-01 00:00:00
