Abstract:
:A pan-genome is the union of the gene sets of all the individuals of a clade or a species and it provides a new dimension of genome complexity with the presence/absence variations (PAVs) of genes among these genomes. With the progress of sequencing technologies, pan-genome study is becoming affordable for eukaryotes with large-sized genomes. The Asian cultivated rice, Oryza sativa L., is one of the major food sources for the world and a model organism in plant biology. Recently, the 3000 Rice Genome Project (3K RGP) sequenced more than 3000 rice genomes with a mean sequencing depth of 14.3×, which provided a tremendous resource for rice research. In this paper, we present a genome browser, Rice Pan-genome Browser (RPAN), as a tool to search and visualize the rice pan-genome derived from 3K RGP. RPAN contains a database of the basic information of 3010 rice accessions, including genomic sequences, gene annotations, PAV information and gene expression data of the rice pan-genome. At least 12 000 novel genes absent in the reference genome were included. RPAN also provides multiple search and visualization functions. RPAN can be a rich resource for rice biology and rice breeding. It is available at http://cgm.sjtu.edu.cn/3kricedb/ or http://www.rmbreeding.cn/pan3k.
journal_name
Nucleic Acids Resjournal_title
Nucleic acids researchauthors
Sun C,Hu Z,Zheng T,Lu K,Zhao Y,Wang W,Shi J,Wang C,Lu J,Zhang D,Li Z,Wei Cdoi
10.1093/nar/gkw958subject
Has Abstractpub_date
2017-01-25 00:00:00pages
597-605issue
2eissn
0305-1048issn
1362-4962pii
gkw958journal_volume
45pub_type
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