Nanoscale assembly of superconducting vortices with scanning tunnelling microscope tip.

abstract：:Circadian rhythms of cell division have been observed in several lineages of eukaryotes, especially photosynthetic unicellular eukaryotes. However, the mechanism underlying the circadian regulation of the cell cycle and the nature of the advantage conferred remain unknown. Here, using the unicellular red alga Cyanidio...

journal_title：Nature communications

authors： Miyagishima SY,Fujiwara T,Sumiya N,Hirooka S,Nakano A,Kabeya Y,Nakamura M

更新日期：2014-05-08 00:00:00

abstract：:MAVS and MITA are essential adaptor proteins mediating innate antiviral immune responses against RNA and DNA viruses, respectively. Here we show that RNF115 plays dual roles in response to RNA or DNA virus infections by catalyzing distinct types of ubiquitination of MAVS and MITA at different phases of viral infection...

journal_title：Nature communications

authors： Zhang ZD,Xiong TC,Yao SQ,Wei MC,Chen M,Lin D,Zhong B

更新日期：2020-11-02 00:00:00

abstract：:Maternal glucose levels during pregnancy impact the developing fetus, affecting metabolic health both early and later on in life. Both genetic and environmental factors influence maternal metabolism, but little is known about the genetic mechanisms that alter glucose metabolism during pregnancy. Here, we report that h...

journal_title：Nature communications

authors： Guo C,Ludvik AE,Arlotto ME,Hayes MG,Armstrong LL,Scholtens DM,Brown CD,Newgard CB,Becker TC,Layden BT,Lowe WL,Reddy TE

更新日期：2015-02-04 00:00:00

abstract：:The charge density wave in the high-temperature superconductor YBa2Cu3O7-x (YBCO) has two different ordering tendencies differentiated by their c-axis correlations. These correspond to ferro- (F-CDW) and antiferro- (AF-CDW) couplings between CDWs in neighbouring CuO2 bilayers. This discovery has prompted several funda...

journal_title：Nature communications

authors： Choi J,Ivashko O,Blackburn E,Liang R,Bonn DA,Hardy WN,Holmes AT,Christensen NB,Hücker M,Gerber S,Gutowski O,Rütt U,Zimmermann MV,Forgan EM,Hayden SM,Chang J

更新日期：2020-02-20 00:00:00

abstract：:Pioneer transcription factors can engage nucleosomal DNA, which leads to local chromatin remodeling and to the establishment of transcriptional competence. However, the impact of enhancer priming by pioneer factors on the temporal control of gene expression and on mitotic memory remains unclear. Here we employ quantit...

journal_title：Nature communications

authors： Dufourt J,Trullo A,Hunter J,Fernandez C,Lazaro J,Dejean M,Morales L,Nait-Amer S,Schulz KN,Harrison MM,Favard C,Radulescu O,Lagha M

更新日期：2018-12-05 00:00:00

abstract：:Increased somatic mitochondrial DNA (mtDNA) mutagenesis causes premature aging in mice, and mtDNA damage accumulates in the human brain with aging and neurodegenerative disorders such as Parkinson disease (PD). Here, we study the complete spectrum of mtDNA changes, including deletions, copy-number variation and point ...

journal_title：Nature communications

authors： Dölle C,Flønes I,Nido GS,Miletic H,Osuagwu N,Kristoffersen S,Lilleng PK,Larsen JP,Tysnes OB,Haugarvoll K,Bindoff LA,Tzoulis C

更新日期：2016-11-22 00:00:00

abstract：:Nanoparticle-mediated delivery of functional macromolecules is a promising method for treating a variety of human diseases. Among nanoparticles, cell-derived exosomes have recently been highlighted as a new therapeutic strategy for the in vivo delivery of nucleotides and chemical drugs. Here we describe a new tool for...

journal_title：Nature communications

authors： Yim N,Ryu SW,Choi K,Lee KR,Lee S,Choi H,Kim J,Shaker MR,Sun W,Park JH,Kim D,Heo WD,Choi C

更新日期：2016-07-22 00:00:00

abstract：:Hydrogen, the simplest element in the universe, has a surprisingly complex phase diagram. Because of applications to planetary science, inertial confinement fusion and fundamental physics, its high-pressure properties have been the subject of intense study over the past two decades. While sophisticated static experime...

journal_title：Nature communications

authors： Davis P,Döppner T,Rygg JR,Fortmann C,Divol L,Pak A,Fletcher L,Becker A,Holst B,Sperling P,Redmer R,Desjarlais MP,Celliers P,Collins GW,Landen OL,Falcone RW,Glenzer SH

更新日期：2016-04-15 00:00:00

abstract：:Magnetic skyrmion, a topologically stable spin-swirling object, can host emergent electromagnetism, as exemplified by the topological Hall effect and electric-current-driven skyrmion motion. To achieve efficient manipulation of nano-sized functional spin textures, it is imperative to exploit the resonant motion of sky...

journal_title：Nature communications

authors： Okamura Y,Kagawa F,Mochizuki M,Kubota M,Seki S,Ishiwata S,Kawasaki M,Onose Y,Tokura Y

更新日期：2013-01-01 00:00:00

abstract：:Macrophages serve multiple functions including immune regulation, morphogenesis, tissue homeostasis and healing reactions. The current paradigm holds that mammary gland macrophages first arise postnatally during the prepubertal period from the bone marrow-derived monocytes. Here we delineate the origins of tissue-resi...

journal_title：Nature communications

authors： Jäppinen N,Félix I,Lokka E,Tyystjärvi S,Pynttäri A,Lahtela T,Gerke H,Elima K,Rantakari P,Salmi M

更新日期：2019-01-17 00:00:00

abstract：:Recent advances in nonlinear optics have revolutionized integrated photonics, providing on-chip solutions to a wide range of new applications. Currently, state of the art integrated nonlinear photonic devices are mainly based on dielectric material platforms, such as Si3N4 and SiO2. While semiconductor materials featu...

journal_title：Nature communications

authors： Chang L,Xie W,Shu H,Yang QF,Shen B,Boes A,Peters JD,Jin W,Xiang C,Liu S,Moille G,Yu SP,Wang X,Srinivasan K,Papp SB,Vahala K,Bowers JE

更新日期：2020-03-12 00:00:00

abstract：:Mutators represent a successful strategy in rapidly adapting asexual populations, but theory predicts their eventual extinction due to their unsustainably large deleterious load. While antimutator invasions have been documented experimentally, important discrepancies among studies remain currently unexplained. Here we...

journal_title：Nature communications

authors： Couce A,Tenaillon O

更新日期：2019-07-15 00:00:00

abstract：:Broomcorn millet (Panicum miliaceum L.) has strong tolerance to abiotic stresses, and is probably one of the oldest crops, with its earliest cultivation that dated back to ca. ~10,000 years. We report here its genome assembly through a combination of PacBio sequencing, BioNano, and Hi-C (in vivo) mapping. The 18 super...

journal_title：Nature communications

authors： Shi J,Ma X,Zhang J,Zhou Y,Liu M,Huang L,Sun S,Zhang X,Gao X,Zhan W,Li P,Wang L,Lu P,Zhao H,Song W,Lai J

更新日期：2019-01-25 00:00:00

abstract：:Predictable stereoselective formation of supramolecular assembly is generally believed to be an important but complicated process. Here, we show that point chirality of a ligand decisively influences its supramolecular assembly behavior. We designed three closely related chiral ligands with different point chiralities...

journal_title：Nature communications

authors： Yeung CT,Yim KH,Wong HY,Pal R,Lo WS,Yan SC,Yee-Man Wong M,Yufit D,Smiles DE,McCormick LJ,Teat SJ,Shuh DK,Wong WT,Law GL

更新日期：2017-10-24 00:00:00

abstract：:We have been alerted that in our recent Article the calculations used to transform the heritability from the observed scale to the liability scale did not take into account the individuals in category 2 of the baldness scale, who were removed in our original analysis. This led to an overestimation of the heritability ...

journal_title：Nature communications

authors： Pirastu N,Joshi PK,de Vries PS,Cornelis MC,McKeigue PM,Keum N,Franceschini N,Colombo M,Giovannucci EL,Spiliopoulou A,Franke L,North KE,Kraft P,Morrison AC,Esko T,Wilson JF

更新日期：2018-06-29 00:00:00

abstract：:The photon-like behavior of electrons in graphene causes unusual confinement properties that depend strongly on the geometry and strength of the surrounding potential. We report bottom-up synthesis of atomically-precise one-dimensional (1D) arrays of point charges on graphene that allow exploration of a new type of su...

journal_title：Nature communications

authors： Lu J,Tsai HZ,Tatan AN,Wickenburg S,Omrani AA,Wong D,Riss A,Piatti E,Watanabe K,Taniguchi T,Zettl A,Pereira VM,Crommie MF

更新日期：2019-01-29 00:00:00

abstract：:How stem cells give rise to epidermis is unclear despite the crucial role the epidermis plays in barrier and appendage formation. Here we use single cell-RNA sequencing to interrogate basal stem cell heterogeneity of human interfollicular epidermis and find four spatially distinct stem cell populations at the top and ...

journal_title：Nature communications

authors： Wang S,Drummond ML,Guerrero-Juarez CF,Tarapore E,MacLean AL,Stabell AR,Wu SC,Gutierrez G,That BT,Benavente CA,Nie Q,Atwood SX

更新日期：2020-08-25 00:00:00

abstract：:Calcium ions (Ca(2+)) function as universal second messengers in eukaryotic cells, including immune cells. Ca(2+) is crucial for peripheral T-lymphocyte activation and effector functions, and influences thymocyte selection and motility in the developing thymus. However, the role of Ca(2+) signalling in early T-lymphoc...

journal_title：Nature communications

authors： Ouyang K,Leandro Gomez-Amaro R,Stachura DL,Tang H,Peng X,Fang X,Traver D,Evans SM,Chen J

更新日期：2014-09-12 00:00:00

abstract：:Solar radio observations provide a unique diagnostic of the outer solar atmosphere. However, the inhomogeneous turbulent corona strongly affects the propagation of the emitted radio waves, so decoupling the intrinsic properties of the emitting source from the effects of radio wave propagation has long been a major cha...

journal_title：Nature communications

authors： Kontar EP,Yu S,Kuznetsov AA,Emslie AG,Alcock B,Jeffrey NLS,Melnik VN,Bian NH,Subramanian P

更新日期：2017-11-15 00:00:00

abstract：:The fate of the enormous amount of reactive nitrogen released to the environment by human activities in India is unknown. Here we show occurrence of seasonal stratification and generally low concentrations of dissolved inorganic combined nitrogen, and high molecular nitrogen (N2) to argon ratio, thus suggesting season...

journal_title：Nature communications

authors： Naqvi SWA,Lam P,Narvenkar G,Sarkar A,Naik H,Pratihary A,Shenoy DM,Gauns M,Kurian S,Damare S,Duret M,Lavik G,Kuypers MMM

更新日期：2018-03-28 00:00:00

abstract：:The Hippo pathway is an evolutionarily conserved regulator of organ size and tumorigenesis that negatively regulates cell growth and survival. Here we report that Yes-associated protein (YAP), the terminal effector of the Hippo pathway, interacts with FoxO1 in the nucleus of cardiomyocytes, thereby promoting survival....

journal_title：Nature communications

authors： Shao D,Zhai P,Del Re DP,Sciarretta S,Yabuta N,Nojima H,Lim DS,Pan D,Sadoshima J

更新日期：2014-01-01 00:00:00

abstract：:Circular RNAs (circRNAs) have recently gained substantial attention in the cancer research field where most, including the putative oncogene ciRS-7 (CDR1as), have been proposed to function as competitive endogenous RNAs (ceRNAs) by sponging specific microRNAs. Here, we report the first spatially resolved cellular expr...

journal_title：Nature communications

authors： Kristensen LS,Ebbesen KK,Sokol M,Jakobsen T,Korsgaard U,Eriksen AC,Hansen TB,Kjems J,Hager H

更新日期：2020-09-11 00:00:00

abstract：:Irrigated agriculture has important implications for achieving the United Nations Sustainable Development Goals. However, there is a lack of systematic and quantitative analyses of its impacts on food-energy-water-CO2 nexus. Here we studied impacts of irrigated agriculture on food-energy-water-CO2 nexus across food se...

journal_title：Nature communications

authors： Xu Z,Chen X,Liu J,Zhang Y,Chau S,Bhattarai N,Wang Y,Li Y,Connor T,Li Y

更新日期：2020-11-17 00:00:00

abstract：:Replication errors are the main cause of mitochondrial DNA (mtDNA) mutations and a compelling approach to decrease mutation levels would therefore be to increase the fidelity of the catalytic subunit (POLγA) of the mtDNA polymerase. Here we genomically engineer the tamas locus, encoding fly POLγA, and introduce allele...

journal_title：Nature communications

authors： Bratic A,Kauppila TE,Macao B,Grönke S,Siibak T,Stewart JB,Baggio F,Dols J,Partridge L,Falkenberg M,Wredenberg A,Larsson NG

更新日期：2015-11-10 00:00:00

abstract：:Detection of Identical-By-Descent (IBD) segments provides a fundamental measure of genetic relatedness and plays a key role in a wide range of analyses. We develop FastSMC, an IBD detection algorithm that combines a fast heuristic search with accurate coalescent-based likelihood calculations. FastSMC enables biobank-s...

journal_title：Nature communications

authors： Nait Saada J,Kalantzis G,Shyr D,Cooper F,Robinson M,Gusev A,Palamara PF

更新日期：2020-11-30 00:00:00

abstract：:Polymorphism is a remarkable concept in chemistry, materials science, computer science, and biology. Whether it is the ability of a material to exist in two or more crystal structures, a single interface connecting to two different entities, or alternative phenotypes of an organism, polymorphism determines function an...

journal_title：Nature communications

authors： Li L,Salamończyk M,Shadpour S,Zhu C,Jákli A,Hegmann T

更新日期：2018-02-19 00:00:00

abstract：:Although the changes in melting behaviour on the nanoscale have long attracted the interest of researchers, the mechanism by which nanoparticles melt remains an open problem. We report the direct observation, at atomic resolution, of surface melting in individual size-selected Au clusters (2-5 nm diameter) supported o...

journal_title：Nature communications

authors： Foster DM,Pavloudis T,Kioseoglou J,Palmer RE

更新日期：2019-06-13 00:00:00

abstract：:Chiral magnets are an emerging class of topological matter harboring localized and topologically protected vortex-like magnetic textures called skyrmions, which are currently under intense scrutiny as an entity for information storage and processing. Here, on the level of micromagnetics we rigorously show that chiral ...

journal_title：Nature communications

authors： Hoffmann M,Zimmermann B,Müller GP,Schürhoff D,Kiselev NS,Melcher C,Blügel S

更新日期：2017-08-21 00:00:00

abstract：:Dynamic disruption and reassembly of promoter-proximal nucleosomes is a conserved hallmark of transcriptionally active chromatin. Histone H3-K56 acetylation (H3K56Ac) enhances these turnover events and promotes nucleosome assembly during S phase. Here we sequence nascent transcripts to investigate the impact of H3K56A...

journal_title：Nature communications

authors： Topal S,Vasseur P,Radman-Livaja M,Peterson CL

更新日期：2019-09-26 00:00:00

abstract：:Cellular events that occur across the seminiferous epithelium in the mammalian testis during spermatogenesis are tightly coordinated by biologically active peptides released from laminin chains. Laminin-γ3 domain IV is released at the apical ectoplasmic specialization during spermiation and mediates restructuring of t...

journal_title：Nature communications

authors： Su L,Mruk DD,Lie PP,Silvestrini B,Cheng CY

更新日期：2012-01-01 00:00:00