Detection of Staphylococcus aureus in cystic fibrosis patients using breath VOC profiles.

abstract：:Despite growing interest and considerable progress in breath research over the last decade, standardized practices for the sampling and analysis of breath gas volatiles remain elusive. The primary reasons for this are (a) the rich chemical diversity of exhaled breath that covers an extensive range of volatile organic ...

journal_title：Journal of breath research

authors： Herbig J,Beauchamp J

更新日期：2014-09-01 00:00:00

abstract：:Reactive oxygen species are associated with tissue inflammation and injury. Our laboratory has demonstrated that ethane, a stable product of lipid peroxidation, in exhaled breath can be used to measure total body oxidative stress. Herein patients were studied who underwent outpatient surgery, laproscopic bilateral tub...

journal_title：Journal of breath research

authors： Brown RH,Risby TH

更新日期：2009-03-01 00:00:00

abstract：:Nitrative stress is thought to be involved in the inflammatory process in COPD airways, and the alveolar nitric oxide concentration (CAlv) has been reported to be increased. However, the CAlv levels are also regulated by gas diffusion at alveolar sites. The aim of the study was to assess the relationship between the C...

journal_title：Journal of breath research

authors： Hirano T,Matsunaga K,Sugiura H,Minakata Y,Koarai A,Akamatsu K,Ichikawa T,Furukawa K,Ichinose M

更新日期：2013-12-01 00:00:00

abstract：:Experimental studies using trained dogs to identify breath odour markers of human cancer, published in the recent decade, have been analyzed and compared with the authors' own results. Particular published studies differ as regards the experimental setup, kind of odour samples (breath, urine, tumor tissue, serum), sam...

journal_title：Journal of breath research

authors： Jezierski T,Walczak M,Ligor T,Rudnicka J,Buszewski B

更新日期：2015-05-06 00:00:00

abstract：:Despite recent progress in Critical Care Medicine, sepsis is still a major medical problem with a high rate of mortality and morbidity especially in intensive care units. Oxidative stress induced by inflammation associated with sepsis causes degradation of heme protein, increases microsomal free heme content, promotes...

journal_title：Journal of breath research

authors： Morimatsu H,Takahashi T,Matsusaki T,Hayashi M,Matsumi J,Shimizu H,Matsumi M,Morita K

更新日期：2010-12-01 00:00:00

abstract：:The analysis of volatile organic compounds (VOCs) by an electronic nose (e-nose) is a groundbreaking method that provides distinct exhaled molecular patterns in several respiratory and systemic diseases. It has been shown that an e-nose can detect obstructive sleep apnea (OSA) as well as chronic obstructive pulmonary ...

journal_title：Journal of breath research

authors： Dragonieri S,Quaranta VN,Carratu P,Ranieri T,Resta O

更新日期：2016-11-03 00:00:00

abstract：:In this article, a database of blood:air and fat:air partition coefficients (λ b:a and λ f:a) is reported for estimating 1678 volatile organic compounds recently reported to appear in the volatilome of the healthy human. For this purpose, a quantitative structure-property relationship (QSPR) approach was applied and a...

journal_title：Journal of breath research

authors： Kramer C,Mochalski P,Unterkofler K,Agapiou A,Ruzsanyi V,Liedl KR

更新日期：2016-01-27 00:00:00

abstract：:Breath tests have been used to investigate many physiological functions. Recently, we have developed a breath test system by using a non-invasive technique in conscious rats. In this study, we investigated the effect of atropine sulfate on the gastric emptying and gastrocecal transit time using [1-(13)C]acetic acid an...

journal_title：Journal of breath research

authors： Uchida M,Yoshida K,Shimizu K

更新日期：2009-12-01 00:00:00

abstract：:The objective of this study is to evaluate tonsil odor as a contributor to halitosis and to study the reduction of oral malodor by mouth rinsing, without tonsil treatment. In 48 halitosis patients, tonsil odor and oral malodor were assessed through the 0-5 scale. In tonsil odor assessment, a dental burnisher was inser...

journal_title：Journal of breath research

authors： Talebian A,Tazhibi M,Iranpoor R,Semyari H,Taherzadeh M

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:The analysis of volatile organic compounds (VOCs) in breath allows non-invasive investigations of diseases. Animal studies are conducted as a model to perform research of VOCs and their relation to diseases. In large animal models ruminants were often used as experimental targets. The effect of their physiol...

journal_title：Journal of breath research

authors： Oertel P,Küntzel A,Reinhold P,Köhler H,Schubert JK,Kolb J,Miekisch W

更新日期：2018-05-14 00:00:00

abstract：:Methods for breath sampling and analysis require robust quality assessment to minimise the risk of false discoveries. Planning large-scale multi-site breath metabolite profiling studies also requires careful consideration of systematic and random variation as a result of sampling and analysis techniques. In this study...

journal_title：Journal of breath research

authors： Ahmed WM,Brinkman P,Weda H,Knobel HH,Xu Y,Nijsen TM,Goodacre R,Rattray N,Vink TJ,Santonico M,Pennazza G,Montuschi P,Sterk PJ,Fowler SJ

更新日期：2018-10-30 00:00:00

abstract：:The haloamines, including the chloramines (H(2)NCl, HNCl(2)) and bromamine (H(2)NBr), are diffusible gases that are likely to be produced during inflammation and so may be present as markers of lung inflammation on breath. Although haloamines are quite reactive, it is possible to measure these compounds in humid sampl...

journal_title：Journal of breath research

authors： Storer MK,Dummer JD,Cook J,McEwan M,Epton MJ

更新日期：2011-09-01 00:00:00

abstract：:The discovery of nitric oxide (NO) as a signalling and regulatory molecule and its subsequent detection in the exhaled breath has not only yielded new mechanistic insights but also diagnostic opportunities and therapeutic targets in several important medical conditions. In diseases involving chronic pulmonary inflamma...

journal_title：Journal of breath research

authors： Boshier PR,Hanna GB,Marczin N

更新日期：2013-03-01 00:00:00

abstract：:There is much clinical interest in the development of a low-cost and reliable test for diagnosing inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), two very distinct diseases that can present with similar symptoms. The assessment of stool samples for the diagnosis of gastro-intestinal diseases is in...

journal_title：Journal of breath research

authors： Shepherd SF,McGuire ND,de Lacy Costello BP,Ewen RJ,Jayasena DH,Vaughan K,Ahmed I,Probert CS,Ratcliffe NM

更新日期：2014-06-01 00:00:00

abstract：:Profiling the body chemistry by means of volatile organic compounds (VOCs) in the breath opens exciting new avenues in medical diagnostics. Gas sensors could provide ideal platforms for realizing portable, hand-held breath testing devices in the near future. This review summarizes the latest developments and applicati...

journal_title：Journal of breath research

authors： Tisch U,Haick H

更新日期：2014-06-01 00:00:00

abstract：:There are many respiratory infections such as influenza that cause epidemics. These respiratory infection epidemics can be effectively prevented by determining the presence or absence of infections in patients using frequent tests. We think that self-diagnosis may be possible using a system that can collect and detect...

journal_title：Journal of breath research

authors： Takenaka K,Togashi S,Miyake R,Sakaguchi T,Hide M

更新日期：2016-07-22 00:00:00

abstract：:Fractional exhaled nitric oxide (FENO) is a marker of airway inflammation. Measuring FENO at multiple flow rates enables calculation of NO parameters: bronchial NO output (J awNO), bronchial wall (C awNO) and alveolar (C ANO) NO concentrations, and bronchial diffusion factor of NO (D awNO). FENO is known to rapidly re...

journal_title：Journal of breath research

authors： Karvonen T,Sepponen-Lavikko A,Holm K,Schultz R,Moilanen E,Lehtimäki L

更新日期：2020-11-05 00:00:00

abstract：:Robust methods for breath sampling and analysis are required for potential clinical applications. We have evaluated an improved sampling and experimental design, assessing instrumental and biological variability within and across breath measurements. Calibration curves for selected relevant volatile organic compounds...

journal_title：Journal of breath research

authors： Basanta M,Ibrahim B,Douce D,Morris M,Woodcock A,Fowler SJ

更新日期：2012-06-01 00:00:00

abstract：:In the present longitudinal study, we followed volatile organic compounds (VOCs) excreted in exhaled breath of 20 healthy individuals over time, while adhering to a gluten-free diet for 4 weeks prior to adherence to a normal diet. We used gas chromatography coupled with mass spectrometry (TD-GC-tof-MS) in combination ...

journal_title：Journal of breath research

authors： Baranska A,Tigchelaar E,Smolinska A,Dallinga JW,Moonen EJ,Dekens JA,Wijmenga C,Zhernakova A,van Schooten FJ

更新日期：2013-09-01 00:00:00

abstract：:Bronchiectasis, bronchiolectasis, and bronchiolisation of alveolar regions are salient features of idiopathic pulmonary fibrosis (IPF). We asked whether IPF was associated with physiological changes consistent with increases in the volume of conducting airways, and whether airway volume was related to the severity of ...

journal_title：Journal of breath research

authors： Plantier L,Debray MP,Estellat C,Flamant M,Roy C,Bancal C,Borie R,Israël-Biet D,Mal H,Crestani B,Delclaux C

更新日期：2016-02-01 00:00:00

abstract：:The current diagnostic challenge with diagnosing hepatic encephalopathy (HE) is identifying those with minimal HE as opposed to the more clinically apparent covert/overt HE. Rifaximin, is an effective therapy but earlier identification and treatment of HE could prevent liver disease progression and hospitalization. Ou...

journal_title：Journal of breath research

authors： Arasaradnam RP,McFarlane M,Ling K,Wurie S,O'Connell N,Nwokolo CU,Bardhan KD,Skinner J,Savage RS,Covington JA

更新日期：2016-02-11 00:00:00

abstract：:The measurement of the peak exhaled breath temperature (EBT) during multiple tidal breaths offers an easy, non-invasive tool for monitoring airway inflammation. Chronic obstructive pulmonary disease (COPD) is linked to airway inflammation, which is further aggravated by exacerbations of the disease. However, the peak ...

journal_title：Journal of breath research

authors： Lázár Z,Bikov A,Martinovszky F,Gálffy G,Losonczy G,Horváth I

更新日期：2014-09-18 00:00:00

abstract：:Oxidative stress is associated with numerous health conditions and disorders, and aldehydes are known biomarkers of oxidative stress that can be non-invasively measured in exhaled human breath. Few studies report breath aldehyde levels in human populations, and none claim participant numbers in the hundreds or more. F...

journal_title：Journal of breath research

authors： McCartney MM,Thompson CJ,Klein LR,Ngo JH,Seibel JD,Fabia F,Simms LA,Borras E,Young BS,Lara J,Turnlund MW,Nguyen AP,Kenyon NJ,Davis CE

更新日期：2020-07-21 00:00:00

abstract：:In this work, we present a hydrophilic self-cleaning condenser surface for the collection of biological and environmental aerosol samples. The condenser is installed in a battery-operated hand-held breath sampling device. The device performance is characterized by the collection and analysis of exhaled breath samples ...

journal_title：Journal of breath research

authors： Zamuruyev KO,Schmidt AJ,Borras E,McCartney MM,Schivo M,Kenyon NJ,Delplanque JP,Davis CE

更新日期：2018-06-08 00:00:00

abstract：:Concentrations of exhaled volatile organic compounds (VOCs) may depend not only on biochemical or pathologic processes but also on physiological parameters. As breath sampling may be done in different body positions, effects of the sampling position on exhaled VOC concentrations were investigated by means of real-time...

journal_title：Journal of breath research

authors： Sukul P,Trefz P,Kamysek S,Schubert JK,Miekisch W

更新日期：2015-11-19 00:00:00

abstract：:Breath gas analysis provides insight into human metabolism of healthy and ill individuals. As an innovative and non-invasive method, it opens up options to improve diagnostics, monitoring and treatment decisions. Mid-infrared laser absorption spectroscopy is utilized to detect CH(4), H(2)O, CO(2), NH(3) and CH(3)OH in...

journal_title：Journal of breath research

authors： Hannemann M,Antufjew A,Borgmann K,Hempel F,Ittermann T,Welzel S,Weltmann KD,Völzke H,Röpcke J

更新日期：2011-06-01 00:00:00

abstract：:Radiation dose is important in radiotherapy. Too little, and the treatment is not effective, too much causes radiation toxicity. A biochemical measurement of the effect of radiotherapy would be useful in personalisation of this treatment. This study evaluated changes in exhaled breath volatile organic compounds (VOC) ...

journal_title：Journal of breath research

authors： Salman D,Eddleston M,Darnley K,Nailon WH,McLaren DB,Hadjithelki A,Ruszkiewicz D,Langejuergen J,Alkhalifa Y,Phillips I,Thomas CLP

更新日期：2020-10-24 00:00:00

abstract：:Wheeze is a common symptom in preschool children. The role of bacteria, regulatory T (T(reg)) cells and their association with airway inflammation in preschool wheeze is largely unknown. We evaluated inflammatory markers in exhaled breath condensate (EBC), bacterial colonization and circulating T(reg) cells in prescho...

journal_title：Journal of breath research

authors： van de Kant KD,Klaassen EM,van Aerde KJ,Damoiseaux J,Bruggeman CA,Stelma FF,Stobberingh EE,Muris JW,Jöbsis Q,van Schayck OC,Dompeling E

更新日期：2012-12-01 00:00:00

abstract：:Exhaled NO (FE(NO)) measurements have been utilized as a marker to diagnose asthma as well as a non-invasive tool for monitoring airway inflammation and the response to anti-inflammatory medications. One area where this non-invasive monitoring may be helpful is for asthmatic athletes as they train for competitive even...

journal_title：Journal of breath research

authors： Grob NM,Laskowski D,Dweik RA

更新日期：2008-09-01 00:00:00

abstract：:Blood ammonia is routinely used in clinical settings to assess systemic ammonia in hepatic encephalopathy and urea cycle disorders. Despite its drawbacks, blood measurement is often used as a comparator in breath studies because it is a standard clinical test. We sought to evaluate sources of measurement error and pot...

journal_title：Journal of breath research

authors： Spacek LA,Mudalel M,Tittel F,Risby TH,Solga SF

更新日期：2015-12-14 00:00:00