当前位置： SCI文献检索 > ANNALS OF SURGICAL ONCOLOGY期刊下所有文献 > Dynamics of FLAIR Volume Changes in Glioblastoma and Prediction of Survival.

Dynamics of FLAIR Volume Changes in Glioblastoma and Prediction of Survival.

Abstract：

BACKGROUND:The extent of tumor resection (EOTR) calculated by enhanced T1 changes in glioblastomas has been previously reported to predict survival. However, fluid-attenuated inversion recovery (FLAIR) volume may better represent tumor burden. In this study, we report the first assessment of the dynamics of FLAIR volume changes over time as a predictive variable for post-resection overall survival (OS). METHODS:Contemporary data from 103 consecutive patients with complete imaging and clinical data who underwent resection of newly diagnosed glioblastoma followed by the Stupp protocol between 2010 and 2013 were analyzed. Clinical, radiographic, and outcome parameters were retrieved for each patient, including magnetic resonance imaging (MRI)-based volumetric tumor analysis before, immediately after, and 3 months post-surgery. RESULTS:OS rate was 17.6 months. A significant incremental OS advantage was noted, with as little as 85 % T1-weighted gadolinium-enhanced (T1Gd)-EOTR measured on contrast-enhanced MRI. Pre- and immediate postoperative FLAIR-based EOTR was not predictive of OS; however, abnormal FLAIR volume measured 3 months post-surgery correlated significantly with outcome when FLAIR residual tumor volume (RTV) was <19.3 cm3 and <46 % of baseline volume (p < 0.0001 for both). Age and isocitrate dehydrogenase (IDH)-1 mutation were predictive of OS (p < 0.0001, Cox proportional hazards). CONCLUSIONS:OS correlated with the immediate postoperative T1Gd-EOTR measured by enhanced T1 MRI, but not by FLAIR volume. Diminished abnormal FLAIR volume at 3 months post-surgery was associated with OS benefit when FLAIR-RTV was <19.3 cm3 or <46 % of baseline. These threshold values provide a new radiological variable that can be used for prediction of OS in patients with glioblastoma immediately after completion of standard chemoradiation.

journal_name

Ann Surg Oncol

journal_title

Annals of surgical oncology

authors

Grossman R,Shimony N,Shir D,Gonen T,Sitt R,Kimchi TJ,Harosh CB,Ram Z

doi

10.1245/s10434-016-5635-z

subject

Has Abstract

pub_date

2017-03-01 00:00:00

pages

794-800

issue

3

eissn

1068-9265

issn

1534-4681

pii

10.1245/s10434-016-5635-z

journal_volume

24

pub_type

杂志文章

相关文献

ANNALS OF SURGICAL ONCOLOGY文献大全
  • Preoperative Tumor Markers Independently Predict Survival in Stage III Gastric Cancer Patients: Should We Include Tumor Markers in AJCC Staging?

    abstract：OBJECTIVE:The aim of this study was to determine the prognostic significance of preoperative carcinoembryonic antigen (CEA) and carbohydrate antigen (CA) 19-9 levels in patients with resectable gastric cancer (GC). PATIENTS AND METHODS:Patients who underwent a radical resection for GC at the Fujian Medical University ...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-018-6634-z

    authors： Lin JX,Wang W,Lin JP,Xie JW,Wang JB,Lu J,Chen QY,Cao LL,Lin M,Tu R,Zheng CH,Huang CM,Zhou ZW,Li P

    更新日期：2018-09-01 00:00:00

  • Should adjuvant therapy remain the standard of care for patients with resected adenocarcinoma of the pancreas?

    abstract：:Adenocarcinoma of the pancreas continues to be a formidable disease. In the United States, patients who have had resected disease are generally offered adjuvant chemoradiation. The current National Comprehensive Cancer Network practice guidelines uniformly support this practice. We reviewed seven selected series to ev...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,评审

    doi：10.1245/aso.2003.06.015

    authors： Chu QD,Khushalani N,Javle MM,Douglass HO Jr,Gibbs JF

    更新日期：2003-06-01 00:00:00

  • A comparison of clinical and pathologic assessments for the prediction of occult nipple involvement in nipple-sparing mastectomies.

    abstract：BACKGROUND:Nipple-sparing mastectomy (NSM) for both risk reduction and cancer is increasing. In the cancer setting, most studies suggest the use of both clinical and intraoperative biopsy criteria in patient selection. This study examines the use of both biopsy and clinical criteria in women undergoing total nipple-rem...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-012-2511-3

    authors： Stolier A,Stone JC,Moroz K,Hanemann CW,McNabb L,Jones SD,Lacey M

    更新日期：2013-01-01 00:00:00

  • ASO Author Reflections: Cytoreduction for Extrahepatic Metastatic Neuroendocrine Tumors.

    abstract：: ...

    journal_title：Annals of surgical oncology

    pub_type： 评论,杂志文章

    doi：10.1245/s10434-018-6885-8

    authors： Chan DL,Hallet J

    更新日期：2018-12-01 00:00:00

  • Role of Sentinel Lymph Node Biopsy in Microinvasive Breast Cancer.

    abstract：BACKGROUND:Microinvasive ductal carcinoma (DCISM), defined as DCIS with a focus of invasive carcinoma ≤ 1 mm, can be managed similarly to pure DCIS; however, management of the axilla in DCISM has been a subject of debate. Reports in the literature differ on the utility and necessity of sentinel lymph node biopsy (SLNB)...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-020-08606-3

    authors： Fan B,Pardo JA,Serres S,Alapati AC,Szewczyk J,Mele A,James TA

    更新日期：2020-10-01 00:00:00

  • Preoperative capecitabine and concurrent radiation for borderline resectable pancreatic cancer.

    abstract：BACKGROUND:Patients with borderline resectable pancreatic ductal adenocarcinoma (PDA) represent a high-risk group of patients due to tumor or patient-related characteristics. The optimal management of these patients has not been fully defined. MATERIALS AND METHODS:All patients undergoing evaluation for PDA between 20...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-010-1456-7

    authors： Stokes JB,Nolan NJ,Stelow EB,Walters DM,Weiss GR,de Lange EE,Rich TA,Adams RB,Bauer TW

    更新日期：2011-03-01 00:00:00

  • Current Delivery of Hyperthermic Intraperitoneal Chemotherapy with Cytoreductive Surgery (CS/HIPEC) and Perioperative Practices: An International Survey of High-Volume Surgeons.

    abstract：BACKGROUND:Cytoreductive surgery and heated intraperitoneal chemotherapy (CS/HIPEC) is performed for selected indications at a limited number of specialized centers worldwide. Currently there is no standardized approach to the perioperative care process. We sought to capture current practices in the perioperative manag...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-016-5692-3

    authors： Maciver AH,Al-Sukhni E,Esquivel J,Skitzki JJ,Kane JM 3rd,Francescutti VA

    更新日期：2017-04-01 00:00:00

  • Accurate lymph node staging is of greater prognostic importance than subclassification of the T2 category for gastric adenocarcinoma.

    abstract：BACKGROUND:Examination of 15 or more lymph nodes is necessary for accurate staging of gastric adenocarcinoma. This study examined whether prognostic discrimination is improved by distinguishing between pT2 tumors limited to the muscularis propria (MP) and those extending to subserosa (SS). METHODS:A single-institution...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/aso.2003.09.009

    authors： Sarela AI,Turnbull AD,Coit DG,Klimstra D,Brennan MF,Karpeh MS

    更新日期：2003-08-01 00:00:00

  • The Significance of CD44 Variant 9 in Resected Lung Adenocarcinoma: Correlation with Pathological Early-Stage and EGFR Mutation.

    abstract：BACKGROUND:CD44 isoforms serve as a marker for cancer stem cells. CD44 variant 9 (CD44v9) contributes to the defense against reactive oxygen species, resulting in resistance to chemoradiotherapy. However, the significance of CD44v9 in patients with lung adenocarcinoma is unknown. METHODS:We used immunohistochemical an...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-018-07137-2

    authors： Akamine T,Tagawa T,Ijichi K,Toyokawa G,Takamori S,Hirai F,Okamoto T,Oda Y,Maehara Y

    更新日期：2019-05-01 00:00:00

  • Is FGFR2 a Suitable Target to Treat Scirrhous-Type Gastric Cancer?

    abstract：: ...

    journal_title：Annals of surgical oncology

    pub_type： 社论

    doi：10.1245/s10434-018-07146-1

    authors： Yasui W

    更新日期：2019-04-01 00:00:00

  • Defining the Safety Profile for Performing Pancreatoduodenectomy in the Setting of Hyperbilirubinemia.

    abstract：BACKGROUND:Hyperbilirubinemia is commonly observed in patients requiring pancreatoduodenectomy (PD). Thus far, literature regarding the danger of operating in the setting of hyperbilirubinemia is equivocal. What remains undefined is at what specific level of bilirubin there is an adverse safety profile for undergoing P...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-019-08044-w

    authors： Chen B,Trudeau MT,Maggino L,Ecker BL,Keele LJ,DeMatteo RP,Drebin JA,Fraker DL,Lee MK 4th,Roses RE,Vollmer CM Jr

    更新日期：2020-05-01 00:00:00

  • Lymphatic drainage patterns from the treated breast.

    abstract：INTRODUCTION:Lymphatic drainage patterns from the breast have been described in the past. Drainage may change after treatment of a breast or axilla, and this may have implications for lymphatic mapping. The aim of this study was to determine the lymphatic drainage patterns in breast cancer patients with a previously tr...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-009-0841-6

    authors： van der Ploeg IM,Oldenburg HS,Rutgers EJ,Baas-Vrancken Peeters MJ,Kroon BB,Valdés Olmos RA,Nieweg OE

    更新日期：2010-04-01 00:00:00

  • Relevance of Dissection of the Posterior Superior Pancreaticoduodenal Lymph Nodes in Gallbladder Carcinoma.

    abstract：BACKGROUND:This study was designed to evaluate the prognostic value of positive posterior superior pancreaticoduodenal lymph nodes to clarify the need for dissection of these nodes. METHODS:A total of 148 patients with gallbladder carcinoma who underwent radical resection including dissection of the posterior superior...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-017-5939-7

    authors： Sakata J,Kobayashi T,Tajima Y,Ohashi T,Hirose Y,Takano K,Takizawa K,Miura K,Wakai T

    更新日期：2017-09-01 00:00:00

  • Is total mesorectal excision always necessary for T1-T2 lower rectal cancer?

    abstract：BACKGROUND:The goal of this multicenter study was to clarify the determinants of local excision for patients with T1-T2 lower rectal cancer. METHODS:Data from 567 consecutive patients who underwent radical resection for T1-T2 lower rectal cancer at 12 institutions between 1991 and 1998 were reviewed. Rates of lymph no...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,多中心研究

    doi：10.1245/s10434-009-0849-y

    authors： Kobayashi H,Mochizuki H,Kato T,Mori T,Kameoka S,Shirouzu K,Saito Y,Watanabe M,Morita T,Hida J,Ueno M,Ono M,Yasuno M,Sugihara K

    更新日期：2010-04-01 00:00:00

  • Cholangiocarcinoma Heterogeneity Revealed by Multigene Mutational Profiling: Clinical and Prognostic Relevance in Surgically Resected Patients.

    abstract：BACKGROUND:Cholangiocarcinoma can be classified in intrahepatic cholangiocarcinoma (ICC) and perihilar cholangiocarcinoma (PCC). Moreover, PCC includes two different forms: extrahepatic (EH) PCC, which arises from the perihilar EH large ducts, and intrahepatic (IH) PCC, in which a significant liver mass invades the per...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-015-5046-6

    authors： Ruzzenente A,Fassan M,Conci S,Simbolo M,Lawlor RT,Pedrazzani C,Capelli P,D'Onofrio M,Iacono C,Scarpa A,Guglielmi A

    更新日期：2016-05-01 00:00:00

  • Prospective study of outcomes after percutaneous biliary drainage for malignant biliary obstruction.

    abstract：BACKGROUND:Percutaneous biliary drainage (PBD) is used to relieve malignant bile duct obstruction (MBO) when endoscopic drainage is not feasible. Little is known about the effects of PBD on the quality of life (QoL) in patients with MBO. The aim of this study was to evaluate changes in QoL and pruritus after PBD and to...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-010-1045-9

    authors： Robson PC,Heffernan N,Gonen M,Thornton R,Brody LA,Holmes R,Brown KT,Covey AM,Fleischer D,Getrajdman GI,Jarnagin W,Sofocleous C,Blumgart L,D'Angelica M

    更新日期：2010-09-01 00:00:00

  • Identification of the NEDD4L gene as a prognostic marker by integrated microarray analysis of copy number and gene expression profiling in non-small cell lung cancer.

    abstract：PURPOSE:The purpose of this study was to identify prognostic genes by integrated microarray analysis between comparative genomic hybridization and gene expression with laser microdissection in non-small cell lung cancer (NSCLC). METHODS:Integrated microarray analysis in 11 lung adenocarcinomas was performed, and sever...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-013-3059-6

    authors： Sakashita H,Inoue H,Akamine S,Ishida T,Inase N,Shirao K,Mori M,Mimori K

    更新日期：2013-12-01 00:00:00

  • The Landmark Series: Minimally Invasive Surgery for Cervical Cancer.

    abstract：:Cervical cancer incidence and mortality have declined in developed countries during the past few decades as a result of screening programs and vaccination. However, it remains a significant cause of cancer-related mortality in young women. Early-stage cervical cancer, defined as disease limited to the cervix, has trad...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-020-09265-0

    authors： Basaran D,Leitao MM Jr

    更新日期：2021-01-01 00:00:00

  • Comparison of Multiple Wire, Radioactive Seed, and Savi Scout® Radar Localizations for Management of Surgical Breast Disease.

    abstract：BACKGROUND:Radioactive seed localization (RSL) and the Savi Scout® radar (SSR) are newer alternatives to wire-guided localization (WL) for nonpalpable breast lesions. OBJECTIVE:The aim of this study was to compare three localization devices when multiple devices were used for preoperative localization for breast surge...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-020-09159-1

    authors： Srour MK,Kim S,Amersi F,Giuliano AE,Chung A

    更新日期：2020-09-28 00:00:00

  • Suppression of beta-catenin by antisense oligomers augments tumor response to isolated limb perfusion in a rodent model of adenomatous polyposis coli-mutant colon cancer.

    abstract：BACKGROUND:Isolated hepatic perfusion has been used in patients with colorectal cancer (CRC) metastatic to the liver. We sought to determine whether perfusion with antisense oligodeoxynucleotides results in the downregulation of beta-catenin and whether this improves tumor response to isolated limb perfusion (ILP) in a...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/ASO.2005.10.005

    authors： Canter RJ,Kesmodel SB,Heitjan DF,Veeramachaneni NK,Mokadam NA,Drebin JA,Fraker DL

    更新日期：2005-09-01 00:00:00

  • The Suggestion of Revised Criteria for Endoscopic Resection of Differentiated-Type Submucosal Gastric Cancer.

    abstract：BACKGROUND:Early gastric cancer that meets the expanded criteria for endoscopic resection (ER) is expected to be associated with a negligible risk for lymph node metastasis (LNM); however, recent studies have reported LNM in submucosal gastric cancer patients who met the existing criteria. In this study, we develop the...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,多中心研究

    doi：10.1245/s10434-019-08102-3

    authors： Ma DW,Lee SJ,Kook MC,Park DY,Ahn S,Ryu KW,Choi IJ,Noh SH,Kim H,Lee YC,Kim JH

    更新日期：2020-03-01 00:00:00

  • Water: a simple solution for tumor spillage.

    abstract：BACKGROUND:Although often proposed as a means to reduce the harmful consequences of tumor spill, water lavage has yet to be systematically evaluated in relevant in vitro and in vivo models. This study evaluates the mechanisms and utility of a single water lavage to improve the sequelae of tumor spill during laparotomy....

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-011-1588-4

    authors： Ito F,Camoriano M,Seshadri M,Evans SS,Kane JM 3rd,Skitzki JJ

    更新日期：2011-08-01 00:00:00

  • Outcomes and Risk Score for Distal Pancreatectomy with Celiac Axis Resection (DP-CAR): An International Multicenter Analysis.

    abstract：BACKGROUND:Distal pancreatectomy with celiac axis resection (DP-CAR) is a treatment option for selected patients with pancreatic cancer involving the celiac axis. A recent multicenter European study reported a 90-day mortality rate of 16%, highlighting the importance of patient selection. The authors constructed a risk...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章,多中心研究

    doi：10.1245/s10434-018-07101-0

    authors： Klompmaker S,Peters NA,van Hilst J,Bassi C,Boggi U,Busch OR,Niesen W,Van Gulik TM,Javed AA,Kleeff J,Kawai M,Lesurtel M,Lombardo C,Moser AJ,Okada KI,Popescu I,Prasad R,Salvia R,Sauvanet A,Sturesson C,Weiss MJ,Zeh

    更新日期：2019-03-01 00:00:00

  • Differences in Metastatic Pattern in Patients Presenting With or Without Obstructing Colorectal Cancer: A Retrospective Observational Study of 2595 Patients.

    abstract：BACKGROUND:Little is known about metastatic patterns in patients with obstructing colorectal cancer (CRC). OBJECTIVE:The aim of this study was to determine if metastatic patterns in patients with CRC differ between patients with or without obstruction. METHODS:This single-center, observational, retrospective cohort s...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-019-08119-8

    authors： Boeding JRE,Ramphal W,Crolla RMPH,Gobardhan PD,Schreinemakers JMJ

    更新日期：2020-04-01 00:00:00

  • Involvement of CD40 targeting miR-224 and miR-486 on the progression of pancreatic ductal adenocarcinomas.

    abstract：BACKGROUND:Genetic and epigenetic alterations during development of pancreatic ductal adenocarcinomas (PDAC) are well known. Genetic and epigenetic data were correlated with tumor biology to find specific alterations responsible for invasion and metastasis in pancreatic ductal adenocarcinomas. METHODS:A total of 16 hu...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-009-0531-4

    authors： Mees ST,Mardin WA,Sielker S,Willscher E,Senninger N,Schleicher C,Colombo-Benkmann M,Haier J

    更新日期：2009-08-01 00:00:00

  • Uptake and patient outcomes of laparoscopic colon and rectal cancer surgery in a publicly funded system and following financial incentives.

    abstract：PURPOSE:To assess patterns of uptake and outcomes of laparoscopic colon and rectal cancer surgery in Ontario, and the potential influence of surgical fee incentives instituted on October 1, 2005. METHODS:We used Ontario administrative databases from fiscal years 2002 to 2009. Study outcomes were uptake rates of laparo...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-013-3123-2

    authors： Simunovic M,Baxter NN,Sutradhar R,Liu N,Cadeddu M,Urbach D

    更新日期：2013-11-01 00:00:00

  • Impact of a temporary stoma on the quality of life of rectal cancer patients undergoing treatment.

    abstract：BACKGROUND:Data from randomized controlled trials support use of a diverting stoma in rectal cancer patients with low anastomoses, but there is little data on how this impacts patient quality of life (QOL). This study prospectively evaluates QOL in stage I-III rectal cancer patients undergoing sphincter-preserving surg...

    journal_title：Annals of surgical oncology

    pub_type： 临床试验,杂志文章

    doi：10.1245/s10434-010-1446-9

    authors： Neuman HB,Patil S,Fuzesi S,Wong WD,Weiser MR,Guillem JG,Paty PB,Nash GM,Temple LK

    更新日期：2011-05-01 00:00:00

  • Verification of musculoskeletal FDG-PET-CT findings performed for melanoma staging.

    abstract：BACKGROUND:The purpose of this study is to establish the validity of F-18-deoxyglucose positron emission tomography-computed tomography (FDG-PET-CT) scan staging for cutaneous melanoma when a musculoskeletal image abnormality is detected. METHODS:An institutional review board (IRB)-approved prospective database was qu...

    journal_title：Annals of surgical oncology

    pub_type： 临床试验,杂志文章

    doi：10.1245/s10434-009-0843-4

    authors： Mansour AA 3rd,Kelley MC,Hatmaker AR,Holt GE,Schwartz HS

    更新日期：2010-04-01 00:00:00

  • Aggressive Hemihepatectomy Combined with Resection and Reconstruction of Middle Hepatic Vein for Intrahepatic Cholangiocarcinoma.

    abstract：BACKGROUND:Major hepatectomy for intrahepatic cholangiocarcinoma (ICC) sometimes involves resection of major hepatic veins, which might result in the future liver remnant (FLR) congestion. The necessity and efficacy of resection and reconstruction of the middle hepatic vein (MHV) during right or left hemihepatectomy fo...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-016-5384-z

    authors： Miyata A,Sakamoto Y,Yamamoto S,Akamatsu N,Arita J,Kaneko J,Hasegawa K,Kokudo N

    更新日期：2016-08-01 00:00:00

  • Long-term outcome of patients with complete pathologic response after neoadjuvant chemoradiation for cT3 rectal cancer: implications for local excision surgical strategies.

    abstract：BACKGROUND:Neoadjuvant chemoradiotherapy (CRT) followed by radical surgery including total mesorectal excision (TME) is standard treatment in patients with locally advanced rectal cancer. Emerging data indicate that patients with complete pathologic response (ypCR) after CRT have favorable outcome, suggesting the possi...

    journal_title：Annals of surgical oncology

    pub_type： 杂志文章

    doi：10.1245/s10434-011-1822-0

    authors： Belluco C,De Paoli A,Canzonieri V,Sigon R,Fornasarig M,Buonadonna A,Boz G,Innocente R,Perin T,Cossaro M,Polesel J,De Marchi F

    更新日期：2011-12-01 00:00:00