Relevance of Dissection of the Posterior Superior Pancreaticoduodenal Lymph Nodes in Gallbladder Carcinoma.

Abstract:

BACKGROUND:This study was designed to evaluate the prognostic value of positive posterior superior pancreaticoduodenal lymph nodes to clarify the need for dissection of these nodes. METHODS:A total of 148 patients with gallbladder carcinoma who underwent radical resection including dissection of the posterior superior pancreaticoduodenal nodes were enrolled. The incidence of metastasis and the survival rates among patients with metastasis to each lymph node group were calculated. RESULTS:Of the 148 patients, 70 (47%) had nodal disease. The incidences of metastasis in the cystic duct, pericholedochal, retroportal, and hepatic artery node groups, defined as regional nodes in the UICC TNM staging system, ranged from 8.3 to 24.3% with 5-year survival rates of 12.5-46.4% in patients with positive nodes. The incidence of metastasis to the posterior superior pancreaticoduodenal nodes was 12.8% with a 5-year survival rate of 31.6% in patients with positive nodes. Survival after resection was significantly better in patients with distant nodal disease affecting only the posterior superior pancreaticoduodenal nodes (5-year survival, 55.6%) than in patients with distant nodal disease beyond these nodes (5-year survival, 15.0%; p = 0.046), whereas survival after resection was comparable between the former group and patients with regional nodal disease alone (5-year survival, 40.7%; p = 0.426). CONCLUSIONS:In gallbladder carcinoma, involvement of the posterior superior pancreaticoduodenal nodes is similar to that of regional nodes in terms of both the incidence of metastasis and the impact on survival. Inclusion of the posterior superior pancreaticoduodenal nodes among the regional nodes should be considered.

journal_name

Ann Surg Oncol

authors

Sakata J,Kobayashi T,Tajima Y,Ohashi T,Hirose Y,Takano K,Takizawa K,Miura K,Wakai T

doi

10.1245/s10434-017-5939-7

subject

Has Abstract

pub_date

2017-09-01 00:00:00

pages

2474-2481

issue

9

eissn

1068-9265

issn

1534-4681

pii

10.1245/s10434-017-5939-7

journal_volume

24

pub_type

杂志文章
  • Effect of growth hormone on tumor and host in an animal model.

    abstract:BACKGROUND:The relative effects of growth hormone on tumor versus host growth and protein metabolism are not known. This study examines the influence of recombinant rat growth hormone (r-rGH) on host and tumor growth, host body composition, and protein synthesis of tumor and host in tumor-bearing rats. METHODS:After l...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1007/BF02303570

    authors: Wolf RF,Ng B,Weksler B,Burt M,Brennan MF

    更新日期:1994-07-01 00:00:00

  • Treatment of Diaphragmatic Hernia Occurring After Transhiatal Esophagectomy.

    abstract:BACKGROUND:Postesophagectomy diaphragmatic hernia (DH) is an uncommon problem but an important one to recognize and treat because of the risk of significant complications such as incarceration and strangulation. Diaphragmatic hernia appears to occur more frequently following transhiatal esophagectomy (THE) than after t...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-015-4366-x

    authors: Narayanan S,Sanders RL,Herlitz G,Langenfeld J,August DA

    更新日期:2015-10-01 00:00:00

  • Routine screening for local recurrence following breast-conserving therapy for cancer with dynamic contrast-enhanced magnetic resonance imaging of the breast.

    abstract:BACKGROUND:Dynamic contrast-enhanced magnetic resonance imaging (MRI) of the breast is highly sensitive for the diagnosis of primary breast malignancy. We investigated the clinical application of dedicated dynamic breast MR for routine screening for local recurrence following breast-conserving therapy. METHODS:Patient...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1007/BF02303784

    authors: Drew PJ,Kerin MJ,Turnbull LW,Imrie M,Carleton PJ,Fox JN,Monson JR

    更新日期:1998-04-01 00:00:00

  • Adverse outcomes associated with noncompliance with melanoma treatment guidelines.

    abstract:BACKGROUND:Clinical practice guidelines have been developed to improve melanoma patient care. However, it is unclear whether failure to comply with these standards (either excessive or inadequate treatment) increases morbidity or relapse rates. Therefore, we undertook this study to evaluate the effect of variance from ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-008-0021-0

    authors: Erickson Foster J,Velasco JM,Hieken TJ

    更新日期:2008-09-01 00:00:00

  • Laparoscopic abdominoperineal resection with open posterior cylindrical excision and primary transpelvic VRAM flap.

    abstract:BACKGROUND:In our own experience over the last 15 years, the primary transpelvic vertical rectus abdominis myocutaneous (VRAM) flap is a reliable tool to prevent perineal wound complications after cylindrical excision in radical anorectal tumor surgery. To minimize the operative trauma in such patients, we performed a ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-011-1977-8

    authors: Horch RE,D'Hoore A,Holm T,Kneser U,Hohenberger W,Arkudas A

    更新日期:2012-02-01 00:00:00

  • Nephrectomy during operative management of retroperitoneal sarcoma.

    abstract:BACKGROUND:Complete resection of a retroperitoneal sarcoma often requires removal of adjacent organs. In this study we evaluated the role of nephrectomy during operation for retroperitoneal sarcoma. METHODS:Between July 1982 and July 1995, 75 of the 371 (20%) patients who underwent resection of retroperitoneal sarcoma...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1007/BF02305556

    authors: Russo P,Kim Y,Ravindran S,Huang W,Brennan MF

    更新日期:1997-07-01 00:00:00

  • Intra-operative sonography: a valuable aid during breast-conserving surgery for occult breast cancer.

    abstract:BACKGROUND:Breast cancer is increasingly detected during an early non-palpable stage. Together with pre-operative marking of the mass, intra-operative imaging provides invaluable clues. This study was designed to evaluate the usefulness of intra-operative sonography in the hands of the surgeon. METHODS:Between July 20...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-007-9490-9

    authors: Haid A,Knauer M,Dunzinger S,Jasarevic Z,Köberle-Wührer R,Schuster A,Toeppker M,Haid B,Wenzl E,Offner F

    更新日期:2007-11-01 00:00:00

  • Outcomes in Peritoneal Carcinomatosis from Appendiceal Goblet Cell Carcinoma Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS/HIPEC).

    abstract:BACKGROUND:Appendiceal goblet cell adenocarcinoma (GCA) is often misclassified and mistreated due to mixed histologic features. In general, cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) is standard of care for peritoneal carcinomatosis (PC) from mucinous appendiceal tumors; however, i...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-019-07932-5

    authors: Zambrano-Vera K,Sardi A,Munoz-Zuluaga C,Studeman K,Nieroda C,Sittig M,King MC,Sipok A,Gushchin V

    更新日期:2020-01-01 00:00:00

  • The Landmark Series: Neuroendocrine Tumor Liver Metastases.

    abstract:BACKGROUND:Neuroendocrine tumors are becoming increasingly prevalent, with many patients presenting with or developing metastatic disease to the liver. METHODS:In this landmark series paper, we highlight the critical studies that have defined the surgical management of neuroendocrine tumor liver metastases, as well as...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1245/s10434-020-08787-x

    authors: Gangi A,Howe JR

    更新日期:2020-09-01 00:00:00

  • Pleomorphic Lobular Carcinoma In Situ: Radiologic-Pathologic Features and Clinical Management.

    abstract:BACKGROUND:Pleomorphic lobular carcinoma in situ (PLCIS) is an unusual variant of LCIS for which optimal management remains unclear. METHODS:We conducted a 15-year (2000-2014) retrospective chart review of the radiologic, pathologic, clinical management, and recurrence rates of patients with PLCIS on diagnostic biopsy...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-015-4552-x

    authors: Flanagan MR,Rendi MH,Calhoun KE,Anderson BO,Javid SH

    更新日期:2015-12-01 00:00:00

  • Percutaneous Preoperative Biliary Drainage for Resectable Perihilar Cholangiocarcinoma: No Association with Survival and No Increase in Seeding Metastases.

    abstract:BACKGROUND:Endoscopic biliary drainage (EBD) and percutaneous transhepatic biliary drainage (PTBD) are both used to resolve jaundice before surgery for perihilar cholangiocarcinoma (PHC). PTBD has been associated with seeding metastases. The aim of this study was to compare overall survival (OS) and the incidence of in...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-015-4676-z

    authors: Wiggers JK,Groot Koerkamp B,Coelen RJ,Doussot A,van Dieren S,Rauws EA,Schattner MA,van Lienden KP,Brown KT,Besselink MG,van Tienhoven G,Allen PJ,Busch OR,D'Angelica MI,DeMatteo RP,Gouma DJ,Kingham TP,Verheij J,Jarnagi

    更新日期:2015-12-01 00:00:00

  • Impact of Patient Age on the Postoperative Survival in Pancreatic Head Cancer.

    abstract:BACKGROUND:Some reports have stated that pancreatoduodenectomy for elderly patients have comparable morbidity and mortality to that of young patients. However, the long-term outcomes of these patients have not been fully evaluated, especially for pancreatic head cancer. METHODS:A total of 227 patients who underwent pa...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-017-5994-0

    authors: Sugiura T,Okamura Y,Ito T,Yamamoto Y,Ashida R,Uesaka K

    更新日期:2017-10-01 00:00:00

  • Outcomes of Breast Cancer Patients Treated with Accelerated Partial Breast Irradiation Via Multicatheter Interstitial Brachytherapy: The Pooled Registry of Multicatheter Interstitial Sites (PROMIS) Experience.

    abstract:PURPOSE:To report outcomes for breast-conserving therapy using adjuvant accelerated partial breast irradiation with interstitial multicatheter brachytherapy by a cooperative group of institutions. METHODS:From 1992 to 2013, a total of 1356 patients were treated with breast-conserving surgery and adjuvant accelerated p...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-015-4563-7

    authors: Kamrava M,Kuske RR,Anderson B,Chen P,Hayes J,Quiet C,Wang PC,Veruttipong D,Snyder M,Jeffrey Demanes D

    更新日期:2015-12-01 00:00:00

  • Comparison of Multiple Wire, Radioactive Seed, and Savi Scout® Radar Localizations for Management of Surgical Breast Disease.

    abstract:BACKGROUND:Radioactive seed localization (RSL) and the Savi Scout® radar (SSR) are newer alternatives to wire-guided localization (WL) for nonpalpable breast lesions. OBJECTIVE:The aim of this study was to compare three localization devices when multiple devices were used for preoperative localization for breast surge...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-020-09159-1

    authors: Srour MK,Kim S,Amersi F,Giuliano AE,Chung A

    更新日期:2020-09-28 00:00:00

  • Phosphatase and tensin analog gene overexpression engenders cellular death in human malignant mesothelioma cells via inhibition of AKT phosphorylation.

    abstract:BACKGROUND:Abnormal phosphatase and tensin analog (PTEN) gene expression has been noted in neoplasms. The PTEN protein cleaves phosphate groups from cellular growth kinases, inhibiting tumor propagation. A downstream target of PTEN is AKT, a serine-threonine kinase that when activated inhibits apoptosis. We sought to d...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1007/BF02573071

    authors: Mohiuddin I,Cao X,Ozvaran MK,Zumstein L,Chada S,Smythe WR

    更新日期:2002-04-01 00:00:00

  • The association of surgical margins and local recurrence in women with early-stage invasive breast cancer treated with breast-conserving therapy: a meta-analysis.

    abstract:PURPOSE:There is no consensus on what constitutes adequate negative margins in breast-conserving therapy (BCT). We systematically review the evidence on surgical margins in BCT for invasive breast cancer to support the development of clinical guidelines. METHODS:Study-level meta-analysis of studies reporting local rec...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,meta分析

    doi:10.1245/s10434-014-3480-5

    authors: Houssami N,Macaskill P,Marinovich ML,Morrow M

    更新日期:2014-03-01 00:00:00

  • Nrf2 is useful for predicting the effect of chemoradiation therapy on esophageal squamous cell carcinoma.

    abstract:BACKGROUND:The transcription factor NF-E2-related factor 2 (Nrf2) was originally identified to be a critical regulator of intracellular antioxidants and phase II detoxification enzymes. Recent studies have shown that high Nrf2 expression gives cancer cells an advantage for survival from anticancer chemotherapy and radi...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-014-3600-2

    authors: Kawasaki Y,Okumura H,Uchikado Y,Kita Y,Sasaki K,Owaki T,Ishigami S,Natsugoe S

    更新日期:2014-07-01 00:00:00

  • The Expression of Melanoma-Associated Antigen D2 Both in Surgically Resected and Serum Samples Serves as Clinically Relevant Biomarker of Gastric Cancer Progression.

    abstract:BACKGROUND:Sensitive biomarkers are necessary for risk classification of patients with gastric cancer (GC), especially ones at risk of distant metastases. Melanoma-associated antigen (MAGE)-D2 has been reported to play a role in the process of cell adhesion and metastatic potential of tumor cells in colorectal cancer. ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-015-4457-8

    authors: Kanda M,Nomoto S,Oya H,Takami H,Shimizu D,Hibino S,Hashimoto R,Kobayashi D,Tanaka C,Yamada S,Fujii T,Nakayama G,Sugimoto H,Koike M,Fujiwara M,Kodera Y

    更新日期:2016-02-01 00:00:00

  • Is there an optimal surgery time after endoscopic resection in early gastric cancer?

    abstract:BACKGROUND:The patients with early gastric cancer who have undergone incomplete endoscopic resection (ER) generally need additional surgery because of the possibility of lymph node metastasis. The aim of study was to evaluate the optimal time interval from ER to additive surgery by evaluating the effect of time interva...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-013-3299-5

    authors: Kim MJ,Kim JH,Lee YC,Kim JW,Choi SH,Hyung WJ,Noh SH,Youn YH,Park H,Lee SI

    更新日期:2014-01-01 00:00:00

  • Prediction of recurrence and survival by post-resection CA 19-9 values in patients with adenocarcinoma of the pancreas.

    abstract:BACKGROUND:CA 19-9 levels are useful for the diagnosis of patients with pancreatic adenocarcinoma. However, interest has recently turned toward its use as a prognostic indicator. The purpose of this study is to determine whether postoperative CA 19-9 levels predict disease-free survival (DFS) and median survival (MS) i...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1007/BF02305535

    authors: Montgomery RC,Hoffman JP,Riley LB,Rogatko A,Ridge JA,Eisenberg BL

    更新日期:1997-10-01 00:00:00

  • Hiatal Hernia After Open versus Minimally Invasive Esophagectomy: A Systematic Review and Meta-analysis.

    abstract::Hiatal hernia (HH) is an infrequent yet potentially life-threatening complication after esophagectomy. Several studies have reported the incidence of this complication after both open and minimally invasive esophagectomy (MIE). This meta-analysis aimed to determine the pooled incidence of HH after both types of esopha...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1245/s10434-016-5155-x

    authors: Oor JE,Wiezer MJ,Hazebroek EJ

    更新日期:2016-08-01 00:00:00

  • Anaplastic thyroid carcinoma: biology, pathogenesis, prognostic factors, and treatment approaches.

    abstract:BACKGROUND:Anaplastic thyroid carcinoma (ATC) is one of the most aggressive solid tumors known to affect humans and carries a dismal prognosis. Our primary aim was to review its epidemiology, biology, risk factors, and prognostic indicators. We also reviewed the individual and combined roles of surgery, radiotherapy, c...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章,评审

    doi:10.1245/ASO.2006.05.042

    authors: Are C,Shaha AR

    更新日期:2006-04-01 00:00:00

  • Preoperative capecitabine and concurrent radiation for borderline resectable pancreatic cancer.

    abstract:BACKGROUND:Patients with borderline resectable pancreatic ductal adenocarcinoma (PDA) represent a high-risk group of patients due to tumor or patient-related characteristics. The optimal management of these patients has not been fully defined. MATERIALS AND METHODS:All patients undergoing evaluation for PDA between 20...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-010-1456-7

    authors: Stokes JB,Nolan NJ,Stelow EB,Walters DM,Weiss GR,de Lange EE,Rich TA,Adams RB,Bauer TW

    更新日期:2011-03-01 00:00:00

  • Outcomes of Lymph Node Dissection for Non-metastatic Pancreatic Neuroendocrine Tumors: A Propensity Score-Weighted Analysis of the National Cancer Database.

    abstract:BACKGROUND:Although the National Comprehensive Cancer Network (NCCN) guidelines recommend use of lymph node dissection (LND) in patients with pancreatic neuroendocrine tumors (pNETs) > 2 cm, there is limited evidence to support the association between use of LND and overall survival (OS). METHODS:Patients with resecte...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-019-07506-5

    authors: Mao R,Zhao H,Li K,Luo S,Turner M,Cai JQ,Blazer D 3rd

    更新日期:2019-09-01 00:00:00

  • New metastatic lymph node ratio system reduces stage migration in patients undergoing D1 lymphadenectomy for gastric adenocarcinoma.

    abstract:BACKGROUND:The American Joint Committee on Cancer (AJCC)/International Union Against Cancer (UICC) staging system for gastric cancer incorporates the absolute number of metastatic lymph nodes (N status) and is optimally used when >or=15 nodes are examined. The ratio of metastatic to examined nodes (N ratio) is an effec...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-010-0914-6

    authors: Maduekwe UN,Lauwers GY,Fernandez-Del-Castillo C,Berger DL,Ferguson CM,Rattner DW,Yoon SS

    更新日期:2010-05-01 00:00:00

  • Annexin II overexpression predicts rapid recurrence after surgery in pancreatic cancer patients undergoing gemcitabine-adjuvant chemotherapy.

    abstract:BACKGROUND:Gemcitabine has been shown to exhibit significant clinical activity against pancreatic cancer and has become a first-line chemotherapeutic for this disease in recent years. However, there are still many patients who do not respond to this treatment and it is expected to improve the clinical outcome if we can...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-008-0061-5

    authors: Takano S,Togawa A,Yoshitomi H,Shida T,Kimura F,Shimizu H,Yoshidome H,Ohtsuka M,Kato A,Tomonaga T,Nomura F,Miyazaki M

    更新日期:2008-11-01 00:00:00

  • Oncologic Outcomes After Treatment for MRI Occult Breast Cancer (pT0N+).

    abstract:BACKGROUND:Studies assessing outcomes in occult breast cancer have often included women treated before the routine use of magnetic resonance imaging (MRI). This study examined outcomes for patients presenting with axillary adenopathy and no primary breast tumor detectable by MRI or other imaging methods. METHODS:All p...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-017-5965-5

    authors: McCartan DP,Zabor EC,Morrow M,Van Zee KJ,El-Tamer MB

    更新日期:2017-10-01 00:00:00

  • Conservative Re-excision is a Safe and Simple Alternative to Radical Resection in Revision Surgery for Dermatofibrosarcoma Protuberans.

    abstract:BACKGROUND:Dermatofibrosarcoma protuberans (DFSP) is a dermal sarcoma often diagnosed by excision biopsy, and is often incompletely excised, with high recurrence rates. Traditional wide excision involves resection margins of 2-4 cm, often resulting in morbid procedures requiring surgical reconstruction. An alternative ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-019-08011-5

    authors: Snow H,Davies E,Strauss DC,Smith M,Hayes AJ

    更新日期:2020-03-01 00:00:00

  • Survival data justifies resection for pancreatic metastases.

    abstract:BACKGROUND:Pancreatic metastases are uncommon and little is known about the oncologic outcome after resection or prognostic parameters. This study was designed to evaluate perioperative and follow-up results after resection for pancreatic metastases and to define prognostic factors. METHODS:From a prospective database...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-009-0682-3

    authors: Strobel O,Hackert T,Hartwig W,Bergmann F,Hinz U,Wente MN,Fritz S,Schneider L,Büchler MW,Werner J

    更新日期:2009-12-01 00:00:00

  • Influence of nonclinical factors on choice of therapy for early hepatocellular carcinoma.

    abstract:BACKGROUND:Initial therapy for early hepatocellular carcinoma (HCC) with well-compensated cirrhosis is controversial. While we previously reported on the effect of clinical factors and surgeon specialty on choice of therapy for early HCC, other nonclinical factors also may impact decision-making. METHODS:Surgeons who ...

    journal_title:Annals of surgical oncology

    pub_type: 杂志文章

    doi:10.1245/s10434-012-2619-5

    authors: Nathan H,Segev DL,Bridges JF,Massie AB,Cameron AM,Hirose K,Schulick RD,Choti MA,Pawlik TM

    更新日期:2013-02-01 00:00:00