Impact of pretransplant minimal residual disease on the post-transplant outcome of pediatric acute lymphoblastic leukemia.

abstract：:Despite the introduction of a variety of new immunosuppressive agents, cyclosporine A (CsA) has maintained a strong position in pediatric transplantation (Tx). Post-Tx dosing with CsA is a challenging task because of the narrow therapeutic window of the drug, the great individual variability of metabolism and the lack...

journal_title：Pediatric transplantation

authors： Seikku P,Hoppu K,Jalanko H,Holmberg C

更新日期：2003-04-01 00:00:00

abstract：:LI is a subset of the heterotaxy syndrome and a rare birth defect that involves the heart and other organs. It can be combined with extracardiac abnormalities, especially BA. CHD can be associated with LI in up to 15% of cases, although it is rare in BA. Pediatric LT for a child with ESLD due to BA combined with LI an...

journal_title：Pediatric transplantation

authors： Youn JK,Lee JM,Yi NJ,Choi YR,Suh SW,You T,Lee KW,Jung CW,Lee JW,Bae EJ,Ko JS,Kim WH,Park KW,Suh KS

更新日期：2014-12-01 00:00:00

abstract：:Tacrolimus-based immunosuppression in pediatric liver transplant recipients is known to be associated with EGID. Our goal was to determine the incidence, risk factors, and characteristics of EGID in our pediatric liver transplantation program. This study was a retrospective analysis of 38 pediatric liver transplant re...

journal_title：Pediatric transplantation

authors： Lee JH,Park HY,Choe YH,Lee SK,Lee SI

更新日期：2007-08-01 00:00:00

abstract：:Children receiving HCT loose protective immunity to vaccines received pre-HCT. Therefore, revaccination post-HCT is of major importance. In Denmark, a vaccination schedule with fewer doses post-HCT has been used, including two doses for diphtheria, tetanus, polio, measles, mumps, and rubella, and one dose only for Hae...

journal_title：Pediatric transplantation

authors： Jensen L,Poulsen A,Nygaard U,Scheike T,Riis MS,Pedersen FK,Heilmann C

更新日期：2020-02-01 00:00:00

abstract：:An increased frequency of infections has been reported in patients with chronic liver disease. The tendency of patients in this population to acquire UTI is not completely understood. We aimed at investigating the incidence of UTI in children with cirrhosis, before liver transplantation. Twenty-six children (9 girls, ...

journal_title：Pediatric transplantation

authors： Baskin E,Ozçay F,Sakalli H,Agras PI,Karakayali H,Canan O,Haberal M

更新日期：2007-06-01 00:00:00

abstract：:Although an LDLT can successfully treat biliary atresia (BA), some patients develop liver fibrosis or inflammation. To study the incidence and risk factors associated with these complications, we performed serial protocol biopsies. Twenty-four patients with BA who received a pediatric LDLT underwent protocol biopsies....

journal_title：Pediatric transplantation

authors： Ueno T,Tanaka N,Ihara Y,Takama Y,Yamada H,Mushiake S,Fukuzawa M

更新日期：2011-08-01 00:00:00

abstract：:Since December 1995, pediatric renal transplant recipients in our unit have received a DMSA scan as soon as possible post-transplant in order to provide a baseline for comparison in the event of subsequent complications. We retrospectively reviewed the case notes and DMSA scans of the 45 patients who underwent a scan ...

journal_title：Pediatric transplantation

authors： Hutchinson C,Beckett M,Kiratli P,Gordon I,Trompeter RS,Rees L

更新日期：2003-12-01 00:00:00

abstract：:Thrombosis after kidney transplantation may result in catastrophic outcomes, including graft loss. Thrombophilia has been implicated in post-transplant thrombosis; data, however, are inconclusive on the impact of acquired and inherited thrombophilia and resultant thrombosis in renal graft recipients. We aimed to evalu...

journal_title：Pediatric transplantation

authors： Bock ME,Bobrowski AE,Bhat R

更新日期：2019-02-01 00:00:00

abstract：:The adjusted relative risk (aRR) for development of post-transplant lymphoproliferative disorder (PTLD) is higher in kidney transplant recipients receiving monoclonal antibody induction therapy, but the aRR between the different available polyclonal agents has not been investigated in detail. We analyzed data from the...

journal_title：Pediatric transplantation

authors： Dharnidharka VR,Stevens G

更新日期：2005-10-01 00:00:00

abstract：:This review focuses on active clinical research in pediatric liver transplantation with special emphasis on areas that could benefit from studies utilizing the SPLIT infrastructure and data repository. Ideas were solicited by members of the SPLIT Research Committee and sections were drafted by members of the committee...

journal_title：Pediatric transplantation

authors： Alonso EM,Ng VL,Anand R,Anderson CD,Ekong UD,Fredericks EM,Furuya KN,Gupta NA,Lerret SM,Sundaram S,Tiao G,Studies of Pediatric Liver Transplantation (SPLIT) Research Group.

更新日期：2013-08-01 00:00:00

abstract：:DIDS is a unique form of combined immune deficiency characterized by an unusual susceptibility to cutaneous viral infections, severe allergies with eosinophilia and elevated immunoglobulin E titers, autoimmunity, and cancer. HSCT is considered the standard of care for this deadly disease. We have retrospectively analy...

journal_title：Pediatric transplantation

authors： Uygun DFK,Uygun V,Reisli İ,Keleş S,Özen A,Yılmaz M,Sayar EH,Daloğlu H,Öztürkmen SI,Çakı S,Karasu GT,Yeşilipek A

更新日期：2017-11-01 00:00:00

abstract：:Dysregulation of genes involved in the cell cycle such as TP53, P21, P16, and PTEN plays a key role in oncogenesis. We have earlier reported increased expression of the TP53 encoded protein p53, in bone marrow samples from pediatric patients with more aggressive, rare chronic myeloid malignancies. The aim of this stud...

journal_title：Pediatric transplantation

authors： Mattsson K,Honkaniemi E,Barbany G,Gustafsson B

更新日期：2015-11-01 00:00:00

abstract：:Methylmalonic acidemia with complete mutase deficiency (mut(0) type) is an inborn error of metabolism with high mortality and morbidity. LT has been suggested to be a solution to this disease, but elevation of urinary and blood MMA was still observed after LT. In this study, we measured dry blood spot MMA and its prec...

journal_title：Pediatric transplantation

authors： Chen PW,Hwu WL,Ho MC,Lee NC,Chien YH,Ni YH,Lee PH

更新日期：2010-05-01 00:00:00

abstract：:For infants with SCID, the ideal conditioning regimen before allogeneic HCT would omit cytotoxic chemotherapy to minimize short- and long-term complications. We performed a prospective pilot trial with G-CSF plus plerixafor given to the host to mobilize HSC from their niches. We enrolled six patients who received CD34...

journal_title：Pediatric transplantation

authors： Dvorak CC,Horn BN,Puck JM,Czechowicz A,Shizuru JA,Ko RM,Cowan MJ

更新日期：2014-09-01 00:00:00

abstract：:Children may have kidneys transplanted from donors larger than themselves. Abdominal wall closure may be difficult, with risks of abdominal compartment syndrome and graft compromise. Meshes used to facilitate closure may cause dense intra-abdominal adhesions, making further surgery or peritoneal dialysis difficult. We...

journal_title：Pediatric transplantation

authors： Pentlow A,Smart NJ,Richards SK,Inward CD,Morgan JD

更新日期：2008-02-01 00:00:00

abstract：:EPVO is a common cause of prehepatic portal hypertension in pediatric patients and sometimes results in cavernous transformation of the PV. We herein present the cases of two patients who underwent LDLT for EPVO with post-Kasai biliary atresia. PV reconstruction was performed with a porto-left gastric vein anastomosis...

journal_title：Pediatric transplantation

authors： Kitajima T,Sakamoto S,Uchida H,Hamano I,Kobayashi M,Kanazawa H,Fukuda A,Kasahara M

更新日期：2013-05-01 00:00:00

abstract：:Several studies suggested that the incidence of new-onset diabetes following pediatric kidney transplantation has increased markedly in recent years, with reported incidence of up to 20%. However, limited information is available regarding the incidence and features of pretransplant status of abnormal glucose toleranc...

journal_title：Pediatric transplantation

authors： Shishido S,Sato H,Asanuma H,Shindo M,Hataya H,Ishikura K,Hamasaki Y,Goto M,Ikeda M,Honda M

更新日期：2006-02-01 00:00:00

abstract：:AML with the RAM immunophenotype is associated with extremely poor prognosis. We report a rare case of monozygotic twins presenting simultaneously at the age of 2 years with RAM AML. Each twin underwent a myeloablative 7/10 unrelated umbilical cord blood transplant. Pretransplant Twin A's bone marrow was negative for ...

journal_title：Pediatric transplantation

authors： Abu-Arja RF,Dargart JL,Bajwa RPS,Kahwash SB,Auletta JJ,Rangarajan HG

更新日期：2018-12-01 00:00:00

abstract：:Facial transplantation has become a reality in adult medicine. Children are subject to congenital craniofacial differences, disease-related, traumatic, or thermochemical craniofacial changes and might be suitable for face transplantation. This manuscript addresses unique ethical issues in considering potential pediatr...

journal_title：Pediatric transplantation

authors： Benghiac AG,Garrett JR,Carter BS

更新日期：2017-11-01 00:00:00

abstract：:Vascular complications remain the most common cause of early renal allograft loss in patients with end-stage renal failure. Underlying thrombophilic disorders increase the risk of early graft thrombosis. A male adolescent with high-risk thrombophilia because of combined heterozygous factor V Leiden (G1691A) and prothr...

journal_title：Pediatric transplantation

authors： John U,Kentouche K,Nowak G,Schubert J,Misselwitz J

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:In adults, the time of day for LT does not affect post-transplant outcomes. Whether this is true or not in children is unknown. In this study, we aimed to evaluate if weekend and weeknight liver transplants are associated with worse patient and graft survival in children. METHODS:We interrogated the UNOS da...

journal_title：Pediatric transplantation

authors： Rogers ME,Egberg MD,Sylvester F,Lichtman S,Lin FC

更新日期：2020-12-01 00:00:00

abstract：:Pneumatosis intestinalis is an uncommon finding beyond the neonatal period, but it has been reported in immunocompromized pediatric patients. The association of pneumatosis intestinalis in children following renal transplantation has to the best of our knowledge been only reported once in children. We describe a 4-yea...

journal_title：Pediatric transplantation

authors： Chelimsky G,Blanchard S,Sivit C,Davis I,Czinn S

更新日期：2003-06-01 00:00:00

abstract：:Portal vein aneurysms are very rare and represent <3% of all venous aneurysms. They can be congenital or acquired. Most patients do not have liver disease at diagnosis. Although uncommon, portal vein aneurysm has been described after liver transplant. We report the case of a six-yr-old girl who presented with an aneur...

journal_title：Pediatric transplantation

authors： Molinares B,Alvarez S,García V,Sepúlveda ME,Yepes NL,Peláez S

更新日期：2013-02-01 00:00:00

abstract：:Bartter's syndrome (BS) is an incurable genetic disease, with variable response to supportive therapy relating to fluid and electrolyte management. Poor control or therapy non-compliance may result in frequent life threatening episodes of dehydration, acidosis and hypokalemia, with resultant adverse effects on patient...

journal_title：Pediatric transplantation

authors： Chaudhuri A,Salvatierra O Jr,Alexander SR,Sarwal MM

更新日期：2006-03-01 00:00:00

abstract：:Graft-vs-host disease (GVHD) is one of the most difficult problems in stem cell transplantation. It is best considered in the context of the normal immune response. The role of the immune system is to identify and eliminate foreign antigens. In the case of GVHD, the antigens are minor histocompatibility antigens (mHA)...

journal_title：Pediatric transplantation

authors： Antin JH

更新日期：2005-12-01 00:00:00

abstract：:This study reports the clinical complication and infection rates of an active pediatric IT program that has never utilized bowel decontamination in either the donor or the recipient. All patients undergoing IT from 2003 to 2015 at a single pediatric IT center were reviewed. Post-transplant surgical, infectious, and im...

journal_title：Pediatric transplantation

authors： Clouse JW,Kubal CA,Fridell JA,Mangus RS

更新日期：2018-05-01 00:00:00

abstract：:Sirolimus represents a major advancement in the field of solid organ transplantation and is being used as a rescue agent for acute and chronic rejection as well as for primary immunosuppression with good graft outcome. Although initial studies with sirolimus were in adults, now significant data have accumulated on the...

journal_title：Pediatric transplantation

authors： Gupta P,Kaufman S,Fishbein TM

更新日期：2005-06-01 00:00:00

abstract：:Recurrent and de novo disease is an increasing problem and is known to negatively impact transplant graft survival. Immunosuppressive medications have not had an impact on the prevalence of recurrent and de novo disease. Renal Allograft Disease Registry (RADR) was established to study the prevalence, impact and risk f...

journal_title：Pediatric transplantation

authors： Hariharan S,Savin VJ

更新日期：2004-08-01 00:00:00

abstract：:Bacillus cereus is a spore-forming, gram-positive bacterium that causes food poisoning presenting with either emesis or diarrhea. Diarrhea is caused by proteinaceous enterotoxin complexes, mainly hemolysin BL, non-hemolytic enterotoxin (NHE), and cytotoxin K. In contrast, emesis is caused by the ingestion of the depsi...

journal_title：Pediatric transplantation

authors： Tschiedel E,Rath PM,Steinmann J,Becker H,Dietrich R,Paul A,Felderhoff-Müser U,Dohna-Schwake C

更新日期：2015-02-01 00:00:00

abstract：:The aim of the study was to evaluate the cognitive and emotional development after pediatric liver transplantation. A total of 21 patients, aged 4-16.9 yr (median 9.6 yr) were tested 1-9 yr (median 4.2 yr) after the transplantation. The pretransplant diagnoses included biliary atresia (eight patients), various metabol...

journal_title：Pediatric transplantation

authors： Adebäck P,Nemeth A,Fischler B

更新日期：2003-10-01 00:00:00