The roles of RelA/(p)ppGpp in glucose-starvation induced adaptive response in the zoonotic Streptococcus suis.

abstract：:Utilization of computational approach in the study of social behaviour of animals is increasing and we attempted such an approach in our study of tree-dwelling bats. These bats live in highly dynamic fission-fusion societies that share multiple roosts in a common home range. The key behavioural component associated wi...

journal_title：Scientific reports

authors： Zelenka J,Kasanický T,Budinská I,Kaňuch P

更新日期：2020-10-08 00:00:00

abstract：:The current study aims at characterizing the mechanisms that allow humans to entrain the mind and body to incoming rhythmic sensory inputs in real time. We addressed this unresolved issue by examining the relationship between covert neural processes and overt behavior in the context of musical rhythm. We measured temp...

journal_title：Scientific reports

authors： Nozaradan S,Peretz I,Keller PE

更新日期：2016-02-05 00:00:00

abstract：:Specialized processing in the brain is performed by multiple groups of brain regions organized as functional modules. Although, in vivo studies of brain functional modules involve multiple functional Magnetic Resonance Imaging (fMRI) scans, the methods used to derive functional modules from functional networks of the ...

journal_title：Scientific reports

authors： Gupta S,Rajapakse JC

更新日期：2020-05-05 00:00:00

abstract：:Pesticides are the main tactics for pest control because they reduce the pest population very fast and their efficiency does not depend on abiotic factors. However, the indiscriminate use of these substances can speed up the development of resistant populations and causing environmental contamination. Therefore, alter...

journal_title：Scientific reports

authors： Campos EVR,Proença PLF,Oliveira JL,Pereira AES,de Morais Ribeiro LN,Fernandes FO,Gonçalves KC,Polanczyk RA,Pasquoto-Stigliani T,Lima R,Melville CC,Della Vechia JF,Andrade DJ,Fraceto LF

更新日期：2018-05-16 00:00:00

abstract：:Genes with similar roles in the cell cluster on chromosomes, thus benefiting from coordinated regulation. This allows gene function to be inferred by transferring annotations from genomic neighbors, following the guilt-by-association principle. We performed a systematic search for co-occurrence of >1000 gene functions...

journal_title：Scientific reports

authors： Mihelčić M,Šmuc T,Supek F

更新日期：2019-12-20 00:00:00

abstract：:Electroceutical wound dressings, especially those involving current flow with silver based electrodes, show promise for treating biofilm infections. However, their mechanism of action is poorly understood. We have developed an in vitro agar based model using a bioluminescent strain of Pseudomonas aeruginosa to measure...

journal_title：Scientific reports

authors： Dusane DH,Lochab V,Jones T,Peters CW,Sindeldecker D,Das A,Roy S,Sen CK,Subramaniam VV,Wozniak DJ,Prakash S,Stoodley P

更新日期：2019-02-14 00:00:00

abstract：:Changes in immune and coagulation systems and possible viral spread through the blood-brain barrier have been described in SARS-CoV-2 infection. In this study, we evaluated the possible retinal involvement and ocular findings in severe COVID-19 pneumonia patients. A cross-sectional study was conducted on 46 patients a...

journal_title：Scientific reports

authors： Pirraglia MP,Ceccarelli G,Cerini A,Visioli G,d'Ettorre G,Mastroianni CM,Pugliese F,Lambiase A,Gharbiya M

更新日期：2020-10-15 00:00:00

abstract：:Electron ptychography has seen a recent surge of interest for phase sensitive imaging at atomic or near-atomic resolution. However, applications are so far mainly limited to radiation-hard samples, because the required doses are too high for imaging biological samples at high resolution. We propose the use of non-conv...

journal_title：Scientific reports

authors： Pelz PM,Qiu WX,Bücker R,Kassier G,Miller RJD

更新日期：2017-08-29 00:00:00

abstract：:Tumor genetic heterogeneity may underlie poor clinical outcomes because diverse subclones could be comprised of metastatic and drug resistant cells. Targeted deep sequencing has been used widely as a diagnostic tool to identify actionable mutations in cancer patients. In this study, we evaluated the clinical utility o...

journal_title：Scientific reports

authors： Oh BY,Shin HT,Yun JW,Kim KT,Kim J,Bae JS,Cho YB,Lee WY,Yun SH,Park YA,Park YH,Im YH,Lee J,Joung JG,Kim HC,Park WY

更新日期：2019-03-14 00:00:00

abstract：:Adult tissue-derived mesenchymal stromal cells (MSCs) are showing promise in clinical trials for systemic lupus erythematosus (SLE). However, the inability to manufacture large quantities of functional cells from a single donor as well as donor-dependent variability in quality limits their clinical utility. Human embr...

journal_title：Scientific reports

authors： Thiel A,Yavanian G,Nastke MD,Morales P,Kouris NA,Kimbrel EA,Lanza R

更新日期：2015-12-02 00:00:00

abstract：:Fibrous scaffolds are used for bone tissue engineering purposes with great success across a variety of polymers with different physical and chemical properties. It is now evident that the correct degree of curvature promotes increased cytoskeletal tension on osteoprogenitors leading to osteogenic differentiation. Howe...

journal_title：Scientific reports

authors： Ozdemir T,Bowers DT,Zhan X,Ghosh D,Brown JL

更新日期：2019-01-30 00:00:00

abstract：:The high failure strain of thermoplastic elastomers (TPEs) is a very desirable feature for rechargeable Li-ion batteries by improving the lifetime of high specific capacity anode materials that undergo mechanical fractures induced by large volume variations. In this work, poly(styrene-b-2-hydroxyethyl acrylate) called...

journal_title：Scientific reports

authors： Tesfaye AT,Dumur F,Gigmes D,Maria S,Monconduit L,Djenizian T

更新日期：2019-03-13 00:00:00

abstract：:We propose a reflection type metal-insulator-metal (MIM) metasurface composed of hybrid nano-antennas for comprehensive spatial engineering of the properties of optical fields. The capability of such structure is illustrated in the design of a device that can be used to produce a radially polarized vectorial beam for ...

journal_title：Scientific reports

authors： Wang S,Zhan Q

更新日期：2016-07-15 00:00:00

abstract：:Muscle differentiation is a complex process in which muscle progenitor cells undergo determination and eventually cellular fusion. This process is heavily regulated by such master transcription factors as MYOD and members of the MEF2 family. Here, we show that the transcription factor ZNF148 plays a direct role in hum...

journal_title：Scientific reports

authors： Bakke J,Wright WC,Zamora AE,Ong SS,Wang YM,Hoyer JD,Brewer CT,Thomas PG,Chen T

更新日期：2017-08-15 00:00:00

abstract：:Previous trial evidence suggested potential risk of serious urinary tract infections (UTIs) and genital infections in type 2 diabetes patients using sodium glucose co-transporter-2 inhibitors (SGLT2) inhibitors. We conducted a systematic review and meta-analysis to assess the effects of SGLT2 inhibitors on UTIs and ge...

journal_title：Scientific reports

authors： Liu J,Li L,Li S,Jia P,Deng K,Chen W,Sun X

更新日期：2017-06-06 00:00:00

abstract：ABSTARCT:The relationship between chronic kidney disease (CKD), which is defined by declined estimated glomerular filtration rate (eGFR) and/or proteinuria, and asymptomatic intracranial arterial stenosis (ICAS) is largely unknown. We conducted a population-based, cross-sectional study by recruiting 5209 participants f...

journal_title：Scientific reports

authors： Li Z,Li J,Wang A,Pan H,Wu S,Zhao X

更新日期：2017-07-04 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is one of the most common inflammatory diseases resulting from habitual smoking. Impaired clearance of apoptotic cell by airway macrophages contributes to lung inflammation. Milk fat globule-EGF factor 8 (MFG-E8), as a link between apoptotic cells and phagocytes, facilitate...

journal_title：Scientific reports

authors： Wang Y,Luo G,Chen J,Jiang R,Zhu J,Hu N,Huang W,Cheng G,Jia M,Su B,Zhang N,Cui T

更新日期：2017-02-14 00:00:00

abstract：:Enterococcus faecalis, an organism generally not pathogenic for healthy humans, has the potential to cause disease in susceptible hosts. While it seems to be equipped to interact with and circumvent host immune defense, most of the molecular and cellular mechanisms underlying the enterococcal infectious process remain...

journal_title：Scientific reports

authors： Nunez N,Derré-Bobillot A,Gaubert S,Herry JM,Deschamps J,Wei Y,Baranek T,Si-Tahar M,Briandet R,Serror P,Archambaud C

更新日期：2018-01-29 00:00:00

abstract：:Tupistra chinensis is widely distributed in southwestern China and its rhizome is a famous folk medicine for the treatment of carbuncles and pharyngitis. Its chemical identity of potent antiproliferative and anti-inflammatory constituents has been carried out in this study. Twenty-three polyhydroxylated spirostanol sa...

journal_title：Scientific reports

authors： Xiang L,Yi X,Wang Y,He X

更新日期：2016-08-17 00:00:00

abstract：:Different marine habitats are characterised by different soundscapes. How or which differences may be representative of the habitat characteristics and/or community structure remains however to be explored. A growing project in passive acoustics is to find a way to use soundscapes to have information on the habitat an...

journal_title：Scientific reports

authors： Bertucci F,Parmentier E,Lecellier G,Hawkins AD,Lecchini D

更新日期：2016-09-15 00:00:00

abstract：:The precision and accuracy of quantifying semi-volatile organic compounds (SVOCs) in solution by GC/MS, particularly when volume errors are unpredictable or difficult to control, are improved by utilizing internal standards (IS). Not obvious though is the extent to which timing IS addition affects measurement. To illu...

journal_title：Scientific reports

authors： Otim O,Rocha J Jr

更新日期：2020-10-19 00:00:00

abstract：:Worldwide, prostate cancer (PCa) is the second most common malignancy in males. We undertook a meta-analysis to compare the efficacy and safety of conventional laparoscopic radical prostatectomy with a transperitoneal (TLRP) approach, versus that of an extraperitoneal (ELRP) approach, for treatment of localized PCa. A...

journal_title：Scientific reports

authors： De Hong C,Liang Ren L,Qiang W,Jia W,Ying Chun H,Lu Y,Zheng Hua L,Heng Ping L,Shi Bing Y,Yun Xiang L

更新日期：2015-10-13 00:00:00

abstract：:Many studies have now consistently reported that the phase angle of ongoing oscillatory activity (measured using EEG/MEG), at time of stimulus presentation influences detection when stimuli are near-threshold. However, studies examining whether the adjustment of the phase angle of oscillations is under top-down attent...

journal_title：Scientific reports

authors： van Diepen RM,Mazaheri A

更新日期：2018-02-14 00:00:00

abstract：:The microRNA (miR)-183/96/182 cluster plays important roles in the development and functions of sensory organs, including the inner ear. Point-mutations in the seed sequence of miR-96 result in non-syndromic hearing loss in both mice and humans. However, the lack of a functionally null mutant has hampered the evaluati...

journal_title：Scientific reports

authors： Geng R,Furness DN,Muraleedharan CK,Zhang J,Dabdoub A,Lin V,Xu S

更新日期：2018-12-21 00:00:00

abstract：:Awe, a complex emotion composed by the appraisal components of vastness and need for accommodation, is a profound and often meaningful experience. Despite its importance, psychologists have only recently begun empirical study of awe. At the experimental level, a main issue concerns how to elicit high intensity awe exp...

journal_title：Scientific reports

authors： Chirico A,Cipresso P,Yaden DB,Biassoni F,Riva G,Gaggioli A

更新日期：2017-04-27 00:00:00

abstract：:Dogs (Canis familiaris) are the first animals to be domesticated by humans and the only ones domesticated by mobile hunter-gatherers. Wolves and humans were both persistent, pack hunters of large prey. They were species competing over resources in partially overlapping ecological niches and capable of killing each oth...

journal_title：Scientific reports

authors： Lahtinen M,Clinnick D,Mannermaa K,Salonen JS,Viranta S

更新日期：2021-01-07 00:00:00

abstract：:The amygdala plays a critical role in emotion. Its functional coupling with the hippocampus and ventromedial prefrontal cortex extending to a portion of the anterior cingulate cortex (ACC) is implicated in anxiogenesis and hypothalamic-pituitary-adrenal (HPA) system regulation. However, it remains unclear how amygdala...

journal_title：Scientific reports

authors： Hakamata Y,Komi S,Moriguchi Y,Izawa S,Motomura Y,Sato E,Mizukami S,Kim Y,Hanakawa T,Inoue Y,Tagaya H

更新日期：2017-08-16 00:00:00

abstract：:Rapid diagnostic tests (RDTs) have been widely deployed in low-resource settings. These tests are typically read by visual inspection, and accurate record keeping and data aggregation remains a substantial challenge. A successful malaria elimination campaign will require new strategies that maximize the sensitivity of...

journal_title：Scientific reports

authors： Scherr TF,Gupta S,Wright DW,Haselton FR

更新日期：2016-06-27 00:00:00

abstract：:Peatlands perform important ecosystem functions, such as carbon storage and nutrient retention, which are affected, among other factors, by vegetation and peat decomposition. The availability of silicon (Si) in peatlands differs strongly, ranging from <1 to >25 mg L-1. Since decomposition of organic material was recen...

journal_title：Scientific reports

authors： Reithmaier GS,Knorr KH,Arnhold S,Planer-Friedrich B,Schaller J

更新日期：2017-08-18 00:00:00

abstract：:There is significant interest in understanding the pathophysiology of Obsessive-Compulsive Disorder (OCD) using resting-state fMRI (rsfMRI). Previous studies acknowledge abnormalities within and beyond the fronto-striato-limbic circuit in OCD that require further clarifications. However, limited information could be i...

journal_title：Scientific reports

authors： Kashyap R,Eng GK,Bhattacharjee S,Gupta B,Ho R,Ho CSH,Zhang M,Mahendran R,Sim K,Chen SHA

更新日期：2021-01-14 00:00:00