A Chelation Strategy for In-situ Constructing Surface Oxygen Vacancy on {001} Facets Exposed BiOBr Nanosheets.

abstract：:Due to limited availability of pharmacological therapies, triple-negative breast cancer (TNBC) is the subtype with worst outcome. We hypothesised that 2-Deoxy-D-Glucose (2-DG), a glucose analogue, may hold potential as a therapy for particularly aggressive TNBC. We investigated 2-DG's effects on TNBC cell line variant...

journal_title：Scientific reports

authors： O'Neill S,Porter RK,McNamee N,Martinez VG,O'Driscoll L

更新日期：2019-03-07 00:00:00

abstract：:In the event of a nuclear attack or large-scale radiation event, there would be an urgent need for assessing the dose to which hundreds or thousands of individuals were exposed. Biodosimetry approaches are being developed to address this need, including transcriptomics. Studies have identified many genes with potentia...

journal_title：Scientific reports

authors： Ghandhi SA,Shuryak I,Morton SR,Amundson SA,Brenner DJ

更新日期：2019-12-05 00:00:00

abstract：:Embryo implantation requires a hospitable uterine environment. A key metabolic change that occurs during the peri-implantation period, and throughout early pregnancy, is the rise in endometrial glycogen content. Glycogen accumulation requires prior cellular uptake of glucose. Here we show that both human and murine en...

journal_title：Scientific reports

authors： Salker MS,Singh Y,Zeng N,Chen H,Zhang S,Umbach AT,Fakhri H,Kohlhofer U,Quintanilla-Martinez L,Durairaj RRP,Barros FSV,Vrljicak P,Ott S,Brucker SY,Wallwiener D,Vrhovac Madunić I,Breljak D,Sabolić I,Koepsell H,Brosens

更新日期：2017-10-03 00:00:00

abstract：:Several systems can be represented as multiplex networks, i.e. in terms of a superposition of various graphs, each related to a different mode of connection between nodes. Hence, the definition of proper mathematical quantities aiming at capturing the added level of complexity of those systems is required. Various ste...

journal_title：Scientific reports

authors： Gemmetto V,Garlaschelli D

更新日期：2015-03-13 00:00:00

abstract：:Liver segmentation is an essential procedure in computer-assisted surgery, radiotherapy, and volume measurement. It is still a challenging task to extract liver tissue from 3D CT images owing to nearby organs with similar intensities. In this paper, an automatic approach integrating multi-dimensional features into gra...

journal_title：Scientific reports

authors： Lu X,Xie Q,Zha Y,Wang D

更新日期：2018-07-16 00:00:00

abstract：:Membrane protein oligomerization mediates a wide range of biological events including signal transduction, viral infection and membrane curvature induction. However, the relative contributions of protein-protein and protein-membrane interactions to protein oligomerization remain poorly understood. Here, we used the Ca...

journal_title：Scientific reports

authors： Tao M,Isas JM,Langen R

更新日期：2020-03-24 00:00:00

abstract：:Tissue-resident memory T (TRM) cells are characterized by their surface expression of CD69 and can be subdivided in CD103+ and CD103- TRM cells. The origin and functional characteristics of TRM cells in the renal allograft are largely unknown. To determine these features we studied TRM cells in transplant nephrectomie...

journal_title：Scientific reports

authors： de Leur K,Dieterich M,Hesselink DA,Corneth OBJ,Dor FJMF,de Graav GN,Peeters AMA,Mulder A,Kimenai HJAN,Claas FHJ,Clahsen-van Groningen MC,van der Laan LJW,Hendriks RW,Baan CC

更新日期：2019-04-12 00:00:00

abstract：:Patients who undergo orthotopic liver transplantation often sustain acute kidney injury(AKI). The toll-like receptor 4(TLR4)/Nuclear factor-кB(NF-кB) pathway plays a role in AKI. Dexmedetomidine(Dex) has been shown to attenuate AKI. The current study aimed to determine whether liver transplantation-induced AKI is asso...

journal_title：Scientific reports

authors： Yao H,Chi X,Jin Y,Wang Y,Huang P,Wu S,Xia Z,Cai J

更新日期：2015-11-20 00:00:00

abstract：:Mayaro virus (MAYV) is endemic in South American countries where it is responsible for sporadic outbreaks of acute febrile illness. The hallmark of MAYV infection is a highly debilitating and chronic arthralgia. Although MAYV emergence is a potential threat, there are no specific therapies or licensed vaccine. In this...

journal_title：Scientific reports

authors： Mota MTO,Costa VV,Sugimoto MA,Guimarães GF,Queiroz-Junior CM,Moreira TP,de Sousa CD,Santos FM,Queiroz VF,Passos I,Hubner J,Souza DG,Weaver SC,Teixeira MM,Nogueira ML

更新日期：2020-03-24 00:00:00

abstract：:Evidence showed preventive impacts of the highly active antiretroviral therapy (HAART) on the Human Immunodeficiency Virus (HIV) transmission amomg heterosexual population, however, that is of deficit among men who have sex with men (MSM). The aim was to systematically examine the efficacy of HAART on HIV transmission...

journal_title：Scientific reports

authors： Jiang Y,Su S,Borné Y

更新日期：2020-01-23 00:00:00

abstract：:We discovered a technical solution of such outstanding importance that it can trigger new approaches in silicon wet etching processing and, in particular, photovoltaic cell manufacturing. The so called inverted pyramid arrays, outperforming conventional pyramid textures and black silicon because of their superior ligh...

journal_title：Scientific reports

authors： Wang Y,Yang L,Liu Y,Mei Z,Chen W,Li J,Liang H,Kuznetsov A,Xiaolong D

更新日期：2015-06-02 00:00:00

abstract：:When searching a target in a natural scene, it has been shown that both the target's visual properties and similarity to the background influence whether and how fast humans are able to find it. So far, it was unclear whether searchers adjust the dynamics of their eye movements (e.g., fixation durations, saccade ampli...

journal_title：Scientific reports

authors： Rothkegel LOM,Schütt HH,Trukenbrod HA,Wichmann FA,Engbert R

更新日期：2019-02-07 00:00:00

abstract：:Some ant species have multiple worker castes that differ in body size; workers in one caste remain in the colony and those in the other forage outside the colony (caste polyethism). In other species, all workers engage in both tasks, but the younger workers remain in the colony and the older workers forage (age polyet...

journal_title：Scientific reports

authors： Iwasa Y,Yamaguchi S

更新日期：2020-02-24 00:00:00

abstract：:A novel strategy for amplification full-length cDNA and promoter sequences has been developed using bioinformatics technology and multiplexed PCR methods in this study. The amplification of 3' ends of cDNA is performed according to the modified classic 3' RACE techniques, therein the more efficient and effective oligo...

journal_title：Scientific reports

authors： Chen N,Wang WM,Wang HL

更新日期：2016-01-13 00:00:00

abstract：:The classical view of nerve growth factor (NGF) action in the nervous system is linked to its retrograde axonal transport. However, almost nothing is known on the trafficking properties of its unprocessed precursor proNGF, characterized by different and generally opposite biological functions with respect to its matur...

journal_title：Scientific reports

authors： De Nadai T,Marchetti L,Di Rienzo C,Calvello M,Signore G,Di Matteo P,Gobbo F,Turturro S,Meucci S,Viegi A,Beltram F,Luin S,Cattaneo A

更新日期：2016-02-01 00:00:00

abstract：:We report the transient memory device by means of a water soluble SSG (solid sodium with glycerine) paper. This material has a hydroscopic property hence it can be soluble in water. In terms of physical security of memory devices, prompt abrogation of a memory device which stored a large number of data is crucial when...

journal_title：Scientific reports

authors： Bae H,Lee BH,Lee D,Seol ML,Kim D,Han JW,Kim CK,Jeon SB,Ahn D,Park SJ,Park JY,Choi YK

更新日期：2016-12-05 00:00:00

abstract：:Although giant proximity effect (GPE) can shed important information on understanding superconducting pairing mechanisms and superconducting electronics, reports on the GPE are few because the fabrication of the junctions with GPE is technologically difficult. Here, we report a GPE in the single-crystalline MgB2 bilay...

journal_title：Scientific reports

authors： Jung SG,Pham D,Park TH,Choi HY,Seo JW,Kang WN,Park T

更新日期：2019-03-01 00:00:00

abstract：:2-Bromo-5-(2-bromo-2-nitrovinyl)furan (G1 or Furvina) is an antimicrobial with a direct reactivity against thiol groups. It is active against Gram-positive and Gram-negative bacteria, yeasts and filamentous fungi. By reacting with thiol groups it causes direct damage to proteins but, as a result, is very short-living ...

journal_title：Scientific reports

authors： Allas UL,Toom L,Selyutina A,Mäeorg U,Medina R,Merits A,Rinken A,Hauryliuk V,Kaldalu N,Tenson T

更新日期：2016-11-10 00:00:00

abstract：:Preclinical studies show that the dopamine D3 receptor (D3R) is involved in the reinstatement of drug seeking and motivation for drugs of abuse. A D3R gene variant, Ser9Gly (rs6280) has been linked to nicotine dependence, yet the mechanisms underlying its involvement in nicotine dependence is unclear. This study inves...

journal_title：Scientific reports

authors： Chukwueke CC,Kowalczyk WJ,Di Ciano P,Gendy M,Taylor R,Heishman SJ,Le Foll B

更新日期：2020-03-05 00:00:00

abstract：:To explore a simple and easy-to-learn procedure for the isolation of human quiescent hepatic stellate cells (HSCs) that requires no advanced training. Thus reducing costs and increasing efficiency. This protocol will provide sufficient primary cells with minimal contaminants for future basic research on diseases assoc...

journal_title：Scientific reports

authors： Zhai X,Wang W,Dou D,Ma Y,Gang D,Jiang Z,Shi B,Jin B

更新日期：2019-09-04 00:00:00

abstract：:The aim of this study was to identify mRNA targets of dysregulated miRNAs through the integrated analysis of miRNA and mRNA expression profiling in men with normal versus impaired spermatogenesis. The expression of mRNAs and miRNAs in testicular tissues obtained from males with non-obstructive azoospermia (NOA, n = 4)...

journal_title：Scientific reports

authors： Zhuang X,Li Z,Lin H,Gu L,Lin Q,Lu Z,Tzeng CM

更新日期：2015-01-28 00:00:00

abstract：:Adherence to norms and interventions to norm violations are two important forms of social behaviour modelled in economic games. While both appear to serve a prosocial function, they may represent separate mechanisms corresponding with distinct emotional and psychological antecedents, and thus may be predicted by diffe...

journal_title：Scientific reports

authors： Zhao K,Ferguson E,Smillie LD

更新日期：2017-06-13 00:00:00

abstract：:The optimized strategy to further increase the success rate of ablation for ventricular arrhythmias (VAs) from the right ventricular outflow tract (RVOT) is challenging. Recent studies have shown that the pulmonary sinus cusp (PSC) region may be the origin of certain RVOT VAs. We evaluated the efficacy of preferential...

journal_title：Scientific reports

authors： Xie Y,Liu A,Jin Q,Zhang N,Jia K,Lin C,Ling T,Chen K,Pan W,Wu L

更新日期：2020-10-20 00:00:00

abstract：:Even after years of experiencing malaria, caused by infection with Plasmodium species, individuals still have incomplete immunity and develop low-density parasitemia on re-infection. Previous studies using the P. chabaudi (Pch) mouse model to understand the reason for chronic malaria, found that mice with a deletion o...

journal_title：Scientific reports

authors： Horne-Debets JM,Karunarathne DS,Faleiro RJ,Poh CM,Renia L,Wykes MN

更新日期：2016-05-24 00:00:00

abstract：:Cardiac contractility is enhanced by phosphorylation of myosin light chain 2 (MLC2) by cardiac-specific MLC kinase (cMLCK), located at the neck region of myosin heavy chain. In normal mouse and human hearts, the level of phosphorylation is maintained relatively constant, at around 30-40% of total MLC2, likely by well-...

journal_title：Scientific reports

authors： X Cai L,Tanada Y,D Bello G,C Fleming J,F Alkassis F,Ladd T,Golde T,Koh J,Chen S,Kasahara H

更新日期：2019-08-29 00:00:00

abstract：:Supported by histological and genetic evidence implicating myelin, neuroinflammation and oligodendrocyte dysfunction in schizophrenia spectrum disorders (SZ), diffusion tensor imaging (DTI) studies have consistently shown white matter (WM) abnormalities when compared to healthy controls (HC). The diagnostic specificit...

journal_title：Scientific reports

authors： Tønnesen S,Kaufmann T,Doan NT,Alnæs D,Córdova-Palomera A,Meer DV,Rokicki J,Moberget T,Gurholt TP,Haukvik UK,Ueland T,Lagerberg TV,Agartz I,Andreassen OA,Westlye LT

更新日期：2018-09-20 00:00:00

abstract：:Inorganic semiconductors such as III-V materials are very important in our everyday life as they are used for manufacturing optoelectronic and microelectronic components with important applications span from energy harvesting to telecommunications. In some applications, these components are required to operate in hars...

journal_title：Scientific reports

authors： Ng WH,Lu Y,Liu H,Carmalt CJ,Parkin IP,Kenyon AJ

更新日期：2018-02-23 00:00:00

abstract：:The pathological mechanism of Kashin-Beck disease (KBD), an endemic osteoarthritic disease, remains to be poorly understood. This study was designed to identify signaling pathways and crucial proteins involved in the pathological mechanism of KBD compared with osteoarthritis (OA). The knee cartilage samples were colle...

journal_title：Scientific reports

authors： Lei J,Amhare AF,Wang L,Lv Y,Deng H,Gao H,Guo X,Han J,Lammi MJ

更新日期：2020-04-22 00:00:00

abstract：:Baeyer-Villiger monooxygenases (BVMOs) are able to catalyze regiospecific Baeyer-Villiger oxygenation of a variety of cyclic and linear ketones to generate the corresponding lactones and esters, respectively. However, the enzymes are usually difficult to express in a functional form in microbial cells and are rather u...

journal_title：Scientific reports

authors： Seo JH,Kim HH,Jeon EY,Song YH,Shin CS,Park JB

更新日期：2016-06-17 00:00:00

abstract：:α-synuclein (aS) is a natively unfolded pre-synaptic protein found in all Parkinson's disease patients as the major component of fibrillar plaques. Metal ions, and especially Cu(II), have been demonstrated to accelerate aggregation of aS into fibrillar plaques, the precursors to Lewy bodies. In this work, copper bindi...

journal_title：Scientific reports

authors： Rose F,Hodak M,Bernholc J

更新日期：2011-01-01 00:00:00