Guided post-acceleration of laser-driven ions by a miniature modular structure.

abstract：:For societies with writing systems, hereditary leadership is documented as one of the hallmarks of early political complexity and governance. In contrast, it is unknown whether hereditary succession played a role in the early formation of prehistoric complex societies that lacked writing. Here we use an archaeogenomic...

journal_title：Nature communications

authors： Kennett DJ,Plog S,George RJ,Culleton BJ,Watson AS,Skoglund P,Rohland N,Mallick S,Stewardson K,Kistler L,LeBlanc SA,Whiteley PM,Reich D,Perry GH

更新日期：2017-02-21 00:00:00

abstract：:Detection of Identical-By-Descent (IBD) segments provides a fundamental measure of genetic relatedness and plays a key role in a wide range of analyses. We develop FastSMC, an IBD detection algorithm that combines a fast heuristic search with accurate coalescent-based likelihood calculations. FastSMC enables biobank-s...

journal_title：Nature communications

authors： Nait Saada J,Kalantzis G,Shyr D,Cooper F,Robinson M,Gusev A,Palamara PF

更新日期：2020-11-30 00:00:00

abstract：:The efficient selection and isolation of individual cells of interest from a mixed population is desired in many biomedical and clinical applications. Here we show the concept of using photoswitchable semiconducting polymer dots (Pdots) as an optical 'painting' tool, which enables the selection of certain adherent cel...

journal_title：Nature communications

authors： Kuo CT,Thompson AM,Gallina ME,Ye F,Johnson ES,Sun W,Zhao M,Yu J,Wu IC,Fujimoto B,DuFort CC,Carlson MA,Hingorani SR,Paguirigan AL,Radich JP,Chiu DT

更新日期：2016-04-27 00:00:00

abstract：:Heart failure (HF) is a leading cause of mortality. Inflammation is implicated in HF, yet clinical trials targeting pro-inflammatory cytokines in HF were unsuccessful, possibly due to redundant functions of individual cytokines. Searching for better cardiac inflammation targets, here we link T cells with HF developmen...

journal_title：Nature communications

authors： Kallikourdis M,Martini E,Carullo P,Sardi C,Roselli G,Greco CM,Vignali D,Riva F,Ormbostad Berre AM,Stølen TO,Fumero A,Faggian G,Di Pasquale E,Elia L,Rumio C,Catalucci D,Papait R,Condorelli G

更新日期：2017-03-06 00:00:00

abstract：:Light propagating in tissue attains a spectrum that varies with location due to wavelength-dependent fluence attenuation, an effect that causes spectral corruption. Spectral corruption has limited the quantification accuracy of optical and optoacoustic spectroscopic methods, and impeded the goal of imaging blood oxyge...

journal_title：Nature communications

authors： Tzoumas S,Nunes A,Olefir I,Stangl S,Symvoulidis P,Glasl S,Bayer C,Multhoff G,Ntziachristos V

更新日期：2016-06-30 00:00:00

abstract：:Vesicular photothermal therapy agents (PTAs) are highly desirable in photothermal therapy (PTT) for their excellent light-harvesting ability and versatile hollow compartments. However, up to now, the reported vesicular PTAs are generally self-assembled from small molecules like liposomes, and polymer vesicles have sel...

journal_title：Nature communications

authors： Liu Y,Wang H,Li S,Chen C,Xu L,Huang P,Liu F,Su Y,Qi M,Yu C,Zhou Y

更新日期：2020-04-07 00:00:00

abstract：:Density functional theory (DFT) is the standard formalism to study the electronic structure of matter at the atomic scale. In Kohn-Sham DFT simulations, the balance between accuracy and computational cost depends on the choice of exchange and correlation functional, which only exists in approximate form. Here, we prop...

journal_title：Nature communications

authors： Dick S,Fernandez-Serra M

更新日期：2020-07-14 00:00:00

abstract：:Natriuretic peptides (NPs) are important hormones that regulate multiple cellular functions including cardiovascular physiology. In the heart, two natriuretic peptide receptors NPR1 and NPR2 act as membrane guanylyl cyclases to produce 3',5'-cyclic guanosine monophosphate (cGMP). Although both receptors protect from c...

journal_title：Nature communications

authors： Subramanian H,Froese A,Jönsson P,Schmidt H,Gorelik J,Nikolaev VO

更新日期：2018-06-22 00:00:00

abstract：:Direct reciprocity is a mechanism for cooperation among humans. Many of our daily interactions are repeated. We interact repeatedly with our family, friends, colleagues, members of the local and even global community. In the theory of repeated games, it is a tacit assumption that the various games that a person plays ...

journal_title：Nature communications

authors： Reiter JG,Hilbe C,Rand DG,Chatterjee K,Nowak MA

更新日期：2018-02-07 00:00:00

abstract：:As an in-plane charge current flows in a heavy metal film with spin-orbit coupling, it produces a torque on and thereby switches the magnetization in a neighbouring ferromagnetic metal film. Such spin-orbit torque (SOT)-induced switching has been studied extensively in recent years and has shown higher efficiency than...

journal_title：Nature communications

authors： Li P,Liu T,Chang H,Kalitsov A,Zhang W,Csaba G,Li W,Richardson D,DeMann A,Rimal G,Dey H,Jiang JS,Porod W,Field SB,Tang J,Marconi MC,Hoffmann A,Mryasov O,Wu M

更新日期：2016-09-01 00:00:00

abstract：:Colorectal cancer (CRC) transcriptional subtypes have been recently identified by gene expression profiling. Here we describe an analytical pipeline, microRNA master regulator analysis (MMRA), developed to search for microRNAs potentially driving CRC subtypes. Starting from a microRNA-mRNA tumour expression data set, ...

journal_title：Nature communications

authors： Cantini L,Isella C,Petti C,Picco G,Chiola S,Ficarra E,Caselle M,Medico E

更新日期：2015-11-17 00:00:00

abstract：:The spatial organization of chromosomes has key functional roles, yet how chromosomes fold remains poorly understood at the single-molecule level. Here, we employ models of polymer physics to investigate DNA loci in human HCT116 and IMR90 wild-type and cohesin depleted cells. Model predictions on single-molecule struc...

journal_title：Nature communications

authors： Conte M,Fiorillo L,Bianco S,Chiariello AM,Esposito A,Nicodemi M

更新日期：2020-07-03 00:00:00

abstract：:Amongst the many spectacular properties of hybrid lead halide perovskites, their defect tolerance is regarded as the key enabler for a spectrum of high-performance optoelectronic devices that propel perovskites to prominence. However, the plateauing efficiency enhancement of perovskite devices calls into question the ...

journal_title：Nature communications

authors： Righetto M,Lim SS,Giovanni D,Lim JWM,Zhang Q,Ramesh S,Tay YKE,Sum TC

更新日期：2020-06-01 00:00:00

abstract：:It is well known that a topologically protected gapless state appears at an interface between a topological insulator and an ordinary insulator; however, the physics of the interface between a topological insulator and a metal has largely been left unexplored. Here we report a novel phenomenon termed topological proxi...

journal_title：Nature communications

authors： Shoman T,Takayama A,Sato T,Souma S,Takahashi T,Oguchi T,Segawa K,Ando Y

更新日期：2015-03-12 00:00:00

abstract：:Sphingomyelin phosphodiesterase acid-like 3b (SMPDL3b) is a lipid raft enzyme that regulates plasma membrane (PM) fluidity. Here we report that SMPDL3b excess, as observed in podocytes in diabetic kidney disease (DKD), impairs insulin receptor isoform B-dependent pro-survival insulin signaling by interfering with insu...

journal_title：Nature communications

authors： Mitrofanova A,Mallela SK,Ducasa GM,Yoo TH,Rosenfeld-Gur E,Zelnik ID,Molina J,Varona Santos J,Ge M,Sloan A,Kim JJ,Pedigo C,Bryn J,Volosenco I,Faul C,Zeidan YH,Garcia Hernandez C,Mendez AJ,Leibiger I,Burke GW,Futerm

更新日期：2019-06-19 00:00:00

abstract：:Defect-free monolayers of graphene and hexagonal boron nitride are surprisingly permeable to thermal protons, despite being completely impenetrable to all gases. It remains untested whether small ions can permeate through the two-dimensional crystals. Here we show that mechanically exfoliated graphene and hexagonal bo...

journal_title：Nature communications

authors： Mogg L,Zhang S,Hao GP,Gopinadhan K,Barry D,Liu BL,Cheng HM,Geim AK,Lozada-Hidalgo M

更新日期：2019-09-18 00:00:00

abstract：:β-Diguetoxin-Dc1a (Dc1a) is a toxin from the desert bush spider Diguetia canities that incapacitates insects at concentrations that are non-toxic to mammals. Dc1a promotes opening of German cockroach voltage-gated sodium (Nav) channels (BgNav1), whereas human Nav channels are insensitive. Here, by transplanting common...

journal_title：Nature communications

authors： Bende NS,Dziemborowicz S,Mobli M,Herzig V,Gilchrist J,Wagner J,Nicholson GM,King GF,Bosmans F

更新日期：2014-07-11 00:00:00

abstract：:The allotetraploid plant Nicotiana tabacum (common tobacco) is a major crop species and a model organism, for which only very fragmented genomic sequences are currently available. Here we report high-quality draft genomes for three main tobacco varieties. These genomes show both the low divergence of tobacco from its ...

journal_title：Nature communications

authors： Sierro N,Battey JN,Ouadi S,Bakaher N,Bovet L,Willig A,Goepfert S,Peitsch MC,Ivanov NV

更新日期：2014-05-08 00:00:00

abstract：:The continued convergence of electronics and photonics on the chip scale can benefit from the voltage control of optical polarization for applications in communications, signal processing and sensing. It is challenging, however, to electrically manipulate the polarization state of light in planar optical waveguides. H...

journal_title：Nature communications

authors： Xu Q,Chen L,Wood MG,Sun P,Reano RM

更新日期：2014-11-12 00:00:00

abstract：:Acoustic waves, capable of transmitting through optically opaque objects, have been widely used in biomedical imaging, industrial sensing and particle manipulation. High-fidelity wave front shaping is essential to further improve performance in these applications. An acoustic analog to the successful spatial light mod...

journal_title：Nature communications

authors： Ma Z,Melde K,Athanassiadis AG,Schau M,Richter H,Qiu T,Fischer P

更新日期：2020-09-10 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Lee CH,Kang TH,Godon O,Watanabe M,Delidakis G,Gillis CM,Sterlin D,Hardy D,Cogné M,Macdonald LE,Murphy AJ,Tu N,Lee J,McDaniel JR,Makowski E,Tessier PM,Meyer AS,Bruhns P,Georgiou G

更新日期：2019-11-26 00:00:00

abstract：:Stable water isotope records from Antarctica are key for our understanding of Quaternary climate variations. However, the exact quantitative interpretation of these important climate proxy records in terms of surface temperature, ice sheet height and other climatic changes is still a matter of debate. Here we report r...

journal_title：Nature communications

authors： Werner M,Jouzel J,Masson-Delmotte V,Lohmann G

更新日期：2018-08-30 00:00:00

abstract：:URu2Si2 is one of the most enigmatic strongly correlated electron systems and offers a fertile testing ground for new concepts in condensed matter science. In spite of >30 years of intense research, no consensus on the order parameter of its low-temperature hidden-order phase exists. A strong magnetic field transforms...

journal_title：Nature communications

authors： Knafo W,Duc F,Bourdarot F,Kuwahara K,Nojiri H,Aoki D,Billette J,Frings P,Tonon X,Lelièvre-Berna E,Flouquet J,Regnault LP

更新日期：2016-10-20 00:00:00

abstract：:The assembly of actin filaments into distinct cytoskeletal structures plays a critical role in cell physiology, but how proteins localize differentially to these structures within a shared cytoplasm remains unclear. Here, we show that the actin-binding domains of accessory proteins can be sensitive to filament conform...

journal_title：Nature communications

authors： Harris AR,Jreij P,Belardi B,Joffe AM,Bausch AR,Fletcher DA

更新日期：2020-11-25 00:00:00

abstract：:Metals and polymers are dissimilar materials in terms of their physicochemical properties, but complementary in terms of functionality. As a result, metal-organic structures can introduce a wealth of novel applications in small-scale robotics. However, current fabrication techniques are unable to process three-dimensi...

journal_title：Nature communications

authors： Alcântara CCJ,Landers FC,Kim S,De Marco C,Ahmed D,Nelson BJ,Pané S

更新日期：2020-11-24 00:00:00

abstract：:Semiconductur nano- and micropillars represent a promising platform for hybrid nanodevices. Their ability to couple to a broad variety of nanomechanical, acoustic, charge, spin, excitonic, polaritonic, or electromagnetic excitations is utilized in fields as diverse as force sensing or optoelectronics. In order to full...

journal_title：Nature communications

authors： Doster J,Hoenl S,Lorenz H,Paulitschke P,Weig EM

更新日期：2019-11-20 00:00:00

abstract：:Environmental challenges to plants typically entail retardation of vegetative growth and delay or cessation of flowering. Here we report a link between the flowering time regulator, GIGANTEA (GI), and adaptation to salt stress that is mechanistically based on GI degradation under saline conditions, thus retarding flow...

journal_title：Nature communications

authors： Kim WY,Ali Z,Park HJ,Park SJ,Cha JY,Perez-Hormaeche J,Quintero FJ,Shin G,Kim MR,Qiang Z,Ning L,Park HC,Lee SY,Bressan RA,Pardo JM,Bohnert HJ,Yun DJ

更新日期：2013-01-01 00:00:00

abstract：:The cell cytosol is crowded with high concentrations of many different biomacromolecules, which is difficult to mimic in bottom-up synthetic cell research and limits the functionality of existing protocellular platforms. There is thus a clear need for a general, biocompatible, and accessible tool to more accurately em...

journal_title：Nature communications

authors： Altenburg WJ,Yewdall NA,Vervoort DFM,van Stevendaal MHME,Mason AF,van Hest JCM

更新日期：2020-12-08 00:00:00

abstract：:A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20006-5. ...

journal_title：Nature communications

authors： Escalera-Zamudio M,Golden M,Gutiérrez B,Thézé J,Keown JR,Carrique L,Bowden TA,Pybus OG

更新日期：2020-11-23 00:00:00

abstract：:Mammalian and Drosophila genomes are partitioned into topologically associating domains (TADs). Although this partitioning has been reported to be functionally relevant, it is unclear whether TADs represent true physical units located at the same genomic positions in each cell nucleus or emerge as an average of numero...

journal_title：Nature communications

authors： Ulianov SV,Zakharova VV,Galitsyna AA,Kos PI,Polovnikov KE,Flyamer IM,Mikhaleva EA,Khrameeva EE,Germini D,Logacheva MD,Gavrilov AA,Gorsky AS,Nechaev SK,Gelfand MS,Vassetzky YS,Chertovich AV,Shevelyov YY,Razin SV

更新日期：2021-01-04 00:00:00