Genetic Variations of NLR family genes in Behcet's Disease.

abstract：:The South American Monsoon System (SAMS) is generally considered to be highly sensitive to Northern Hemisphere (NH) temperature variations on multi-centennial timescales. The direct influence of solar forcing on moisture convergence in global monsoon systems on the other hand, while well explored in modeling studies, ...

journal_title：Scientific reports

authors： Novello VF,Vuille M,Cruz FW,Stríkis NM,de Paula MS,Edwards RL,Cheng H,Karmann I,Jaqueto PF,Trindade RI,Hartmann GA,Moquet JS

更新日期：2016-04-21 00:00:00

abstract：:PCR inhibitors in clinical specimens negatively affect the sensitivity of diagnostic PCR and RT-PCR or may even cause false-negative results. To overcome PCR inhibition, increase the sensitivity of the assays and simplify the detection protocols, simple methods based on quantitative nested real-time PCR and RT-PCR wer...

journal_title：Scientific reports

authors： Cai D,Behrmann O,Hufert F,Dame G,Urban G

更新日期：2018-02-21 00:00:00

abstract：:Somatostatin (SST)-positive interneurons in the anterior cingulate cortex (ACC) play important roles in neuronal diseases, memory and cognitive functions. However, their development in the ACC remains unclear. Using postnatal day 3 (P3) to P45 GIN mice, we found that most of the intrinsic membrane properties of SST in...

journal_title：Scientific reports

authors： Pan G,Yang JM,Hu XY,Li XM

更新日期：2016-06-20 00:00:00

abstract：:Drug delivery by topical application has higher patient acceptance and lower morbidity than intraocular injection, but many ophthalmic treatments are unable to enter the eye or reach the posterior segment after topical application. The first stage towards posterior segment delivery after topical application is ocular ...

journal_title：Scientific reports

authors： Begum G,Leigh T,Courtie E,Moakes R,Butt G,Ahmed Z,Rauz S,Logan A,Blanch RJ

更新日期：2020-07-16 00:00:00

abstract：:Temperature-modulated space-charge-limited-current spectroscopy (TMSCLC) is applied to quantitatively evaluate the density of trap states in the band-gap with high energy resolution of semiconducting hybrid lead halide perovskite single crystals. Interestingly multicomponent deep trap states were observed in the pure ...

journal_title：Scientific reports

authors： Pospisil J,Zmeskal O,Nespurek S,Krajcovic J,Weiter M,Kovalenko A

更新日期：2019-03-04 00:00:00

abstract：:Web search tools are widely used by the general public to obtain health-related information, and analysis of search data is often suggested for public health monitoring. We analyzed popularity of searches related to smell loss and taste loss, recently listed as symptoms of COVID-19. Searches on sight loss and hearing ...

journal_title：Scientific reports

authors： Asseo K,Fierro F,Slavutsky Y,Frasnelli J,Niv MY

更新日期：2020-11-25 00:00:00

abstract：:Pluripotent cells can be subdivided into two distinct states, the naïve and the primed state, the latter being further advanced on the path of differentiation. There are substantial differences in the regulation of pluripotency between human and mouse, and in humans only stem cells that resemble the primed state in mo...

journal_title：Scientific reports

authors： Ernst M,Abu Dawud R,Kurtz A,Schotta G,Taher L,Fuellen G

更新日期：2015-01-21 00:00:00

abstract：:Five selected carbazole derivatives, namely carbazole, 3,6-dibromocarbazole, 2-hydroxycarbazole, 1,2,3,4-tetrahydrocarbazole and 9-(2-ethylhexyl)carbazole-3,6-dicarboxaldehyde were investigated for their inhibitive effects on Desulfovibrio vulgaris (D. vulgaris) induced corrosion of mild steel and in 1 M HCl medium us...

journal_title：Scientific reports

authors： Nwankwo HU,Olasunkanmi LO,Ebenso EE

更新日期：2017-05-26 00:00:00

abstract：:C4.4A is a modular glycolipid-anchored Ly6/uPAR/α-neurotoxin multidomain protein that exhibits a prominent membrane-associated expression in stratified squamous epithelia. C4.4A is also expressed in various solid cancer lesions, where high expression levels often are correlated to poor prognosis. Circumstantial eviden...

journal_title：Scientific reports

authors： Kriegbaum MC,Jacobsen B,Füchtbauer A,Hansen GH,Christensen IJ,Rundsten CF,Persson M,Engelholm LH,Madsen AN,Di Meo I,Lund IK,Holst B,Kjaer A,Lærum OD,Füchtbauer EM,Ploug M

更新日期：2016-05-12 00:00:00

abstract：:Escherichia coli and Salmonella Enteritidis are foodborne pathogens forming challenging biofilms that contribute to their virulence, antimicrobial resistance, and survival on surfaces. Interspecies interactions occur between species in mixed biofilms promoting different outcomes to each species. Here we describe the i...

journal_title：Scientific reports

authors： Milho C,Silva MD,Alves D,Oliveira H,Sousa C,Pastrana LM,Azeredo J,Sillankorva S

更新日期：2019-12-03 00:00:00

abstract：:The Thoroughbred horse has played an important role in both sporting and economic aspects of society since the establishment of the breed in the 1700s. The extensive pedigree and phenotypic information available for the Thoroughbred horse population provides a unique opportunity to examine the effects of 300 years of ...

journal_title：Scientific reports

authors： Todd ET,Ho SYW,Thomson PC,Ang RA,Velie BD,Hamilton NA

更新日期：2018-04-18 00:00:00

abstract：:A novel one-pot synthesis of tri-substituted purines and the discovery of purine analogues with trypanocidal activity are reported. The reaction is initiated by a metal-free oxidative coupling of primary alkoxides and diaminopyrimidines with Schiff base formation and subsequent annulation in the presence of large N,N-...

journal_title：Scientific reports

authors： Pineda de las Infantas y Villatoro MJ,Unciti-Broceta JD,Contreras-Montoya R,Garcia-Salcedo JA,Gallo Mezo MA,Unciti-Broceta A,Diaz-Mochon JJ

更新日期：2015-03-16 00:00:00

abstract：:Cancer cells accumulate somatic mutations as result of DNA damage, inaccurate repair and other mechanisms. Different genetic instability processes result in characteristic non-random patterns of DNA mutations, also known as mutational signatures. We developed mutSignatures, an integrated R-based computational framewor...

journal_title：Scientific reports

authors： Fantini D,Vidimar V,Yu Y,Condello S,Meeks JJ

更新日期：2020-10-26 00:00:00

abstract：:Breast cancer is a heterogeneous disease consisting of several subtypes. Among these subtypes, triple negative breast cancer is particularly difficult to treat. This is due to a lack of understanding of the mechanisms behind the disease, and consequently a lack of druggable targets. PAK4 plays critical roles in cell s...

journal_title：Scientific reports

authors： Rane C,Senapedis W,Baloglu E,Landesman Y,Crochiere M,Das-Gupta S,Minden A

更新日期：2017-02-15 00:00:00

abstract：:Charge density wave (CDW), the periodic modulation of the electronic charge density, will open a gap on the Fermi surface that commonly leads to decreased or vanishing conductivity. On the other hand superconductivity, a commonly believed competing order, features a Fermi surface gap that results in infinite conductiv...

journal_title：Scientific reports

authors： Zhu X,Ning W,Li L,Ling L,Zhang R,Zhang J,Wang K,Liu Y,Pi L,Ma Y,Du H,Tian M,Sun Y,Petrovic C,Zhang Y

更新日期：2016-06-02 00:00:00

abstract：:Changes in litterfall dynamics and soil properties due to anthropogenic or natural perturbations have important implications to soil carbon (C) and nutrient cycling via microbial pathway. Here we determine soil microbial responses to contrasting types of litter inputs (leaf vs. fine woody litter) and nitrogen (N) depo...

journal_title：Scientific reports

authors： Sun XL,Zhao J,You YM,Jianxin Sun O

更新日期：2016-01-14 00:00:00

abstract：:We use satellite gravity measurements in the Gravity Recovery and Climate Experiment (GRACE) to estimate terrestrial water storage (TWS) change in the continental United States (US) from 2003 to 2012, and establish a GRACE-based Hydrological Drought Index (GHDI) for drought monitoring. GRACE-inferred TWS exhibits oppo...

journal_title：Scientific reports

authors： Yi H,Wen L

更新日期：2016-01-27 00:00:00

abstract：:Whole genome sequencing (WGS) can elucidate Mycobacterium tuberculosis (Mtb) transmission patterns but more data is needed to guide its use in high-burden settings. In a household-based TB transmissibility study in Peru, we identified a large MIRU-VNTR Mtb cluster (148 isolates) with a range of resistance phenotypes, ...

journal_title：Scientific reports

authors： Dixit A,Freschi L,Vargas R,Calderon R,Sacchettini J,Drobniewski F,Galea JT,Contreras C,Yataco R,Zhang Z,Lecca L,Kolokotronis SO,Mathema B,Farhat MR

更新日期：2019-04-03 00:00:00

abstract：:Photonic integrated circuits for photonic computing open up the possibility for the realization of ultrahigh-speed and ultra wide-band signal processing with compact size and low power consumption. Differential equations model and govern fundamental physical phenomena and engineering systems in virtually any field of ...

journal_title：Scientific reports

authors： Yang T,Dong J,Lu L,Zhou L,Zheng A,Zhang X,Chen J

更新日期：2014-07-04 00:00:00

abstract：:Cover crops (plants grown in an agricultural rotation between cash crops) can significantly improve soil quality via sequestering carbon, retaining nutrients, decreasing soil erosion, and maintaining belowground biodiversity. However, little is known about the effects of such plants upon soil structure. The aim of the...

journal_title：Scientific reports

authors： Bacq-Labreuil A,Crawford J,Mooney SJ,Neal AL,Ritz K

更新日期：2019-05-16 00:00:00

abstract：:Accumulating evidence implies that both AKT1 and GABAA receptor (GABAAR) subunit genes are involved in schizophrenia pathogenesis. Activated Akt promotes GABAergic neuron differentiation and increases GABAAR expression on the plasma membrane. To elucidate the role of Akt1 in modulating GABAergic functions and schizoph...

journal_title：Scientific reports

authors： Chang CY,Chen YW,Wang TW,Lai WS

更新日期：2016-09-12 00:00:00

abstract：:Despite strong evidence for NMDA receptor (NMDAR) hypofunction as an underlying factor for cognitive disorders, the precise roles of various NMDAR subtypes remains unknown. The GluN2C-containing NMDARs exhibit unique biophysical properties and expression pattern, and lower expression of GluN2C subunit has been reporte...

journal_title：Scientific reports

authors： Gupta SC,Ravikrishnan A,Liu J,Mao Z,Pavuluri R,Hillman BG,Gandhi PJ,Stairs DJ,Li M,Ugale RR,Monaghan DT,Dravid SM

更新日期：2016-12-06 00:00:00

abstract：:Fowl cholera is a serious, highly contagious disease caused by the bacterium Pasteurella multocida (P. multocida) in a range of avian species and is characterized by an acute form of septicaemia. The pathogenic mechanism of chicken lung injury caused by the bacterium is unclear. Therefore, P. multocida Q (a reference ...

journal_title：Scientific reports

authors： Li W,Tang Q,Dai N,Feng W,Xie C,Cheng G,Liu X,Zhang W,Hu X,Gu C

更新日期：2020-04-14 00:00:00

abstract：:Molybdenum disulfide (MoS2) has been attracting much attentions due to its excellent electrical and optical properties. We report here the synthesis of large-scale and uniform MoS2 nanosheets with vertically standing morphology using chemical vapor deposition method. TEM observations clearly reveal the growth mechanis...

journal_title：Scientific reports

authors： Li H,Wu H,Yuan S,Qian H

更新日期：2016-02-18 00:00:00

abstract：:Nanofluids using nanoencapsulated Phase Change Materials (nePCM) allow increments in both the thermal conductivity and heat capacity of the base fluid. Incremented heat capacity is produced by the melting enthalpy of the nanoparticles core. In this work two important advances in this nanofluid type are proposed and ex...

journal_title：Scientific reports

authors： Navarrete N,Gimeno-Furio A,Mondragon R,Hernandez L,Cabedo L,Cordoncillo E,Julia JE

更新日期：2017-12-14 00:00:00

abstract：:A modular p-phosphonated calix[4]arene vesicle (PCV) loaded with paclitaxel (PTX) and conjugated with folic acid as a cancer targeting ligand has been prepared using a thin film-sonication method. It has a pH-responsive capacity to trigger the release of the encapsulated PTX payload under mildly acidic conditions. PTX...

journal_title：Scientific reports

authors： Mo J,Eggers PK,Yuan ZX,Raston CL,Lim LY

更新日期：2016-03-24 00:00:00

abstract：:This study analyzed hourly mass concentration observations of PM2.5 (particulate matters with diameter less than 2.5 μm) at 512 stations in China from December 2013 to May 2015. We found that the mean concentrations of PM2.5 during the winter and spring of 2015 Dec. 2014 to Feb. 2015 and Mar. 2015 to May 2015) decreas...

journal_title：Scientific reports

authors： Wang X,Wang K,Su L

更新日期：2016-11-02 00:00:00

abstract：:HAUSP (herpes virus-associated ubiquitin specific protease, known as ubiquitin specific protease 7), one of DUBs, regulates the dynamics of the p53 and Mdm2 network in response to DNA damage by deubiquitinating both p53 and its E3 ubiquitin ligase, Mdm2. Its concerted action increases the level of functional p53 by pr...

journal_title：Scientific reports

authors： Lim KH,Park JJ,Gu BH,Kim JO,Park SG,Baek KH

更新日期：2015-08-04 00:00:00

abstract：:Understanding how a species utilises its habitat, and the processes that give rise to its movements and patterns of space use, is critical for its conservation. Southern Ground-hornbills Bucorvus leadbeateri are listed as Endangered in South Africa, as a result of habitat loss and persecution. The National Species Rec...

journal_title：Scientific reports

authors： Combrink L,Combrink HJ,Botha AJ,Downs CT

更新日期：2020-10-01 00:00:00

abstract：:Organic nanofibers have found various applications in optoelectronic devices. In such devices, exciton diffusion is a major aspect concerning their efficiency. In the case of singlet excitons, Förster transfer is the mechanism responsible for this process. Temperature and morphology are factors known to influence exci...

journal_title：Scientific reports

authors： de Sousa LE,da Silva Filho DA,de Sousa RT Jr,de Oliveira Neto PH

更新日期：2018-09-19 00:00:00