Paclitaxel-loaded phosphonated calixarene nanovesicles as a modular drug delivery platform.

abstract：:The simplest and most commonly used acoustic levitator is comprised of a transmitter and an opposing reflecting surface. This type of device, however, is only able to levitate objects along one direction, at distances multiple of half of a wavelength. In this work, we show how a customised reflective acoustic metamate...

journal_title：Scientific reports

authors： Polychronopoulos S,Memoli G

更新日期：2020-03-06 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Bosshard M,Aprigliano R,Gattiker C,Palibrk V,Markkanen E,Backe PH,Pellegrino S,Raymond FL,Froyen G,Altmeyer M,Bjørås M,Dianov GL,Loon BV

更新日期：2018-04-12 00:00:00

abstract：:Single nucleotide variations (SNVs) can result in loss or gain of protein functional sites. We analyzed the effects of SNVs on enzyme active sites, ligand binding sites, and various types of post translational modification (PTM) sites. We found that, for most types of protein functional sites, the SNV pattern differs ...

journal_title：Scientific reports

authors： Pan Y,Yan C,Hu Y,Fan Y,Pan Q,Wan Q,Torcivia-Rodriguez J,Mazumder R

更新日期：2017-02-08 00:00:00

abstract：:The serum macrophage inhibitory cytokine-1 (MIC-1) levels are elevated in some inflammatory conditions and cancers. We thus compared the levels of biliary and serum MIC-1 and conventional tumour markers between 23 biliary tract cancer (BTC) patients (malignant group) and 29 benign biliary disease patients (benign grou...

journal_title：Scientific reports

authors： Sugimoto M,Takagi T,Konno N,Suzuki R,Asama H,Watanabe K,Nakamura J,Waragai Y,Kikuchi H,Takasumi M,Sato Y,Hikichi T,Ohira H

更新日期：2017-08-23 00:00:00

abstract：:Convenient drug-resistance testing of viral mutants is indispensable to effective treatment of viral infection. We developed a novel fluorometric assay for phenotypic differentiation of drug-resistant mutants of human immunodeficiency virus-I protease (HIV-PR) which uses enzymatic and peptide-specific fluorescence (FL...

journal_title：Scientific reports

authors： Zhu Q,Yu Z,Kabashima T,Yin S,Dragusha S,El-Mahdy AF,Ejupi V,Shibata T,Kai M

更新日期：2015-05-19 00:00:00

abstract：:Transition metals are a group of elements widespread in aquatic environments that can be hazardous when concentrations exceeding threshold values. Due to insufficient data, criteria maximum concentrations (CMCs) of only seven transition metals for protecting aquatic life have been recommended by the USEPA. Hence, it i...

journal_title：Scientific reports

authors： Wang Y,Wu F,Mu Y,Zeng EY,Meng W,Zhao X,Giesy JP,Feng C,Wang P,Liao H,Chen C

更新日期：2016-03-03 00:00:00

abstract：:Fossils of the sponge Angulosuspongia sinensis from calcareous mudstones of the middle and upper part of the Kaili Formation (Cambrian Stage 5) in the Jianhe area of Guizhou province, South China, exhibit an apparently reticulate pattern, characteristic of the Vauxiidae. Energy Dispersive X-Ray Spectrometry (EDS) and ...

journal_title：Scientific reports

authors： Yang XL,Zhao YL,Babcock LE,Peng J

更新日期：2017-02-21 00:00:00

abstract：:College students, as a large part of young adults, are a vulnerable group to several risky behaviors including smoking and drug abuse. This study aimed to utilize and to compare count regression models to identify correlates of cigarette smoking among college students. This was a cross-sectional study conducted on stu...

journal_title：Scientific reports

authors： Sharareh P,Leili T,Abbas M,Jalal P,Ali G

更新日期：2020-06-01 00:00:00

abstract：:The understanding of the relationship between topology and behaviour in interconnected networks would allow to charac- terise and predict behaviour in many real complex networks since both are usually not simultaneously known. Most previous studies have focused on the relationship between topology and synchronisation....

journal_title：Scientific reports

authors： Baptista MS,Szmoski RM,Pereira RF,Pinto SE

更新日期：2016-03-04 00:00:00

abstract：:Pulsed electromagnetic fields (PEMFs) have been considered a potential treatment modality for fracture healing, however, the mechanism of their action remains unclear. Mammalian target of rapamycin (mTOR) signaling may affect osteoblast proliferation and differentiation. This study aimed to assess the osteogenic diffe...

journal_title：Scientific reports

authors： Ferroni L,Gardin C,Dolkart O,Salai M,Barak S,Piattelli A,Amir-Barak H,Zavan B

更新日期：2018-03-23 00:00:00

abstract：:The subtle mechanisms by which protein-DNA interactions remain functional across a wide range of temperatures are largely unknown. In this work, we manually curated available information relating fully sequenced archaeal genomes with organism growth temperatures. We built a motif that represents the core promoter of e...

journal_title：Scientific reports

authors： Aptekmann AA,Nadra AD

更新日期：2018-01-22 00:00:00

abstract：:Performing everyday actions requires fine postural control, which is a major focus of functional rehabilitation programs. Among the various range of training methods likely to improve balance and postural stability, motor imagery practice (MIP) yielded promising results. Transcranial direct current stimulation (tDCS) ...

journal_title：Scientific reports

authors： Saruco E,Di Rienzo F,Nunez-Nagy S,Rubio-Gonzalez MA,Jackson PL,Collet C,Saimpont A,Guillot A

更新日期：2017-03-28 00:00:00

abstract：:Influence maximization is the problem of finding the set of nodes of a network that maximizes the size of the outbreak of a spreading process occurring on the network. Solutions to this problem are important for strategic decisions in marketing and political campaigns. The typical setting consists in the identificatio...

journal_title：Scientific reports

authors： Erkol Ş,Castellano C,Radicchi F

更新日期：2019-10-22 00:00:00

abstract：:During development, cell division often generates two daughters with different developmental fates. Distinct daughter identities can result from the physical polarity and size asymmetry itself, as well as the subsequent activation of distinct fate programmes in each daughter. Asymmetric divisions are a feature of the ...

journal_title：Scientific reports

authors： Ding SS,Woollard A

更新日期：2017-06-14 00:00:00

abstract：:Phagocytosis is a process in which target cells or particles are engulfed and taken up by other cells, typically professional phagocytes; this process is crucial in many physiological processes and disease states. The detection of targets for phagocytosis is directed by a complex repertoire of cell surface receptors. ...

journal_title：Scientific reports

authors： Schulz D,Severin Y,Zanotelli VRT,Bodenmiller B

更新日期：2019-02-13 00:00:00

abstract：:Early diagnosis of Parkinson's disease (PD) remains a challenge to date. New evidence highlights the potential clinical value of circulating trace amines (TAs) in early-stage PD and their involvement in disease progression. A new ultra performance chromatography mass spectrometry (UPLC-MS/MS) method was developed to q...

journal_title：Scientific reports

authors： D'Andrea G,Pizzolato G,Gucciardi A,Stocchero M,Giordano G,Baraldi E,Leon A

更新日期：2019-04-16 00:00:00

abstract：:The primary method for measuring brain metabolism in humans is positron emission tomography (PET) imaging using the tracer 18F-fluorodeoxyglucose (FDG). Standardized uptake value ratios (SUVR) are commonly calculated from FDG-PET images to examine intra- and inter-subject effects. Various reference regions are used in...

journal_title：Scientific reports

authors： Nugent S,Croteau E,Potvin O,Castellano CA,Dieumegarde L,Cunnane SC,Duchesne S

更新日期：2020-06-09 00:00:00

abstract：:First identified in The Netherlands in 2004, human coronavirus NL63 (HCoV-NL63) was found to cause worldwide infections. Patients infected by HCoV-NL63 are typically young children with upper and lower respiratory tract infection, presenting with symptoms including croup, bronchiolitis, and pneumonia. Unfortunately, t...

journal_title：Scientific reports

authors： Wang F,Chen C,Tan W,Yang K,Yang H

更新日期：2016-03-07 00:00:00

abstract：:Plutella xylostella has become the major lepidopteran pest of Brassica owing to its strong ability of resistance development to a wide range of insecticides. Destruxin A, a mycotoxin of entomopathogenic fungus, Metarhizium anisopliae, has broad-spectrum insecticidal effects. However, the interaction mechanism of destr...

journal_title：Scientific reports

authors： Shakeel M,Xu X,Xu J,Zhu X,Li S,Zhou X,Yu J,Xu X,Hu Q,Yu X,Jin F

更新日期：2017-09-08 00:00:00

abstract：:Tuneable pressure effects associated with changing interlayer distances in two-dimensional graphene oxide (GO)/reduced GO (rGO) layers are demonstrated through monitoring the changes in the spin-crossover (SCO) temperature (T 1/2) of [Fe(Htrz)2(trz)](BF4) nanoparticles (NPs) incorporated in the interlayer spaces of th...

journal_title：Scientific reports

authors： Sekimoto Y,Ohtani R,Nakamura M,Koinuma M,Lindoy LF,Hayami S

更新日期：2017-09-22 00:00:00

abstract：:Phaseonium is a three-level Λ quantum system, in which a coherent microwave and an optical control (pump) beams can be used to actively modulate the dielectric response. Here we propose a new metamaterial structure comprising of a periodic array of triangular phaseonium metamolecules arranged as a trefoil. We present ...

journal_title：Scientific reports

authors： Nguyen DM,Soci C,Ooi CH

更新日期：2016-02-16 00:00:00

abstract：:The killer toxin K1 is a virally encoded fungal A/B toxin acting by disrupting plasma membrane integrity. The connection of α and β constitutes a critical feature for toxin biology and for decades the formation of three disulphide bonds linking the major toxin subunits was accepted as status quo. Due to the absence of...

journal_title：Scientific reports

authors： Gier S,Lermen M,Schmitt MJ,Breinig F

更新日期：2019-09-11 00:00:00

abstract：:Either hardness or toughness has been the core interest in scientific exploration and technological pursuit for a long time. However, it is still a big challenge to enhance the hardness and toughness at the same time, since the improvement of one side is always at the expense of the other one. Here, we have succeeded ...

journal_title：Scientific reports

authors： Yang L,Zhang K,Wen M,Hou Z,Gong C,Liu X,Hu C,Cui X,Zheng W

更新日期：2017-08-24 00:00:00

abstract：:The plasmodial CTP:phosphocholine cytidylyltransferase (PfCCT) is a promising antimalarial target, which can be inhibited to exploit the need for increased lipid biosynthesis during the erythrocytic life stage of Plasmodium falciparum. Notable structural and regulatory differences of plasmodial and mammalian CCTs offe...

journal_title：Scientific reports

authors： Marton L,Hajdú F,Nagy GN,Kucsma N,Szakács G,Vértessy BG

更新日期：2018-06-12 00:00:00

abstract：:Encapsulation is essential to protect the air-sensitive components of organic light-emitting diodes (OLEDs) such as active layers and cathode electrodes. In this study, hybrid zirconium inorganic/organic nanolaminates were fabricated using remote plasma enhanced atomic layer deposition (PEALD) and molecular layer depo...

journal_title：Scientific reports

authors： Chen Z,Wang H,Wang X,Chen P,Liu Y,Zhao H,Zhao Y,Duan Y

更新日期：2017-01-06 00:00:00

abstract：:GPS-derived Total Electron Content (TEC) is an integrated quantity; hence it is difficult to relate the detection of ionospheric perturbations in TEC to a precise altitude. As TEC is weighted by the maximum ionospheric density, the corresponding altitude (hmF2) is, generally, assumed as the perturbation detection alti...

journal_title：Scientific reports

authors： Thomas D,Bagiya MS,Sunil PS,Rolland L,Sunil AS,Mikesell TD,Nayak S,Mangalampalli S,Ramesh DS

更新日期：2018-08-14 00:00:00

abstract：:The studies on the increasing incidence of thyroid abnormalities are scarce. The aim of this current study was to ascertain the effects of geographical region on thyroid abnormalities under the context of universal salt iodization (USI). We randomly selected 1255 participants residing in inland and 1248 in coast, with...

journal_title：Scientific reports

authors： Wang X,Mo Z,Mao G,Zhu W,Xing M,Li X,Wang Y,Wang Z,Lou X

更新日期：2021-01-13 00:00:00

abstract：:The occurrence of toxic metals in the aquatic environment is as caused by a variety of contaminations which makes difficulty in the concentration prediction. In this study, conventional methods of back-propagation neural network (BPNN) and nonlinear autoregressive network with exogenous inputs (NARX) were applied as b...

journal_title：Scientific reports

authors： Li P,Hua P,Gui D,Niu J,Pei P,Zhang J,Krebs P

更新日期：2020-08-10 00:00:00

abstract：:PICK1 (protein interacting with C-kinase 1) is a peripheral membrane protein that interacts with diverse membrane proteins. PICK1 has been shown to regulate the clustering and membrane localization of synaptic receptors such as AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptors, metabotropic glutama...

journal_title：Scientific reports

authors： Xu J,Wang N,Luo JH,Xia J

更新日期：2016-02-12 00:00:00

abstract：:The effect of free mate choice on the relative magnitude of fitness benefits has been examined among various species. The majority of the data show significant fitness benefits of mating with partners of an individual's own choice, highlighting elevated behavioral compatibility between partners with free mate choice. ...

journal_title：Scientific reports

authors： Sorokowski P,Groyecka A,Karwowski M,Manral U,Kumar A,Niemczyk A,Marczak M,Misiak M,Sorokowska A,Huanca T,Conde E,Wojciszke B,Pawłowski B

更新日期：2017-08-31 00:00:00