Abstract：
PURPOSE:To determine the response of retinal vessels to differing durations of flicker light (FL) stimulation. METHODS:We recorded retinal arterial and venous vessel dilation to 12.5 Hz FL provocation of varying duration (5, 7, 10, and 20 seconds) in 12 healthy young individuals (age range, 26-45 years). All participants underwent a full ocular examination including IOP and blood pressure measurements. RESULTS:Maximum dilation (MD) did not show a significant dependence on flicker duration in arteries, whereas maximum constriction (MC) did. In veins, however, MD significantly increased with flicker duration. Approximately 80% to 90% of MD in arteries is reached within 10 seconds of FL stimulation. CONCLUSIONS:The vast majority of arterial dilatory capacity is reached within 10 seconds of FL stimulation even though venous dilation continues strongly. Since MC of arteries shows a significant dependence on flicker duration, measurements at two different durations can provide more information about the retinal vascular system than at a single flicker duration alone.
journal_name
Invest Ophthalmol Vis Scijournal_title
Investigative ophthalmology & visual scienceauthors
Heitmar R,Summers RJdoi
10.1167/iovs.15-17089subject
Has Abstractpub_date
2015-11-01 00:00:00pages
7581-8issue
12eissn
0146-0404issn
1552-5783pii
2474152journal_volume
56pub_type
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journal_title：Investigative ophthalmology & visual science
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journal_title：Investigative ophthalmology & visual science
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