Genetic and phylogenetic analysis of a new porcine circovirus type 2 (PCV2) strain in China.

Abstract:

:Porcine circovirus type 2 (PCV2) is the etiological agent associated with several pig diseases that are collectively referred to as porcine circovirus-associated disease (PCVAD). Unfortunately, PCV2 has had a serious economic impact on the swine industry. In this study, we report the genome sequence of a novel PCV2 isolate (JS2015) identified in pigs in Jiang Su, China. The complete DNA sequence was 1766 nucleotides long with an A+T content of 52.7%. It lacked a guanine (G) at nucleotide position 1045 compared to other reference PCV2 strains with a sequence length of 1766 nucleotides. Genetic characterization and phylogenetic analysis showed that the isolate JS2015 was most closely related to members of the PCV2d (AY181946) lineage. Our data provide insight into the epidemiology of porcine circovirus and may facilitate further study of the origin and evolution of PCV2.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Zhang D,He K,Wen L,Fan H

doi

10.1007/s00705-015-2615-8

subject

Has Abstract

pub_date

2015-12-01 00:00:00

pages

3149-51

issue

12

eissn

0304-8608

issn

1432-8798

pii

10.1007/s00705-015-2615-8

journal_volume

160

pub_type

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