Some biological and physico-chemical properties of egg drop syndrome (EDS) avian adenovirus strain B8/78.

Abstract:

:The EDS adenovirus produced either in the allantoic cavity of embryonated duck eggs (A0 virus) or in chicken embryo liver cell cultures (TC0 virus) were comparatively studied by gradient ultracentrifugation in CsCl. The A0 viral particles banded at densities of 1.36 and 1.31 g/ml, whereas, the TC0 viral particle were found at densities of 1.33 and 1.31 g/ml, respectively. The heavy populations contained infectious and hemagglutinating particles if they were not pelleted and sonicated before gradient ultracentrifugation. Pelleting or sonicating the viral particles resulted in loss of hemagglutinating activity of the heavy populations. The light particles were hemagglutinating but not infectious regardless of the previous treatment. The pH- and heat-sensitivity of the B8/78 virus strain was similar to those described for CEL0 (FAV-1) adenovirus (5). The B8/78 virus strain replicated well in tissue cultures of chicken and goose origin causing the formation of intranuclear inclusion bodies in the infected cells.

journal_name

Arch Virol

journal_title

Archives of virology

authors

Zsák L,Kisary J

doi

10.1007/BF01314574

subject

Has Abstract

pub_date

1981-01-01 00:00:00

pages

211-9

issue

3-4

eissn

0304-8608

issn

1432-8798

journal_volume

68

pub_type

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