Abstract:
:A developmental approach to public health focuses attention on better nourishing girls and young women, especially those of low socio-economic status, to improve mothers' nutrition and thereby the health of future generations. There have been significant advances in the behavioural sciences that may allow us to understand and support dietary change in young women and their children in ways that have not previously been possible. This paper describes some of these advances and aims to show how they inform this new approach to public health. The first of these has been to work out what is effective in supporting behaviour change, which has been achieved by careful and detailed analysis of behaviour change techniques used by practitioners in intervention, and of the effectiveness of these in supporting change. There is also a new understanding of the role that social and physical environments play in shaping our behaviours, and that behaviour is influenced by automatic processes and 'habits' as much as by reflective processes and rational decisions. To be maximally effective, interventions therefore have to address both influences on behaviour. An approach developed in Southampton aims to motivate, support and empower young women to make better food choices, but also to change the culture in which those choices are being made. Empowerment is the basis of the new public health. An empowered public demand for better access to better food can go a long way towards improving maternal, infant and family nutrition, and therefore the health of generations to come.
journal_name
J Dev Orig Health Disjournal_title
Journal of developmental origins of health and diseaseauthors
Barker Mdoi
10.1017/S2040174415001312subject
Has Abstractpub_date
2015-10-01 00:00:00pages
428-33issue
5eissn
2040-1744issn
2040-1752pii
S2040174415001312journal_volume
6pub_type
杂志文章,评审abstract::Preterm birth (delivery <37 weeks of gestation) is associated with impaired glomerular capillary growth in neonates; if this persists, it may be a contributing factor in the increased risk of hypertension and chronic kidney disease in people born preterm. Therefore, in this study, we aimed to determine the long-term i...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174420001208
更新日期:2020-12-10 00:00:00
abstract::The identification of early-life determinants of overweight is crucial to start early prevention. As weight gain accelerates between 2 and 6 years, we studied the association between diet quality in children aged 3 years and the change in BMI and overweight incidence in the following 7 years. From the Dutch GECKO Dren...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S204017442000118X
更新日期:2020-12-11 00:00:00
abstract::Footprints in Time: The Longitudinal Study of Indigenous Children (LSIC) is a national study of 1759 Australian Aboriginal and Torres Strait Islander children living across urban, regional and remote areas of Australia. The study is in its 11th wave of annual data collection, having collected extensive data on topics ...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S204017441800017X
更新日期:2019-02-01 00:00:00
abstract::Hepatitis B and hepatitis C (HBV/HCV) are important global public health concerns. We aimed to evaluate the association between maternal HBV/HCV carrier status and long-term offspring neurological hospitalisations. A population-based cohort analysis compared the risk for long-term childhood neurological hospitalisatio...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174420001397
更新日期:2021-01-21 00:00:00
abstract::Renin is essential for renal development and in adult kidneys vitamin D deficiency increases renin gene expression. We aimed to determine whether maternal vitamin D deficiency upregulates fetal renal renin expression, and if this is sustained. We also examined growth and the long-term renal effects in offspring on a n...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174413000342
更新日期:2013-10-01 00:00:00
abstract::The evidence underpinning the developmental origins of health and disease (DOHaD) is overwhelming. As the emphasis shifts more towards interventions and the translational strategies for disease prevention, it is important to capitalize on collaboration and knowledge sharing to maximize opportunities for discovery and ...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174416000167
更新日期:2016-10-01 00:00:00
abstract::Iron deficiency is common in pregnant and lactating women and is associated with reduced cognitive development of the offspring. Since iron affects lipid metabolism, the availability of fatty acids, particularly the polyunsaturated fatty acids required for early neural development, was investigated in the offspring of...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174419000552
更新日期:2020-06-01 00:00:00
abstract::Rates of obesity are increasing in women of child bearing age with negative impacts on maternal and offspring health. Emerging evidence suggests in utero origins of respiratory health in offspring of obese mothers but mechanisms are unknown. Changes in maternal cortisol levels are one potential factor as cortisol leve...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174414000312
更新日期:2014-10-01 00:00:00
abstract::Associations between different forms of malnutrition and environmental conditions, including water, sanitation and hygiene (WASH), may contribute towards persistently poor child health, growth and cognitive development. Experiencing poor nutrition in utero or during early childhood is furthermore associated with chron...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174419000898
更新日期:2021-02-01 00:00:00
abstract::Although numerous studies have been conducted to examine the causal factors of childhood obesity, the implications of intrauterine oxidative stress on early postnatal adiposity development remain to be elucidated. The Universiti Sains Malaysia Birth Cohort Study aimed to investigate the effects of prenatal oxidative s...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S204017441300055X
更新日期:2014-04-01 00:00:00
abstract::The risk for many chronic diseases appears to be mediated in part by birth weight. Among Aboriginal Canadians, the prevalence of end-stage renal disease and cardiovascular disease risk is disproportionately high, largely because of elevated diabetes prevalence. The relationships between birth weight (and other potenti...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174412000724
更新日期:2013-04-01 00:00:00
abstract::Maternal undernutrition is known to adversely impact fetal health and development. Insults experienced in utero alter development of the fetus as it adapts to microenvironment stressors, leading to growth restriction and subsequent low birth weight. Infants born small for gestational age have significantly increased r...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174416000106
更新日期:2016-10-01 00:00:00
abstract::Antenatal exposure of the fetus to inflammation may alter postnatal organ development. In our previous work, we demonstrated that the fetal liver is involved in the systemic inflammation associated with chorioamnionitis, leading to metabolic changes. On the basis of these findings, we hypothesized that chorioamnioniti...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174412000049
更新日期:2012-04-01 00:00:00
abstract::Bisphenol-A (BPA) is a widely used endocrine-disrupting chemical. Prenatal exposure to BPA is known to affect birth weight, but its impact on the cardiovascular system has not been studied in detail. In this study, we investigated the effects of prenatal BPA treatment and its interaction with postnatal overfeeding on ...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S204017441600057X
更新日期:2017-02-01 00:00:00
abstract::Breast milk constitutes one of the most important sources of postnatal microbes. However, the influence of perinatal factors on the milk microbiome is still poorly understood. The aim of our study was to assess the impact of mode of delivery on the microbiome composition and diversity present in breast milk of healthy...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174415001397
更新日期:2016-02-01 00:00:00
abstract::Obesity and its complications occur at alarming rates worldwide. Epidemiological data have associated perinatal conditions, such as malnutrition, with the development of some disorders, such as obesity, dyslipidemia, diabetes, and cardiovascular diseases, in childhood and adulthood. Exclusive breastfeeding has been as...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174420000410
更新日期:2020-10-01 00:00:00
abstract::Predisposition to offspring metabolic dysfunction due to poor maternal nutrition differs with the developmental stage at exposure. Post-weaning nutrition also influences offspring phenotype in either adverse or beneficial ways. We studied a well-established rat maternal protein-restriction model to determine whether p...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174415001051
更新日期:2015-08-01 00:00:00
abstract::In this study, diabetes mellitus (DM) was induced in Wistar rats during pregnancy and maintained in the postpartum period (PP) and we evaluated systolic blood pressure (SBP), glomerular filtration rate (GFR) and renal immunohistochemical and morphometric studies from different groups: G1 (non-pregnant control rats), G...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174417000605
更新日期:2018-02-01 00:00:00
abstract::Adipose tissue (AT) dysfunction links obesity of any cause with cardiometabolic disease, but whether early-life nutritional deficiency can program adipocyte dysfunction independently of obesity is untested. In 3-5-month-old juvenile microswine offspring exposed to isocaloric perinatal maternal protein restriction (MPR...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174412000232
更新日期:2012-06-01 00:00:00
abstract::Associations between maternal salivary testosterone at 36 weeks' gestation with birth weight and infant weight gain through 6 months of age were examined in a group of 49 healthy, pregnant women and their offspring. The diurnal decline of maternal testosterone was conserved in late pregnancy, and levels showed signifi...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174413000135
更新日期:2013-08-01 00:00:00
abstract::The association between lower birth weight and increased disease risk in adulthood has drawn attention to the physiological processes that shape the gestational environment. We implement genome-wide transcriptional profiling of maternal blood samples to identify subsets of genes and associated transcription control pa...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174419000175
更新日期:2019-12-01 00:00:00
abstract::An estimated 200 million children worldwide fail to meet their development potential due to poverty, poor health and unstimulating environments. Missing developmental milestones has lasting effects on adult human capital. Africa has a large burden of risk factors for poor child development. The objective of this paper...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174415001427
更新日期:2016-04-01 00:00:00
abstract::Prenatal glucocorticoids, commonly used in women at risk of preterm delivery, can predispose the newborn to disease in later life. Since male reproductive function is likely to reflect testis development during fetal life, we studied the effects of prenatal glucocorticoids on two key intra-testicular factors that play...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174416000118
更新日期:2016-08-01 00:00:00
abstract::Early-life intervention to reduce obesity and poor dental health through early-life nutrition will improve health outcomes in later life. This study examined the prevalence of overweight and obesity and visual dental decay in 4-year old children in New Zealand between 2013 and 2017, and the impact of a nutrition and p...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174418000788
更新日期:2019-06-01 00:00:00
abstract::Despite the interest in the relationship of fetal exposures to adult cardiovascular disease, few studies have examined indicators of adult fatty liver disease as an outcome. Previous results are inconsistent, and indicate possible variation by sex. Adult liver enzymes [γ-glutamyl transferase (GGT), alanine transaminas...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174416000635
更新日期:2017-04-01 00:00:00
abstract::The objectives of this study were to describe the prevalence of cigarette use and water pipe smoking in Jordanian university students and to analyze differences in determinants between cigarette smokers and non-smokers. A cross-sectional questionnaire was administered to a random sample of 400 students (18-24 years, 5...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174411000122
更新日期:2011-06-01 00:00:00
abstract::The consumption of fructose has increased in children and adolescents and is partially responsible for the high incidence of metabolic diseases. The lifestyle during postnatal development can result in altered metabolic programming, thereby impairing the reproductive system and fertility during adulthood. Therefore, t...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174420001385
更新日期:2021-01-14 00:00:00
abstract::Intrauterine factors important for cognitive development, such as birth weight, chorionicity and umbilical cord characteristics were investigated. A total of 663 twin pairs completed the Wechsler Intelligence Scale for Children-Revised and scores were available for Performance, Verbal and Total Intelligence Quotient (...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174413000287
更新日期:2013-12-01 00:00:00
abstract::This study aimed to assess the association between maternal-isolated oligohydramnios (IO) and offspring long-term neurological complications. A population-based retrospective cohort study was conducted, including all births at a single tertiary medical center in Israel between the years 1991 and 2014. Multiple pregnan...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174419000795
更新日期:2020-12-01 00:00:00
abstract::The hypothesis was that maternal intake of the antioxidant alpha-lipoid acid (ALA), during the developmental period of the hypothalamic orexigenic neurons, causes a permanent beneficial effect in offspring metabolism. Pregnant Wistar rats were fed with standard diet (food) + ALA (0.4% wt/wt) from day 14 of gestation t...
journal_title:Journal of developmental origins of health and disease
pub_type: 杂志文章
doi:10.1017/S2040174420001178
更新日期:2020-12-11 00:00:00