Indicators of fetal growth and adult liver enzymes: the Bogalusa Heart Study and the Cardiovascular Risk in Young Finns Study.

abstract：:The aim of this study was to observe the association between maternal undernutrition and metabolic risk indicators in newborns at birth. Fifty-nine expectant mothers between 28 and 40 weeks of gestation were included after obtaining their informed consent. Mothers were divided into undernourished, normally nourished a...

journal_title：Journal of developmental origins of health and disease

authors： Shaikh F,Basit A,Hakeem R,Fawwad A,Hussain A

更新日期：2015-08-01 00:00:00

abstract：:The principles embodied by the Developmental Origins of Health and Disease (DOHaD) view of 'life history' trajectory are increasingly underpinned by biological data arising from molecular-based epigenomic and transcriptomic studies. Although a number of 'omic' platforms are now routinely and widely used in biology and...

journal_title：Journal of developmental origins of health and disease

authors： Pleasants AB,Wake GC,Shorten PR,Hassell-Sweatman CZ,McLean CA,Holbrook JD,Gluckman PD,Sheppard AM

更新日期：2015-02-01 00:00:00

abstract：:The Developmental Origins of Health and Disease (DOHaD) framework aims to understand how environmental exposures in early life shape lifecycle health. Our understanding and the ability to prevent poor health outcomes and enrich for resiliency remain limited, in part, because exposure-outcome relationships are complex ...

journal_title：Journal of developmental origins of health and disease

authors： Abdul-Hussein A,Kareem A,Tewari S,Bergeron J,Briollais L,Challis JRG,Davidge ST,Delrieux C,Fortier I,Goldowitz D,Nepomnaschy P,Wazana A,Connor KL

更新日期：2020-08-04 00:00:00

abstract：:The evolution of birth weight (BW), birth length (BL), and gestational age at delivery (GAD) and their correlation with various maternal sociodemographic variables were studied in Chilean newborns from years 1996 to 2017. A slight decrease in the mean values of these perinatal outcomes was observed; however, their ris...

journal_title：Journal of developmental origins of health and disease

authors： Mardones F,Acuña J

更新日期：2020-12-04 00:00:00

abstract：:Tobacco smoke has both carcinogenic effects and anti-estrogenic properties and its inconsistent association with breast cancer risk in observational studies may be because of these competing effects across the lifecourse. We conducted a prospective study of prenatal smoke exposure, childhood household smoke exposure, ...

journal_title：Journal of developmental origins of health and disease

authors： Terry MB,Schaefer CA,Flom JD,Wei Y,Tehranifar P,Liao Y,Buka S,Michels KB

更新日期：2011-12-01 00:00:00

abstract：:Although numerous studies have been conducted to examine the causal factors of childhood obesity, the implications of intrauterine oxidative stress on early postnatal adiposity development remain to be elucidated. The Universiti Sains Malaysia Birth Cohort Study aimed to investigate the effects of prenatal oxidative s...

journal_title：Journal of developmental origins of health and disease

authors： Loy SL,Sirajudeen KN,Hamid Jan JM

更新日期：2014-04-01 00:00:00

abstract：:Associations between maternal salivary testosterone at 36 weeks' gestation with birth weight and infant weight gain through 6 months of age were examined in a group of 49 healthy, pregnant women and their offspring. The diurnal decline of maternal testosterone was conserved in late pregnancy, and levels showed signifi...

journal_title：Journal of developmental origins of health and disease

authors： Voegtline KM,Costigan KA,Kivlighan KT,Henderson JL,DiPietro JA

更新日期：2013-08-01 00:00:00

abstract：:This study was undertaken to compare amino acid concentrations in maternal and newborn infants' serum in normal pregnancy and two groups of obese women who were born themselves with normal and small for gestational age (SGA) birth weight. Maternal cholesterol, lipoproteins concentrations and maternal and infants amino...

journal_title：Journal of developmental origins of health and disease

authors： Tsyvian PB,Bashmakova NV,Kovtun OP,Makarenko LV,Pestryaeva LA

更新日期：2015-08-01 00:00:00

abstract：:Depression and anxiety in the antenatal period are of public health concern given potential adverse effects for both mother and infant. Both are under-researched in the first trimester of pregnancy, especially in Africa. We examine the prevalence of first trimester antenatal depression and anxiety in a cohort of South...

journal_title：Journal of developmental origins of health and disease

authors： Redinger S,Norris SA,Pearson RM,Richter L,Rochat T

更新日期：2018-02-01 00:00:00

abstract：:With brown adipose tissue (BAT) becoming a possible therapeutic target to counteract obesity, the prenatal environment could represent a critical window to modify BAT function and browning of white AT. We investigated if levels of uncoupling protein 1 (UCP1) and UCP1-mediated thermogenesis are altered in offspring exp...

journal_title：Journal of developmental origins of health and disease

authors： Bytautiene Prewit E,Porter C,La Rosa M,Bhattarai N,Yin H,Gamble P,Kechichian T,Sidossis LS

更新日期：2018-08-01 00:00:00

abstract：:As the resident macrophage of the central nervous system, microglia are thought to contribute to Alzheimer's disease (AD) pathology through lack of neuroprotection. The role of immune dysfunction in AD may be due to disruption of regulatory signals for the activation of microglia that may occur early in development. W...

journal_title：Journal of developmental origins of health and disease

authors： vonderEmbse AN,Hu Q,DeWitt JC

更新日期：2017-08-01 00:00:00

abstract：:An appropriate foetal cardiovascular (CV) response to reduced substrate supply (e.g. oxygen or other nutrients) is vital for growth and development, and may impact on CV control. The prevailing nutritional environment and associated CV changes may influence subsequent CV responses to challenges during late gestation, ...

journal_title：Journal of developmental origins of health and disease

authors： Cleal JK,Bagby S,Hanson MA,Gardiner HM,Green LR

更新日期：2010-02-01 00:00:00

abstract：:The identification of early-life determinants of overweight is crucial to start early prevention. As weight gain accelerates between 2 and 6 years, we studied the association between diet quality in children aged 3 years and the change in BMI and overweight incidence in the following 7 years. From the Dutch GECKO Dren...

journal_title：Journal of developmental origins of health and disease

authors： Vinke PC,Luitjens MHHS,Blijleven KA,Navis G,Kromhout D,Corpeleijn E

更新日期：2020-12-11 00:00:00

abstract：:This study aimed to assess the association between maternal-isolated oligohydramnios (IO) and offspring long-term neurological complications. A population-based retrospective cohort study was conducted, including all births at a single tertiary medical center in Israel between the years 1991 and 2014. Multiple pregnan...

journal_title：Journal of developmental origins of health and disease

authors： Dorot A,Wainstock T,Sheiner E,Walfisch A,Landau D,Harlev A

更新日期：2020-12-01 00:00:00

abstract：:Hepatitis B and hepatitis C (HBV/HCV) are important global public health concerns. We aimed to evaluate the association between maternal HBV/HCV carrier status and long-term offspring neurological hospitalisations. A population-based cohort analysis compared the risk for long-term childhood neurological hospitalisatio...

journal_title：Journal of developmental origins of health and disease

authors： Yoles I,Sheiner E,Abu-Freha N,Wainstock T

更新日期：2021-01-21 00:00:00

abstract：:Extremely premature birth is associated with a permanent disruption of energy metabolism. The underlying mechanisms are poorly understood. The oxidative stress induced by parenteral nutrition (PN) during the first week of life is suspected to reprogram energy metabolism in the liver. Full-term male Hartley guinea pigs...

journal_title：Journal of developmental origins of health and disease

authors： Teixeira V,Guiraut C,Mohamed I,Lavoie JC

更新日期：2020-08-03 00:00:00

abstract：:The evidence underpinning the developmental origins of health and disease (DOHaD) is overwhelming. As the emphasis shifts more towards interventions and the translational strategies for disease prevention, it is important to capitalize on collaboration and knowledge sharing to maximize opportunities for discovery and ...

journal_title：Journal of developmental origins of health and disease

authors： Prescott SL,Allen K,Armstrong K,Collins C,Dickinson H,Gardiner K,Jacka F,Jasoni C,Moore T,Moritz KM,Muhlhausler B,Siero W,Sim K,Nanan R,Saffery R,Singh G,Vickers MH,Craig JM

更新日期：2016-10-01 00:00:00

abstract：:Prenatal exposure to persistent organic pollutants (POPs) has been associated with the development of metabolic syndrome-related diseases in offspring. According to epidemiological studies, father's transmission of environmental effects in addition to mother's can influence offspring health. Moreover, maternal prenata...

journal_title：Journal of developmental origins of health and disease

authors： Navarro P,Dalvai M,Charest PL,Herst PM,Lessard M,Marcotte B,Mitchell PL,Leblanc N,Kimmins S,Trasler J,MacFarlane AJ,Marette A,Bailey JL,Jacques H

更新日期：2019-09-16 00:00:00

abstract：:Antenatal exposure of the fetus to inflammation may alter postnatal organ development. In our previous work, we demonstrated that the fetal liver is involved in the systemic inflammation associated with chorioamnionitis, leading to metabolic changes. On the basis of these findings, we hypothesized that chorioamnioniti...

journal_title：Journal of developmental origins of health and disease

authors： Vlassaks E,Gavilanes AW,Bieghs V,Reinartz A,Gassler N,Van Gorp PJ,Gijbels MJ,Bekers O,Zimmermann LJ,Pillow JJ,Polglase GR,Nitsos I,Newnham JP,Kallapur SG,Jobe AH,Shiri-Sverdlov R,Kramer BW

更新日期：2012-04-01 00:00:00

abstract：:Preterm birth affects over 12% of all infants born in the US yet the biology of early delivery remains unclear, including whether epigenetic mechanisms are involved. We examined associations of maternal and umbilical cord blood long interspersed nuclear element-1 (LINE-1) DNA methylation with length of gestation and o...

journal_title：Journal of developmental origins of health and disease

authors： Burris HH,Rifas-Shiman SL,Baccarelli A,Tarantini L,Boeke CE,Kleinman K,Litonjua AA,Rich-Edwards JW,Gillman MW

更新日期：2012-06-01 00:00:00

abstract：:Ilex paraguariensis (yerba mate) has a beneficial effect in the management of obesity. Here, we studied the effects of yerba mate on hypothalamic changes in leptin and insulin signalling, oxidative stress and liver morphology and metabolism in postnatal early overfeeding (EO) Wistar rats. To induce EO, the litter size...

journal_title：Journal of developmental origins of health and disease

authors： Conceição EP,Kaezer AR,Peixoto-Silva N,Felzenszwalb I,de Oliveira E,Moura EG,Lisboa PC

更新日期：2017-02-01 00:00:00

abstract：:Placental weight is a valuable indicator of its function, predicting both pregnancy outcome and lifelong health. Population-based centile charts of weight-for-gestational-age and parity are useful for identifying extremes of placental weight but fail to consider maternal size. To address this deficit, a multiple regre...

journal_title：Journal of developmental origins of health and disease

authors： Wallace JM,Agard JP,Horgan GW

更新日期：2019-10-07 00:00:00

abstract：:In this study, diabetes mellitus (DM) was induced in Wistar rats during pregnancy and maintained in the postpartum period (PP) and we evaluated systolic blood pressure (SBP), glomerular filtration rate (GFR) and renal immunohistochemical and morphometric studies from different groups: G1 (non-pregnant control rats), G...

journal_title：Journal of developmental origins of health and disease

authors： França-Silva N,Reis NG,Santos PF,Balbi APC

更新日期：2018-02-01 00:00:00

abstract：:Maternal undernutrition is known to adversely impact fetal health and development. Insults experienced in utero alter development of the fetus as it adapts to microenvironment stressors, leading to growth restriction and subsequent low birth weight. Infants born small for gestational age have significantly increased r...

journal_title：Journal of developmental origins of health and disease

authors： Schlegel RN,Moritz KM,Paravicini TM

更新日期：2016-10-01 00:00:00

abstract：:The development and life performance of 404 high-producing Holstein dairy cows was studied from birth onwards and during two lactations. The management, environment and parental genetics of the cows were known in detail. Cluster analysis identified four performance 'types': high-yielding (HY) cows and persistently hig...

journal_title：Journal of developmental origins of health and disease

authors： Astiz S,Gonzalez-Bulnes A,Sebastian F,Fargas O,Cano I,Cuesta P

更新日期：2014-10-01 00:00:00

abstract：:Associations between different forms of malnutrition and environmental conditions, including water, sanitation and hygiene (WASH), may contribute towards persistently poor child health, growth and cognitive development. Experiencing poor nutrition in utero or during early childhood is furthermore associated with chron...

journal_title：Journal of developmental origins of health and disease

authors： Momberg DJ,Ngandu BC,Voth-Gaeddert LE,Cardoso Ribeiro K,May J,Norris SA,Said-Mohamed R

更新日期：2021-02-01 00:00:00

abstract：:Here we analyze the outcomes of unlimited access to a low-energy (LE) diet in dams and their offspring. At 3 weeks' gestation, pregnant Wistar rats were divided into two groups: (1) the control group received a normoenergetic diet; and (2) the experimental group received the LE diet. In dams, lactation outcomes, food ...

journal_title：Journal of developmental origins of health and disease

authors： do Nascimento E,de Santana Muniz G,das Graças de Santana Muniz M,de Souza Alexandre L,da Rocha LS,Leandro CG,de Castro RM,Bolaños-Jimenez F

更新日期：2014-02-01 00:00:00

abstract：:Rates of obesity are increasing in women of child bearing age with negative impacts on maternal and offspring health. Emerging evidence suggests in utero origins of respiratory health in offspring of obese mothers but mechanisms are unknown. Changes in maternal cortisol levels are one potential factor as cortisol leve...

journal_title：Journal of developmental origins of health and disease

authors： de Vries A,Reynolds RM,Seckl JR,van der Wal M,Bonsel GJ,Vrijkotte TG

更新日期：2014-10-01 00:00:00

abstract：:Breast milk constitutes one of the most important sources of postnatal microbes. However, the influence of perinatal factors on the milk microbiome is still poorly understood. The aim of our study was to assess the impact of mode of delivery on the microbiome composition and diversity present in breast milk of healthy...

journal_title：Journal of developmental origins of health and disease

authors： Cabrera-Rubio R,Mira-Pascual L,Mira A,Collado MC

更新日期：2016-02-01 00:00:00

abstract：:Footprints in Time: The Longitudinal Study of Indigenous Children (LSIC) is a national study of 1759 Australian Aboriginal and Torres Strait Islander children living across urban, regional and remote areas of Australia. The study is in its 11th wave of annual data collection, having collected extensive data on topics ...

journal_title：Journal of developmental origins of health and disease

authors： Salmon M,Skelton F,Thurber KA,Bennetts Kneebone L,Gosling J,Lovett R,Walter M

更新日期：2019-02-01 00:00:00