Maternal aging affects life performance of progeny in a Holstein dairy cow model.

abstract：:The risk for many chronic diseases appears to be mediated in part by birth weight. Among Aboriginal Canadians, the prevalence of end-stage renal disease and cardiovascular disease risk is disproportionately high, largely because of elevated diabetes prevalence. The relationships between birth weight (and other potenti...

journal_title：Journal of developmental origins of health and disease

authors： Oster RT,Luyckx VA,Toth EL

更新日期：2013-04-01 00:00:00

abstract：:Hypertension (HTN) remains a common complication after kidney transplantation among paediatric patients. Although low birth weight (LBW) has been implicated as an important risk factor for cardiovascular diseases, its effect on transplantation patients has not yet been addressed. It is essential to determine whether c...

journal_title：Journal of developmental origins of health and disease

authors： Santos LB,Borges LM,Souza LV,Felipe CR,Medina-Pestana JO,Franco MDC

更新日期：2020-02-01 00:00:00

abstract：:Antenatal exposure of the fetus to inflammation may alter postnatal organ development. In our previous work, we demonstrated that the fetal liver is involved in the systemic inflammation associated with chorioamnionitis, leading to metabolic changes. On the basis of these findings, we hypothesized that chorioamnioniti...

journal_title：Journal of developmental origins of health and disease

authors： Vlassaks E,Gavilanes AW,Bieghs V,Reinartz A,Gassler N,Van Gorp PJ,Gijbels MJ,Bekers O,Zimmermann LJ,Pillow JJ,Polglase GR,Nitsos I,Newnham JP,Kallapur SG,Jobe AH,Shiri-Sverdlov R,Kramer BW

更新日期：2012-04-01 00:00:00

abstract：:Our objective was to investigate associations of body size (birth weight and body mass index (BMI)) and growth in height, body fat (adiposity) and lean mass during childhood and adolescence, with risk markers for diabetes in young South Asian adults. We studied 357 men and women aged 21 years from the Pune Children's ...

journal_title：Journal of developmental origins of health and disease

authors： Kumaran K,Lubree H,Bhat DS,Joshi S,Joglekar C,Yajnik P,Bhave S,Pandit A,Fall CHD,Yajnik CS

更新日期：2020-08-05 00:00:00

abstract：:Early-life intervention to reduce obesity and poor dental health through early-life nutrition will improve health outcomes in later life. This study examined the prevalence of overweight and obesity and visual dental decay in 4-year old children in New Zealand between 2013 and 2017, and the impact of a nutrition and p...

journal_title：Journal of developmental origins of health and disease

authors： Rush E,Kirk M,Parmar P,Young L,Obolonkin V

更新日期：2019-06-01 00:00:00

abstract：:The effect of maternal Ramadan-type fasting (RTF) on the outcome of pregnancy, kidney development and nephron number in male rat offspring was investigated in current study. Pregnant rats were given food and water ad libitum during pregnancy (control) or restricted for 16 h per day (RTF). Kidney structure was examined...

journal_title：Journal of developmental origins of health and disease

authors： Mohany M,Ashton N,Harrath AH,Nyengaard JR,Alomar SY,Alwasel S

更新日期：2018-06-01 00:00:00

abstract：:The objectives of this study were to describe the prevalence of cigarette use and water pipe smoking in Jordanian university students and to analyze differences in determinants between cigarette smokers and non-smokers. A cross-sectional questionnaire was administered to a random sample of 400 students (18-24 years, 5...

journal_title：Journal of developmental origins of health and disease

authors： Farajat M,Hoving C,De Vries H

更新日期：2011-06-01 00:00:00

abstract：:Associations between different forms of malnutrition and environmental conditions, including water, sanitation and hygiene (WASH), may contribute towards persistently poor child health, growth and cognitive development. Experiencing poor nutrition in utero or during early childhood is furthermore associated with chron...

journal_title：Journal of developmental origins of health and disease

authors： Momberg DJ,Ngandu BC,Voth-Gaeddert LE,Cardoso Ribeiro K,May J,Norris SA,Said-Mohamed R

更新日期：2021-02-01 00:00:00

abstract：:Approximately 10% of all babies worldwide are born preterm, and preterm birth is the leading cause of perinatal mortality in developed countries. Although preterm birth is associated with adverse short- and long-term health outcomes, it is not yet clear whether this relationship is causal. Rather, there is evidence th...

journal_title：Journal of developmental origins of health and disease

authors： Harding JE,Derraik JG,Berry MJ,Jaquiery AL,Alsweiler JM,Cormack BE,Bloomfield FH

更新日期：2013-06-01 00:00:00

abstract：:An adverse early life environment can increase the risk of metabolic and other disorders later in life. Genetic variation can modify an individual's susceptibility to these environmental challenges. These gene by environment interactions are important, but difficult, to dissect. The nucleus is the primary organelle wh...

journal_title：Journal of developmental origins of health and disease

authors： Jacobson E,Vickers MH,Perry JK,O'Sullivan JM

更新日期：2018-06-01 00:00:00

abstract：:In this study, diabetes mellitus (DM) was induced in Wistar rats during pregnancy and maintained in the postpartum period (PP) and we evaluated systolic blood pressure (SBP), glomerular filtration rate (GFR) and renal immunohistochemical and morphometric studies from different groups: G1 (non-pregnant control rats), G...

journal_title：Journal of developmental origins of health and disease

authors： França-Silva N,Reis NG,Santos PF,Balbi APC

更新日期：2018-02-01 00:00:00

abstract：:Prenatal diethylstilbestrol (DES) exposure is associated with increased risk of hormonally mediated cancers and other medical conditions. We evaluated the association between DES and risk of pancreatic cancer and pancreatic disorders, type 2 diabetes, and gallbladder disease, which may be involved with this malignancy...

journal_title：Journal of developmental origins of health and disease

authors： Troisi R,Hyer M,Titus L,Palmer JR,Hatch EE,Huo D,Aagaard KM,Strohsnitter WC,Hoover RN

更新日期：2020-10-28 00:00:00

abstract：:The evidence underpinning the developmental origins of health and disease (DOHaD) is overwhelming. As the emphasis shifts more towards interventions and the translational strategies for disease prevention, it is important to capitalize on collaboration and knowledge sharing to maximize opportunities for discovery and ...

journal_title：Journal of developmental origins of health and disease

authors： Prescott SL,Allen K,Armstrong K,Collins C,Dickinson H,Gardiner K,Jacka F,Jasoni C,Moore T,Moritz KM,Muhlhausler B,Siero W,Sim K,Nanan R,Saffery R,Singh G,Vickers MH,Craig JM

更新日期：2016-10-01 00:00:00

abstract：:The association between lower birth weight and increased disease risk in adulthood has drawn attention to the physiological processes that shape the gestational environment. We implement genome-wide transcriptional profiling of maternal blood samples to identify subsets of genes and associated transcription control pa...

journal_title：Journal of developmental origins of health and disease

authors： McDade TW,Kuzawa CW,Borja J,Arevalo JMG,Miller G,Cole SW

更新日期：2019-12-01 00:00:00

abstract：:Rates of obesity are increasing in women of child bearing age with negative impacts on maternal and offspring health. Emerging evidence suggests in utero origins of respiratory health in offspring of obese mothers but mechanisms are unknown. Changes in maternal cortisol levels are one potential factor as cortisol leve...

journal_title：Journal of developmental origins of health and disease

authors： de Vries A,Reynolds RM,Seckl JR,van der Wal M,Bonsel GJ,Vrijkotte TG

更新日期：2014-10-01 00:00:00

abstract：:Embryonal rhabdomyosarcoma is one of the major defined histologic variants of rhabdomyosarcoma that is mainly reported in children. The histologic appearance of this neoplastic entity recapitulates normal myogenesis. The tumor cells variably exhibit the different cellular phases of myogenesis ranging from undifferenti...

journal_title：Journal of developmental origins of health and disease

authors： Lav R,Heera R,Cherian LM

更新日期：2015-06-01 00:00:00

abstract：:A life-course approach to reduction of risk of non-communicable diseases (NCD) suggests that early-life interventions may be more effective than lifestyle modifications in middle age. Knowledge translation to develop understanding of the Developmental Origins of Health and Disease (DOHaD) within the community offers t...

journal_title：Journal of developmental origins of health and disease

authors： Bay JL,Mora HA,Sloboda DM,Morton SM,Vickers MH,Gluckman PD

更新日期：2012-12-01 00:00:00

abstract：:Obesity and its complications occur at alarming rates worldwide. Epidemiological data have associated perinatal conditions, such as malnutrition, with the development of some disorders, such as obesity, dyslipidemia, diabetes, and cardiovascular diseases, in childhood and adulthood. Exclusive breastfeeding has been as...

journal_title：Journal of developmental origins of health and disease

authors： Souza LL,de Moura EG,Lisboa PC

更新日期：2020-10-01 00:00:00

abstract：:Pregnant women, children under 2 and the first thousand days of life have been principal targets for Developmental Origins of Health and Disease interventions. This paradigm has been criticized for laying responsibility for health outcomes on pregnant women and mothers and through the thousand days focus inadvertently...

journal_title：Journal of developmental origins of health and disease

authors： Pentecost M,Ross FC,Macnab A

更新日期：2018-02-01 00:00:00

abstract：:Predisposition to offspring metabolic dysfunction due to poor maternal nutrition differs with the developmental stage at exposure. Post-weaning nutrition also influences offspring phenotype in either adverse or beneficial ways. We studied a well-established rat maternal protein-restriction model to determine whether p...

journal_title：Journal of developmental origins of health and disease

authors： Bautista CJ,Guzmán C,Rodríguez-González GL,Zambrano E

更新日期：2015-08-01 00:00:00

abstract：:Although abundant evidence exists that adverse events during pregnancy lead to chronic conditions, there is limited information on the impact of acute insults such as sepsis. This study tested the hypothesis that impaired fetal development leads to altered organ responses to a septic insult in both male and female adu...

journal_title：Journal of developmental origins of health and disease

authors： Khazaee R,Vinokurtseva A,McCaig LA,Yamashita C,Hardy DB,Arany E,Veldhuizen RAW

更新日期：2020-12-23 00:00:00

abstract：:Postnatal and antenatal depression present significant public health concerns. Current opinion on the use of these terms is noted. Previous research findings demonstrate that detrimental effects of untreated maternal depression/anxiety are potentially severe and impact on the whole family; longer-term effects on child...

journal_title：Journal of developmental origins of health and disease

authors： Hall P

更新日期：2012-08-01 00:00:00

abstract：:Preterm birth affects over 12% of all infants born in the US yet the biology of early delivery remains unclear, including whether epigenetic mechanisms are involved. We examined associations of maternal and umbilical cord blood long interspersed nuclear element-1 (LINE-1) DNA methylation with length of gestation and o...

journal_title：Journal of developmental origins of health and disease

authors： Burris HH,Rifas-Shiman SL,Baccarelli A,Tarantini L,Boeke CE,Kleinman K,Litonjua AA,Rich-Edwards JW,Gillman MW

更新日期：2012-06-01 00:00:00

abstract：:An appropriate foetal cardiovascular (CV) response to reduced substrate supply (e.g. oxygen or other nutrients) is vital for growth and development, and may impact on CV control. The prevailing nutritional environment and associated CV changes may influence subsequent CV responses to challenges during late gestation, ...

journal_title：Journal of developmental origins of health and disease

authors： Cleal JK,Bagby S,Hanson MA,Gardiner HM,Green LR

更新日期：2010-02-01 00:00:00

abstract：:The hypothesis that vitamin content of the diet during gestation alters macronutrient choice, food intake and the expression of serotonin receptors and proopiomelanocortin (POMC) in the hypothalamus of the offspring was investigated. Pregnant Wistar rats (n = 10/group) were fed the AIN-93G diet containing a multivitam...

journal_title：Journal of developmental origins of health and disease

authors： Szeto IM,Payne ME,Jahan-Mihan A,Duan J,Anderson GH

更新日期：2010-12-01 00:00:00

abstract：:Preterm birth (delivery <37 weeks of gestation) is associated with impaired glomerular capillary growth in neonates; if this persists, it may be a contributing factor in the increased risk of hypertension and chronic kidney disease in people born preterm. Therefore, in this study, we aimed to determine the long-term i...

journal_title：Journal of developmental origins of health and disease

authors： Sutherland MR,Malik W,Nguyen VB,Tran V,Polglase GR,Black MJ

更新日期：2020-12-10 00:00:00

abstract：:The consumption of fructose has increased in children and adolescents and is partially responsible for the high incidence of metabolic diseases. The lifestyle during postnatal development can result in altered metabolic programming, thereby impairing the reproductive system and fertility during adulthood. Therefore, t...

journal_title：Journal of developmental origins of health and disease

authors： Medaglia DSA,Vieira HR,Silveira SDS,Siervo GEML,Marcon MSDS,Mathias PCF,Fernandes GSA

更新日期：2021-01-14 00:00:00

abstract：:A developmental approach to public health focuses attention on better nourishing girls and young women, especially those of low socio-economic status, to improve mothers' nutrition and thereby the health of future generations. There have been significant advances in the behavioural sciences that may allow us to unders...

journal_title：Journal of developmental origins of health and disease

authors： Barker M

更新日期：2015-10-01 00:00:00

abstract：:Renin is essential for renal development and in adult kidneys vitamin D deficiency increases renin gene expression. We aimed to determine whether maternal vitamin D deficiency upregulates fetal renal renin expression, and if this is sustained. We also examined growth and the long-term renal effects in offspring on a n...

journal_title：Journal of developmental origins of health and disease

authors： Boyce AC,Palmer-Aronsten BJ,Kim MY,Gibson KJ

更新日期：2013-10-01 00:00:00

abstract：:Ilex paraguariensis (yerba mate) has a beneficial effect in the management of obesity. Here, we studied the effects of yerba mate on hypothalamic changes in leptin and insulin signalling, oxidative stress and liver morphology and metabolism in postnatal early overfeeding (EO) Wistar rats. To induce EO, the litter size...

journal_title：Journal of developmental origins of health and disease

authors： Conceição EP,Kaezer AR,Peixoto-Silva N,Felzenszwalb I,de Oliveira E,Moura EG,Lisboa PC

更新日期：2017-02-01 00:00:00