Adolescent understanding of DOHaD concepts: a school-based intervention to support knowledge translation and behaviour change.

abstract：:Adipose tissue (AT) dysfunction links obesity of any cause with cardiometabolic disease, but whether early-life nutritional deficiency can program adipocyte dysfunction independently of obesity is untested. In 3-5-month-old juvenile microswine offspring exposed to isocaloric perinatal maternal protein restriction (MPR...

journal_title：Journal of developmental origins of health and disease

authors： DuPriest EA,Kupfer P,Lin B,Sekiguchi K,Morgan TK,Saunders KE,Chatkupt TT,Denisenko ON,Purnell JQ,Bagby SP

更新日期：2012-06-01 00:00:00

abstract：:Androgens may directly modulate early ovarian follicular development in preantral stages and androgen excess before puberty may disrupt this physiological process. Therefore, the aim of this study was to investigate the dynamics of follicular morphology and circulating androgen and estradiol levels in prepubertal Wist...

journal_title：Journal of developmental origins of health and disease

authors： Paixão L,Velez LM,Santos BR,Tusset C,Lecke SB,Motta AB,Spritzer PM

更新日期：2016-08-01 00:00:00

abstract：:Despite the interest in the relationship of fetal exposures to adult cardiovascular disease, few studies have examined indicators of adult fatty liver disease as an outcome. Previous results are inconsistent, and indicate possible variation by sex. Adult liver enzymes [γ-glutamyl transferase (GGT), alanine transaminas...

journal_title：Journal of developmental origins of health and disease

authors： Harville EW,Chen W,Bazzano L,Oikonen M,Hutri-Kähönen N,Raitakari O

更新日期：2017-04-01 00:00:00

abstract：:Iron deficiency is common in pregnant and lactating women and is associated with reduced cognitive development of the offspring. Since iron affects lipid metabolism, the availability of fatty acids, particularly the polyunsaturated fatty acids required for early neural development, was investigated in the offspring of...

journal_title：Journal of developmental origins of health and disease

authors： Rees WD,Hay SM,Hayes HE,Stevens VJ,Gambling L,McArdle HJ

更新日期：2020-06-01 00:00:00

abstract：:The consumption of fructose has increased in children and adolescents and is partially responsible for the high incidence of metabolic diseases. The lifestyle during postnatal development can result in altered metabolic programming, thereby impairing the reproductive system and fertility during adulthood. Therefore, t...

journal_title：Journal of developmental origins of health and disease

authors： Medaglia DSA,Vieira HR,Silveira SDS,Siervo GEML,Marcon MSDS,Mathias PCF,Fernandes GSA

更新日期：2021-01-14 00:00:00

abstract：:Associations between maternal salivary testosterone at 36 weeks' gestation with birth weight and infant weight gain through 6 months of age were examined in a group of 49 healthy, pregnant women and their offspring. The diurnal decline of maternal testosterone was conserved in late pregnancy, and levels showed signifi...

journal_title：Journal of developmental origins of health and disease

authors： Voegtline KM,Costigan KA,Kivlighan KT,Henderson JL,DiPietro JA

更新日期：2013-08-01 00:00:00

abstract：:Breast milk constitutes one of the most important sources of postnatal microbes. However, the influence of perinatal factors on the milk microbiome is still poorly understood. The aim of our study was to assess the impact of mode of delivery on the microbiome composition and diversity present in breast milk of healthy...

journal_title：Journal of developmental origins of health and disease

authors： Cabrera-Rubio R,Mira-Pascual L,Mira A,Collado MC

更新日期：2016-02-01 00:00:00

abstract：:The evidence underpinning the developmental origins of health and disease (DOHaD) is overwhelming. As the emphasis shifts more towards interventions and the translational strategies for disease prevention, it is important to capitalize on collaboration and knowledge sharing to maximize opportunities for discovery and ...

journal_title：Journal of developmental origins of health and disease

authors： Prescott SL,Allen K,Armstrong K,Collins C,Dickinson H,Gardiner K,Jacka F,Jasoni C,Moore T,Moritz KM,Muhlhausler B,Siero W,Sim K,Nanan R,Saffery R,Singh G,Vickers MH,Craig JM

更新日期：2016-10-01 00:00:00

abstract：:Although abundant evidence exists that adverse events during pregnancy lead to chronic conditions, there is limited information on the impact of acute insults such as sepsis. This study tested the hypothesis that impaired fetal development leads to altered organ responses to a septic insult in both male and female adu...

journal_title：Journal of developmental origins of health and disease

authors： Khazaee R,Vinokurtseva A,McCaig LA,Yamashita C,Hardy DB,Arany E,Veldhuizen RAW

更新日期：2020-12-23 00:00:00

abstract：:Low birth weight and a rapid weight gain in early childhood may lead to an increased risk for developing cardiovascular disease later in life, such as hypertension and dyslipidaemia. In this study, we examined the associations between size at birth, relative weight gain in infancy and childhood with specific cardiovas...

journal_title：Journal of developmental origins of health and disease

authors： Musa MG,Kagura J,Pisa PT,Norris SA

更新日期：2016-04-01 00:00:00

abstract：:Approximately 10% of all babies worldwide are born preterm, and preterm birth is the leading cause of perinatal mortality in developed countries. Although preterm birth is associated with adverse short- and long-term health outcomes, it is not yet clear whether this relationship is causal. Rather, there is evidence th...

journal_title：Journal of developmental origins of health and disease

authors： Harding JE,Derraik JG,Berry MJ,Jaquiery AL,Alsweiler JM,Cormack BE,Bloomfield FH

更新日期：2013-06-01 00:00:00

abstract：:The evolution of birth weight (BW), birth length (BL), and gestational age at delivery (GAD) and their correlation with various maternal sociodemographic variables were studied in Chilean newborns from years 1996 to 2017. A slight decrease in the mean values of these perinatal outcomes was observed; however, their ris...

journal_title：Journal of developmental origins of health and disease

authors： Mardones F,Acuña J

更新日期：2020-12-04 00:00:00

abstract：:In this study, diabetes mellitus (DM) was induced in Wistar rats during pregnancy and maintained in the postpartum period (PP) and we evaluated systolic blood pressure (SBP), glomerular filtration rate (GFR) and renal immunohistochemical and morphometric studies from different groups: G1 (non-pregnant control rats), G...

journal_title：Journal of developmental origins of health and disease

authors： França-Silva N,Reis NG,Santos PF,Balbi APC

更新日期：2018-02-01 00:00:00

abstract：:Predisposition to offspring metabolic dysfunction due to poor maternal nutrition differs with the developmental stage at exposure. Post-weaning nutrition also influences offspring phenotype in either adverse or beneficial ways. We studied a well-established rat maternal protein-restriction model to determine whether p...

journal_title：Journal of developmental origins of health and disease

authors： Bautista CJ,Guzmán C,Rodríguez-González GL,Zambrano E

更新日期：2015-08-01 00:00:00

abstract：:An adverse early life environment can increase the risk of metabolic and other disorders later in life. Genetic variation can modify an individual's susceptibility to these environmental challenges. These gene by environment interactions are important, but difficult, to dissect. The nucleus is the primary organelle wh...

journal_title：Journal of developmental origins of health and disease

authors： Jacobson E,Vickers MH,Perry JK,O'Sullivan JM

更新日期：2018-06-01 00:00:00

abstract：:The developmental origins hypothesis suggests that morbidity and premature mortality arise, in part, from adverse exposures in utero and early in development. Evidence suggests a connection between early nutritional deficits and adult morbidity; however, the effects on mortality have been less well studied and previou...

journal_title：Journal of developmental origins of health and disease

authors： Saxton K,Falconi A,Goldman-Mellor S,Catalano R

更新日期：2013-02-01 00:00:00

abstract：:Associations between different forms of malnutrition and environmental conditions, including water, sanitation and hygiene (WASH), may contribute towards persistently poor child health, growth and cognitive development. Experiencing poor nutrition in utero or during early childhood is furthermore associated with chron...

journal_title：Journal of developmental origins of health and disease

authors： Momberg DJ,Ngandu BC,Voth-Gaeddert LE,Cardoso Ribeiro K,May J,Norris SA,Said-Mohamed R

更新日期：2021-02-01 00:00:00

abstract：:An estimated 200 million children worldwide fail to meet their development potential due to poverty, poor health and unstimulating environments. Missing developmental milestones has lasting effects on adult human capital. Africa has a large burden of risk factors for poor child development. The objective of this paper...

journal_title：Journal of developmental origins of health and disease

authors： Ford ND,Stein AD

更新日期：2016-04-01 00:00:00

abstract：:Renin is essential for renal development and in adult kidneys vitamin D deficiency increases renin gene expression. We aimed to determine whether maternal vitamin D deficiency upregulates fetal renal renin expression, and if this is sustained. We also examined growth and the long-term renal effects in offspring on a n...

journal_title：Journal of developmental origins of health and disease

authors： Boyce AC,Palmer-Aronsten BJ,Kim MY,Gibson KJ

更新日期：2013-10-01 00:00:00

abstract：:Adverse uterine environments caused by maternal stress (such as bacterial endotoxin) can alter programming of the fetal hypothalamic-pituitary-adrenal axis (HPAA) rendering offspring susceptible to various adulthood diseases. Thus, protection against this type of stress may be critical for ensuring offspring health. T...

journal_title：Journal of developmental origins of health and disease

authors： Fisher RE,Or'Rashid M,Quinton M,AlZahal O,Boermans HJ,McBride BW,Karrow NA

更新日期：2014-06-01 00:00:00

abstract：:Our objective was to investigate associations of body size (birth weight and body mass index (BMI)) and growth in height, body fat (adiposity) and lean mass during childhood and adolescence, with risk markers for diabetes in young South Asian adults. We studied 357 men and women aged 21 years from the Pune Children's ...

journal_title：Journal of developmental origins of health and disease

authors： Kumaran K,Lubree H,Bhat DS,Joshi S,Joglekar C,Yajnik P,Bhave S,Pandit A,Fall CHD,Yajnik CS

更新日期：2020-08-05 00:00:00

abstract：:The early embryo and periconceptional period is a window during which environmental factors may cause permanent change in the pattern and characteristics of development leading to risk of adult onset disease. This has now been demonstrated across small and large animal models and also in the human. Most evidence of pe...

journal_title：Journal of developmental origins of health and disease

authors： Fleming TP,Velazquez MA,Eckert JJ

更新日期：2015-10-01 00:00:00

abstract：:The hypothesis was that maternal intake of the antioxidant alpha-lipoid acid (ALA), during the developmental period of the hypothalamic orexigenic neurons, causes a permanent beneficial effect in offspring metabolism. Pregnant Wistar rats were fed with standard diet (food) + ALA (0.4% wt/wt) from day 14 of gestation t...

journal_title：Journal of developmental origins of health and disease

authors： Rabaglino MB,Moreira-Espinoza MJ,Lagares C,Garay MI,Quiroga P,Pasqualini ME,Francini F,Beltramo D

更新日期：2020-12-11 00:00:00

abstract：:Postnatal and antenatal depression present significant public health concerns. Current opinion on the use of these terms is noted. Previous research findings demonstrate that detrimental effects of untreated maternal depression/anxiety are potentially severe and impact on the whole family; longer-term effects on child...

journal_title：Journal of developmental origins of health and disease

authors： Hall P

更新日期：2012-08-01 00:00:00

abstract：:Childhood obesity rates are higher among Indigenous compared with non-Indigenous Australian children. It has been hypothesized that early-life influences beginning with the intrauterine environment predict the development of obesity in the offspring. The aim of this paper was to assess, in 227 mother-child dyads from ...

journal_title：Journal of developmental origins of health and disease

authors： Pringle KG,Lee YQ,Weatherall L,Keogh L,Diehm C,Roberts CT,Eades S,Brown A,Smith R,Lumbers ER,Brown LJ,Collins CE,Rae KM

更新日期：2019-02-01 00:00:00

abstract：:Low birth weight is associated with increased risk of cardiovascular disease in adulthood. Intrauterine growth restriction (IUGR) hearts have fewer CMs in early postnatal life, which may impair postnatal cardiovascular function and hence, explain increased disease risk, but whether the cardiomyocyte deficit persists t...

journal_title：Journal of developmental origins of health and disease

authors： Vranas S,Heinemann GK,Liu H,De Blasio MJ,Owens JA,Gatford KL,Black MJ

更新日期：2017-10-01 00:00:00

abstract：:Footprints in Time: The Longitudinal Study of Indigenous Children (LSIC) is a national study of 1759 Australian Aboriginal and Torres Strait Islander children living across urban, regional and remote areas of Australia. The study is in its 11th wave of annual data collection, having collected extensive data on topics ...

journal_title：Journal of developmental origins of health and disease

authors： Salmon M,Skelton F,Thurber KA,Bennetts Kneebone L,Gosling J,Lovett R,Walter M

更新日期：2019-02-01 00:00:00

abstract：:Depression and anxiety in the antenatal period are of public health concern given potential adverse effects for both mother and infant. Both are under-researched in the first trimester of pregnancy, especially in Africa. We examine the prevalence of first trimester antenatal depression and anxiety in a cohort of South...

journal_title：Journal of developmental origins of health and disease

authors： Redinger S,Norris SA,Pearson RM,Richter L,Rochat T

更新日期：2018-02-01 00:00:00

abstract：:The objectives of this study were to describe the prevalence of cigarette use and water pipe smoking in Jordanian university students and to analyze differences in determinants between cigarette smokers and non-smokers. A cross-sectional questionnaire was administered to a random sample of 400 students (18-24 years, 5...

journal_title：Journal of developmental origins of health and disease

authors： Farajat M,Hoving C,De Vries H

更新日期：2011-06-01 00:00:00

abstract：:Intrauterine factors important for cognitive development, such as birth weight, chorionicity and umbilical cord characteristics were investigated. A total of 663 twin pairs completed the Wechsler Intelligence Scale for Children-Revised and scores were available for Performance, Verbal and Total Intelligence Quotient (...

journal_title：Journal of developmental origins of health and disease

authors： Antoniou EE,Fowler T,Thiery E,Southwood TR,van Gestel S,Jacobs N,Vlietinck R,van Os J,Rijsdijk FV,Derom C,Zeegers MP

更新日期：2013-12-01 00:00:00