Sex- and afferent-specific differences in histamine receptor expression in vagal afferents of rats: A potential mechanism for sexual dimorphism in prevalence and severity of asthma.

abstract：:The effects of regular exercise versus a single bout of exercise on cognition, anxiety, and mood were systematically examined in healthy, sedentary young adults who were genotyped to determine brain-derived neurotrophic factor (BDNF) allelic status (i.e., Val-Val or Val66Met polymorphism). Participants were evaluated ...

journal_title：Neuroscience

authors： Hopkins ME,Davis FC,Vantieghem MR,Whalen PJ,Bucci DJ

更新日期：2012-07-26 00:00:00

abstract：:Our working hypothesis is that brain neurotrophins and brain Na(+),K(+)-ATPase may be strongly associated with the occurrence of depression in animals subjected to chronic unpredictable mild stress (CUMS). Still, we believe that chrysin, a natural and bioactive flavonoid found in honey and some plants, can provide sat...

journal_title：Neuroscience

authors： Filho CB,Jesse CR,Donato F,Giacomeli R,Del Fabbro L,da Silva Antunes M,de Gomes MG,Goes AT,Boeira SP,Prigol M,Souza LC

更新日期：2015-03-19 00:00:00

abstract：:5-Hydroxytrytamine (serotonin) type 3A receptors (5-HT3ARs), as the only ligand-gated ion channels in the serotonin receptor family, are known to regulate neuronal excitation and release of GABA in hippocampal interneurons. However, their physiological role in glutamatergic synaptic plasticity remains unclear. Here, w...

journal_title：Neuroscience

authors： Yu Y,Cao DQ,Xu HY,Sun M,Huang ZL,Yung WH,Lu N,Huang Y

更新日期：2014-10-10 00:00:00

abstract：:Recent studies investigating neural correlates of human thirst have identified various subcortical and telencephalic brain areas. The experience of thirst represents a homeostatic emotion and a state that slowly evolves over time. Therefore, the present study aims at systematically examining cerebral perfusion during ...

journal_title：Neuroscience

authors： Meier L,Federspiel A,Jann K,Wiest R,Strik W,Dierks T

更新日期：2018-07-15 00:00:00

abstract：:The primary somatosensory cortex (S1) projects to the thalamus and brainstem somatosensory nuclei and modulates somatosensory information ascending to the S1 itself. However, the projections from the S1 to the brainstem second-order somatosensory neuron pools have not been fully studied. To address this in rats, we fi...

journal_title：Neuroscience

authors： Tomita A,Kato T,Sato F,Haque T,Oka A,Yamamoto M,Ono T,Bae YC,Maeda Y,Sessle BJ,Yoshida A

更新日期：2012-01-03 00:00:00

abstract：:Lesioning of thalamic target neurons in the adult rat provokes a resorption of terminal axonal branches of afferent neurons from the dorsal column nuclei. There is, however, no massive neuronal loss in the dorsal column nuclei. In the adult, therefore, the thalamic post synaptic target cells influence primarily the ex...

journal_title：Neuroscience

authors： Marty S,Peschanski M

更新日期：1994-10-01 00:00:00

abstract：:In situ hybridization was used to measure the levels of proenkephalin mRNA and prodynorphin mRNA in regions of rat striatum and nucleus accumbens. Chronic administration of haloperidol (2.4 mg/kg/day for 7 days) increased the levels of proenkephalin mRNA in both striatum and nucleus accumbens. In contrast, the levels ...

journal_title：Neuroscience

authors： Morris BJ,Höllt V,Herz A

更新日期：1988-05-01 00:00:00

abstract：:The incidence of anxiety, mood, substance abuse disorders and schizophrenia increases during adolescence. Epidemiological evidence confirms that exposure to stress during sensitive periods of development can create vulnerabilities that put genetically predisposed individuals at increased risk for psychiatric disorders...

journal_title：Neuroscience

authors： Taylor SB,Taylor AR,Koenig JI

更新日期：2013-09-26 00:00:00

abstract：:Nickel (Ni(2+)) is a toxic metal that affects the function of several ionic channels. In the N-methyl-d-aspartate (NMDA) subtype of glutamate receptor (NR), it causes activity enhancement of the channels containing the NR2B subunit and voltage-independent inhibition of those containing NR2A. Thus, it may represent a f...

journal_title：Neuroscience

authors： Gavazzo P,Tedesco M,Chiappalone M,Zanardi I,Marchetti C

更新日期：2011-03-17 00:00:00

abstract：:The protective effect of diphenyliodonium, known as an inhibitor of flavin enzymes including nitric oxide synthases, was examined against the neurotoxicity of excitatory amino acids on cultured spinal neurons of the rat. Diphenyliodonium reduced the neuronal damage induced by 15-min exposure to glutamate or N-methyl-D...

journal_title：Neuroscience

authors： Nakamura Y,Tsuji K,Shuto M,Ogita K,Yoneda Y,Shimamoto K,Shibata T,Kataoka K

更新日期：1997-01-01 00:00:00

abstract：:Eleven healthy tobacco smoking adult male volunteers of mixed race were tobacco abstinent overnight for this study. In each subject, positron emission tomographic images of regional cerebral metabolism of glucose with [18F]fluorodeoxyglucose were obtained in two conditions in the morning on different days: about 3min ...

journal_title：Neuroscience

authors： Domino EF,Minoshima S,Guthrie SK,Ohl L,Ni L,Koeppe RA,Cross DJ,Zubieta J

更新日期：2000-01-01 00:00:00

abstract：:Autotomy in experimental animals following peripheral nerve section has been interpreted as a sign of pain corresponding to the chronic pain observed in patients with extensive nerve lesions. Such pain may be alleviated by spinal cord stimulation. In the present study, the effect of such stimulation, via chronically i...

journal_title：Neuroscience

authors： Gao XX,Ren B,Linderoth B,Meyerson BA

更新日期：1996-11-01 00:00:00

abstract：:Microtubule-associated protein 1B is a major constituent of the neuronal cytoskeleton during the early stages of development. This protein and its phosphorylated isoform, microtubule-associated protein 1B-P, defined by the monoclonal antibody 1B-P [Boyne L. J. et al. (1995) J. Neurosci. Res. 40, 439-450], are present ...

journal_title：Neuroscience

authors： Ma D,Connors T,Nothias F,Fischer I

更新日期：2000-01-01 00:00:00

abstract：:GABA(B) receptors at the cone terminals in bullfrog retina were characterized by immunocytochemical and whole-cell patch clamp techniques in retinal slice preparations. Somata, axons and synaptic terminals (pedicles) of cones were both GABA(B) receptor (GABA(B)R) 1 and GABA(B)R2 immunoreactive. Physiologically, barium...

journal_title：Neuroscience

authors： Liu J,Zhao JW,Du JL,Yang XL

更新日期：2005-01-01 00:00:00

abstract：:Compelling lines of evidence indicate that overexpression of dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A) in subjects with trisomy 21 (Down syndrome[DS]) contributes to the abnormal structure and function of the DS brain. In the present study, we used a novel, phospho-dependent antibody r...

journal_title：Neuroscience

authors： Kida E,Walus M,Jarząbek K,Palminiello S,Albertini G,Rabe A,Hwang YW,Golabek AA

更新日期：2011-11-10 00:00:00

abstract：:The nucleus accumbens is considered to be critically involved in the control of complex motivated behaviors. By modulating its glutamatergic excitatory input, mesolimbic dopaminergic afferents have been implicated in the reinforcing properties of drugs of abuse. However, they might not represent the only path for infl...

journal_title：Neuroscience

authors： d'Alcantara P,Ledent C,Swillens S,Schiffmann SN

更新日期：2001-01-01 00:00:00

abstract：:Neurotrophin gene expression in adult brain varies according to physiological activity and following brain injury, suggesting a role in neuronal maintenance and plasticity. However, the exact roles and mechanisms of action of neurotrophins in the adult brain are still poorly understood. We have recently demonstrated t...

journal_title：Neuroscience

authors： Guilhem D,Dreyfus PA,Makiura Y,Suzuki F,Onteniente B

更新日期：1996-06-01 00:00:00

abstract：:Inside-out patch recordings from rat acutely dissociated cerebral cortical neurons revealed time and voltage-dependent activity of a large-conductance calcium-activated potassium channel. Channel activity inactivated within minutes following a depolarizing voltage step, and was recovered from inactivation by membrane ...

journal_title：Neuroscience

authors： Smith MA,Ashford ML

更新日期：2000-01-01 00:00:00

abstract：:The objective of this study was to explore changes in hyaluronan levels in the cerebrospinal fluid (CSF) in a spinal cord compression model, to investigate whether hyaluronan tetrasaccharide was involved in this process, and to test the effects of hyaluronan tetrasaccharide on neuron and oligodendrocyte repair. We dev...

journal_title：Neuroscience

authors： Wang J,Rong W,Hu X,Liu X,Jiang L,Ma Y,Dang G,Liu Z,Wei F

更新日期：2012-05-17 00:00:00

abstract：:A diet high in total fat (HF) reduces hippocampal levels of brain-derived neurotrophic factor (BDNF), a crucial modulator of synaptic plasticity, and a predictor of learning efficacy. We have evaluated the capacity of voluntary exercise to interact with the effects of diet at the molecular level. Animal groups were ex...

journal_title：Neuroscience

authors： Molteni R,Wu A,Vaynman S,Ying Z,Barnard RJ,Gómez-Pinilla F

更新日期：2004-01-01 00:00:00

abstract：:Long non-coding RNA MALAT1 was previously revealed to express abnormally in animal and cellular models of stroke, suggesting its indispensable role in stroke. The aims of the present study were to further investigate the functions of MALAT1 and to elucidate the underlying molecular mechanisms. Oxygen glucose deprivati...

journal_title：Neuroscience

authors： Gao C,Zhang CC,Yang HX,Hao YN

更新日期：2020-05-21 00:00:00

abstract：:Hippocampal neurogenesis in adult mammals is influenced by many factors. Lesioning of the entorhinal cortex is a standard model used to study injury and repair in the hippocampus. Here we use bromodeoxyuridine (BrdU) labeling combined with immunohistochemical identification using cell type specific markers to follow t...

journal_title：Neuroscience

authors： Gama Sosa MA,Wen PH,De Gasperi R,Perez GM,Senturk E,Friedrich VL Jr,Elder GA

更新日期：2004-01-01 00:00:00

abstract：:The enzyme choline-O-acetyltransferase catalyses the biosynthesis of acetylcholine from acetyl coenzyme A and choline and is considered as one of the best markers for cholinergic nerve endings. The distribution of this enzymatic activity was analysed during the purification of plasma membranes of purely cholinergic ne...

journal_title：Neuroscience

authors： Eder-Colli L,Amato S

更新日期：1985-06-01 00:00:00

abstract：:Among vertebrates hippocampus forms the major component of the brain in consolidating information from short-term memory to long-term memory. Aging is considered as the major risk factor for memory impairment in sporadic Alzheimer's disease (SAD) like pathology. Present study thus aims at investigating whether age-spe...

journal_title：Neuroscience

authors： Moorthi P,Premkumar P,Priyanka R,Jayachandran KS,Anusuyadevi M

更新日期：2015-08-20 00:00:00

abstract：:The accessory olfactory bulb of the mouse was studied by current source-density analysis of field potentials to determine the laminar and temporal distribution of synaptic currents evoked by electrical stimulation of the vomeronasal organ. The one-dimensional current source-density analysis revealed two major spatiall...

journal_title：Neuroscience

authors： Kaba H,Keverne EB

更新日期：1992-07-01 00:00:00

abstract：:The central mechanism of fever induction is triggered by an action of prostaglandin E(2) (PGE(2)) on neurons in the preoptic area (POA) through the EP3 subtype of prostaglandin E receptor. EP3 receptor (EP3R)-expressing POA neurons project directly to the dorsomedial hypothalamus (DMH) and to the rostral raphe pallidu...

journal_title：Neuroscience

authors： Nakamura Y,Nakamura K,Morrison SF

更新日期：2009-06-30 00:00:00

abstract：:Linear sweep voltammograms recorded with carbon paste electrodes in the striatum of the unanaesthetised, unrestrained rat show three separate peaks. The effect on peak 3 of either unilateral 6-hydroxydopamine lesion of the substantia nigra or intraperitoneal administration of alpha-methyl-paratyrosine, supports our ea...

journal_title：Neuroscience

authors： O'Neill RD,Fillenz M

更新日期：1985-03-01 00:00:00

abstract：:Inter-limb reflexes play an important role in coordinating behaviors involving different limbs. Previous studies have demonstrated that human elbow muscles express an inter-limb stretch reflex at long-latency (50-100 ms), a timing consistent with a trans-cortical linkage. Here we probe for inter-limb stretch reflexes ...

journal_title：Neuroscience

authors： Muraoka T,Kurtzer I

更新日期：2020-04-01 00:00:00

abstract：:Increasing evidence indicates that both the ATP P2X receptors and adrenergic systems play a very important role in the development of nociception. However, there is little information concerning the interactions between these two systems in the dorsal root ganglia (DRG). In the present study, we examined the effects o...

journal_title：Neuroscience

authors： Tan Y,Sun L,Zhang Q

更新日期：2011-03-10 00:00:00

abstract：:Microdialysis was combined with a highly sensitive sequential multiple antigen radioimmunoassay to simultaneously measure extracellular cholecystokinin and neurotensin fragments from discrete regions of the rat brain in vivo. The assay was conducted in 96-well plates and provided a limit of detection for both peptides...

journal_title：Neuroscience

authors： Maidment NT,Siddall BJ,Rudolph VR,Erdelyi E,Evans CJ

更新日期：1991-01-01 00:00:00