Abstract:
BACKGROUND:Sufficient clinical data are not available on the effect of hypothyroidism on olfactory function in adults. In this study, we aimed to evaluate the olfactory function of adult patients diagnosed with primary hypothyroidism. METHODS:Forty-five patients aged between 18 and 60 years who were diagnosed with clinical primary hypothyroidism and 45 healthy controls who had normal thyroid function tests were included in the study. Sniffin' Sticks olfactory test results of the 2 groups were compared. The relationships between thyroid function tests and olfactory parameters were evaluated. RESULTS:Odor threshold, identification, and discrimination scores of the hypothyroid group were significantly lower than those of the control group (p < 0.001). A significant positive correlation was detected between free triiodothyronine (FT3) levels and odor threshold, identification, and discrimination scores (p < 0.001). There was no significant relationship between thyroid-stimulating hormone (TSH) or free thyroxine (FT4) levels and olfactory parameters. CONCLUSION:Our study revealed diminished olfactory function in adults with hypothyroidism. FT3 levels were found to have a more significant relationship with olfactory parameters than TSH or FT4 levels.
journal_name
Int Forum Allergy Rhinoljournal_title
International forum of allergy & rhinologyauthors
Günbey E,Karlı R,Gökosmanoğlu F,Düzgün B,Ayhan E,Atmaca H,Ünal Rdoi
10.1002/alr.21565subject
Has Abstractpub_date
2015-10-01 00:00:00pages
919-22issue
10eissn
2042-6976issn
2042-6984journal_volume
5pub_type
杂志文章abstract:BACKGROUND:Previous studies have reviewed the safety of preparing and administering allergy injection immunotherapy in a physician's office, and showed no evidence of infectious complications. The current study examines the antimicrobial properties of the common additives used in preparation of multidose immunotherapy ...
journal_title:International forum of allergy & rhinology
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pub_type: 临床试验,杂志文章,多中心研究
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pub_type: 杂志文章,评审
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