Human papillomavirus infection and biomarkers in sinonasal inverted papillomas: clinical significance and molecular mechanisms.

abstract：BACKGROUND:The management of chronic rhinosinusitis with nasal polyposis (CRSwNP) becomes unclear when patients require multiple courses of corticosteroids to maintain quality of life. Repeated courses of corticosteroids carry increased risks to patients. Although endoscopic sinus surgery (ESS) is an effective therapeu...

journal_title：International forum of allergy & rhinology

authors： Leung RM,Dinnie K,Smith TL

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Over 45 million Americans suffer from recurrent headaches, and an estimated $11.9 million was spent on doctor's visits for rhinogenic pain last year. Sphenopalatine blocks have been described for various facial pain syndromes, but their use and the type of blockade agents remain controversial. The objective ...

journal_title：International forum of allergy & rhinology

authors： Rodman R,Dutton J

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:The most dramatic complication in endonasal surgery is inadvertent injury to the internal carotid artery (ICA) with massive bleeding. Nasal packing is the favored technique for control; however, this often causes complete carotid occlusion or carotid stenosis, contributing to the morbidity and mortality of t...

journal_title：International forum of allergy & rhinology

authors： Valentine R,Boase S,Jervis-Bardy J,Dones Cabral JD,Robinson S,Wormald PJ

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) has been defined as inflammation of the paranasal sinuses lasting at least 12 weeks with corresponding 2 or more "cardinal symptoms" that include: (1) nasal obstruction; (2) thick nasal discharge; (3) facial pain/pressure; and (4) reduction or loss of sense of smell. Although pri...

journal_title：International forum of allergy & rhinology

authors： DeConde AS,Mace JC,Alt JA,Soler ZM,Orlandi RR,Smith TL

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Early postoperative care following endoscopic sinus surgery (ESS) has been suggested to minimize avoidable complications and optimize long-term outcomes. Several postoperative care strategies have been proposed but a formal comprehensive evaluation of the evidence has never been performed. The purpose of thi...

journal_title：International forum of allergy & rhinology

authors： Rudmik L,Soler ZM,Orlandi RR,Stewart MG,Bhattacharyya N,Kennedy DW,Smith TL

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:The aim of this study was to demonstrate how direct electrical stimulation can activate the olfactory bulb after denervation of the olfactory nerve input. METHODS:Sprague-Dawley rats (n = 5) were anesthetized and olfactory bulbs exposed. Olfactory nerves were transected by passing a Teflon blade between the...

journal_title：International forum of allergy & rhinology

authors： Coelho DH,Socolovsky LD,Costanzo RM

更新日期：2018-05-02 00:00:00

abstract：BACKGROUND:Interleukin (IL)-33 plays an important role in controlling immune responses in barrier tissues, and is a potent mediator of inflammatory diseases such as asthma, rheumatoid disease, and chronic rhinosinusitis. The aims of the present study were 2-fold: (1) to determine the stimulatory effect of tumor necrosi...

journal_title：International forum of allergy & rhinology

authors： Park IH,Park JH,Shin JM,Lee HM

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Povidone-iodine (PVP-I) is well known as an antiseptic and exhibits extensive activity against various pathogens. However, due to its uniquely unpleasant nature, it cannot be used locally to deactivate various sinonasal pathogens. Therefore, we developed a PVP-I composite that blocks the unpleasant odor of P...

journal_title：International forum of allergy & rhinology

authors： Jeronimo LP,Choi MR,Yeon SH,Park SK,Yoon YH,Choi SH,Kim HJ,Jang IT,Park JK,Rha KS,Kim YM

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis with nasal polyps (CRSwNP) is prolonged inflammation of the sinonasal mucosa. Interleukin-32 (IL-32) is involved in the pathogenesis of chronic lung inflammatory diseases. The aim of study is to compare the expression level of IL-32 in normal nasal mucosa and CRSwNP and to investigate ...

journal_title：International forum of allergy & rhinology

authors： Cho JS,Kim JA,Park JH,Park IH,Han IH,Lee HM

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Earlier studies have suggested that patients with chronic rhinosinusitis (CRS) report worse sleep quality than population norms. What remains unknown is whether these patients are actually experiencing measurable changes in objective sleep parameters. The goal of this study was to prospectively evaluate obje...

journal_title：International forum of allergy & rhinology

authors： Alt JA,Ramakrishnan VR,Platt MP,Schlosser RJ,Storck T,Soler ZM

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:This study reviews the published literature related to extramedullary sinonasal plasmacytomas. Clinical presentation, demographics, treatment, and outcomes of this uncommon disease are reported. METHODS:A systematic review of studies for sinonasal plasmacytomas from 1950 to 2012 was conducted. A PubMed data...

journal_title：International forum of allergy & rhinology

authors： D'Aguillo C,Soni RS,Gordhan C,Liu JK,Baredes S,Eloy JA

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Debate still persists on the relation between olfactory bulb volume (OBV) and olfactory function. Many studies suggest that olfactory deprivation decreases the OBV. The aim of this study was to compare the olfactory threshold and OBV of patients with nasal polyps to healthy individuals and to evaluate the im...

journal_title：International forum of allergy & rhinology

authors： Sadeghi M,Amali A,Ezabadi SR,Motiee-Langroudi M,Farshchi S,Mokhtari Z

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Patient compliance is critical for successful allergen immunotherapy (AIT). Previous studies suggest that AIT compliance is worse outside of controlled clinical trials, with reported subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT) noncompliance at 11% to 50% and 3% to 25%, respectively....

journal_title：International forum of allergy & rhinology

authors： Leader BA,Rotella M,Stillman L,DelGaudio JM,Patel ZM,Wise SK

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:There is a lack of population-based, multi-institutional analyses of factors associated with morbidity and mortality following pituitary tumor excision. METHODS:The American College of Surgeons National Surgical Quality Improvement Project files were used to compile information on patients that had undergon...

journal_title：International forum of allergy & rhinology

authors： Lawrence LA,Baker AB,Nguyen SA,Karnezis TT,Soler ZM,Schlosser RJ

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:The immunologic mechanisms driving inflammation in the upper airways of patients with chronic rhinosinusitis (CRS) are poorly understood. Previous studies have shown that B cells and immunoglobulin E (IgE) levels are elevated in the nasal tissue of patients with atopic chronic rhinosinusitis without nasal po...

journal_title：International forum of allergy & rhinology

authors： Rashan AR,Goshn E,Peterson A,Yang Y,Phillips M,Sahaf B,Herzenberg L,Nayak JV

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:We recently demonstrated the bitter taste receptor T2R38 upregulates sinonasal mucosal innate defense in response to gram-negative quorum-sensing molecules through increased nitric oxide production and mucociliary clearance. T2R38 was initially identified in the quest to understand the variability in bitter ...

journal_title：International forum of allergy & rhinology

authors： Adappa ND,Howland TJ,Palmer JN,Kennedy DW,Doghramji L,Lysenko A,Reed DR,Lee RJ,Cohen NA

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:The objective of this work was to evaluate prevalence of eosinophilic esophagitis (EoE) in the United States, and analyze prevalence of atopic disease in patients with EoE. The study design was a retrospective administrative database analysis in U.S.-based outpatient settings. METHODS:A retrospective claims...

journal_title：International forum of allergy & rhinology

authors： Benninger MS,Strohl M,Holy CE,Hanick AL,Bryson PC

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:The pathogenic roles of fungus and bacteria in chronic rhinosinusitis (CRS) remain unclear. Recently, we described the bacterial ball, which is distinct from the fungus ball, as an unusual phenotype of bacterial infection. In this study, we investigated the clinical, histopathologic, and immunologic characte...

journal_title：International forum of allergy & rhinology

authors： Kim DK,Wi YC,Shin SJ,Kim KR,Kim DW,Cho SH

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:The lateral nasal wall (LNW) flap provides vascularized endonasal reconstruction primarily in revision surgery. Although the harvesting technique and reconstructive surface have been reported, the arterial supply to the LNW flap and its clinical implications is not well defined. This study presents anatomica...

journal_title：International forum of allergy & rhinology

authors： Lavigne P,Vega MB,Ahmed OH,Gardner PA,Snyderman CH,Wang EW

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Lumbar drain (LD) use in the management of cerebrospinal fluid (CSF) rhinorrhea remains controversial. We analyzed the relationship between LD placement and CSF leak recurrence after endoscopic repair. METHODS:A retrospective case series was conducted. Patients who underwent CSF leak repair from 1999 to 201...

journal_title：International forum of allergy & rhinology

authors： Caballero N,Bhalla V,Stankiewicz JA,Welch KC

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Antibiotics are commonly used in the management of both acute rhinosinusitis and acute exacerbations of chronic rhinosinusitis. With their common use, they have become the leading medication for litigation. It is crucial for the provider to be familiar with potential complications and the medico-legal ramifi...

journal_title：International forum of allergy & rhinology

authors： Poetker DM,Smith TL

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Bronchial asthma is one of the most common chronic diseases in childhood, with a current prevalence of 6% to 9%, but a prevalence that is increasing at an alarming rate. Asthma is a complex genetic disorder with strong environmental influence. It imposes a growing burden on our society in terms of morbidity,...

journal_title：International forum of allergy & rhinology

authors： Toskala E,Kennedy DW

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Trefoil factor family (TFF) peptides are mucin-associated secretory products that are produced in the airways and gastrointestinal tract. These peptides appear to play an important role in mucosal healing and epithelial protection and are overexpressed in chronically inflamed gastrointestinal tissues. We hyp...

journal_title：International forum of allergy & rhinology

authors： Li P,Turner JH

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Oncocytomas and oncocytic carcinomas are rare tumors of the sinonasal cavity with the propensity for local invasion. This report and systematic review details a case of a nasal oncocytoma involving the lacrimal sac and provides an update of the current literature. METHODS:A systematic literature review was ...

journal_title：International forum of allergy & rhinology

authors： Hodzic Z,Rowan NR,Kashiwazaki R,Willson TJ,Wang EW,Lee SE

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:Anatomic limitations complicate complete eradication of debris from the maxillary sinus using an exclusively transnasal (TN) endoscopic technique. Creation of a canine fossa trephination (CFT) permits a more direct approach than removal via the maxillary ostium. METHODS:Microdebrider eradication of debris co...

journal_title：International forum of allergy & rhinology

authors： Feldt BA,McMains KC,Weitzel EK

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Insufficiency of the nasal valve is increasingly being recognized as a cause of nasal airway obstruction. The condition is associated with many symptoms, including nasal congestion, sleep disturbance, snoring, and an overall decline in quality of life (QoL). An in-office, minimally invasive radiofrequency tr...

journal_title：International forum of allergy & rhinology

authors： Ephrat M,Jacobowitz O,Driver M

更新日期：2020-08-09 00:00:00

abstract：BACKGROUND:According to epidemiologic studies, fine particulate matter (particulate matter ≤2.5 μm, PM2.5) is closely associated with increases in the incidence and severity of chronic rhinosinusitis (CRS). However, the role of PM2.5 in the pathophysiology of CRS remains largely unknown. In this study, we investigated ...

journal_title：International forum of allergy & rhinology

authors： Zhao R,Guo Z,Dong W,Deng C,Han Z,Liu J,Wang H,Zhuang G,Zhang R

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Allergic rhinitis (AR) is a chronic systemic allergic disease with an association reported between allergy and anxiety. The objective of the current study was therefore to investigate and retrospectively evaluate the factors that may possibly induce state and trait anxiety among patients with AR and vasomoto...

journal_title：International forum of allergy & rhinology

authors： Xi L,Cao F,Zhang Y,Zhang L

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:The available allergic rhinitis (AR) literature continues to grow. Critical evaluation and understanding of this literature is important to appropriately utilize this knowledge in the care of AR patients. The International Consensus statement on Allergy and Rhinology: Allergic Rhinitis (ICAR:AR) has been pro...

journal_title：International forum of allergy & rhinology

authors： Wise SK,Lin SY,Toskala E

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Spontaneous cerebrospinal fluid (CSF) rhinorrhea has been associated with elevated intracranial pressure (ICP). As such, ICP reducing measures are commonly employed to optimize repair. Although postoperative acetazolamide use has been described, no data currently exists on the potential for preoperative use....

journal_title：International forum of allergy & rhinology

authors： Tilak AM,Koehn H,Mattos J,Payne SC

更新日期：2019-03-01 00:00:00