Immunotherapy compliance: comparison of subcutaneous versus sublingual immunotherapy.

abstract：BACKGROUND:Environmental factors such as inhaled pollutants like cigarette smoke may play a significant role in diseases of the upper airway including chronic rhinosinusitis (CRS). The objectives of this review are to summarize prior studies that describe the correlation between active smoking and secondhand smoke (SHS...

journal_title：International forum of allergy & rhinology

authors： Reh DD,Higgins TS,Smith TL

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Many asthmatic patients have coexisting allergic rhinitis (AR). This study aims to investigate the compliance of physicians with respiratory medicine specialty (PRMs) to Global Initiative for Asthma (GINA) and Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines during the management of their asthma-...

journal_title：International forum of allergy & rhinology

authors： Su N,Lin J,Liu G,Yin K,Zhou X,Shen H,Chen P,Chen R,Liu C,Wu C,Zhao J,Lin Y

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:After endoscopic sinus surgery (ESS), endoscopy is used to gauge surgical success and clinical outcomes. Prior studies have not examined this topic prospectively using validated outcome metrics across multiple institutions. METHODS:A multi-institutional, prospective study of patients with chronic rhinosinus...

journal_title：International forum of allergy & rhinology

authors： Schlosser RJ,Storck K,Smith TL,Mace JC,Rudmik L,Shahangian A,Soler ZM

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:We have previously demonstrated that persistent symptoms following functional endoscopic sinus surgery for chronic rhinosinusitis (CRS) is associated with Gram-negative bacterial carriage. Mechanisms for this remain unknown. We wished to determine whether Gram-negative carriage in patients with CRS with nasa...

journal_title：International forum of allergy & rhinology

authors： Tabet P,Endam LM,Boisvert P,Boulet LP,Desrosiers M

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:The etiology of the intense inflammatory response showed by patients with allergic fungal rhinosinusitis (AFRS) remains a mystery. Potential sources of this inflammation may include fungal proteases. Protease-activated receptors (PARs) are components of the innate immune response that are modulated by proteo...

journal_title：International forum of allergy & rhinology

authors： Ebert CS Jr,McKinney KA,Urrutia G,Wu M,Rose AS,Fleischman GM,Thorp B,Senior BA,Zanation AM

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:As part of this primer, this article is intended to introduce new and emerging therapies for treating asthma. METHODS:A PubMed search was performed for the years 2013 through 2015 for asthma review, asthma treatment, asthma therapy, and asthma new. Subset searches were additionally performed as suggested by...

journal_title：International forum of allergy & rhinology

authors： Calhoun KH

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Early postoperative care following endoscopic sinus surgery (ESS) has been suggested to minimize avoidable complications and optimize long-term outcomes. Several postoperative care strategies have been proposed but a formal comprehensive evaluation of the evidence has never been performed. The purpose of thi...

journal_title：International forum of allergy & rhinology

authors： Rudmik L,Soler ZM,Orlandi RR,Stewart MG,Bhattacharyya N,Kennedy DW,Smith TL

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Previous studies have consistently shown that females with chronic rhinosinusitis (CRS) have a greater CRS symptom burden than males with CRS. Our objective was to determine whether differential disease perception could explain this phenomenon. METHODS:A total of 500 participants (239 males, 261 females) wi...

journal_title：International forum of allergy & rhinology

authors： Phillips KM,Bergmark RW,Hoehle LP,Shu ET,Caradonna DS,Gray ST,Sedaghat AR

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Patients with eosinophilic chronic rhinosinusitis (ECRS) have been shown to have greater disease severity and poorer treatment outcomes after sinus surgery. Although the inflammatory pattern of ECRS is essential to diagnosing this subtype, there is currently no consensus for diagnosis. Our aim in this study ...

journal_title：International forum of allergy & rhinology

authors： McHugh T,Snidvongs K,Xie M,Banglawala S,Sommer D

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Earlier studies have suggested that patients with chronic rhinosinusitis (CRS) report worse sleep quality than population norms. What remains unknown is whether these patients are actually experiencing measurable changes in objective sleep parameters. The goal of this study was to prospectively evaluate obje...

journal_title：International forum of allergy & rhinology

authors： Alt JA,Ramakrishnan VR,Platt MP,Schlosser RJ,Storck T,Soler ZM

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:This study reviews the published literature related to extramedullary sinonasal plasmacytomas. Clinical presentation, demographics, treatment, and outcomes of this uncommon disease are reported. METHODS:A systematic review of studies for sinonasal plasmacytomas from 1950 to 2012 was conducted. A PubMed data...

journal_title：International forum of allergy & rhinology

authors： D'Aguillo C,Soni RS,Gordhan C,Liu JK,Baredes S,Eloy JA

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) has been defined as inflammation of the paranasal sinuses lasting at least 12 weeks with corresponding 2 or more "cardinal symptoms" that include: (1) nasal obstruction; (2) thick nasal discharge; (3) facial pain/pressure; and (4) reduction or loss of sense of smell. Although pri...

journal_title：International forum of allergy & rhinology

authors： DeConde AS,Mace JC,Alt JA,Soler ZM,Orlandi RR,Smith TL

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Patients  with  viral respiratory infections/viral rhinitis/common colds are often treated with antibiotic; however, there is little information on whether or how bacterial microbiota in the nose and nasopharynx might influence the course of viral illnesses. METHODS:To initiate investigation of possible int...

journal_title：International forum of allergy & rhinology

authors： Allen EK,Pitkäranta A,Mäki M,Hendley JO,Laakso S,Sale MM,Winther B

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:The role of bacteria in the etiopathogenesis of chronic rhinosinusitis (CRS) remains an area of interest. The impact of surgery and factors such as the presence of polyps, asthma, and aspirin sensitivity on the bacterial state are poorly understood. To determine the effect of these factors, this study examin...

journal_title：International forum of allergy & rhinology

authors： Cleland EJ,Bassiouni A,Wormald PJ

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:We recently demonstrated the bitter taste receptor T2R38 upregulates sinonasal mucosal innate defense in response to gram-negative quorum-sensing molecules through increased nitric oxide production and mucociliary clearance. T2R38 was initially identified in the quest to understand the variability in bitter ...

journal_title：International forum of allergy & rhinology

authors： Adappa ND,Howland TJ,Palmer JN,Kennedy DW,Doghramji L,Lysenko A,Reed DR,Lee RJ,Cohen NA

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Nasal polyposis is characterized by persistent inflammation but the pathogenesis is complex and still debatable. Autophagy has been associated with many human health problems including chronic inflammatory airway diseases. Whether autophagy plays a role in nasal polyps and could be a therapeutic target is co...

journal_title：International forum of allergy & rhinology

authors： Chen JY,Hour TC,Yang SF,Chien CY,Chen HR,Tsai KL,Ko JY,Wang LF

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Arterial epistaxis is commonly seen in the rhinology clinic and can have a significant impact on quality of life. Previous studies have explored various therapies to address epistaxis. METHODS:Patients were treated in the outpatient clinic or operating room by microwave ablation (MWA) with a 2450-MHz cooled...

journal_title：International forum of allergy & rhinology

authors： Lou ZC,Dong Y,Lou ZH

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:The objective of this study was to evaluate the impact of bilateral inferior turbinate reduction (BITR) on patient-reported quality of life (QOL) following endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS). METHODS:This was a prospective cohort study. Patients with CRS, who were recruited from...

journal_title：International forum of allergy & rhinology

authors： Scangas GA,Bleier BS,Husain Q,Holbrook EH,Gray ST,Metson R

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Interleukin 13 (IL-13) is a pleiotropic cytokine that has been shown to be important in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) and other type 2 inflammation-related diseases. Increased IL-13 expression can elicit several pro-inflammatory effects, including eosinophilia, and pat...

journal_title：International forum of allergy & rhinology

authors： Khalil SM,Bernstein I,Kulaga H,Gour N,Rowan N,Lajoie S,Lane AP

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:The lateral nasal wall (LNW) flap provides vascularized endonasal reconstruction primarily in revision surgery. Although the harvesting technique and reconstructive surface have been reported, the arterial supply to the LNW flap and its clinical implications is not well defined. This study presents anatomica...

journal_title：International forum of allergy & rhinology

authors： Lavigne P,Vega MB,Ahmed OH,Gardner PA,Snyderman CH,Wang EW

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Bronchial asthma is one of the most common chronic diseases in childhood, with a current prevalence of 6% to 9%, but a prevalence that is increasing at an alarming rate. Asthma is a complex genetic disorder with strong environmental influence. It imposes a growing burden on our society in terms of morbidity,...

journal_title：International forum of allergy & rhinology

authors： Toskala E,Kennedy DW

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:The pathophysiologic mechanism of allergy is dependent on the action of many redox-sensitive proinflammatory mediators. However, even though redox disturbances are believed to be a hallmark of inflammation, little is known of the effect of redox imbalance to the pathophysiology of allergic rhinitis. We thus ...

journal_title：International forum of allergy & rhinology

authors： Guibas GV,Spandou E,Meditskou S,Vyzantiadis TA,Priftis KN,Anogianakis G

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:The association between sinonasal microbiome and clinical outcomes of patients with chronic rhinosinusitis (CRS) is unclear. We performed a systematic review of prior studies evaluating the CRS microbiome in relation to clinical outcomes. METHODS:Computerized searches of PubMed/Medline, Cochrane, and EMBASE...

journal_title：International forum of allergy & rhinology

authors： Wang JC,Moore CA,Epperson MV,Sedaghat AR

更新日期：2020-04-01 00:00:00

abstract：:Early reports have suggested that smell loss may be an early symptom associated with the pandemic known as coronavirus disease 2019 (COVID-19). The possibility that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might cause olfactory dysfunction is certainly plausible. Patients presenting to specialized ...

journal_title：International forum of allergy & rhinology

authors： Soler ZM,Patel ZM,Turner JH,Holbrook EH

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:The objective of the evidence base review was to systematically evaluate the literature to elucidate the potential role of oral antifungal therapy in management of chronic rhinosinusitis (CRS) and its subtypes. METHODS:Articles for inclusion were identified by query of appropriate search terms in the PubMed...

journal_title：International forum of allergy & rhinology

authors： Thanasumpun T,Batra PS

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:The ciprofloxacin-coated sinus stent (CSS) has unique therapeutic potential to deliver antibiotics to the sinuses. The objective of this study is to evaluate the efficacy of the CSS stent in eliminating Pseudomonas aeruginosa infection in a rabbit model of sinusitis. METHODS:A ciprofloxacin-eluting sinus st...

journal_title：International forum of allergy & rhinology

authors： Cho DY,Lim DJ,Mackey C,Skinner D,Weeks C,Gill GS,Hergenrother RW,Swords WE,Woodworth BA

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:The role of bacteria in the pathogenesis of chronic rhinosinusitis (CRS) remains uncertain. Recent evidence suggests that bacteria are able to establish microcolonies within the underlying mucosa. However, to date there has been no systematic comparison of bacterial community composition and diversity in the...

journal_title：International forum of allergy & rhinology

authors： Kim RJ,Biswas K,Hoggard M,Taylor MW,Douglas RG

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:The endoscopic modified Lothrop procedure (EMLP) is commonly performed in recalcitrant frontal sinusitis, in part to achieve better penetration of medicated irrigations postoperatively. Although EMLP requires a septectomy for exposure, it is unknown whether septectomy size affects delivery of irrigations. In...

journal_title：International forum of allergy & rhinology

authors： Roxbury CR,Tang D,Shah J,McBride J,Woodard TD,Sindwani R

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:The Draf III procedure is an effective endoscopic approach to the treatment of frontal sinus disorders, but has a significant restenosis rate. The objective of the current study is to assess long-term success of the Draf III mucosal grafting technique. METHODS:Patients undergoing Draf III with mucosal graft...

journal_title：International forum of allergy & rhinology

authors： Illing EA,Cho do Y,Riley KO,Woodworth BA

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Allergic rhinitis (AR) is a chronic systemic allergic disease with an association reported between allergy and anxiety. The objective of the current study was therefore to investigate and retrospectively evaluate the factors that may possibly induce state and trait anxiety among patients with AR and vasomoto...

journal_title：International forum of allergy & rhinology

authors： Xi L,Cao F,Zhang Y,Zhang L

更新日期：2016-11-01 00:00:00