What rhinologists and allergists should know about the medico-legal implications of antibiotic use: a review of the literature.

abstract：BACKGROUND:Surgical management of the superior turbinate (ST) is required to access the sella in endoscopic endonasal transsphenoidal surgery (EETS) for pituitary adenoma. Two common ST management techniques include partial resection of the ST (PRST) and intentional lateralization of the ST (ILST). Given the concentrat...

journal_title：International forum of allergy & rhinology

authors： Li P,Luo K,Zhang Q,Wang Z

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Olfactory inflammation in chronic rhinosinusitis (CRS) is associated with cytokines that may result in the death of olfactory sensory neurons. The principal signaling molecules involved in the apoptotic pathway are c-Jun N-terminal kinases (JNK). Although the JNK pathway has emerged as a key player in progra...

journal_title：International forum of allergy & rhinology

authors： Victores AJ,Chen M,Smith A,Lane AP

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:The role of human papillomavirus (HPV) in sinonasal inverted papillomas (IPs) is controversial. Determining the prevalence of HPV infection and its impact on the molecular biology of these tumors is critical to characterizing its role in the pathogenesis of IPs. METHODS:A total of 112 paraffin-embedded IPs ...

journal_title：International forum of allergy & rhinology

authors： Scheel A,Lin GC,McHugh JB,Komarck CM,Walline HM,Prince ME,Zacharek MA,Carey TE

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Allergic rhinitis (AR) is a complex chronic inflammatory disease of the nasal mucosa, caused by an interaction between genetic and environmental factors. As evidence suggests that some genetic variants may increase susceptibility to both AR and asthma, the objective of this study was to identify asthma susce...

journal_title：International forum of allergy & rhinology

authors： Zhao Y,Zhang Y,Zhang L

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Chronic rhinosinusitis (CRS) is a common condition encountered in primary care medicine and is estimated to affect 12.5% of the United States population. This study aims to compare methods of assessing health utility in CRS. METHODS:A cross-sectional sample of CRS patients (n = 137) were interviewed using d...

journal_title：International forum of allergy & rhinology

authors： Ference EH,Stubbs V,Lidder AK,Chandra RK,Conley D,Avila PC,Hirsch AG,Min JY,Smith SS,Kern RC,Tan BK

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:The objective of this case series was to report what is to the best of our knowledge the first reports of nasopharyngeal and soft palate pseudomeningoceles tracking submucosally from the sphenoid sinus. METHODS:Analysis of cases through medical records. RESULTS:Two cases of middle-aged male patients presen...

journal_title：International forum of allergy & rhinology

authors： Lieberman SM,Ojo RB,Casiano RR

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Nasal polyposis is characterized by persistent inflammation and remodeling in sinonasal mucosa. Toll-like receptor 9 (TLR9) is a DNA receptor of the innate immune system that plays a pivotal role in fibrosis and inflammatory responses. The aim of this study is to explore the expression, activity, and potenti...

journal_title：International forum of allergy & rhinology

authors： Park SK,Jin SY,Yeon SH,Lee SB,Xu J,Yoon YH,Rha KS,Kim YM

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:The role of bacteria in the pathogenesis of chronic rhinosinusitis (CRS) remains uncertain. Recent evidence suggests that bacteria are able to establish microcolonies within the underlying mucosa. However, to date there has been no systematic comparison of bacterial community composition and diversity in the...

journal_title：International forum of allergy & rhinology

authors： Kim RJ,Biswas K,Hoggard M,Taylor MW,Douglas RG

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:It has been found that the most common adverse reaction which occurs more frequently on cetirizine than on placebo is somnolence. However, the somnolence rate varied widely among different studies. The objective of this study was to assess the somnolence effect of cetirizine 10 mg daily compared to placebo i...

journal_title：International forum of allergy & rhinology

authors： Du Q,Zhou Y

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Patients with chronic rhinosinusitis (CRS) exhibit centrally mediated behavioral changes commonly referred to as "sickness behavior." Sleep alteration is a component of sickness behavior which is estimated to affect up to 70 million patients annually. Patients with CRS have poor sleep quality, and little is ...

journal_title：International forum of allergy & rhinology

authors： Alt JA,Smith TL

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:The endoscopic modified Lothrop procedure (EMLP) is used to manage ongoing refractory frontal sinusitis after failed previous endoscopic sinus surgery (ESS), but this approach has a significant restenosis rate. We evaluated the potential benefits of mucosal grafts and pedicled flaps on the opening of the new...

journal_title：International forum of allergy & rhinology

authors： Wang YP,Shen PH,Hsieh LC,Wormald PJ

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Oral steroids are commonly used in the management of chronic rhinosinusitis (CRS) with and without nasal polyps (CRSwNP and CRSsNP, respectively). Past reports have included evaluation of the evidence for the use of oral steroids in CRS subtypes. However, a review with evidence-based recommendations for all ...

journal_title：International forum of allergy & rhinology

authors： Poetker DM,Jakubowski LA,Lal D,Hwang PH,Wright ED,Smith TL

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Early postoperative care following endoscopic sinus surgery (ESS) has been suggested to minimize avoidable complications and optimize long-term outcomes. Several postoperative care strategies have been proposed but a formal comprehensive evaluation of the evidence has never been performed. The purpose of thi...

journal_title：International forum of allergy & rhinology

authors： Rudmik L,Soler ZM,Orlandi RR,Stewart MG,Bhattacharyya N,Kennedy DW,Smith TL

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Sufficient clinical data are not available on the effect of hypothyroidism on olfactory function in adults. In this study, we aimed to evaluate the olfactory function of adult patients diagnosed with primary hypothyroidism. METHODS:Forty-five patients aged between 18 and 60 years who were diagnosed with cli...

journal_title：International forum of allergy & rhinology

authors： Günbey E,Karlı R,Gökosmanoğlu F,Düzgün B,Ayhan E,Atmaca H,Ünal R

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Chronic sinusitis is universal in cystic fibrosis (CF) and our current treatments are ineffective in reversing sinus disease. The objective of this work was to determine if increasing CF transmembrane conductance regulator (CFTR) activity by ivacaftor could treat CF sinus disease and assess its effect on pri...

journal_title：International forum of allergy & rhinology

authors： Chang EH,Tang XX,Shah VS,Launspach JL,Ernst SE,Hilkin B,Karp PH,Abou Alaiwa MH,Graham SM,Hornick DB,Welsh MJ,Stoltz DA,Zabner J

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:The mechanism of airway remodeling in chronic rhinosinusitis with nasal polyposis (CRSwNP) remains unknown. We wished to determine whether profibrotic transforming growth factor beta 1 (TGF-β1) and activin A and their downstream signaling proteins are increased in CRSwNP and if they are regulated in epitheli...

journal_title：International forum of allergy & rhinology

authors： Yamin M,Holbrook EH,Gray ST,Busaba NY,Lovett B,Hamilos DL

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:According to epidemiologic studies, fine particulate matter (particulate matter ≤2.5 μm, PM2.5) is closely associated with increases in the incidence and severity of chronic rhinosinusitis (CRS). However, the role of PM2.5 in the pathophysiology of CRS remains largely unknown. In this study, we investigated ...

journal_title：International forum of allergy & rhinology

authors： Zhao R,Guo Z,Dong W,Deng C,Han Z,Liu J,Wang H,Zhuang G,Zhang R

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Nonallergic rhinitis (NAR) is currently a diagnosis of exclusion with an unclear pathophysiologic mechanism and limited treatment options. In patients diagnosed with NAR based on symptoms, negative skin testing and positive optical rhinometry (ORM), the study's objective was to evaluate the therapeutic actio...

journal_title：International forum of allergy & rhinology

authors： Zebda D,Jiang ZY,Gibson MM,Pham C,Ahmadi S,Floren S,Yao WC,Citardi MJ,Luong AU

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Our objectives were to evaluate collaboration with medical students and other nondoctoral authors, and assess whether mentoring such students influences the academic productivity of senior authors. METHODS:Six issues of the Laryngoscope and International Forum of Allergy & Rhinology (IFAR) were examined for...

journal_title：International forum of allergy & rhinology

authors： Svider PF,Husain Q,Mauro KM,Folbe AJ,Baredes S,Eloy JA

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Endoscopic repair of anterior skull-base defects has become the gold standard for management of cerebrospinal fluid (CSF) rhinorrhea. Both improved techniques and adjuvant therapies have led to accepted success rates of greater than 90%. As management has evolved, shorter hospitalizations have been required ...

journal_title：International forum of allergy & rhinology

authors： Adams AS,Francis DO,Russell PT

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:The pathogenic roles of fungus and bacteria in chronic rhinosinusitis (CRS) remain unclear. Recently, we described the bacterial ball, which is distinct from the fungus ball, as an unusual phenotype of bacterial infection. In this study, we investigated the clinical, histopathologic, and immunologic characte...

journal_title：International forum of allergy & rhinology

authors： Kim DK,Wi YC,Shin SJ,Kim KR,Kim DW,Cho SH

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Povidone-iodine (PVP-I) is well known as an antiseptic and exhibits extensive activity against various pathogens. However, due to its uniquely unpleasant nature, it cannot be used locally to deactivate various sinonasal pathogens. Therefore, we developed a PVP-I composite that blocks the unpleasant odor of P...

journal_title：International forum of allergy & rhinology

authors： Jeronimo LP,Choi MR,Yeon SH,Park SK,Yoon YH,Choi SH,Kim HJ,Jang IT,Park JK,Rha KS,Kim YM

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Nitric oxide (NO) is released in the airway as a critical component of innate immune defense against invading pathogenic organisms. It is well documented that bacteriostatic and bactericidal effects of NO are concentration-dependent. However, few data exist comparing relative susceptibility of common pathoge...

journal_title：International forum of allergy & rhinology

authors： Workman AD,Carey RM,Kohanski MA,Kennedy DW,Palmer JN,Adappa ND,Cohen NA

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Previous studies have consistently shown that females with chronic rhinosinusitis (CRS) have a greater CRS symptom burden than males with CRS. Our objective was to determine whether differential disease perception could explain this phenomenon. METHODS:A total of 500 participants (239 males, 261 females) wi...

journal_title：International forum of allergy & rhinology

authors： Phillips KM,Bergmark RW,Hoehle LP,Shu ET,Caradonna DS,Gray ST,Sedaghat AR

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:The purpose of this work was to perform a systematic review regarding ossifying fibroma and its multiple variants of the paranasal sinuses, and to identify any clinical differences between the multiple variants. METHODS:A search of the U.S. National Library of Medicine (PubMed) database was performed for th...

journal_title：International forum of allergy & rhinology

authors： Manes RP,Ryan MW,Batra PS,Mendelsohn D,Fang YV,Marple BF

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Trefoil factor family (TFF) peptides are mucin-associated secretory products that are produced in the airways and gastrointestinal tract. These peptides appear to play an important role in mucosal healing and epithelial protection and are overexpressed in chronically inflamed gastrointestinal tissues. We hyp...

journal_title：International forum of allergy & rhinology

authors： Li P,Turner JH

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Variants of squamous cell carcinoma (SCC) make up 15% of all cases of SCC of the upper aerodigestive tract. There are 5 main histologic variants of SCC in the head and neck region: verrucous (VSCC), papillary (PSCC), spindle cell (sarcomatoid) (SCSC), basaloid (BSCC), and adenosquamous (ASC). Conventional si...

journal_title：International forum of allergy & rhinology

authors： Vazquez A,Khan MN,Blake DM,Patel TD,Baredes S,Eloy JA

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Reported revision rates for endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS) vary significantly. Several investigations examining revision rates for ESS have been limited by duration of follow-up, academic centers, or small surgeon cohorts. The objective of this study was to define the long-te...

journal_title：International forum of allergy & rhinology

authors： Smith KA,Orlandi RR,Oakley G,Meeks H,Curtin K,Alt JA

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:The Draf III procedure is an effective endoscopic approach to the treatment of frontal sinus disorders, but has a significant restenosis rate. The objective of the current study is to assess long-term success of the Draf III mucosal grafting technique. METHODS:Patients undergoing Draf III with mucosal graft...

journal_title：International forum of allergy & rhinology

authors： Illing EA,Cho do Y,Riley KO,Woodworth BA

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Social determinants of health can have a substantial impact on treatment outcomes. Prior study has shown that socioeconomic status influences the likelihood of improvement in quality-of-life (QOL) following endoscopic sinus surgery (ESS). However, the impact of socioeconomic factors on changes in productivit...

journal_title：International forum of allergy & rhinology

authors： Beswick DM,Mace JC,Soler ZM,Rudmik L,Alt JA,Smith KA,Detwiller KY,Ramakrishnan VR,Smith TL

更新日期：2019-09-01 00:00:00