Low Lymphatic Pumping Pressure in the Legs Is Associated with Leg Edema and Lower Quality of Life in Healthy Volunteers.

abstract：BACKGROUND:Secondary lymphedema, resulting from damage to lymphatic vessels, is a common sequela following surgical removal of lymph nodes for cancer. Current therapeutics for treating lymphedema are limited and further research on underlying causes is warranted. Published studies on molecular mechanisms of lymphedema ...

journal_title：Lymphatic research and biology

authors： Wang S,Nie D,Rubin JP,Kokai L

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Lymphedema may affect patients' health-related quality of life (HRQoL) and thus a disease-specific questionnaire is needed. The Lymphedema Quality of life Inventory (LyQLI) has been tested for reliability and validity. The purpose of this study was to test the LyQLI for responsiveness and sensitivity. METHO...

journal_title：Lymphatic research and biology

authors： Klernäs P,Johnsson A,Boyages J,Brorson H,Munnoch A,Johansson K

更新日期：2018-06-01 00:00:00

abstract：: Introduction: Mass drug administration and morbidity management and disability prevention (MMDP) though considered as two pillars of global program for elimination of filariasis, implementation of MMDP was disregarded in several endemic countries. Limb hygiene is the main ...

journal_title：Lymphatic research and biology

authors： De Britto L,Kamaraj P,Vijayalakshmi G,Das LK,Krishnakumari A,Anbusivam S,Supriya VK,Yuvaraj J

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Lymphatic stomata are small lymphatic openings in the serosal membrane that communicate with the serosal cavity. Although these stomata have primarily been studied in experimental mammals, little is known concerning the presence and properties of lymphatic stomata in the adult human pleura. Thus, adult human...

journal_title：Lymphatic research and biology

authors： Oshiro H,Miura M,Iobe H,Kudo T,Shimazu Y,Aoba T,Okudela K,Nagahama K,Sakamaki K,Yoshida M,Nagao T,Nakaya T,Kurata A,Ohtani O

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:It has recently become apparent that the lymph pump is an electrical entity that rivals the heart in complexity. Many interesting currents have been demonstrated by voltage clamping isolated lymphatic smooth muscle cells, but until now the role of these currents in the intact syncitium has not been studied. ...

journal_title：Lymphatic research and biology

authors： Beckett EA,Hollywood MA,Thornbury KD,McHale NG

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Studies of lymphatic function often employ collecting lymphatic vessels that exhibit large-amplitude, spontaneous contractions. Data from such preparations have been analyzed using cardiac pump analogies that require accurate determination of vascular dimensions, including external (OD) and internal (ID) dia...

journal_title：Lymphatic research and biology

authors： Davis MJ,Zawieja DC,Gashev AA

更新日期：2006-04-01 00:00:00

abstract：: Background: Surgical excision and/or radiation targeting of regional lymph nodes are an essential component in the clinical management of cancer. Importantly, a more accurate understanding of lymphatic anatomy could enable refinement of present treatment strategies. Given ...

journal_title：Lymphatic research and biology

authors： Fournier DE,Groh AMR,Nair SM,Norley CJD,Pollmann SI,Holdsworth DW,Power NE,Beveridge TS

更新日期：2020-04-01 00:00:00

abstract：: Background: The aims of this study were to explore, using visual art methodology, how children and adolescents perceive their lymphedema and conceptualize the barriers and enablers in self-management and to explore the role of an educational camp in promoting self-efficacy...

journal_title：Lymphatic research and biology

authors： Moffatt C,Aubeeluck A,Stasi E,Mestre S,Rowan S,Murray S,Quere I

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:In arm lymphedema secondary to axillary surgery and radiotherapy (breast cancer-related lymphedema), the swelling is largely epifascial and lymph flow per unit epifascial volume is impaired. The subfascial muscle compartment is not measurably swollen despite the iatrogenic damage to its axillary drainage pat...

journal_title：Lymphatic research and biology

authors： Stanton AW,Mellor RH,Cook GJ,Svensson WE,Peters AM,Levick JR,Mortimer PS

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Lymphedema is the abnormal accumulation of protein-rich fluid in the interstitial space. Primary lymphedema is a rare genetic condition with both autosomal dominant and autosomal recessive modes of inheritance. Three genes, FLT4 (VEGFR3), FOXC2, and SOX18 cause varying forms of primary lymphedema. In industr...

journal_title：Lymphatic research and biology

authors： Finegold DN,Schacht V,Kimak MA,Lawrence EC,Foeldi E,Karlsson JM,Baty CJ,Ferrell RE

更新日期：2008-01-01 00:00:00

abstract：: Background: Platelet-rich plasma (PRP) is an autologous concentrated preparation of platelets characterized by lymphangiogenetic and tissue-repairing effects. Although PRP has been safely used in many different fields, there is no clinical study regarding the use of PRP in...

journal_title：Lymphatic research and biology

authors： Akgul A,Tarakci E,Arman N,Civi T,Irmak S

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Lower limb lymphedema (LLL) is a common complication of cancer treatment. The disease is chronic and progressive with no cure. Although a common and significant source of morbidity, the impact of this condition on health-related quality of life (HRQOL) has only recently been addressed. In effort to identify ...

journal_title：Lymphatic research and biology

authors： Cemal Y,Jewell S,Albornoz CR,Pusic A,Mehrara BJ

更新日期：2013-03-01 00:00:00

abstract：: Background: The purpose of this study was to investigate acute cardiovascular responses to manual lymphatic drainage (MLD) on different parts of the body. Materials and Methods: Thirty healthy individuals (10 women and 20 men) ...

journal_title：Lymphatic research and biology

authors： Esmer M,Keser I,Erer D,Kupeli B

更新日期：2019-06-01 00:00:00

abstract：PURPOSE:Lymphedema can have a negative impact on the function and quality of life (QOL) of patients, but most studies have examined lymphedema as a binary variable, rather than a multidimensional disease that ranges in severity. This study explored the potential impact of lymphedema severity on function and overall QOL...

journal_title：Lymphatic research and biology

authors： Lee TS,Morris CM,Czerniec SA,Mangion AJ

更新日期：2018-02-01 00:00:00

abstract：:Lymphatic filariasis characterized by the dysfunction of the lymphatics can lead to severe (and often) irreversible lymphedema and elephantiasis. Decades of research in the field shows that the establishment of the adult parasites in the lymphatics triggers a cascade of events that ultimately results in tissue scarrin...

journal_title：Lymphatic research and biology

authors： Bennuru S,Nutman TB

更新日期：2009-12-01 00:00:00

abstract：:The knowledge of humoral and cellular factors retained in tissues affected by ineffective lymph transport is necessary to comprehend the pathological mechanisms of the evolving changes in the extremity. In this article, we report our observations on changes in the protein composition of lymph in obstructive lymphedema...

journal_title：Lymphatic research and biology

authors： Olszewski WL

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:We performed experiments to test whether isolated lymphatic vessels would remain viable after overnight long-distance shipment. METHODS AND RESULTS:Freshly isolated segments of rat mesenteric lymphatic vessels were placed into tubes filled by chilled D-MEM/F12 supplemented with antibiotics and shipped via o...

journal_title：Lymphatic research and biology

authors： Gashev AA,Davis MJ

更新日期：2010-12-01 00:00:00

abstract：:Exciting studies involving the molecular regulation of lymphangiogenesis in lymphatic-associated disorders (e.g., wound healing, lymphedema and tumor metastasis) have focused renewed attention on the intrinsic relationship between lymphatic endothelial cells (LECs) and extracellular matrix (ECM) microenvironment. ECM ...

journal_title：Lymphatic research and biology

authors： Ji RC

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:The aim of this prospective controlled study was to assess the efficacy of two different combination treatment modalities of lymphedema (LE). Manual lymphatic drainage (MLD) and compression bandage combination (complex decongestive therapy) have been compared with intermittent pneumatic compression (IPC) plu...

journal_title：Lymphatic research and biology

authors： Gurdal SO,Kostanoglu A,Cavdar I,Ozbas A,Cabioglu N,Ozcinar B,Igci A,Muslumanoglu M,Ozmen V

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Primary idiopathic lymphedema is an uncommon condition that typically affects the lower extremities. Patients have a malformed lymphatic system that causes subcutaneous fluid and adipose deposition. Rarely, the disease also has been described in the upper extremities. The purpose of this study was to investi...

journal_title：Lymphatic research and biology

authors： Goss JA,Maclellan RA,Greene AK

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Near-infrared fluorescence (NIRF) imaging is a new imaging technique that is used to visualize lymphatic vessels in humans. It has a high spatial and temporal resolution, allowing real-time visualization of lymphatic flow. METHODS AND RESULTS:The current study investigated the intra- and inter-individual va...

journal_title：Lymphatic research and biology

authors： Groenlund JH,Telinius N,Skov SN,Hjortdal V

更新日期：2017-09-01 00:00:00

abstract：: Background: Local tissue water in patients with breast cancer-related lymphedema (BCRL) can be assessed by measurement of the tissue dielectric constant using the MoistureMeterD Compact® (MMDC) device, or by performing the pitting test. Although these assessment methods ar...

journal_title：Lymphatic research and biology

authors： De Vrieze T,Gebruers N,Nevelsteen I,De Groef A,Tjalma WAA,Thomis S,Dams L,Van der Gucht E,Penen F,Devoogdt N

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:The purpose of this study is to investigate the effects of the aqua-lymphatic therapy (ALT) on unilateral lower extremity lymphedema in the maintenance phase. MATERIALS AND METHODS:This is a randomized controlled trial with a blinded assessor. The study was completed with 30 ALT and 27 control group partici...

journal_title：Lymphatic research and biology

authors： Ergin G,Karadibak D,Sener HO,Gurpinar B

更新日期：2017-09-01 00:00:00

abstract：:Abstracts Background: Arm lymphedema after breast cancer surgery affects women both from physical and psychological points of view. Lymphedema leads to adipose tissue deposition. Liposuction and controlled compression therapy (CCT) reduces the lymphedema completely. METHODS AND RESULTS:Sixty female patients with arm ...

journal_title：Lymphatic research and biology

authors： Hoffner M,Bagheri S,Hansson E,Manjer J,Troëng T,Brorson H

更新日期：2017-03-01 00:00:00

abstract：: Background: Bioimpedance spectroscopy detects unilateral lymphedema if the ratio of extracellular fluid (ECF) between arms or between legs is outside three standard deviations (SDs) of the normative mean. Detection of bilateral lymphedema, common after bilateral breast or ...

journal_title：Lymphatic research and biology

authors： Steele ML,Janda M,Vagenas D,Ward LC,Cornish BH,Box R,Gordon S,Matthews M,Poppitt SD,Plank LD,Yip W,Rowan A,Reul-Hirche H,Obermair A,Hayes SC

更新日期：2018-12-01 00:00:00

abstract：:The present report describes a case with the triad of yellow nail syndrome (YNS) and the use of low-pressure compression pump as treatment of lymphedema in YNS. A 71-year-old woman presented with bilateral lower extremity lymphedema, yellow nails, and recurrent bilateral pleural effusion. In this case, we specifically...

journal_title：Lymphatic research and biology

authors： Polat AK,Dang HT,Soran A

更新日期：2012-03-01 00:00:00

abstract：: Background: Multiple staging systems for classifying the severity of lymphedema exist. The International Society of Lymphology (ISL) stage is considered standard for clinical reporting, but the relationship between clinical and functional/imaging stage remains poorly defin...

journal_title：Lymphatic research and biology

authors： Garza RM,Ooi ASH,Falk J,Chang DW

更新日期：2019-06-01 00:00:00

abstract：:Primary lymphedema is due to abnormal congenital development or dysfunction in the lymphatic system. Limited data exist on the prevalence of primary lymphedema and there are only few studies focusing on primary lymphedema. The purpose of this article is to review the current options for surgical treatment of primary l...

journal_title：Lymphatic research and biology

authors： Lee JH,Chang DW

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Bioimpedance spectroscopy (BIS) is commonly used in the assessment and monitoring of lymphedema. This study investigated electrodes as a source of variability that could impact the accuracy of BIS in the clinic and determined if Ag/AgCl electrocardiograph (ECG) electrodes could be used as an alternative to i...

journal_title：Lymphatic research and biology

authors： Svensson BJ,Dylke ES,Ward LC,Kilbreath SL

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Analysis of the innervation pattern of the thoracic duct in young and elderly human subjects has been performed. The subdivision of the vessels in cervical and lumbar region were taken in consideration. METHODS AND RESULTS:Immunostaining for general nerve fibers with a PGP 9.5 marker disclosed a diffuse inn...

journal_title：Lymphatic research and biology

authors： Mignini F,Sabbatini M,Cavallotti C,Cavallotti C

更新日期：2012-06-01 00:00:00