Primary Lymphedema of the Upper Extremities: Clinical and Lymphoscintigraphic Features in 23 Patients.

abstract：PURPOSE:Lymphedema can have a negative impact on the function and quality of life (QOL) of patients, but most studies have examined lymphedema as a binary variable, rather than a multidimensional disease that ranges in severity. This study explored the potential impact of lymphedema severity on function and overall QOL...

journal_title：Lymphatic research and biology

authors： Lee TS,Morris CM,Czerniec SA,Mangion AJ

更新日期：2018-02-01 00:00:00

abstract：: Background: The use of bioimpedance spectroscopy (BIS) for the detection of unilateral upper limb lymphedema is growing. Currently, normatively determined diagnostic thresholds using bioimpedance are available for females only. It is unclear if they are suitable for males ...

journal_title：Lymphatic research and biology

authors： Xie AZT,Lee MJ,Dylke E

更新日期：2020-02-01 00:00:00

abstract：:Lymphatic filariasis characterized by the dysfunction of the lymphatics can lead to severe (and often) irreversible lymphedema and elephantiasis. Decades of research in the field shows that the establishment of the adult parasites in the lymphatics triggers a cascade of events that ultimately results in tissue scarrin...

journal_title：Lymphatic research and biology

authors： Bennuru S,Nutman TB

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Lymphedema of limbs affects a large mass of tissues. Pathological changes develop in skin and subcutaneous tissue. Bacterial retention in edema fluid is followed by chronic inflammatory reaction. The question arises whether the chronic processes affecting a large mass of limb tissues are reflected in the ser...

journal_title：Lymphatic research and biology

authors： Zaleska MT,Olszewski WL

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Studies of lymphatic function often employ collecting lymphatic vessels that exhibit large-amplitude, spontaneous contractions. Data from such preparations have been analyzed using cardiac pump analogies that require accurate determination of vascular dimensions, including external (OD) and internal (ID) dia...

journal_title：Lymphatic research and biology

authors： Davis MJ,Zawieja DC,Gashev AA

更新日期：2006-04-01 00:00:00

abstract：: Background: Mesenteric lymph (ML) has been implicated in the development of multiple organ dysfunction syndrome in critical illness. Extracellular RNAs play a role in cell-to-cell communication during physiological and disease processes but they are rarely studied in ML. W...

journal_title：Lymphatic research and biology

authors： Hong J,Blenkiron C,Tsai P,Premkumar R,Nachkebia S,Tun SM,Petzer A,Windsor JA,Hickey AJ,Phillips AR

更新日期：2019-10-01 00:00:00

abstract：:Despite the fact that the central nervous system parenchyma does not contain lymphatics, extracranial lymphatic vessels play a very important role in volumetric cerebrospinal fluid (CSF) transport. The most important extracranial location at which lymphatics gain access to CSF is in the nasal submucosa after CSF conve...

journal_title：Lymphatic research and biology

authors： Johnston M

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Compared to volume/circumference measurements to diagnose lymphedema, thickening and disturbance of echogenicity of cutis and subcutis associated with the development of lymphedema is measured directly by ultrasonography. The aim of the present study was to investigate the evolution of thickness and echogeni...

journal_title：Lymphatic research and biology

authors： Devoogdt N,Pans S,De Groef A,Geraerts I,Christiaens MR,Neven P,Vergote I,Van Kampen M

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Lymphedema may affect patients' health-related quality of life (HRQoL) and thus a disease-specific questionnaire is needed. The Lymphedema Quality of life Inventory (LyQLI) has been tested for reliability and validity. The purpose of this study was to test the LyQLI for responsiveness and sensitivity. METHO...

journal_title：Lymphatic research and biology

authors： Klernäs P,Johnsson A,Boyages J,Brorson H,Munnoch A,Johansson K

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Lymphatic stomata are small lymphatic openings in the serosal membrane that communicate with the serosal cavity. Although these stomata have primarily been studied in experimental mammals, little is known concerning the presence and properties of lymphatic stomata in the adult human pleura. Thus, adult human...

journal_title：Lymphatic research and biology

authors： Oshiro H,Miura M,Iobe H,Kudo T,Shimazu Y,Aoba T,Okudela K,Nagahama K,Sakamaki K,Yoshida M,Nagao T,Nakaya T,Kurata A,Ohtani O

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Near-infrared fluorescence (NIRF) imaging is a new imaging technique that is used to visualize lymphatic vessels in humans. It has a high spatial and temporal resolution, allowing real-time visualization of lymphatic flow. METHODS AND RESULTS:The current study investigated the intra- and inter-individual va...

journal_title：Lymphatic research and biology

authors： Groenlund JH,Telinius N,Skov SN,Hjortdal V

更新日期：2017-09-01 00:00:00

abstract：: Background: Lymphedema is a disorder in which lymph accumulates in the interstitial spaces due to poor lymphatic flow resulting from hypoplasia or aplasia of the lymphatic vessels, or to morpho-functional alterations that impair lymphatic flow. Lymphedema is a debilitating...

journal_title：Lymphatic research and biology

authors： Baglivo M,Martelli F,Paolacci S,Manara E,Michelini S,Bertelli M

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Lymphedema leads to adipose tissue deposition. Water-fat magnetic resonance imaging (MRI) can quantify and localize fat and water. The presence of excess fat and excess water/muscle in the subfascial compartment of the lymphedematous limb has not been investigated before. The aim of this study was to investi...

journal_title：Lymphatic research and biology

authors： Hoffner M,Peterson P,Månsson S,Brorson H

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:Secondary lymphedema, resulting from damage to lymphatic vessels, is a common sequela following surgical removal of lymph nodes for cancer. Current therapeutics for treating lymphedema are limited and further research on underlying causes is warranted. Published studies on molecular mechanisms of lymphedema ...

journal_title：Lymphatic research and biology

authors： Wang S,Nie D,Rubin JP,Kokai L

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Surgical manipulations of the axilla may cause a condition known as Axillary Web Syndrome (AWS). The systems compromised and the sequence of events leading to this syndrome remains unknown. This study evaluated clinical, surgical, and vascular factors associated with onset and duration of AWS after breast ca...

journal_title：Lymphatic research and biology

authors： Furlan C,Matheus CN,Jales RM,Derchain S,Sarian LO

更新日期：2018-06-01 00:00:00

abstract：:The knowledge of humoral and cellular factors retained in tissues affected by ineffective lymph transport is necessary to comprehend the pathological mechanisms of the evolving changes in the extremity. In this article, we report our observations on changes in the protein composition of lymph in obstructive lymphedema...

journal_title：Lymphatic research and biology

authors： Olszewski WL

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Lymph is pumped through the collecting lymphatic vessels by both intrinsic and extrinsic forces, propelling it downstream back into circulation. The intrinsic lymph pump relies on the spontaneous contraction of lymphatic muscles to generate the force of pumping lymph (P(lp)). However, the association between...

journal_title：Lymphatic research and biology

authors： Saito T,Unno N,Yamamoto N,Inuzuka K,Tanaka H,Sano M,Sugisawa R,Katahashi K,Konno H

更新日期：2015-06-01 00:00:00

abstract：: Background: The Lymphedema Functioning, Disability, and Health questionnaire for Upper Limb Lymphedema (Lymph-ICF-UL) is a health-related quality-of-life questionnaire for patients with breast cancer-related lymphedema. Previous testing of this questionnaire showed very go...

journal_title：Lymphatic research and biology

authors： De Vrieze T,Gebruers N,Nevelsteen I,Tjalma WAA,Thomis S,De Groef A,Dams L,Devoogdt N

更新日期：2020-08-01 00:00:00

abstract：: Background: The aims of this study were to explore, using visual art methodology, how children and adolescents perceive their lymphedema and conceptualize the barriers and enablers in self-management and to explore the role of an educational camp in promoting self-efficacy...

journal_title：Lymphatic research and biology

authors： Moffatt C,Aubeeluck A,Stasi E,Mestre S,Rowan S,Murray S,Quere I

更新日期：2019-04-01 00:00:00

abstract：: Background: Lymphedema may impact patients' health-related quality of life (HRQoL). The purpose of this study was to evaluate HRQoL after two different treatments to the 12-month follow-up point. Methods and Results: Study part...

journal_title：Lymphatic research and biology

authors： Klernäs P,Johnsson A,Boyages J,Brorson H,Munnoch A,Johansson K

更新日期：2020-08-01 00:00:00

abstract：: Background: Conservative nonsurgical treatment has traditionally been applied to lymphedema. Early surgical procedures were invasive and disfiguring and their long-term success was often limited. In contrast, contemporary surgical techniques are much less invasive and have...

journal_title：Lymphatic research and biology

authors： Fernández Peñuela R,Casaní Arazo L,Masiá Ayala J

更新日期：2019-08-01 00:00:00

abstract：: Introduction: Mass drug administration and morbidity management and disability prevention (MMDP) though considered as two pillars of global program for elimination of filariasis, implementation of MMDP was disregarded in several endemic countries. Limb hygiene is the main ...

journal_title：Lymphatic research and biology

authors： De Britto L,Kamaraj P,Vijayalakshmi G,Das LK,Krishnakumari A,Anbusivam S,Supriya VK,Yuvaraj J

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:This study sought to evaluate the effect of elastic compression, functional compressive bandaging, and kinesiotherapy on blood flow of the upper limb with lymphedema secondary to the treatment of breast cancer. METHODS:This was a randomized blind crossover clinical trial with a washout period of 7 days betwe...

journal_title：Lymphatic research and biology

authors： Rezende MS,Marsengo AL,de Jesus Guirro RR,de Oliveira Guirro EC

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Previous studies suggest that rhythmic compression of the abdomen (abdominal lymphatic pump techniques, LPT) enhances immunity and resistance to infectious disease, but direct evidence of this has not been documented. In this study, the thoracic duct of eight anesthetized mongrel dogs was catheterized, so th...

journal_title：Lymphatic research and biology

authors： Hodge LM,King HH,Williams AG Jr,Reder SJ,Belavadi T,Simecka JW,Stoll ST,Downey HF

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Tissue dielectric constant (TDC) and spot bioimpedance measurement (BIA) have a role in the assessment of tissue composition changes in breast cancer-related lymphedema (BCRL). Our aims were to determine whether TDC and spot BIA measures could detect inter-limb differences in BCRL, explore the relationship b...

journal_title：Lymphatic research and biology

authors： Czerniec SA,Ward LC,Kilbreath SL

更新日期：2015-03-01 00:00:00

abstract：:The vasculature of the central nervous system (CNS) is highly specialized with a blood-brain-barrier, reciprocal neuroepithelial-endothelial cell interactions and extensive pericyte coverage. Developmentally, numerous important signaling pathways participate in CNS angiogenesis to orchestrate the precise timing and sp...

journal_title：Lymphatic research and biology

authors： Mancuso MR,Kuhnert F,Kuo CJ

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The composition of breast cancer-related lymphedema (BCRL) has been shown to evolve from the initial accumulation of fluid to the development of fibrotic lesions and abnormal fat deposition. Therefore, precise and reliable assessments of BCRL are required to develop accurate staging and management. Although ...

journal_title：Lymphatic research and biology

authors： Newman AL,Rosenthall L,Towers A,Hodgson P,Shay CA,Tidhar D,Vigano A,Kilgour RD

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Lymph flow depends on both the rate of lymph production by tissues and the extent of passive and active pumping. Here we aim to characterize the passive mechanical properties of a lymphangion in both mid-lymphangion and valve segments to assess regional differences along a lymphangion, as well as evaluating ...

journal_title：Lymphatic research and biology

authors： Rahbar E,Weimer J,Gibbs H,Yeh AT,Bertram CD,Davis MJ,Hill MA,Zawieja DC,Moore JE Jr

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:It has recently become apparent that the lymph pump is an electrical entity that rivals the heart in complexity. Many interesting currents have been demonstrated by voltage clamping isolated lymphatic smooth muscle cells, but until now the role of these currents in the intact syncitium has not been studied. ...

journal_title：Lymphatic research and biology

authors： Beckett EA,Hollywood MA,Thornbury KD,McHale NG

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Lymphedema is the abnormal accumulation of protein-rich fluid in the interstitial space. Primary lymphedema is a rare genetic condition with both autosomal dominant and autosomal recessive modes of inheritance. Three genes, FLT4 (VEGFR3), FOXC2, and SOX18 cause varying forms of primary lymphedema. In industr...

journal_title：Lymphatic research and biology

authors： Finegold DN,Schacht V,Kimak MA,Lawrence EC,Foeldi E,Karlsson JM,Baty CJ,Ferrell RE

更新日期：2008-01-01 00:00:00