Lymphatic Endothelial Cells under Mechanical Stress: Altered Expression of Inflammatory Cytokines and Fibrosis.

abstract：BACKGROUND:We performed experiments to test whether isolated lymphatic vessels would remain viable after overnight long-distance shipment. METHODS AND RESULTS:Freshly isolated segments of rat mesenteric lymphatic vessels were placed into tubes filled by chilled D-MEM/F12 supplemented with antibiotics and shipped via o...

journal_title：Lymphatic research and biology

authors： Gashev AA,Davis MJ

更新日期：2010-12-01 00:00:00

abstract：:Exciting studies involving the molecular regulation of lymphangiogenesis in lymphatic-associated disorders (e.g., wound healing, lymphedema and tumor metastasis) have focused renewed attention on the intrinsic relationship between lymphatic endothelial cells (LECs) and extracellular matrix (ECM) microenvironment. ECM ...

journal_title：Lymphatic research and biology

authors： Ji RC

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:This study sought to evaluate the effect of elastic compression, functional compressive bandaging, and kinesiotherapy on blood flow of the upper limb with lymphedema secondary to the treatment of breast cancer. METHODS:This was a randomized blind crossover clinical trial with a washout period of 7 days betwe...

journal_title：Lymphatic research and biology

authors： Rezende MS,Marsengo AL,de Jesus Guirro RR,de Oliveira Guirro EC

更新日期：2017-03-01 00:00:00

abstract：: Background: Platelet-rich plasma (PRP) is an autologous concentrated preparation of platelets characterized by lymphangiogenetic and tissue-repairing effects. Although PRP has been safely used in many different fields, there is no clinical study regarding the use of PRP in...

journal_title：Lymphatic research and biology

authors： Akgul A,Tarakci E,Arman N,Civi T,Irmak S

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:The spleen has an important physiological role in maintaining blood volume; this study aimed to determine whether during pathophysiological circumstances, namely endotoxemia, the extrasplenic pathway is dysfunctional. We hypothesize that increased 'leakiness' of lymphatics in response to lipopolysaccharide (...

journal_title：Lymphatic research and biology

authors： Brookes ZL,Mansart A,McGown CC,Ross JJ,Reilly CS,Brown NJ

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:A relative inability to capture a sufficiently large patient population in any one geographic location has traditionally limited research into rare diseases. METHODS AND RESULTS:Clinicians interested in the rare disease lymphangioleiomyomatosis (LAM) have worked with the LAM Treatment Alliance, the MIT Medi...

journal_title：Lymphatic research and biology

authors： Nurok M,Eslick I,Carvalho CR,Costabel U,D'Armiento J,Glanville AR,Harari S,Henske EP,Inoue Y,Johnson SR,Lacronique J,Lazor R,Moss J,Ruoss SJ,Ryu JH,Seyama K,Watz H,Xu KF,Hohmann EL,Moss F

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Lymphedema may affect patients' health-related quality of life (HRQoL) and thus a disease-specific questionnaire is needed. The Lymphedema Quality of life Inventory (LyQLI) has been tested for reliability and validity. The purpose of this study was to test the LyQLI for responsiveness and sensitivity. METHO...

journal_title：Lymphatic research and biology

authors： Klernäs P,Johnsson A,Boyages J,Brorson H,Munnoch A,Johansson K

更新日期：2018-06-01 00:00:00

abstract：:Despite the fact that the central nervous system parenchyma does not contain lymphatics, extracranial lymphatic vessels play a very important role in volumetric cerebrospinal fluid (CSF) transport. The most important extracranial location at which lymphatics gain access to CSF is in the nasal submucosa after CSF conve...

journal_title：Lymphatic research and biology

authors： Johnston M

更新日期：2003-01-01 00:00:00

abstract：: Background: The Lymphedema Functioning, Disability, and Health questionnaire for Upper Limb Lymphedema (Lymph-ICF-UL) is a health-related quality-of-life questionnaire for patients with breast cancer-related lymphedema. Previous testing of this questionnaire showed very go...

journal_title：Lymphatic research and biology

authors： De Vrieze T,Gebruers N,Nevelsteen I,Tjalma WAA,Thomis S,De Groef A,Dams L,Devoogdt N

更新日期：2020-08-01 00:00:00

abstract：:Hemangiomas of infancy are very common tumors, but they are heterogeneous in their behavior. A small, but significant, subset causes medical complications or permanent disfigurement, but due to their heterogeneity, there is no appropriate "one size fits all" approach to management. In addition, the rapid evolution of ...

journal_title：Lymphatic research and biology

authors： Frieden IJ

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:The composition of breast cancer-related lymphedema (BCRL) has been shown to evolve from the initial accumulation of fluid to the development of fibrotic lesions and abnormal fat deposition. Therefore, precise and reliable assessments of BCRL are required to develop accurate staging and management. Although ...

journal_title：Lymphatic research and biology

authors： Newman AL,Rosenthall L,Towers A,Hodgson P,Shay CA,Tidhar D,Vigano A,Kilgour RD

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Lymphatic stomata are small lymphatic openings in the serosal membrane that communicate with the serosal cavity. Although these stomata have primarily been studied in experimental mammals, little is known concerning the presence and properties of lymphatic stomata in the adult human pleura. Thus, adult human...

journal_title：Lymphatic research and biology

authors： Oshiro H,Miura M,Iobe H,Kudo T,Shimazu Y,Aoba T,Okudela K,Nagahama K,Sakamaki K,Yoshida M,Nagao T,Nakaya T,Kurata A,Ohtani O

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The aim of this prospective controlled study was to assess the efficacy of two different combination treatment modalities of lymphedema (LE). Manual lymphatic drainage (MLD) and compression bandage combination (complex decongestive therapy) have been compared with intermittent pneumatic compression (IPC) plu...

journal_title：Lymphatic research and biology

authors： Gurdal SO,Kostanoglu A,Cavdar I,Ozbas A,Cabioglu N,Ozcinar B,Igci A,Muslumanoglu M,Ozmen V

更新日期：2012-09-01 00:00:00

abstract：: Background: Lymphedema may impact patients' health-related quality of life (HRQoL). The purpose of this study was to evaluate HRQoL after two different treatments to the 12-month follow-up point. Methods and Results: Study part...

journal_title：Lymphatic research and biology

authors： Klernäs P,Johnsson A,Boyages J,Brorson H,Munnoch A,Johansson K

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:In arm lymphedema secondary to axillary surgery and radiotherapy (breast cancer-related lymphedema), the swelling is largely epifascial and lymph flow per unit epifascial volume is impaired. The subfascial muscle compartment is not measurably swollen despite the iatrogenic damage to its axillary drainage pat...

journal_title：Lymphatic research and biology

authors： Stanton AW,Mellor RH,Cook GJ,Svensson WE,Peters AM,Levick JR,Mortimer PS

更新日期：2003-01-01 00:00:00

abstract：: Background: Mesenteric lymph (ML) has been implicated in the development of multiple organ dysfunction syndrome in critical illness. Extracellular RNAs play a role in cell-to-cell communication during physiological and disease processes but they are rarely studied in ML. W...

journal_title：Lymphatic research and biology

authors： Hong J,Blenkiron C,Tsai P,Premkumar R,Nachkebia S,Tun SM,Petzer A,Windsor JA,Hickey AJ,Phillips AR

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Previous studies suggest that rhythmic compression of the abdomen (abdominal lymphatic pump techniques, LPT) enhances immunity and resistance to infectious disease, but direct evidence of this has not been documented. In this study, the thoracic duct of eight anesthetized mongrel dogs was catheterized, so th...

journal_title：Lymphatic research and biology

authors： Hodge LM,King HH,Williams AG Jr,Reder SJ,Belavadi T,Simecka JW,Stoll ST,Downey HF

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Near-infrared fluorescence (NIRF) imaging is a new imaging technique that is used to visualize lymphatic vessels in humans. It has a high spatial and temporal resolution, allowing real-time visualization of lymphatic flow. METHODS AND RESULTS:The current study investigated the intra- and inter-individual va...

journal_title：Lymphatic research and biology

authors： Groenlund JH,Telinius N,Skov SN,Hjortdal V

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Surgical manipulations of the axilla may cause a condition known as Axillary Web Syndrome (AWS). The systems compromised and the sequence of events leading to this syndrome remains unknown. This study evaluated clinical, surgical, and vascular factors associated with onset and duration of AWS after breast ca...

journal_title：Lymphatic research and biology

authors： Furlan C,Matheus CN,Jales RM,Derchain S,Sarian LO

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:The aim of the article was to assess risk factors and to analyze methods applied in the prevention and treatment of lower limb edema in pregnant women with a particular focus on compression therapy and exercise. MATERIALS AND METHODS:Fifty-four women during the early 24-hour period following delivery were as...

journal_title：Lymphatic research and biology

authors： Ochalek K,Pacyga K,Curyło M,Frydrych-Szymonik A,Szygula Z

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Tissue dielectric constant (TDC) and spot bioimpedance measurement (BIA) have a role in the assessment of tissue composition changes in breast cancer-related lymphedema (BCRL). Our aims were to determine whether TDC and spot BIA measures could detect inter-limb differences in BCRL, explore the relationship b...

journal_title：Lymphatic research and biology

authors： Czerniec SA,Ward LC,Kilbreath SL

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Lymphedema leads to adipose tissue deposition. Water-fat magnetic resonance imaging (MRI) can quantify and localize fat and water. The presence of excess fat and excess water/muscle in the subfascial compartment of the lymphedematous limb has not been investigated before. The aim of this study was to investi...

journal_title：Lymphatic research and biology

authors： Hoffner M,Peterson P,Månsson S,Brorson H

更新日期：2018-04-01 00:00:00

abstract：:Pediatric hepatic angiosarcoma is a very rare malignant vascular tumor. A few cases have shown pediatric hepatic angiosarcoma occurring on a background of preexisting vascular lesions. We report the case of a newborn girl who presented extensive limbs and upper trunk cutaneous mixed vascular malformations at birth. Th...

journal_title：Lymphatic research and biology

authors： Al Dhaybi R,Agoumi M,Powell J,Dubois J,Kokta V

更新日期：2010-09-01 00:00:00

abstract：:The vasculature of the central nervous system (CNS) is highly specialized with a blood-brain-barrier, reciprocal neuroepithelial-endothelial cell interactions and extensive pericyte coverage. Developmentally, numerous important signaling pathways participate in CNS angiogenesis to orchestrate the precise timing and sp...

journal_title：Lymphatic research and biology

authors： Mancuso MR,Kuhnert F,Kuo CJ

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Lymphedema is the abnormal accumulation of protein-rich fluid in the interstitial space. Primary lymphedema is a rare genetic condition with both autosomal dominant and autosomal recessive modes of inheritance. Three genes, FLT4 (VEGFR3), FOXC2, and SOX18 cause varying forms of primary lymphedema. In industr...

journal_title：Lymphatic research and biology

authors： Finegold DN,Schacht V,Kimak MA,Lawrence EC,Foeldi E,Karlsson JM,Baty CJ,Ferrell RE

更新日期：2008-01-01 00:00:00

abstract：: Background: Local tissue water in patients with breast cancer-related lymphedema (BCRL) can be assessed by measurement of the tissue dielectric constant using the MoistureMeterD Compact® (MMDC) device, or by performing the pitting test. Although these assessment methods ar...

journal_title：Lymphatic research and biology

authors： De Vrieze T,Gebruers N,Nevelsteen I,De Groef A,Tjalma WAA,Thomis S,Dams L,Van der Gucht E,Penen F,Devoogdt N

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Studies of lymphatic function often employ collecting lymphatic vessels that exhibit large-amplitude, spontaneous contractions. Data from such preparations have been analyzed using cardiac pump analogies that require accurate determination of vascular dimensions, including external (OD) and internal (ID) dia...

journal_title：Lymphatic research and biology

authors： Davis MJ,Zawieja DC,Gashev AA

更新日期：2006-04-01 00:00:00

abstract：: Background: The use of bioimpedance spectroscopy (BIS) for the detection of unilateral upper limb lymphedema is growing. Currently, normatively determined diagnostic thresholds using bioimpedance are available for females only. It is unclear if they are suitable for males ...

journal_title：Lymphatic research and biology

authors： Xie AZT,Lee MJ,Dylke E

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Lymph is pumped through the collecting lymphatic vessels by both intrinsic and extrinsic forces, propelling it downstream back into circulation. The intrinsic lymph pump relies on the spontaneous contraction of lymphatic muscles to generate the force of pumping lymph (P(lp)). However, the association between...

journal_title：Lymphatic research and biology

authors： Saito T,Unno N,Yamamoto N,Inuzuka K,Tanaka H,Sano M,Sugisawa R,Katahashi K,Konno H

更新日期：2015-06-01 00:00:00

abstract：:The objective of the study was to evaluate the intra- and inter-rater reliability of bioimpedance in determining upper limb volume in women with lymphedema resulting from breast cancer treatment, as well as its correlation with the upper limb volume calculated by circumferential measurement. A blind cross-sectional st...

journal_title：Lymphatic research and biology

authors： Ferro AP,Ferreira VTK,Rezende MS,de Souza TR,Almeida AM,Guirro RRJ,Guirro ECO

更新日期：2018-06-01 00:00:00