Information flow between interacting human brains: Identification, validation, and relationship to social expertise.

Abstract:

:Social interactions are fundamental for human behavior, but the quantification of their neural underpinnings remains challenging. Here, we used hyperscanning functional MRI (fMRI) to study information flow between brains of human dyads during real-time social interaction in a joint attention paradigm. In a hardware setup enabling immersive audiovisual interaction of subjects in linked fMRI scanners, we characterize cross-brain connectivity components that are unique to interacting individuals, identifying information flow between the sender's and receiver's temporoparietal junction. We replicate these findings in an independent sample and validate our methods by demonstrating that cross-brain connectivity relates to a key real-world measure of social behavior. Together, our findings support a central role of human-specific cortical areas in the brain dynamics of dyadic interactions and provide an approach for the noninvasive examination of the neural basis of healthy and disturbed human social behavior with minimal a priori assumptions.

authors

Bilek E,Ruf M,Schäfer A,Akdeniz C,Calhoun VD,Schmahl C,Demanuele C,Tost H,Kirsch P,Meyer-Lindenberg A

doi

10.1073/pnas.1421831112

subject

Has Abstract

pub_date

2015-04-21 00:00:00

pages

5207-12

issue

16

eissn

0027-8424

issn

1091-6490

pii

1421831112

journal_volume

112

pub_type

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