Abstract：
:We introduce CIBERSORT, a method for characterizing cell composition of complex tissues from their gene expression profiles. When applied to enumeration of hematopoietic subsets in RNA mixtures from fresh, frozen and fixed tissues, including solid tumors, CIBERSORT outperformed other methods with respect to noise, unknown mixture content and closely related cell types. CIBERSORT should enable large-scale analysis of RNA mixtures for cellular biomarkers and therapeutic targets (http://cibersort.stanford.edu/).
journal_name
Nat Methodsjournal_title
Nature methodsauthors
Newman AM,Liu CL,Green MR,Gentles AJ,Feng W,Xu Y,Hoang CD,Diehn M,Alizadeh AAdoi
10.1038/nmeth.3337subject
Has Abstractpub_date
2015-05-01 00:00:00pages
453-7issue
5eissn
1548-7091issn
1548-7105pii
nmeth.3337journal_volume
12pub_type
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