Abstract：
:High-speed, large-scale three-dimensional (3D) imaging of neuronal activity poses a major challenge in neuroscience. Here we demonstrate simultaneous functional imaging of neuronal activity at single-neuron resolution in an entire Caenorhabditis elegans and in larval zebrafish brain. Our technique captures the dynamics of spiking neurons in volumes of ∼700 μm × 700 μm × 200 μm at 20 Hz. Its simplicity makes it an attractive tool for high-speed volumetric calcium imaging.
journal_name
Nat Methodsjournal_title
Nature methodsauthors
Prevedel R,Yoon YG,Hoffmann M,Pak N,Wetzstein G,Kato S,Schrödel T,Raskar R,Zimmer M,Boyden ES,Vaziri Adoi
10.1038/nmeth.2964subject
Has Abstractpub_date
2014-07-01 00:00:00pages
727-730issue
7eissn
1548-7091issn
1548-7105journal_volume
11pub_type
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