Subsistence strategies in traditional societies distinguish gut microbiomes.

abstract：:Memory consolidation requires a timely controlled interplay between the hippocampus, a brain region important for memory formation, and the cortex, a region recruited for memory storage. Here we show that memory consolidation is associated with specific epigenetic modifications on histone proteins that have a distinct...

journal_title：Nature communications

authors： Gräff J,Woldemichael BT,Berchtold D,Dewarrat G,Mansuy IM

更新日期：2012-01-01 00:00:00

abstract：:Molecularly targeted therapies for advanced prostate cancer include castration modalities that suppress ligand-dependent transcriptional activity of the androgen receptor (AR). However, persistent AR signalling undermines therapeutic efficacy and promotes progression to lethal castration-resistant prostate cancer (CRP...

journal_title：Nature communications

authors： Henzler C,Li Y,Yang R,McBride T,Ho Y,Sprenger C,Liu G,Coleman I,Lakely B,Li R,Ma S,Landman SR,Kumar V,Hwang TH,Raj GV,Higano CS,Morrissey C,Nelson PS,Plymate SR,Dehm SM

更新日期：2016-11-29 00:00:00

abstract：:Axonemal dyneins are tethered to doublet microtubules inside cilia to drive ciliary beating, a process critical for cellular motility and extracellular fluid flow. Axonemal dyneins are evolutionarily and biochemically distinct from cytoplasmic dyneins that transport cargo, and the mechanisms regulating their localizat...

journal_title：Nature communications

authors： Walton T,Wu H,Brown A

更新日期：2021-01-20 00:00:00

abstract：:Evolution of supramolecular chirality from self-assembly of achiral compounds and control over its handedness is closely related to the evolution of life and development of supramolecular materials with desired handedness. Here we report a system where the entire process of induction, control and locking of supramolec...

journal_title：Nature communications

authors： Kim J,Lee J,Kim WY,Kim H,Lee S,Lee HC,Lee YS,Seo M,Kim SY

更新日期：2015-04-23 00:00:00

abstract：:Synthesis of ethanol from non-petroleum carbon resources via syngas (a mixture of H2 and CO) is an important but challenging research target. The current conversion of syngas to ethanol suffers from low selectivity or multiple processes with high energy consumption. Here, we report a high-selective conversion of synga...

journal_title：Nature communications

authors： Kang J,He S,Zhou W,Shen Z,Li Y,Chen M,Zhang Q,Wang Y

更新日期：2020-02-11 00:00:00

abstract：:Understanding how immune challenges elicit different responses is critical for diagnosing and deciphering immune regulation. Using a modular strategy to interpret the complex transcriptional host response in mouse models of infection and inflammation, we show a breadth of immune responses in the lung. Lung immune sign...

journal_title：Nature communications

authors： Singhania A,Graham CM,Gabryšová L,Moreira-Teixeira L,Stavropoulos E,Pitt JM,Chakravarty P,Warnatsch A,Branchett WJ,Conejero L,Lin JW,Davidson S,Wilson MS,Bancroft G,Langhorne J,Frickel E,Sesay AK,Priestnall SL,Herbert

更新日期：2019-06-28 00:00:00

abstract：:Grain rotation is a well-known phenomenon during high (homologous) temperature deformation and recrystallization of polycrystalline materials. In recent years, grain rotation has also been proposed as a plasticity mechanism at low temperatures (for example, room temperature for metals), especially for nanocrystalline ...

journal_title：Nature communications

authors： Wang L,Teng J,Liu P,Hirata A,Ma E,Zhang Z,Chen M,Han X

更新日期：2014-07-17 00:00:00

abstract：:Incited by public fascination and engineering application, water-skipping of rigid stones and spheres has received considerable study. While these objects can be coaxed to ricochet, elastic spheres demonstrate superior water-skipping ability, but little is known about the effect of large material compliance on water i...

journal_title：Nature communications

authors： Belden J,Hurd RC,Jandron MA,Bower AF,Truscott TT

更新日期：2016-02-04 00:00:00

abstract：:Ciliary membrane composition is controlled by transition zone (TZ) proteins such as RPGRIP1, RPGRIPL and NPHP4, which are vital for balanced coordination of diverse signalling systems like the Sonic hedgehog (Shh) pathway. Activation of this pathway involves Shh-induced ciliary accumulation of Smoothened (SMO), which ...

journal_title：Nature communications

authors： Schou KB,Mogensen JB,Morthorst SK,Nielsen BS,Aleliunaite A,Serra-Marques A,Fürstenberg N,Saunier S,Bizet AA,Veland IR,Akhmanova A,Christensen ST,Pedersen LB

更新日期：2017-01-30 00:00:00

abstract：:An industrial process for the selective activation of methane under mild conditions would be highly valuable for controlling emissions to the environment and for utilizing vast new sources of natural gas. The only selective catalysts for methane activation and conversion to methanol under mild conditions are methane m...

journal_title：Nature communications

authors： Blanchette CD,Knipe JM,Stolaroff JK,DeOtte JR,Oakdale JS,Maiti A,Lenhardt JM,Sirajuddin S,Rosenzweig AC,Baker SE

更新日期：2016-06-15 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Giulimondi F,Digiacomo L,Pozzi D,Palchetti S,Vulpis E,Capriotti AL,Chiozzi RZ,Laganà A,Amenitsch H,Masuelli L,Peruzzi G,Mahmoudi M,Screpanti I,Zingoni A,Caracciolo G

更新日期：2020-03-31 00:00:00

abstract：:Soil microorganisms dominate terrestrial biogeochemical cycles; however, we know very little about their spatial distribution and how changes in the distributions of specific groups of microbes translate into landscape and global patterns of biogeochemical processes. In this paper, we use a nested sampling scheme at s...

journal_title：Nature communications

authors： King AJ,Freeman KR,McCormick KF,Lynch RC,Lozupone C,Knight R,Schmidt SK

更新日期：2010-08-10 00:00:00

abstract：:According to the clonal evolution model, tumour growth is driven by competing subclones in somatically evolving cancer cell populations, which gives rise to genetically heterogeneous tumours. Here we present a comparative targeted deep-sequencing approach combined with a customised statistical algorithm, called deepSN...

journal_title：Nature communications

authors： Gerstung M,Beisel C,Rechsteiner M,Wild P,Schraml P,Moch H,Beerenwinkel N

更新日期：2012-05-01 00:00:00

abstract：:In order to model realistic quantum devices it is necessary to simulate quantum systems strongly coupled to their environment. To date, most understanding of open quantum systems is restricted either to weak system-bath couplings or to special cases where specific numerical techniques become effective. Here we present...

journal_title：Nature communications

authors： Strathearn A,Kirton P,Kilda D,Keeling J,Lovett BW

更新日期：2018-08-20 00:00:00

abstract：:Traditionally, molecular assembly pathways for viruses are inferred from high resolution structures of purified stable intermediates, low resolution images of cell sections and genetic approaches. Here, we directly visualise an unsuspected 'single shelled' intermediate for a mammalian orthoreovirus in cryo-preserved i...

journal_title：Nature communications

authors： Sutton G,Sun D,Fu X,Kotecha A,Hecksel CW,Clare DK,Zhang P,Stuart DI,Boyce M

更新日期：2020-09-07 00:00:00

abstract：:Self-induced electricity, including lightning, is often observed in dusty atmospheres. However, the physical mechanisms leading to this phenomenon remain elusive as they are remarkably challenging to determine due to the high complexity of the multi-phase turbulent flows involved. Using a fast multi-pole method in dir...

journal_title：Nature communications

authors： Di Renzo M,Urzay J

更新日期：2018-04-26 00:00:00

abstract：:MCR-1 is a lipid A modifying enzyme that confers resistance to the antibiotic colistin. Here, we analyse the impact of MCR-1 expression on E. coli morphology, fitness, competitiveness, immune stimulation and virulence. Increased expression of mcr-1 results in decreased growth rate, cell viability, competitive ability ...

journal_title：Nature communications

authors： Yang Q,Li M,Spiller OB,Andrey DO,Hinchliffe P,Li H,MacLean C,Niumsup P,Powell L,Pritchard M,Papkou A,Shen Y,Portal E,Sands K,Spencer J,Tansawai U,Thomas D,Wang S,Wang Y,Shen J,Walsh T

更新日期：2017-12-12 00:00:00

abstract：:Global fish production (capture and aquaculture) has increased quickly, which has altered global flows of phosphorus (P). Here we show that in 2016, [Formula: see text] Tg P yr-1 (mean and interquartile range) was applied in aquaculture to increase fish production; while [Formula: see text] Tg P yr-1 was removed from ...

journal_title：Nature communications

authors： Huang Y,Ciais P,Goll DS,Sardans J,Peñuelas J,Cresto-Aleina F,Zhang H

更新日期：2020-01-17 00:00:00

abstract：:Hydrogen spillover phenomenon is well-documented in hydrogenation catalysis but still highly disputed in hydrogen storage. Until now, the existence of hydrogen spillover through metal-organic frameworks (MOFs) remains a topic of ongoing debate and how far the split hydrogen atoms diffuse in such materials is unknown. ...

journal_title：Nature communications

authors： Zhan G,Zeng HC

更新日期：2018-09-17 00:00:00

abstract：:Tunneling is a fundamental quantum process with no classical equivalent, which can compete with Coulomb interactions to give rise to complex phenomena. Phosphorus dopants in silicon can be placed with atomic precision to address the different regimes arising from this competition. However, they exploit wavefunctions r...

journal_title：Nature communications

authors： Voisin B,Bocquel J,Tankasala A,Usman M,Salfi J,Rahman R,Simmons MY,Hollenberg LCL,Rogge S

更新日期：2020-11-30 00:00:00

abstract：:Cells couple growth with division and regulate size in response to nutrient availability. In rod-shaped fission yeast, cell-size control occurs at mitotic commitment. An important regulator is the DYRK-family kinase Pom1, which forms gradients from cell poles and inhibits the mitotic activator Cdr2, itself localized a...

journal_title：Nature communications

authors： Kelkar M,Martin SG

更新日期：2015-10-07 00:00:00

abstract：:Metal oxides with a tunnelled structure are attractive as charge storage materials for rechargeable batteries and supercapacitors, since the tunnels enable fast reversible insertion/extraction of charge carriers (for example, lithium ions). Common synthesis methods can introduce large cations such as potassium, barium...

journal_title：Nature communications

authors： Yuan Y,Zhan C,He K,Chen H,Yao W,Sharifi-Asl S,Song B,Yang Z,Nie A,Luo X,Wang H,Wood SM,Amine K,Islam MS,Lu J,Shahbazian-Yassar R

更新日期：2016-11-21 00:00:00

abstract：:The success of protein evolution campaigns is strongly dependent on the sequence context in which mutations are introduced, stemming from pervasive non-additive interactions between a protein's amino acids ('intra-gene epistasis'). Our limited understanding of such epistasis hinders the correct prediction of the funct...

journal_title：Nature communications

authors： Zurek PJ,Knyphausen P,Neufeld K,Pushpanath A,Hollfelder F

更新日期：2020-11-26 00:00:00

abstract：:On-surface chemical reactions hold the potential for manufacturing nanoscale structures directly onto surfaces by linking carbon atoms in a single-step reaction. To fabricate more complex and functionalized structures, the control of the on-surface chemical reactions must be developed significantly. Here, we present a...

journal_title：Nature communications

authors： Kawai S,Haapasilta V,Lindner BD,Tahara K,Spijker P,Buitendijk JA,Pawlak R,Meier T,Tobe Y,Foster AS,Meyer E

更新日期：2016-09-13 00:00:00

abstract：:Herbivore-induced volatile organic compounds prime non-attacked plant tissues to respond more strongly to subsequent attacks. However, the key volatiles that trigger this primed state remain largely unidentified. In maize, the release of the aromatic compound indole is herbivore-specific and occurs earlier than other ...

journal_title：Nature communications

authors： Erb M,Veyrat N,Robert CA,Xu H,Frey M,Ton J,Turlings TC

更新日期：2015-02-16 00:00:00

abstract：:Hydrothermal synthesis is challenging in metal oxide systems with diverse polymorphism, as reaction products are often sensitive to subtle variations in synthesis parameters. This sensitivity is rooted in the non-equilibrium nature of low-temperature crystallization, where competition between different metastable phas...

journal_title：Nature communications

authors： Chen BR,Sun W,Kitchaev DA,Mangum JS,Thampy V,Garten LM,Ginley DS,Gorman BP,Stone KH,Ceder G,Toney MF,Schelhas LT

更新日期：2018-06-29 00:00:00

abstract：:Because of the potential impact on agriculture and other key human activities, efforts have been dedicated to the local control of precipitation. The most common approach consists of dispersing small particles of dry ice, silver iodide, or other salts in the atmosphere. Here we show, using field experiments conducted ...

journal_title：Nature communications

authors： Henin S,Petit Y,Rohwetter P,Stelmaszczyk K,Hao ZQ,Nakaema WM,Vogel A,Pohl T,Schneider F,Kasparian J,Weber K,Wöste L,Wolf JP

更新日期：2011-08-30 00:00:00

abstract：:Wilms tumor gene on the X chromosome (WTX) is a putative tumor suppressor gene in Wilms tumor, but its expression and functions in other tumors are unclear. Colorectal cancer (CRC) is the third leading cause of cancer-related deaths in women and the second leading cause in men in the United States. We demonstrated tha...

journal_title：Nature communications

authors： Zhu GF,Xu YW,Li J,Niu HL,Ma WX,Xu J,Zhou PR,Liu X,Ye DL,Liu XR,Yan T,Zhai WK,Xu ZJ,Liu C,Wang L,Wang H,Luo JM,Liu L,Li XQ,Guo S,Jiang HP,Shen P,Lin HK,Yu DH,Ding YQ,Zhang QL

更新日期：2019-01-10 00:00:00

abstract：:Serial X-ray crystallography allows macromolecular structure determination at both X-ray free electron lasers (XFELs) and, more recently, synchrotron sources. The time resolution for serial synchrotron crystallography experiments has been limited to millisecond timescales with monochromatic beams. The polychromatic, "...

journal_title：Nature communications

authors： Meents A,Wiedorn MO,Srajer V,Henning R,Sarrou I,Bergtholdt J,Barthelmess M,Reinke PYA,Dierksmeyer D,Tolstikova A,Schaible S,Messerschmidt M,Ogata CM,Kissick DJ,Taft MH,Manstein DJ,Lieske J,Oberthuer D,Fischetti RF,C

更新日期：2017-11-03 00:00:00

abstract：:Hypoxia occurs when limited oxygen supply impairs physiological functions and is a pathological hallmark of many diseases including cancer and ischemia. Thus, detection of hypoxia can guide treatment planning and serve as a predictor of patient prognosis. Unfortunately, current methods suffer from invasiveness, poor r...

journal_title：Nature communications

authors： Knox HJ,Hedhli J,Kim TW,Khalili K,Dobrucki LW,Chan J

更新日期：2017-11-27 00:00:00