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One-pot, three-component reaction using modified Julia reagents: a facile synthesis of 4,5-disubstituted 1,2,3-(NH)-triazoles in a wet organic solvent.

Abstract：

:A new one-pot, three component reaction involving the use of Julia reagent, aldehyde, and sodium azide was developed for the efficient synthesis of N-unsubstituted 1,2,3-triazoles. This reaction could be carried out under mild reaction conditions without any precaution, and broad scope of substrates, both respect to Julia reagents and aldehydes, could be applied in this reaction system in generation of a small library of title compounds.

journal_name

ACS Comb Sci

journal_title

ACS combinatorial science

authors

Chai H,Guo R,Yin W,Cheng L,Liu R,Chu C

doi

10.1021/co5001597

subject

Has Abstract

pub_date

2015-03-09 00:00:00

pages

147-51

issue

3

eissn

2156-8952

issn

2156-8944

journal_volume

17

pub_type

杂志文章

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