Abstract:
:We report the first example of venting-while-heating microwave-assisted synthesis of a small library of 3-arylthioindoles. Compounds were prepared in excellent isolated yields (90-98%) within 4 min in a closed vessel by treating indoles with disulfides in the presence of sodium hydride in anhydrous N,N-dimethylformamide. The method was not affected by electron-donating and -withdrawing substituents both on 3-arylthio moiety and at 2- and 5-positions of the indole nucleus.
journal_name
ACS Comb Scijournal_title
ACS combinatorial scienceauthors
La Regina G,Gatti V,Famiglini V,Piscitelli F,Silvestri Rdoi
10.1021/co200165jsubject
Has Abstractpub_date
2012-04-09 00:00:00pages
258-62issue
4eissn
2156-8952issn
2156-8944journal_volume
14pub_type
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