Abstract:
:Adleman's illustration of molecular computing using DNA paved the way toward an entirely new direction of computing (Adleman, L. M. Science 1994, 266, 1021). The exponential time complex combinatorial problem on a traditional computer turns out to be a separation problem involving a polynomial number of steps in DNA computing experiments. Despite being a promising concept, the implementations of existing DNA computing procedures were restricted only to the smaller size formulations. In this work, we demonstrate a structure assisted DNA computing procedure on a bigger size Hamiltonian cycle problem involving 18 vertices. The developed model involves the formation and digestion of circular structure DNA, iteratively over multiple stages to eliminate the incorrect solutions to the given combinatorial problem. A high accuracy is obtained compared to other structure assisted models, which enable one to solve the bigger size problems.
journal_name
ACS Comb Scijournal_title
ACS combinatorial scienceauthors
Sharma D,Ramteke Mdoi
10.1021/acscombsci.9b00150subject
Has Abstractpub_date
2020-05-11 00:00:00pages
225-231issue
5eissn
2156-8952issn
2156-8944journal_volume
22pub_type
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