Pancreatic cancer, treatment options, and GI-4000.

abstract：:Background: The expansion of available vaccines in recent years has increased the overall costs of the vaccine program and put pressure on providers responsible for vaccination. In England in 2016-17, GP practices responsible for vaccinating their local population were paid £227 million. However, the costs to general ...

journal_title：Human vaccines & immunotherapeutics

authors： Crocker-Buque T,Mohan K,Ramsay M,Edelstein M,Mounier-Jack S

更新日期：2019-01-01 00:00:00

abstract：:Abrin, obtained from the seeds of Abrus precatorius plant, is a potent toxin belonging to the family of type II ribosome-inactivating proteins. Recently, a recombinant vaccine consisting of the A subunits of abrin and its homolog Abrus precatorius agglutinin (APA) was demonstrated to protect mice from abrin lethality....

journal_title：Human vaccines & immunotherapeutics

authors： Kumar MS,Karande AA

更新日期：2016-01-01 00:00:00

abstract：:Most influenza vaccines in Mexico are trivalent, containing two influenza A strains and a single B strain. Quadrivalent influenza vaccines (QIVs) extend protection by including an additional B strain to cover both co-circulating B lineages. Here, we retrospectively estimated how a switch to QIV in Mexico would have im...

journal_title：Human vaccines & immunotherapeutics

authors： Ruiz-Palacios GM,Beigel JH,Guerrero ML,Bellier L,Tamayo R,Cervantes P,Alvarez FP,Galindo-Fraga A,Aguilar-Ituarte F,Lopez JG

更新日期：2020-04-02 00:00:00

abstract：:Japanese encephalitis (JE) is a serious public health concern in most of Asia. The disease is caused by JE virus (JEV), a flavivirus transmitted by Culex mosquitoes. Several vaccines have been developed to control JE in endemic areas as well as to protect travelers and military personnel who visit or are commissioned ...

journal_title：Human vaccines & immunotherapeutics

authors： Hegde NR,Gore MM

更新日期：2017-06-03 00:00:00

abstract：INTRODUCTION:Enterovirus A71(EV-A71)-associated hand, foot, and mouth disease (HFMD) has been reported worldwide, and poses a particularly heavy burden on patients, families, and society in China. Three Chinese companies have licensed inactivated EV-A71 vaccines, all of which have demonstrated good efficacy for prevent...

journal_title：Human vaccines & immunotherapeutics

authors： Wang X,An Z,Huo D,Jia L,Li J,Yang Y,Liang Z,Wang Q,Wang H

更新日期：2019-01-01 00:00:00

abstract：:Background: We performed a systematic review to evaluate factors affecting uptake of rotavirus vaccine amongst physicians, parents and health system. Methods: We identified 15 studies that met the inclusion criteria from 790 screened studies published between Jan 2005 to Jan 2016. Results: Perceived severity of rotavi...

journal_title：Human vaccines & immunotherapeutics

authors： Apte A,Roy S,Bavdekar A,Juvekar S,Hirve S

更新日期：2018-01-01 00:00:00

abstract：:This randomized trial conducted in France compared intramuscular (IM) and subcutaneous (SC) administration of two doses of a measles, mumps, rubella, and varicella (MMRV) combination vaccine (ProQuad®) administered one month apart to 405 children 12-18 months of age (NCT00402831). The 2-dose regimen of MMRV administer...

journal_title：Human vaccines & immunotherapeutics

authors： Haas H,Richard P,Eymin C,Fiquet A,Kuter B,Soubeyrand B

更新日期：2019-01-01 00:00:00

abstract：:Varicella is a potentially serious infectious disease caused by Varicella-Zoster Virus (VZV). In Italy childhood varicella vaccine have gradually introduced into national immunization program since 2003 and from 2017 a two-doses schedule has been stated nationally for all newborns and has become compulsory for school ...

journal_title：Human vaccines & immunotherapeutics

authors： Balbi O,Baldi S,Rizza S,Pietroiusti A,Perrone S,Coppeta L

更新日期：2020-07-09 00:00:00

abstract：:Measles virus (MV) is the only human virus within the morbillivirus genus of the Paramyxoviridae. The veterinary members are canine distemper virus (CDV), peste des petits ruminants virus (PPRV), Rinderpest Virus (RPV) as well as the marine morbilliviruses phocine distemper virus (PDV), dolphin morbillivirus (DMV) and...

journal_title：Human vaccines & immunotherapeutics

authors： Cosby SL,Weir L

更新日期：2018-01-02 00:00:00

abstract：:The 4-component vaccine 4CMenB, developed against invasive disease caused by meningococcal serogroup B, is approved for use in infants in several countries worldwide. 4CMenB is mostly used as 3 + 1 schedule, except for the UK, where a 2 + 1 schedule is used, and where the vaccine showed an effectiveness of 82.9%. Here...

journal_title：Human vaccines & immunotherapeutics

authors： Biolchi A,Tomei S,Santini L,Welsch JA,Toneatto D,Gaitatzis N,Bai X,Borrow R,Giuliani MM,Mori E,Pizza M

更新日期：2019-01-01 00:00:00

abstract：:For the 2010/11 influenza season the prenatal vaccination program was extended to all women in England and Wales irrespective of gestational age--this was a considerable shift in practice for both pregnant women and healthcare providers where the emphasis previously had been only on targeted vaccination for pregnant w...

journal_title：Human vaccines & immunotherapeutics

authors： Baxter D

更新日期：2013-06-01 00:00:00

abstract：:Hepatitis B vaccine is the most effective strategy to control hepatitis B virus (HBV) infection and disease. It is considered that an anti-HBs (antibodies against HBV surface antigen) titer >10 mIU/ml, measured shortly after a complete vaccination schedule, provides protection against infection. Approximately 4-10% of...

journal_title：Human vaccines & immunotherapeutics

authors： Cassaniti I,Calarota SA,Adzasehoun KM,Chiesa A,Comolli G,Parea M,Baldanti F

更新日期：2016-11-01 00:00:00

abstract：:During 2009-2010, a large US mumps outbreak occurred affecting two-dose vaccinated 9th-12th grade Orthodox Jewish boys attending all-male yeshivas (private, traditional Jewish schools). Our objective was to understand mumps transmission dynamics in this well-vaccinated population. We surveyed 9th-12th grade male yeshi...

journal_title：Human vaccines & immunotherapeutics

authors： Fiebelkorn AP,Rosen JB,Brown C,Zimmerman CM,Renshowitz H,D'Andrea C,Gallagher KM,Harpaz R,Zucker JR

更新日期：2013-01-01 00:00:00

abstract：:Attenuated measles virus (MV) is one of the most effective and safe vaccines available, making it attractive candidate vector to prevent infectious diseases. Attenuated MV have acquired the ability to use the complement regulator CD46 as a major receptor to mediate virus entry and intercellular fusion. Therefore, atte...

journal_title：Human vaccines & immunotherapeutics

authors： Baldo A,Galanis E,Tangy F,Herman P

更新日期：2016-05-03 00:00:00

abstract：BACKGROUND:Many low- to middle-income countries have completed or are in the process of transitioning from high or intermediate to low endemicity for hepatitis A virus (HAV). Because the risk of severe hepatitis A disease increases with age at infection, decreased incidence that leaves older children and adults suscept...

journal_title：Human vaccines & immunotherapeutics

authors： Van Effelterre T,Guignard A,Marano C,Rojas R,Jacobsen KH

更新日期：2017-08-03 00:00:00

abstract：:Zika is an arboviral illness caused by infection with the Zika flavivirus. Transmission most commonly occurs during a feeding event involving an infected Aedes mosquito or vertical transmission between an infected mother to her fetus. Infection outcomes range from asymptomatic to devastating neurologic injuries in chi...

journal_title：Human vaccines & immunotherapeutics

authors： Thomas SJ,Barrett A

更新日期：2020-10-02 00:00:00

abstract：:Annual influenza vaccination is recommended as a preventive measure for all patients with asthma since asthma exacerbations in children and adults are associated to viral infections including influenza. There is concern about the adequate immune response in asthmatics with ICS treatment. The production of antibodies t...

journal_title：Human vaccines & immunotherapeutics

authors： Velasco-Medina AA,García-León ML,Velázquez-Sámano G,Wong-Chew RM

更新日期：2020-05-21 00:00:00

abstract：:The impact of seasonal influenza has been under-appreciated in Asia and surveillance data lags in most other regions. The variety of influenza circulation patterns in Asia - largely due to the range of climates - has also only recently been recognized and its effect on the burden of disease is not fully understood. Re...

journal_title：Human vaccines & immunotherapeutics

authors： Young BE,Chen M

更新日期：2020-07-02 00:00:00

abstract：:There is a need for both new and improved vaccination formulations for a range of diseases for which current vaccines are either inadequate or non-existent. Biodegradable polymer-based vaccines fulfill many of the desired properties in achieving effective long-term protection in a manner that is safe, economical, and ...

journal_title：Human vaccines & immunotherapeutics

authors： Joshi VB,Geary SM,Salem AK

更新日期：2013-12-01 00:00:00

abstract：:Hepatitis A is a vaccine-preventable infection caused by the HA virus (HAV) with transitional to intermediate endemicity in China. An inactivated vaccine first licensed in China in 2010 (Avaxim® 80U Pediatric) is indicated for primary and booster vaccination in children from 12 months to 15 years of age. This Phase IV...

journal_title：Human vaccines & immunotherapeutics

authors： Shi N,Rasuli A,Thollot Y

更新日期：2019-01-01 00:00:00

abstract：:The practice of passive immunization with human immune globulin (IG) for the control of communicable diseases (measles, rubella and hepatitis A) differs somewhat between Australia, the United States of America, the United Kingdom, and New Zealand despite the many similarities of these countries, including disease inci...

journal_title：Human vaccines & immunotherapeutics

authors： Young MK,Cripps AW

更新日期：2013-09-01 00:00:00

abstract：:Respiratory syncytial virus (RSV) is the most common cause of respiratory tract infections in both children and elderly people. In this study we evaluated the short- and long-term protective efficacy of a single intranasal (IN) immunization with a RSV vaccine formulation consisting of a codon-optimized fusion (F) prot...

journal_title：Human vaccines & immunotherapeutics

authors： Garg R,Latimer L,Gerdts V,Potter A,van Drunen Littel-van den Hurk S

更新日期：2017-12-02 00:00:00

abstract：:The development of a successful vaccine, which should elicit a combination of humoral and cellular responses to control or prevent infections, is the first step in protecting against infectious diseases. A vaccine may protect against bacterial, fungal, parasitic, or viral infections in animal models, but to be effecti...

journal_title：Human vaccines & immunotherapeutics

authors： Zheng Z,Diaz-Arévalo D,Guan H,Zeng M

更新日期：2018-07-03 00:00:00

abstract：:Different strategies have been proposed for the development of protein subunit vaccine candidates for tuberculosis (TB), which shows better safety than other types of candidates and the currently used Bacillus Calmette-Guérin (BCG) vaccine. In order to develop more effective protein subunits depending on the mechanism...

journal_title：Human vaccines & immunotherapeutics

authors： Teng X,Tian M,Li J,Tan S,Yuan X,Yu Q,Jing Y,Zhang Z,Yue T,Zhou L,Fan X

更新日期：2015-01-01 00:00:00

abstract：:Japanese encephalitis virus is the major cause of encephalitis in India. To control the increasing incidence and fatal outbreaks, SA 14-14-2 vaccine was introduced initially in 104 endemic districts in phased manner from 2006 to 2011. As there is no data available before 2008 on the number of Japanese encephalitis (JE...

journal_title：Human vaccines & immunotherapeutics

authors： Muniaraj M,Rajamannar V

更新日期：2019-01-01 00:00:00

abstract：:This study aimed to describe the disparities in immunization coverage between National Immunization Program (NIP) vaccines and non-NIP vaccines in Yiwu and to identify potential determinants. A face-to-face interview-based questionnaire survey among 423 migrant children born from 1 June 2010 to 31 May 2013 was conduct...

journal_title：Human vaccines & immunotherapeutics

authors： Hu Y,Luo S,Tang X,Lou L,Chen Y,Guo J

更新日期：2015-01-01 00:00:00

abstract：:Timely vaccine supply is critical during influenza pandemics but is impeded by current virus-based manufacturing methods. The 2009 H1N1/2009pdm 'swine flu' pandemic reinforced the need for innovation in pandemic vaccine design. We report on insights gained during rapid development of a pandemic vaccine based on recomb...

journal_title：Human vaccines & immunotherapeutics

authors： Honda-Okubo Y,Rajapaksha H,Sajkov D,Gordon D,Cox MMJ,Petrovsky N

更新日期：2017-06-03 00:00:00

abstract：:Overexpressed tumor-self antigens represent the largest group of candidate vaccine targets. Those exhibiting a role in oncogenesis may be some of the least studied but perhaps most promising. This review considers this subset of self antigens by highlighting vaccine efforts for some of the better known members and foc...

journal_title：Human vaccines & immunotherapeutics

authors： Bright RK,Bright JD,Byrne JA

更新日期：2014-01-01 00:00:00

abstract：:The objectives of this study were to estimate incidence density rates (IDR) of herpes zoster (HZ) and to analyze the association with sociodemographic characteristics and selected chronic medical conditions. The study cohort consisted of the adult population included in the Public Health System of the Autonomous Commu...

journal_title：Human vaccines & immunotherapeutics

authors： Esteban-Vasallo MD,Domínguez-Berjón MF,Gil-Prieto R,Astray-Mochales J,Gil de Miguel A

更新日期：2014-01-01 00:00:00

abstract：:DC-based therapeutic vaccines as a promising strategy against chronic infections and cancer have been validated in several clinical trials. However, DC-based vaccines are complex and require many in vitro manipulations, which makes this a personalized and expensive therapeutic approach. In contrast, DNA-based vaccines...

journal_title：Human vaccines & immunotherapeutics

authors： Li J,Valentin A,Beach RK,Alicea C,Felber BK,Pavlakis GN

更新日期：2015-01-01 00:00:00