The cellular and humoral immune response to influenza vaccination is comparable in asthmatic and healthy subjects.

abstract：:Cancer vaccines are designed to stimulate the body's immune system to kill tumor cells. To improve their immunogenicity, vaccine antigens must be combined with adjuvants which are able to stimulate the innate immunity and potentiate the adaptive immune response. In the last years a new generation of adjuvants mimickin...

journal_title：Human vaccines & immunotherapeutics

authors： Circelli L,Tornesello M,Buonaguro FM,Buonaguro L

更新日期：2017-08-03 00:00:00

abstract：:The present study evaluated the safety and immunogenicity of the 2013/2014 trivalent surface antigen inactivated subunit seasonal influenza virus vaccine Fluvirin® in healthy adults (18 - ≤ 60 years) and elderly (>60 years). The vaccine contained 15 µg haemagglutinin protein from each of influenza A/California/7/2009 ...

journal_title：Human vaccines & immunotherapeutics

authors： Roggelin L,Vinnemeier CD,Meyer S,Witte K,Marx L,Theeß W,Burchard GD,Rolling T,Cramer JP

更新日期：2015-01-01 00:00:00

abstract：:Influenza vaccination is the cornerstone of prophylaxis. The regulatory authorities currently annually license vaccines based on serum antibodies directed toward the major surface glycoprotein haemagglutinin (HA). The most commonly used serological test, the haemagglutination inhibition (HI) assay utilizes red blood c...

journal_title：Human vaccines & immunotherapeutics

authors： Cox RJ

更新日期：2013-02-01 00:00:00

abstract：:"Non-specific effects" of vaccines go beyond the specific protective effects against the targeted diseases. They, if real, could theoretically be beneficial, neutral or negative. This article intends to answer the following questions: Do the non-specific effects of vaccines exist? Almost certainly yes, and they can be...

journal_title：Human vaccines & immunotherapeutics

authors： Donzelli A,Schivalocchi A,Giudicatti G

更新日期：2018-01-01 00:00:00

abstract：:Malaria has long been recognized as a public health problem. At the community level, vector control, and antimalarial medicines are the main means for reducing incidence, morbidity, and mortality of malaria. A vaccine not only would bring streamlining in the prevention of morbidity and mortality from malaria but also ...

journal_title：Human vaccines & immunotherapeutics

authors： Jindal H,Bhatt B,Malik JS,Sk S,Mehta B

更新日期：2014-01-01 00:00:00

abstract：:Purpose: Gaps remain in the public's knowledge of the human papillomavirus (HPV). We assessed racial/ethnic and gender disparities in knowledge and awareness of HPV and the HPV vaccine among US adults. METHODS:Data from the Health Information National Trends Survey 4 Cycle 3 (September - December 2013) and Cycle 4 (A...

journal_title：Human vaccines & immunotherapeutics

authors： Adjei Boakye E,Tobo BB,Rojek RP,Mohammed KA,Geneus CJ,Osazuwa-Peters N

更新日期：2017-11-02 00:00:00

abstract：:Rapid production of influenza vaccine antigen is an important challenge when a new pandemic occurs. Production of recombinant antigens in plants is a quick, cost effective and up scalable new strategy for influenza vaccine production. In this study, we have characterized a recombinant influenza haemagglutinin antigen ...

journal_title：Human vaccines & immunotherapeutics

authors： Jul-Larsen Å,Madhun AS,Brokstad KA,Montomoli E,Yusibov V,Cox RJ

更新日期：2012-05-01 00:00:00

abstract：:The multicomponent meningococcal serogroup B vaccine, 4CMenB, has demonstrated effectiveness in preventing invasive MenB disease in infants and in controlling MenB outbreaks. The need for/timing of additional booster doses is not yet established. We reviewed eight studies that evaluated antibody persistence and booste...

journal_title：Human vaccines & immunotherapeutics

authors： Martinón-Torres F,Nolan T,Toneatto D,Banzhoff A

更新日期：2019-01-01 00:00:00

abstract：:During 2009-2010, a large US mumps outbreak occurred affecting two-dose vaccinated 9th-12th grade Orthodox Jewish boys attending all-male yeshivas (private, traditional Jewish schools). Our objective was to understand mumps transmission dynamics in this well-vaccinated population. We surveyed 9th-12th grade male yeshi...

journal_title：Human vaccines & immunotherapeutics

authors： Fiebelkorn AP,Rosen JB,Brown C,Zimmerman CM,Renshowitz H,D'Andrea C,Gallagher KM,Harpaz R,Zucker JR

更新日期：2013-01-01 00:00:00

abstract：:The impact of seasonal influenza has been under-appreciated in Asia and surveillance data lags in most other regions. The variety of influenza circulation patterns in Asia - largely due to the range of climates - has also only recently been recognized and its effect on the burden of disease is not fully understood. Re...

journal_title：Human vaccines & immunotherapeutics

authors： Young BE,Chen M

更新日期：2020-07-02 00:00:00

abstract：:This cross-sectional survey determined the vaccine hesitancy related to Human papillomavirus (HPV) and the determinants among parents of adolescents aged 12 and 13 years in Italy. Data was collected through a self-administered questionnaire. Two-thirds of the parents (66.7%) had heard of HPV infection and knew that th...

journal_title：Human vaccines & immunotherapeutics

authors： Della Polla G,Pelullo CP,Napolitano F,Angelillo IF

更新日期：2020-11-01 00:00:00

abstract：:The pseudo-neutralization assay (PsV) described in the current report allows for the creation of HPV18 pseudovirions in order to evaluate whether the antibody responses elicited following vaccination with Gardasil(®) are sufficient to neutralize the activity of these pseudovirions in vitro. The PsV assay evaluates a b...

journal_title：Human vaccines & immunotherapeutics

authors： Roberts C,Swoyer R,Bryan J

更新日期：2012-04-01 00:00:00

abstract：:Few studies in China focused on serotypes of Streptococcus pneumoniae in patients with invasive pneumococcal disease (IPD). We aimed at investigating the serotype distribution for IPD-causing S. pneumoniae and vaccine coverage among Chinese children and adults. This was a multicenter, observational study to collect S....

journal_title：Human vaccines & immunotherapeutics

authors： Li MC,Wang Y,Zhang H,Liu Y,Chen XJ,Yang HW,Ma P,Wang DC,Zhang BC,Dong AY,Wang CX,Li Y,Bai P,Tang WM,Wang J,Shao ZJ,Xu YC

更新日期：2020-06-12 00:00:00

abstract：:Cholangiocarcinoma (CCA) is an aggressive tumor that is associated with high rates of recurrence and mortality. This is due, in part, to the fact that CCA cells and their microenvironment secrete immunosuppressive cytokines, transforming growth factor-β (TGF-β) and interleukin-10 (IL-10), that inhibit dendritic cell (...

journal_title：Human vaccines & immunotherapeutics

authors： Thepmalee C,Panya A,Sujjitjoon J,Sawasdee N,Poungvarin N,Junking M,Yenchitsomanus PT

更新日期：2020-10-02 00:00:00

abstract：:Hepatitis B vaccination rates in China have recently increased. This study aimed to investigate infant vaccination coverage for birth cohorts from 1997 to 2011 in rural regions and to assess catch-up vaccination potential. We used questionnaire-based interviews from a cross-section of 6,529 individuals from seven prov...

journal_title：Human vaccines & immunotherapeutics

authors： Wangen KR,Zhu D,Wang J

更新日期：2019-01-01 00:00:00

abstract：:Previously we showed that 65-kDa Mycobacterium leprae heat shock protein (Hsp65) is a target for the development of a tuberculosis vaccine. Here we evaluated peripheral blood mononuclear cells (PBMC) from healthy individuals or tuberculosis patients stimulated with two forms of Hsp65 antigen, recombinant DNA that enco...

journal_title：Human vaccines & immunotherapeutics

authors： Wowk PF,Franco LH,Fonseca DMD,Paula MO,Vianna ÉDSO,Wendling AP,Augusto VM,Elói-Santos SM,Teixeira-Carvalho A,Silva FDC,Vinhas SA,Martins-Filho OA,Palaci M,Silva CL,Bonato VLD

更新日期：2017-05-04 00:00:00

abstract：:MENK, a penta-peptide is considered as being involved in the regulatory feedback loop between the immune and neuroendocrine systems, with marked modulation of various functions of human immune cells. The aim of the present work was to investigate change of lymphocyte subpopulations in peripheral blood of 50 cancer pat...

journal_title：Human vaccines & immunotherapeutics

authors： Wang Q,Gao X,Yuan Z,Wang Z,Meng Y,Cao Y,Plotnikoff NP,Griffin N,Shan F

更新日期：2014-01-01 00:00:00

abstract：:Rotavirus is the most common cause of diarrhea leading to hospitalization in young children. Rotavirus vaccines are available in Canada but have not been introduced in all provinces. In a controlled trial, 2 study sites (Prince Edward Island and the Capital District Health Authority (District 9, Nova Scotia) introduce...

journal_title：Human vaccines & immunotherapeutics

authors： Sanford C,Langley JM,Halperin SA,Zelman M,Mvrvp

更新日期：2015-01-01 00:00:00

abstract：:In tick-borne encephalitis (TBE)-endemic regions, long-term vaccination programs are efficient in preventing the disease. A booster dose of a polygeline-free inactivated TBE vaccine (Encepur Adults, GSK), administered approximately 3 years post-primary vaccination according to 1 of 3 licensed vaccination schedules in ...

journal_title：Human vaccines & immunotherapeutics

authors： Costantini M,Callegaro A,Beran J,Berlaimont V,Galgani I

更新日期：2020-09-01 00:00:00

abstract：:Research on innate immune signaling and regulation has recently focused on pathogen recognition receptors (PRRs) and their signaling pathways. Members of PRRs sense diverse microbial invasions or danger signals, and initiate innate immune signaling pathways, leading to proinflammatory cytokines production, which, in t...

journal_title：Human vaccines & immunotherapeutics

authors： Cui J,Chen Y,Wang HY,Wang RF

更新日期：2014-01-01 00:00:00

abstract：:The Advisory Committee on Immunization Practices recommends administering diphtheria, tetanus and acellular pertussis (DTaP) vaccines to children at 2, 4, 6, 15-18 months, and 4-6 y of age; preferably with the same-brand vaccine for the whole series. We estimated age-appropriate DTaP dose completion and the proportion...

journal_title：Human vaccines & immunotherapeutics

authors： Masseria C,Buikema AR,Liu F,Krishnarajah G

更新日期：2015-01-01 00:00:00

abstract：:Measles virus (MV) is the only human virus within the morbillivirus genus of the Paramyxoviridae. The veterinary members are canine distemper virus (CDV), peste des petits ruminants virus (PPRV), Rinderpest Virus (RPV) as well as the marine morbilliviruses phocine distemper virus (PDV), dolphin morbillivirus (DMV) and...

journal_title：Human vaccines & immunotherapeutics

authors： Cosby SL,Weir L

更新日期：2018-01-02 00:00:00

abstract：:Some health care providers have adopted the policy of refusing to accept into their practices families who refuse to vaccinate their children according to the standard vaccine schedule. While the frustration that drives these policies is understandable, the practice of refusing to see these families is misguided. Such...

journal_title：Human vaccines & immunotherapeutics

authors： Diekema DS

更新日期：2013-12-01 00:00:00

abstract：:Streptococcus pneumoniae causes pneumonia, meningitis, otitis media, and bacteremia. The mortality and morbidity of invasive pneumococcal disease are high among adults aged >65 years or those with underlying chronic or immunosuppressive conditions. A recent systematic review showed that patients treated with immunosup...

journal_title：Human vaccines & immunotherapeutics

authors： Kuronuma K,Takahashi H

更新日期：2019-01-01 00:00:00

abstract：:Rotavirus immunization strategies have become part of a comprehensive global public health program to control rotavirus-associated gastroenteritis, particularly in infants and children in developing countries. Several studies have reported the efficacy of different rotavirus vaccine dosing schedules, but with mixed fi...

journal_title：Human vaccines & immunotherapeutics

authors： Dai X,Bai R,Jian M,Ji Z,Ding Z,Wang F,Bi Y,Manzamaesso A,Chen T,Luo L,Liu A,Bao F

更新日期：2019-01-01 00:00:00

abstract：:Human papillomavirus (HPV) infection is common in women and also the main cause of cervical cancer. Based on a dynamic compartmental model, we aimed to evaluate the population impact and cost-effectiveness of strategies that combined cervical cancer screening and HPV schoolgirl vaccination for Chinese women. The effec...

journal_title：Human vaccines & immunotherapeutics

authors： Ma X,Harripersaud K,Smith K,Fairley CK,Zou H,Zou Z,Wang Y,Zhuang G,Zhang L

更新日期：2020-12-03 00:00:00

abstract：:In Chronic Myeloid Leukemia (CML), standard treatment consists of modern tyrosine-kinase inhibitors (TKI). Nevertheless, there is evidence that immune responses against leukemia-associated antigens (LAA) may play an important role in disease control. Dendritic cell (DC)- based immunotherapy is able to induce T cell re...

journal_title：Human vaccines & immunotherapeutics

authors： Flörcken A,Kopp J,Kölsch U,Meisel C,Dörken B,Pezzutto A,Westermann J

更新日期：2016-05-03 00:00:00

abstract：:Compared with the general population, patients with cancer in general are more susceptible to vaccine-preventable infections, either by an increased risk due to the malignancy itself or immunosuppressive treatment. The goal of immunizations in these patients is therefore to provide protection against these infections,...

journal_title：Human vaccines & immunotherapeutics

authors： Ariza-Heredia EJ,Chemaly RF

更新日期：2015-01-01 00:00:00

abstract：:The main objective of this post hoc analysis is to compare the magnitude of the immune response to HPV31/33/45/52 and 58 after a dose of 9vHPV vaccine given to naïve (previously unvaccinated) subjects and subjects previously vaccinated with a dose of 2vHPV or 4vHPV vaccine. Results from two clinical trials conducted i...

journal_title：Human vaccines & immunotherapeutics

authors： Sauvageau C,Panicker G,Unger ER,De Serres G,Schiller J,Ouakki M,Gilca V

更新日期：2020-03-03 00:00:00

abstract：:Influenza and pertussis prevention in young infants requires immunizing pregnant women and all caregivers (cocooning). We evaluated the knowledge and attitude of postpartum women about these two recommendations. A survey of predominantly Hispanic, underinsured, medically underserved postpartum women in Houston, Texas ...

journal_title：Human vaccines & immunotherapeutics

authors： Beel ER,Rench MA,Montesinos DP,Mayes B,Healy CM

更新日期：2013-09-01 00:00:00