Abstract:
:Our Patterning on Topography (PoT) printing technique enables fibronectin, laminin and other proteins to be applied to biomaterial surfaces in complex geometries that are inaccessible using traditional soft lithography techniques. Engineering combinatorial surfaces that integrate topographical and biochemical micropatterns enhances control of the biotic-abiotic interface. Here, we used this method to understand cardiomyocyte response to competing physical and chemical cues in the microenvironment.
journal_name
Nat Methodsjournal_title
Nature methodsauthors
Sun Y,Jallerat Q,Szymanski JM,Feinberg AWdoi
10.1038/nmeth.3210subject
Has Abstractpub_date
2015-02-01 00:00:00pages
134-6issue
2eissn
1548-7091issn
1548-7105pii
nmeth.3210journal_volume
12pub_type
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