Novel transcriptome assembly and improved annotation of the whiteleg shrimp (Litopenaeus vannamei), a dominant crustacean in global seafood mariculture.

abstract：:Cyclin Y (CCNY) is a member of the cyclin protein family, known to regulate cell division in proliferating cells. Interestingly, CCNY is expressed in neurons that do not undergo cell division. Here, we report that CCNY negatively regulates long-term potentiation (LTP) of synaptic strength through inhibition of AMPA re...

journal_title：Scientific reports

authors： Cho E,Kim DH,Hur YN,Whitcomb DJ,Regan P,Hong JH,Kim H,Ho Suh Y,Cho K,Park M

更新日期：2015-07-29 00:00:00

abstract：:Precisely controlling the protein-nanomaterial interactions at selective sites is crucial in engineering biomolecule composite architectures with tailored nanostructures and functions for a variety of biomedical applications. This strategy, however, is only beginning to be explored. Here, we demonstrate the facet-spec...

journal_title：Scientific reports

authors： Dong L,Luo Q,Cheng K,Shi H,Wang Q,Weng W,Han WQ

更新日期：2014-05-28 00:00:00

abstract：:Manual anthropometrics are used extensively in medical practice and epidemiological studies to assess an individual's health. However, traditional techniques reduce the complicated shape of human bodies to a series of simple size measurements and derived health indices, such as the body mass index (BMI), the waist-hip...

journal_title：Scientific reports

authors： Thelwell M,Chiu CY,Bullas A,Hart J,Wheat J,Choppin S

更新日期：2020-07-22 00:00:00

abstract：:Despite extensive research on primate cognitive function, understanding how anatomical connectivity at a neural circuit level relates to information transformation across different cortical areas remains primitive. New technology is needed to visualize inter-areal anatomical connectivity in living monkeys and to tie t...

journal_title：Scientific reports

authors： Nakamichi Y,Okubo K,Sato T,Hashimoto M,Tanifuji M

更新日期：2019-04-23 00:00:00

abstract：:In many cancers, incidence, treatment efficacy and overall prognosis vary between geographic populations. Studies disentangling the contributing factors may help in both understanding cancer biology and tailoring therapeutic interventions. Ancestry estimation in such studies should preferably be driven by genomic data...

journal_title：Scientific reports

authors： Huang Q,Baudis M

更新日期：2020-03-16 00:00:00

abstract：:A novel strategy for amplification full-length cDNA and promoter sequences has been developed using bioinformatics technology and multiplexed PCR methods in this study. The amplification of 3' ends of cDNA is performed according to the modified classic 3' RACE techniques, therein the more efficient and effective oligo...

journal_title：Scientific reports

authors： Chen N,Wang WM,Wang HL

更新日期：2016-01-13 00:00:00

abstract：:Monitoring populations and designing effective conservation actions for endangered species present significant challenges. An accurate understanding of current distribution, ecological traits and habitat requirements is imperative in formulating conservation strategies. Recent surveys on the southernmost Cuvier's Gaze...

journal_title：Scientific reports

authors： Herrera-Sánchez FJ,Gil-Sánchez JM,Álvarez B,Cancio I,de Lucas J,Arredondo Á,Díaz-Portero MÁ,Rodríguez-Siles J,Sáez JM,Pérez J,McCain E,Qninba A,Abáigar T

更新日期：2020-05-19 00:00:00

abstract：:Identifying early life-stage transitions limiting seagrass recruitment could improve our ability to target demographic processes most responsive to management. Here we determine the magnitude of life-stage transitions along gradients in physical disturbance limiting seedling establishment for the marine angiosperm, Po...

journal_title：Scientific reports

authors： Statton J,Montoya LR,Orth RJ,Dixon KW,Kendrick GA

更新日期：2017-11-01 00:00:00

abstract：:The effect of substitution of Nb by Mo in Nb40Ti30Ni30 was investigated with respect to microstructural features and hydrogen dissolution, diffusion and permeation. As-cast Nb40-xMoxTi30Ni30 (x = 0, 5, 10) alloys consist of primary bcc-Nb phase and binary eutectic (bcc-Nb + B2-TiNi). The substitution of Nb by Mo reduc...

journal_title：Scientific reports

authors： Li X,Liang X,Liu D,Chen R,Huang F,Wang R,Rettenmayr M,Su Y,Guo J,Fu H

更新日期：2017-03-16 00:00:00

abstract：:Metallic nanostructures are of immense scientific interest owing to unexpectedly strong interaction with light in deep subwavelength scales. Resonant excitations of surface and cavity plasmonic modes mediate strong light localization in nanoscale objects. Nevertheless, the role of surface plasmon-polaritons (SPP) in l...

journal_title：Scientific reports

authors： Yoon JW,Lee JH,Song SH,Magnusson R

更新日期：2014-07-14 00:00:00

abstract：:Near infrared (NIR) fluorophores like Pt-porphyrin along with analyte specific enzymes require co-encapsulation in biocompatible and biodegradable carriers in order to be transformed into implantable biosensors for efficient and continuous monitoring of analytes in patients. The main objective of this research is to d...

journal_title：Scientific reports

authors： Pandey G,Chaudhari R,Joshi B,Choudhary S,Kaur J,Joshi A

更新日期：2019-03-22 00:00:00

abstract：:PC4 is an abundant single-strand DNA binding protein that has been implicated in transcription and DNA repair. Here, we show that PC4 is involved in the cellular DNA damage response. To elucidate the role, we used the DT40 chicken B cell model, which produces clustered DNA lesions at Ig loci via the action of activati...

journal_title：Scientific reports

authors： Caldwell RB,Braselmann H,Schoetz U,Heuer S,Scherthan H,Zitzelsberger H

更新日期：2016-07-04 00:00:00

abstract：:We employed RNA sequencing analysis to reveal dysregulated lncRNAs in lung cancer utilizing 461 lung adenocarcinomas and 156 normal lung tissues from 3 separate cohorts. We found that LINC00152 was highly overexpressed in lung tumors as compared to their adjacent normal tissues. Patients with high LINC00152 expression...

journal_title：Scientific reports

authors： Feng S,Zhang J,Su W,Bai S,Xiao L,Chen X,Lin J,Reddy RM,Chang AC,Beer DG,Chen G

更新日期：2017-06-07 00:00:00

abstract：:Recent studies have shown that cellular metabolism plays an important role in regulating immune cell functions. In immune cell differentiation, both interleukin-17-producing T (Th17) cells and dendritic cells (DCs) exhibit increased glycolysis through the upregulation of glycolytic enzymes, such as hexokinase-2 (HK2)....

journal_title：Scientific reports

authors： Okano T,Saegusa J,Nishimura K,Takahashi S,Sendo S,Ueda Y,Morinobu A

更新日期：2017-02-10 00:00:00

abstract：:In this report, we propose and demonstrate an air-mode photonic crystal ring resonator (PhCRR) on silicon-on-insulator platform. Air mode is utilized to confine the optical field into photonic crystal (PhC) air holes, which is confirmed by the three-dimensional finite-difference time-domain simulation. PhCRR structure...

journal_title：Scientific reports

authors： Gao G,Zhang Y,Zhang H,Wang Y,Huang Q,Xia J

更新日期：2016-01-28 00:00:00

abstract：:Live birth is the most important concern for assisted reproductive technology (ART) patients. Therefore, in the medical reproductive centre, obstetricians often need to answer the following question: "What are the chances that I will have a healthy baby after ART treatment?" To date, our obstetricians have no referenc...

journal_title：Scientific reports

authors： Gao H,Liu DE,Li Y,Wu X,Tan H

更新日期：2021-01-11 00:00:00

abstract：:There is a variety of cases in nature when the action-reaction symmetry is broken. In particular, suitable conditions for this are realized in colloidal suspensions and complex plasmas. Since the first theories and simulations of the nonreciprocal effective interactions between microparticles in complex plasmas were p...

journal_title：Scientific reports

authors： Lisin EA,Petrov OF,Sametov EA,Vaulina OS,Statsenko KB,Vasiliev MM,Carmona-Reyes J,Hyde TW

更新日期：2020-08-12 00:00:00

abstract：:From mid-May to August 2011, extreme runoff in the Columbia River ranged from 14,000 to over 17,000 m(3)/s, more than two standard deviations above the mean for this period. The extreme runoff was the direct result of both melting of anomalously high snowpack and rainfall associated with the 2010-2011 La Niña. The eff...

journal_title：Scientific reports

authors： Mazzini PL,Risien CM,Barth JA,Pierce SD,Erofeev A,Dever EP,Kosro PM,Levine MD,Shearman RK,Vardaro MF

更新日期：2015-11-26 00:00:00

abstract：:Here we present the first report of a carbon-γ-Fe₂O₃ nanoparticle composite of mesoporous carbon, bearing COOH- and phenolic OH- functional groups on its surface, a remarkable and magnetically separable adsorbent, for the radioactive material emitted by the Fukushima Daiichi nuclear power plant accident. Contaminated ...

journal_title：Scientific reports

authors： Yamaguchi D,Furukawa K,Takasuga M,Watanabe K

更新日期：2014-08-13 00:00:00

abstract：:Predicting the risk of liver metastasis can have important prognostic and therapeutic implications, given the availability of liver-directed therapy. Uveal melanoma has a striking predisposition for liver metastasis despite the absence of anatomical proximity. Understanding its biology may uncover factors promoting li...

journal_title：Scientific reports

authors： Tsantoulis P,Delorenzi M,Bièche I,Vacher S,Mariani P,Cassoux N,Houy A,Stern MH,Roman-Roman S,Dietrich PY,Roth A,Cacheux W

更新日期：2019-11-20 00:00:00

abstract：:Efficient presentation of alien antigens triggers activation of T lymphocytes and robust host defense against invading pathogens. This pathophysiological process relies on the expression of major histocompatibility complex (MHC) molecules in antigen presenting cells such as macrophages. Aberrant MHC II transactivation...

journal_title：Scientific reports

authors： Fan Z,Li J,Li P,Ye Q,Xu H,Wu X,Xu Y

更新日期：2017-01-17 00:00:00

abstract：:Adult-onset vitelliform macular dystrophy (AVMD) is a common and benign macular degeneration which can be caused by BEST1 mutation. Here, we investigated the clinical characteristics associated with a newly identified BEST1 mutation, p.Ile38Ser and confirmed the associated physiological functional defects. The 51-year...

journal_title：Scientific reports

authors： Jun I,Lee JS,Lee JH,Lee CS,Choi SI,Gee HY,Lee MG,Kim EK

更新日期：2017-08-22 00:00:00

abstract：:The human foot and ankle system is equipped with structures that can produce mechanical work through elastic (e.g., Achilles tendon, plantar fascia) or viscoelastic (e.g., heel pad) mechanisms, or by active muscle contractions. Yet, quantifying the work distribution among various subsections of the foot and ankle can ...

journal_title：Scientific reports

authors： Takahashi KZ,Worster K,Bruening DA

更新日期：2017-11-13 00:00:00

abstract：:Intercellular adhesion plays a major role in tissue development and homeostasis. Yet, technologies to measure mature cell-cell contacts are not available. We introduce a methodology based on fluidic probe force microscopy to assess cell-cell adhesion forces after formation of mature intercellular contacts in cell mono...

journal_title：Scientific reports

authors： Sancho A,Vandersmissen I,Craps S,Luttun A,Groll J

更新日期：2017-04-10 00:00:00

abstract：:The present study aimed to explore the value of intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) in differentiating hepatocellular carcinoma (HCC) from intrahepatic cholangiocarcinoma (ICC). This study included 65 patients with malignant hepatic nodules (55 with HCC, 10 with ICC), and 17 control pati...

journal_title：Scientific reports

authors： Peng J,Zheng J,Yang C,Wang R,Zhou Y,Tao YY,Gong XQ,Wang WC,Zhang XM,Yang L

更新日期：2020-05-07 00:00:00

abstract：:The rapid increase in use of electronic-cigarettes (e-cigarettes), especially among youth, raises the urgency for regulating bodies to make informed decisions, guidance, and policy on these products. This study evaluated cardiac function in an experimental model following exposure to e-cigarettes. We subjected C57BL/6...

journal_title：Scientific reports

authors： Shi H,Fan X,Horton A,Haller ST,Kennedy DJ,Schiefer IT,Dworkin L,Cooper CJ,Tian J

更新日期：2019-03-11 00:00:00

abstract：:In this study, we propose a novel sensitive solid-based immunosensor developed on a plasmonic nanopaper platform for the detection of Escherichia coli (E. coli) bacteria. This plasmonic nanopaper that comprises of carboxylated bacterial cellulose (CBC) impregnated with gold nanoparticles (AuNP-CBC), employed as a quen...

journal_title：Scientific reports

authors： Heli B,Ajji A

更新日期：2020-09-01 00:00:00

abstract：:Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex and debilitating disease with no molecular diagnostics and no treatment options. To identify potential markers of this illness, we profiled 48 patients and 52 controls for standard laboratory tests, plasma metabolomics, blood immuno-phenotyping a...

journal_title：Scientific reports

authors： Kitami T,Fukuda S,Kato T,Yamaguti K,Nakatomi Y,Yamano E,Kataoka Y,Mizuno K,Tsuboi Y,Kogo Y,Suzuki H,Itoh M,Morioka MS,Kawaji H,Koseki H,Kikuchi J,Hayashizaki Y,Ohno H,Kuratsune H,Watanabe Y

更新日期：2020-11-16 00:00:00

abstract：:Neurogenesis of hippocampal granule cells (GCs) persists throughout mammalian life and is important for learning and memory. How newborn GCs differentiate and mature into an existing circuit during this time period is not yet fully understood. We established a method to visualize postnatally generated GCs in organotyp...

journal_title：Scientific reports

authors： Radic T,Jungenitz T,Singer M,Beining M,Cuntz H,Vlachos A,Deller T,Schwarzacher SW

更新日期：2017-03-03 00:00:00

abstract：:Efficient interventions to reduce blood triglycerides are few; newer and more tolerable intervention targets are needed. Understanding the molecular mechanisms underlying blood triglyceride levels variation is key to identifying new therapies. To explore the role of epigenetic mechanisms on triglyceride levels, a bloo...

journal_title：Scientific reports

authors： Truong V,Huang S,Dennis J,Lemire M,Zwingerman N,Aïssi D,Kassam I,Perret C,Wells P,Morange PE,Wilson M,Trégouët DA,Gagnon F

更新日期：2017-09-11 00:00:00